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Palmitoyl Tetrapeptide-7

Explained

Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging".

"Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age.

This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin.

Clinical testing showed statistically significant improvements in:

  • Skin elasticity
  • A reduction in deep wrinkles
  • Improved skin texture

Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid.

You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.

A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation results in clinical panels.

Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.

See all 2,476 products with Palmitoyl Tetrapeptide-7

Users who like it
86%
Users who avoid it
14%

What it does

Skin Conditioning To hydrate and soften skin

Prevalence

Uncommon Percentage of products that contain it
1.9%
Top categories
Treatments
Moisturizers
Eye Care
Position Predominant list placement
Bottom 25%
Concentration Concentrations we've seen
95%

References

CosIng Data

CosIng ID 56918
INCI Name PALMITOYL TETRAPEPTIDE-7
EC #  -
All Functions Skin Conditioning