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Missha Time Revolution Night Repair Ampoule 5x Versus MEDI-PEEL Cindella Multi-Antioxidant Ampoule

Ampoule
Ampoule
Korean Brand South Korea
Korean Brand South Korea

Updated on December 21, 2024

Overview

What they are

These products are both reef safe ampoules. They have a total of 14 ingredients in common

Cool Features

They both contain ceramides, hyaluronic acid, niacinamide and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, parabens, silicones or sulfates

What's Inside

They both contain common allergens, fragrances and oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Time Revolution Night Repair Ampoule 5x

Bifida Ferment Lysate

Skin Conditioning
Helps hydrate Dry Skin Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

1,2-Hexanediol

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Betaine

Humectant
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots Icon

Propanediol

Solvent

Water

Skin Conditioning

Chondrus Crispus Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Saccharum Officinarum Extract

Moisturising

Pentylene Glycol

Skin Conditioning

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Polyquaternium-51

Skin Conditioning

Diethoxyethyl Succinate

Solvent

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Polyglyceryl-10 Laurate

Skin Conditioning
Not safe for Fungal Acne Icon

Hydrogenated Lecithin

Emulsifying

Carbomer

Emulsion Stabilising
1 / 0

Lactobacillus Ferment

Skin Conditioning

Lactobacillus Ferment Lysate

Skin Conditioning
Not safe for Fungal Acne Icon

Leuconostoc/Radish Root Ferment Filtrate

Antimicrobial
Not safe for Fungal Acne Icon

Lactococcus Ferment

Skin Conditioning

Lactobacillus/Acerola Cherry Ferment

Skin Protecting

Lactobacillus/Soybean Ferment Extract

Skin Conditioning

Lactobacillus/Punica Granatum Fruit Ferment Extract

Skin Conditioning

Lactococcus Ferment Lysate

Skin Conditioning

Bifida Ferment Filtrate

Skin Conditioning

Tromethamine

Buffering

Solanum Melongena Fruit Extract

Skin Conditioning

Daucus Carota Sativa Root Extract

Skin Conditioning

Brassica Oleracea Capitata Leaf Extract

Skin Conditioning

Beta Vulgaris Root Extract

Skin Conditioning

Vaccinium Angustifolium Fruit Extract

Skin Protecting

Ethylhexylglycerin

Skin Conditioning

Xanthan Gum

Emulsifying

Aspergillus Ferment

Skin Conditioning

Swiftlet Nest Extract

Skin Conditioning

Dextrin

Absorbent

Theobroma Cacao Extract

Skin Conditioning

Adenosine

Skin Conditioning
Good for Minimizing Pores IconGood for Scar Healing Icon

Citrus Aurantium Bergamia Fruit Oil

Masking
Fragrance IconOil Icon

Pelargonium Graveolens Flower Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen Icon

Citrus Aurantium Dulcis Peel Oil

Masking
Oil Icon

Lavandula Angustifolia Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen Icon

Anthemis Nobilis Flower Oil

Masking
Fragrance IconOil Icon

Santalum Album Oil

Masking
Oil IconMay cause irritation IconEU Allergen Icon

Limonene

Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Disodium EDTA

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Lupinus Albus Seed Extract

Skin Conditioning

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon
Cindella Multi-Antioxidant Ampoule

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Propanediol

Solvent

1,2-Hexanediol

Skin Conditioning

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Caprylic/Capric Triglyceride

