Neogen Sur.Medic+ Perfection 100 All In One Facial Eye Cream Versus Drunk Elephant Protini Polypeptide Cream - US
Updated on March 19, 2025
Overview
What they are
These products are both reef safe . They have a total of 14 ingredients in common
Cool Features
They both contain hyaluronic acid and peptides
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, scar healing and dark spots
Free From
They both do not contain any harsh alcohols, parabens or sulfates
What's Inside
They both contain fragrances and oils
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Neogen Sur.Medic+ Perfection 100 All In One Facial Eye Cream 123 ingredients
Drunk Elephant Protini Polypeptide Cream 58 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
Neogen Sur.Medic+ Perfection 100 All In One Facial Eye Cream 123 ingredients
Drunk Elephant Protini Polypeptide Cream 58 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
Humectant
Dipropylene Glycol
MaskingCyclopentasiloxane
Emollient
Dimethicone
Emollient
1,2-Hexanediol
Skin Conditioning
Butyrospermum Parkii Butter
Skin Conditioning
Niacinamide
Smoothing
Cyclohexasiloxane
Emollient
Polysorbate 20
Emulsifying
Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate
Skin ConditioningHydrogenated Poly(C6-14 Olefin)
EmollientCetearyl Olivate
Polyacrylate-13
Sorbitan Olivate
Emulsifying
Cetyl Alcohol
Emollient
Glyceryl Stearate
Emollient
Polyisobutene
Dimethicone/Vinyl Dimethicone Crosspolymer
Skin Conditioning
PEG-75 Stearate
Butylene Glycol
Humectant
Sodium Polyacrylate
Absorbent
Carbomer
Emulsion StabilisingTromethamine
BufferingDimethiconol
Emollient
Ceteth-20
CleansingSteareth-20
CleansingSorbitan Isostearate
Emulsifying
Ethylhexylglycerin
Skin ConditioningXanthan Gum
EmulsifyingCoptis Japonica Extract
AntimicrobialAdenosine
Skin Conditioning
Sodium Hyaluronate
Humectant
Lavandula Angustifolia Oil
Masking
Citrus Aurantium Bergamia Fruit Oil
Masking
Citrus Aurantium Dulcis Peel Oil
Masking
Aniba Rosaeodora Wood Oil
Astringent
Rosmarinus Officinalis Leaf Oil
Masking
Centella Asiatica Extract
Cleansing
Eucalyptus Globulus Leaf Oil
Perfuming
Gold
Cosmetic ColorantDextrin
AbsorbentTheobroma Cacao Extract
Skin ConditioningCollagen
Moisturising
Hyaluronic Acid
Humectant
Ceramide 3
Skin Conditioning
Cocos Nucifera Oil
Masking
Panthenol
Skin Conditioning
Hydrolyzed Collagen
Emollient
Mannitol
Humectant
Betula Platyphylla Japonica Juice
Skin Conditioning
Asiaticoside
Antioxidant
Madecassic Acid
Skin Conditioning
Asiatic Acid
Skin ConditioningLeontopodium Alpinum Callus Culture Extract
Antioxidant
Hydrolyzed Hyaluronic Acid
Humectant
Bifida Ferment Lysate
Skin Conditioning
Pvp
Emulsion StabilisingAzadirachta Indica Leaf Extract
Skin ConditioningCaprylic/Capric Triglyceride
Masking
Artemisia Annua Extract
MaskingSymphytum Officinale Leaf Extract
Skin ConditioningLecithin
Emollient
Royal Jelly Extract
Skin Conditioning
Aloe Barbadensis Leaf Extract
Emollient
Pearl Extract
Antioxidant
Propolis Extract
Skin Conditioning
Glycosyl Trehalose
Emulsion StabilisingHydrogenated Starch Hydrolysate
HumectantPalmitoyl Tripeptide-5
Skin Conditioning
Helichrysum Arenarium Extract
AntiseborrhoeicNelumbo Nucifera Flower Extract
Skin ConditioningOryza Sativa Extract
Absorbent
Calendula Officinalis Flower Extract
Masking
Saccharomyces Ferment
Skin Conditioning
Acetyl Tetrapeptide-11
Skin Conditioning
Phellinus Linteus Extract
Skin ConditioningHoney Extract
Humectant
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Arginine/Lysine Polypeptide
Skin Conditioning
Gellan Gum
