PCA
Explained
PCA is an amino acid derivative and one of the star players in your skin's own Natural Moisturizing Factor (NMF).
The NMF is the built-in cocktail of small molecules that keeps your outer layer of skin hydrated and your body makes it naturally.
This is why it works so well topically; PCA is a humectant that holds water in the stratum corneum and studies link higher skin PCA levels to better hydration + lower water loss. Interestingly, people show more PCA in summer and in normal vs dry skin.
Most of the benefits of this ingredient are related to hydration, softness, and barrier support.
A long-running review found that formulas with at least 2% PCA or its salts improved dry skin over both the short and long term. And the zinc salt is also used for its mild antimicrobial and astringent properties.
The salt forms are more common in cosmetics (like sodium PCA).
This ingredient is compatible with basically everything and pairs well with other humectants like glycerin or hyaluronic acid.
Usage-wise, it's typically used at low percentages (~0.2-2%).
The Cosmetic Ingredient Review Expert Panel has concluded PCA and its salts are safe as used and is non-irritating on skin even at high concentrations.
See all 1,161 products with PCA