Masking

Methyl Gluceth-20

Humectant

Ammonium Acryloyldimethyltaurate/Vp Copolymer

PEG-60 Hydrogenated Castor Oil

Emulsifying
Oil IconNot safe for Fungal Acne Icon

Gelatin

Sodium Polyacrylate

Absorbent

Parfum

Masking
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Adenosine

Skin Conditioning
Good for Minimizing Pores IconGood for Scar Healing Icon

Cellulose Gum

Emulsion Stabilising
0 / 0

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Disodium EDTA

Lithospermum Erythrorhizon Root Extract

Skin Conditioning

Soluble Proteoglycan

Skin Conditioning

Salmon Egg Extract

Limonene

Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Linalool

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Hexyl Cinnamal

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

CI 15510

Cosmetic Colorant

CI 17200

Cosmetic Colorant
1 / 2

Glutathione

Good for Dark Spots Icon

Biotin

Antiseborrhoeic

Ascorbic Acid

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon

Tremella Fuciformis Extract

Humectant

Lactobacillus/Rye Flour Ferment

Skin Conditioning

Lactobacillus/Soymilk Ferment Filtrate

Skin Conditioning

Bacillus/Soybean Ferment Extract

Skin Conditioning

Maltodextrin

Absorbent

Calcium Pantothenate

Sodium Starch Octenylsuccinate

Absorbent

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Aloe Barbadensis Leaf Extract

Emollient
Helps reduce Skin Redness IconHelps reduce irritation Icon

Diospyros Kaki Leaf Extract

Skin Protecting

Sodium Ascorbyl Phosphate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Sodium Hyaluronate Crosspolymer

Humectant
Hyaluronic Acid Icon

Centella Asiatica Extract

Cleansing
Helps reduce Skin Redness IconHelps reduce irritation Icon

Rhizobian Gum

Hydrolyzed Glycosaminoglycans

Humectant

Scutellaria Baicalensis Root Extract

Astringent

Glycine

Buffering
Helps hydrate Dry Skin Icon

Acacia Senegal Gum

Masking

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Pyridoxine Hcl

Skin Conditioning

Polygonum Cuspidatum Root Extract

Antioxidant
Antioxidant Icon

Serine

Masking

Glutamic Acid

Humectant

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Glycyrrhiza Glabra Root Extract

Bleaching
Good for Dark Spots Icon

Origanum Vulgare Leaf Extract

Skin Conditioning

Palmitoyl Tripeptide-5

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Chamaecyparis Obtusa Leaf Extract

Skin Conditioning

Salix Alba Bark Extract

Astringent
Good for Oily Skin Icon

Benzyl Glycol

Solvent

Aspartic Acid

Masking

Leucine

Skin Conditioning

Lactobacillus/Soybean Ferment Extract

Skin Conditioning

Rosmarinus Officinalis Leaf Extract

Antimicrobial

Riboflavin

Cosmetic Colorant

Chamomilla Recutita Flower Extract

Masking
Helps reduce Skin Redness IconHelps reduce irritation Icon

Cyanocobalamin

Skin Conditioning

Portulaca Oleracea Extract

Skin Conditioning

Cinnamomum Cassia Bark Extract

Masking
May worsen Eczema Icon

Thiamine Hcl

Masking

Pantothenic Acid

Skin Conditioning

Folic Acid

Skin Conditioning

Pyridoxine

Skin Conditioning

Alanine

Masking

Lysine

Skin Conditioning

Hydrogenated Lecithin

Emulsifying

Arginine

Masking
Good for Scar Healing IconNot safe for Fungal Acne Icon

Tyrosine

Masking

Phenylalanine

Masking

Valine

Masking

Caprylyl Glycol

Emollient

Threonine

Proline

Skin Conditioning

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Isoleucine

Skin Conditioning

Histidine

Humectant

Methionine

Skin Conditioning

Cysteine

Antioxidant
Antioxidant Icon

Silica

Abrasive
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon

Ethylhexylglycerin

Skin Conditioning

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Skin Conditioning
Peptide Icon