Propanediol
Solvent
Usnea Barbata Extract
Zanthoxylum Piperitum Fruit Extract
Skin ConditioningPulsatilla Koreana Extract
Skin ConditioningChrysanthellum Indicum Extract
Skin ConditioningOenothera Biennis Flower Extract
AstringentCamellia Japonica Seed Extract
Skin ConditioningFragaria Chiloensis Fruit Extract
Skin Conditioning
Melissa Officinalis Leaf Extract
Skin ConditioningAesculus Hippocastanum Extract
Antioxidant
Portulaca Oleracea Extract
Skin Conditioning
Ficus Carica Fruit Extract
Humectant
Adansonia Digitata Leaf Extract
Skin ConditioningLilium Tigrinum Extract
Skin ConditioningPrunus Persica Fruit Extract
Abrasive
Achillea Millefolium Flower Extract
Antioxidant
Persea Gratissima Fruit Extract
EmollientGypsophila Paniculata Root Extract
Skin ConditioningMentha Rotundifolia Leaf Extract
TonicSambucus Nigra Fruit Extract
AstringentNelumbo Nucifera Seed Extract
Antimicrobial
Rhus Semialata Gall Extract
Skin ConditioningCananga Odorata Flower Extract
Perfuming
Jasminum Officinale Flower Extract
Masking
Dioscorea Japonica Root Extract
Skin ConditioningSimmondsia Chinensis Seed Extract
Abrasive
Beta-Glucan
Skin Conditioning
Sodium Ascorbyl Phosphate
Antioxidant
Fullerenes
AntimicrobialCopper Tripeptide-1
Skin Conditioning
Madecassoside
Antioxidant
Oligopeptide-1
Skin Conditioning
Tripeptide-1
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Tripeptide-2
Skin Conditioning
Hexapeptide-11
Skin Conditioning
Acetyl Hexapeptide-8
Humectant
Palmitoyl Tetrapeptide-7
Skin Conditioning
Palmitoyl Pentapeptide-4
Skin Conditioning
Hexapeptide-9
Skin Conditioning
Nonapeptide-1
Skin Conditioning
Disodium EDTA
Water, Glycerin, Dipropylene Glycol, Cyclopentasiloxane, Dimethicone, 1,2-Hexanediol, Butyrospermum Parkii Butter, Niacinamide, Cyclohexasiloxane, Polysorbate 20, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Hydrogenated Poly(C6-14 Olefin), Cetearyl Olivate, Polyacrylate-13, Sorbitan Olivate, Cetyl Alcohol, Glyceryl Stearate, Polyisobutene, Dimethicone/Vinyl Dimethicone Crosspolymer, PEG-75 Stearate, Butylene Glycol, Sodium Polyacrylate, Carbomer, Tromethamine, Dimethiconol, Ceteth-20, Steareth-20, Sorbitan Isostearate, Ethylhexylglycerin, Xanthan Gum, Coptis Japonica Extract, Adenosine, Sodium Hyaluronate, Lavandula Angustifolia Oil, Citrus Aurantium Bergamia Fruit Oil, Citrus Aurantium Dulcis Peel Oil, Aniba Rosaeodora Wood Oil, Rosmarinus Officinalis Leaf Oil, Centella Asiatica Extract, Eucalyptus Globulus Leaf Oil, Gold, Dextrin, Theobroma Cacao Extract, Collagen, Hyaluronic Acid, Ceramide 3, Cocos Nucifera Oil, Panthenol, Hydrolyzed Collagen, Mannitol, Betula Platyphylla Japonica Juice, Asiaticoside, Madecassic Acid, Asiatic Acid, Leontopodium Alpinum Callus Culture Extract, Hydrolyzed Hyaluronic Acid, Bifida Ferment Lysate, Pvp, Azadirachta Indica Leaf Extract, Caprylic/Capric Triglyceride, Artemisia Annua Extract, Symphytum Officinale Leaf Extract, Lecithin, Royal Jelly Extract, Aloe Barbadensis Leaf Extract, Pearl Extract, Propolis Extract, Glycosyl Trehalose, Hydrogenated Starch Hydrolysate, Palmitoyl Tripeptide-5, Helichrysum Arenarium Extract, Nelumbo Nucifera Flower Extract, Oryza Sativa Extract, Calendula Officinalis Flower Extract, Saccharomyces Ferment, Acetyl Tetrapeptide-11, Phellinus Linteus Extract, Honey Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Arginine/Lysine Polypeptide, Gellan Gum, Propanediol, Usnea Barbata Extract, Zanthoxylum Piperitum Fruit Extract, Pulsatilla Koreana Extract, Chrysanthellum Indicum Extract, Oenothera Biennis Flower Extract, Camellia