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Raspberry Ketone

Masking
Fragrance Icon

Water, Glycerin, Propanediol, 1,2-Hexanediol, Niacinamide, Butylene Glycol, Caprylic/Capric Triglyceride, Methyl Gluceth-20, Ammonium Acryloyldimethyltaurate/Vp Copolymer, PEG-60 Hydrogenated Castor Oil, Gelatin, Sodium Polyacrylate, Parfum, Citric Acid, Adenosine, Cellulose Gum, Sodium Hyaluronate, Disodium EDTA, Lithospermum Erythrorhizon Root Extract, Soluble Proteoglycan, Salmon Egg Extract, Limonene, Linalool, Hexyl Cinnamal, CI 15510, CI 17200, Glutathione, Biotin, Ascorbic Acid, Tremella Fuciformis Extract, Lactobacillus/Rye Flour Ferment, Lactobacillus/Soymilk Ferment Filtrate, Bacillus/Soybean Ferment Extract, Maltodextrin, Calcium Pantothenate, Sodium Starch Octenylsuccinate, Ceramide NP, Aloe Barbadensis Leaf Extract, Diospyros Kaki Leaf Extract, Sodium Ascorbyl Phosphate, Sodium Hyaluronate Crosspolymer, Centella Asiatica Extract, Rhizobian Gum, Hydrolyzed Glycosaminoglycans, Scutellaria Baicalensis Root Extract, Glycine, Acacia Senegal Gum, Tocopheryl Acetate, Pyridoxine Hcl, Polygonum Cuspidatum Root Extract, Serine, Glutamic Acid, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Origanum Vulgare Leaf Extract, Palmitoyl Tripeptide-5, Chamaecyparis Obtusa Leaf Extract, Salix Alba Bark Extract, Benzyl Glycol, Aspartic Acid, Leucine, Lactobacillus/Soybean Ferment Extract, Rosmarinus Officinalis Leaf Extract, Riboflavin, Chamomilla Recutita Flower Extract, Cyanocobalamin, Portulaca Oleracea Extract, Cinnamomum Cassia Bark Extract, Thiamine Hcl, Pantothenic Acid, Folic Acid, Pyridoxine, Alanine, Lysine, Hydrogenated Lecithin, Arginine, Tyrosine, Phenylalanine, Valine, Caprylyl Glycol, Threonine, Proline, Hydrolyzed Hyaluronic Acid, Isoleucine, Histidine, Methionine, Cysteine, Silica, Ethylhexylglycerin, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Hyaluronic Acid, Raspberry Ketone

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.
  • It has mild preservative properties.

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Smoothing

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.

This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

This ingredient is created by fermenting soybean extract with the bacteria, lactobacillus.

Some studies have shown it to have antioxidant properties. One study found this ingredient to have stronger properties than non-fermented soybean extract.

Another study found in increase of isoflavones, amino acids, and peptides in fermented soy milk.

Learn more about Lactobacillus/Soybean Ferment Extract
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine
Perfuming, Solvent

Limonene is a fragrance that adds scent and taste to a formulation.

It's found in the peel oil of citrus fruits and other plants such as lavender and eucalyptus. The scent of limonene is generally described as "sweet citrus".

Limonene acts as an antioxidant, meaning it helps neutralize free radicals.

When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.

The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.

Learn more about Limonene

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Skin Conditioning

Ceramide NP is a type of ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here: Ceramide AP Ceramide EOP

Learn more about Ceramide NP

When to use

137 Routines
10% use in am
90% use in pm
90% use every day
When to use See routines that use it ->
1 Routine
100% use in am
0% use in pm
100% use every day

Reviews

Here's what our community thinks

Missha Time Revolution Night Repair Ampoule 5x 54 ingredients

4.7 /5
from 3 ratings
Absorbs Well (2) Great Value (2) Hydrating (2)
gfunkpsych's avatar

gfunkpsych

10 months ago
Review

I have Eczema and have to be very careful about skincare products with any scents, so I was hesitant to purchase this serum. I had read that it was a dupe for the Estee Lauder’s iconic night repair serum and decided it to give it a go. To my pleasant surprise I love using it every night because of its scent. I also love it for the soft hydrated skin in the morning.

#great value
#works well
bujanabrahimi's avatar

🍯 Boo

8 months ago
Review

I got it to replace estee lauders advanced night repair serum. Tbh I didn’t see much difference in terms of quality but yet again none of them did wonders but none of them did harm.
Not purchasing again because now I have a much simpler routine.

#great value
#hydrating
#light
#absorbs well

MEDI-PEEL Cindella Multi-Antioxidant Ampoule 92 ingredients

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