Japonica Seed Extract, Fragaria Chiloensis Fruit Extract, Melissa Officinalis Leaf Extract, Aesculus Hippocastanum Extract, Portulaca Oleracea Extract, Ficus Carica Fruit Extract, Adansonia Digitata Leaf Extract, Lilium Tigrinum Extract, Prunus Persica Fruit Extract, Achillea Millefolium Flower Extract, Persea Gratissima Fruit Extract, Gypsophila Paniculata Root Extract, Mentha Rotundifolia Leaf Extract, Sambucus Nigra Fruit Extract, Nelumbo Nucifera Seed Extract, Rhus Semialata Gall Extract, Cananga Odorata Flower Extract, Jasminum Officinale Flower Extract, Dioscorea Japonica Root Extract, Simmondsia Chinensis Seed Extract, Beta-Glucan, Sodium Ascorbyl Phosphate, Fullerenes, Copper Tripeptide-1, Madecassoside, Oligopeptide-1, Tripeptide-1, Palmitoyl Tripeptide-1, Tripeptide-2, Hexapeptide-11, Acetyl Hexapeptide-8, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Hexapeptide-9, Nonapeptide-1, Disodium EDTA
Water
Skin ConditioningDicaprylyl Carbonate
EmollientGlycerin
Humectant
Cetearyl Alcohol
Emollient
Cetearyl Olivate
Sorbitan Olivate
Emulsifying
Sclerocarya Birrea Seed Oil
Humectant
Bacillus/Folic Acid Ferment Filtrate Extract
Antioxidant
Nymphaea Alba Root Extract
Skin ConditioningSh-Oligopeptide-1
Skin Conditioning
Sh-Oligopeptide-2
Skin Conditioning
Sh-Polypeptide-1
Skin Conditioning
Sh-Polypeptide-9
Skin Conditioning
Sh-Polypeptide-11
Copper Palmitoyl Heptapeptide-14
Skin Conditioning
Heptapeptide-15 Palmitate
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Alanine
MaskingArginine
Masking
Glycine
Buffering
Histidine
Humectant
Isoleucine
Skin ConditioningPhenylalanine
Masking
Proline
Skin ConditioningSerine
Masking
Threonine
Valine
MaskingAcetyl Glutamine
Skin ConditioningCoconut Alkanes
Emollient
Coco-Caprylate/Caprate
Emollient
Sodium Hyaluronate
Humectant
Aspartic Acid
Masking
Linoleic Acid
Cleansing
Linolenic Acid
Cleansing
Lecithin
Emollient
Butylene Glycol
Humectant
Polyvinyl Alcohol
Sodium Lactate
BufferingSodium PCA
Humectant
PCA
Humectant
Sorbitan Isostearate
Emulsifying
Carbomer
Emulsion StabilisingPolysorbate 20
Emulsifying
Polysorbate 60
Emulsifying
Lactic Acid/Glycolic Acid Copolymer
Skin ConditioningHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingXanthan Gum
EmulsifyingIsomalt
Humectant1,2-Hexanediol
Skin Conditioning
Caprylyl Glycol
EmollientChlorphenesin
Antimicrobial
Phenoxyethanol
Preservative
Tocopherol
Antioxidant
Sodium Benzoate
Masking
Phenylpropanol
Masking
Glyceryl Caprylate
EmollientSymphytum Officinale Callus Culture Extract
Skin ConditioningWater, Dicaprylyl Carbonate, Glycerin, Cetearyl Alcohol, Cetearyl Olivate, Sorbitan Olivate, Sclerocarya Birrea Seed Oil, Bacillus/Folic Acid Ferment Filtrate Extract, Nymphaea Alba Root Extract, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Alanine, Arginine, Glycine, Histidine, Isoleucine, Phenylalanine, Proline, Serine, Threonine, Valine, Acetyl Glutamine, Coconut Alkanes, Coco-Caprylate/Caprate, Sodium Hyaluronate, Aspartic Acid, Linoleic Acid, Linolenic Acid, Lecithin, Butylene Glycol, Polyvinyl Alcohol, Sodium Lactate, Sodium PCA, PCA, Sorbitan Isostearate, Carbomer, Polysorbate 20, Polysorbate 60, Lactic Acid/Glycolic Acid Copolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Xanthan Gum, Isomalt, 1,2-Hexanediol, Caprylyl Glycol, Chlorphenesin, Phenoxyethanol, Tocopherol, Sodium Benzoate, Phenylpropanol, Glyceryl Caprylate, Symphytum Officinale Callus Culture Extract
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCarbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.
A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.
Cetearyl Olivate is an emulsifier and texture enhancer. It is derived from the fatty acids of olive oil and Cetearyl alcohol, and is biodegradable.
As an emulsifier, it is used to prevent oils and waters from separating. It can also
Manufacturers use the name Olivem 1000. This ingredient has been found to preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria. This ingredient is grouped with Sorbitan Olivate under the name Olivem 1000.
Learn more about Cetearyl OlivateGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinLecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.
This ingredient has emollient and emulsifying properties.
As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.
As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.
This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.
Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.
We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.
Learn more about LecithinPalmitoyl Tetrapeptide-7 is a lab-made peptide with anti-inflammatory and skin-repairing benefits. It's made up of four amino acids (glycine, glutamine, proline, and arginine) and palmitic acid (which helps it penetrate skin more effectively).
This ingredient helps reduce inflammation by limiting the production of interleukin-6 (IL-6), a chemical that triggers inflammatory responses, particularly after UV exposure.
Less inflammation = slower collagen breakdown and a longer-lasting, youthful appearance.
Palmitoyl Tetrapeptide-7 also stimulates collagen production and supports a healthier skin barrier.
Over time, this can improve skin firmness, hydration, and reduce the appearance of fine lines. It’s commonly paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.
This ingredient has been shown to be effective and safe in cosmetic use and you'll typically find it in small amounts (less than 0.01%).
Due to its palmitic acid base, it may not be safe for Malassezia folliculitis.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tetrapeptide-7Palmitoyl Tripeptide-1 is also known as pal-GHK. It is made up of 3 amino acids and palmitic acid, a fatty acid that helps it absorb into skin more easily.
This peptide is as a signal peptide, meaning it tells the skin to produce more collagen. Collagen is the key protein that helps form the skin's structure and keep it plump, firm, and hydrated.
By boosting collagen production, this ingredient supports a stronger skin barrier and helps reduce the appearance of wrinkles.
You'll most likely see this ingredient paired with Palmitoyl Tetrapeptide-7 in the well-known Matrixyl 3000 complex. While results from in-house testing should be viewed cautiously, this peptide duo is among the most studied and widely used in modern skincare.
Due to its palmitic acid base, this ingredient may not be safe for Malassezia folliculitis.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tripeptide-1Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateSorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.
As an emulsifier, Sorbitan Isostearate prevents oils and water from separating.
Due to its isostearic acid base, it may not be safe for Malassezia or fungal acne.
Learn more about Sorbitan IsostearateSorbitan Olivate is created from the fatty acids in olive oil and sorbitol.
This ingredient is an oil in water emulsifier. It helps stabilize a product by preventing oils and waters from separating. Sorbitan Olivate also helps hydrate the skin.
Manufacturers sell sorbitan olivate under the name OliveM 1000. OliveM 1000 a multifunctional ingredient. It is self-emulsifying. According to a manufacturer, OliveM 1000 does not disrupt natural skin biome.
Due to its olive oil base, this ingredient may not be fungal-acne safe.
Learn more about Sorbitan OlivateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumIngredient Ratings
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When to use
Neogen Sur.Medic+ Perfection 100 All In One Facial Eye Cream 123 ingredients
Drunk Elephant Protini Polypeptide Cream 58 ingredients
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Neogen Sur.Medic+ Perfection 100 All In One Facial Eye Cream 123 ingredients
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