Dr. Althea 345 Relief Cream Versus Centellian24 Madeca Cream Hydra 3x Formula
Updated on April 29, 2025
Overview
What they are
These products are both vegan, cruelty-free, and reef safe general moisturizers. They have a total of 12 ingredients in common
Cool Features
They both contain ceramides, hyaluronic acid, peptides and Vitamin E
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots
Free From
They both do not contain any parabens or sulfates
What's Inside
They both contain common allergens, fragrances, oils and silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Dr. Althea 345 Relief Cream 56 ingredients
Centellian24 Madeca Cream Hydra 3x Formula 93 ingredients
What's inside
What's inside
At a glance
Click on any of the items below to learn more
Dr. Althea 345 Relief Cream 56 ingredients
Centellian24 Madeca Cream Hydra 3x Formula 93 ingredients
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningPropanediol
Solvent
Glycerin
Humectant
Cyclohexasiloxane
Emollient
1,2-Hexanediol
Skin Conditioning
Caprylic/Capric Triglyceride
Masking
Niacinamide
Smoothing
Panthenol
Skin Conditioning
Polyglycerin-3
Humectant
Polyglyceryl-10 Stearate
Skin Conditioning
Hydrogenated Poly(C6-14 Olefin)
EmollientHydrogenated Polydecene
EmollientLaminaria Japonica Extract
Skin Protecting
Eclipta Prostrata Leaf Extract
Skin ConditioningMelia Azadirachta Flower Extract
Skin ConditioningHouttuynia Cordata Extract
Skin Conditioning
Melia Azadirachta Leaf Extract
Skin ConditioningOenothera Biennis Flower Extract
AstringentCurcuma Longa Root Extract
Masking
Ocimum Sanctum Leaf Extract
Skin Conditioning
Calendula Officinalis Flower Extract
Masking
Agave Tequilana Leaf Extract
AstringentSargassum Fulvellum Extract
Skin ConditioningCorallina Officinalis Extract
Skin Conditioning
Lavandula Angustifolia Flower Extract
Cleansing
Centella Asiatica Leaf Extract
Skin Conditioning
Opuntia Ficus-Indica Stem Extract
Skin Conditioning
Gardenia Florida Fruit Extract
Skin ConditioningPerilla Ocymoides Leaf Extract
TonicHibiscus Sabdariffa Flower Extract
Skin ConditioningSodium Hyaluronate
Humectant
Hydrogenated Lecithin
Emulsifying
Empetrum Nigrum Fruit Juice
Skin ConditioningDicaprylyl Carbonate
EmollientC14-22 Alcohols
Emulsion StabilisingAmmonium Acryloyldimethyltaurate/Vp Copolymer
Polymethylsilsesquioxane
Dipropylene Glycol
MaskingButylene Glycol
Humectant
C12-20 Alkyl Glucoside
EmulsifyingAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingEthylhexylglycerin
Skin ConditioningPolyquaternium-51
Skin Conditioning
Tromethamine
BufferingFructooligosaccharides
Humectant
Adenosine
Skin Conditioning
Beta-Glucan
Skin Conditioning
Glycine Soja Sterols
Emollient
PEG-40 Castor Oil
Emulsifying
Hydrolyzed Hyaluronic Acid
Humectant
Resveratrol
Antioxidant
Tocopherol
Antioxidant
Ceramide NP
Skin Conditioning
Oligopeptide-1
Skin Conditioning
Phenoxyethanol
Preservative
Potassium Sorbate
Preservative
Water, Propanediol, Glycerin, Cyclohexasiloxane, 1,2-Hexanediol, Caprylic/Capric Triglyceride, Niacinamide, Panthenol, Polyglycerin-3, Polyglyceryl-10 Stearate, Hydrogenated Poly(C6-14 Olefin), Hydrogenated Polydecene, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Melia Azadirachta Flower Extract, Houttuynia Cordata Extract, Melia Azadirachta Leaf Extract, Oenothera Biennis Flower Extract, Curcuma Longa Root Extract, Ocimum Sanctum Leaf Extract, Calendula Officinalis Flower Extract, Agave Tequilana Leaf Extract, Sargassum Fulvellum Extract, Corallina Officinalis Extract, Lavandula Angustifolia Flower Extract, Centella Asiatica Leaf Extract, Opuntia Ficus-Indica Stem Extract, Gardenia Florida Fruit Extract, Perilla Ocymoides Leaf Extract, Hibiscus Sabdariffa Flower Extract, Sodium Hyaluronate, Hydrogenated Lecithin, Empetrum Nigrum Fruit Juice, Dicaprylyl Carbonate, C14-22 Alcohols, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Polymethylsilsesquioxane, Dipropylene Glycol, Butylene Glycol, C12-20 Alkyl Glucoside, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ethylhexylglycerin, Polyquaternium-51, Tromethamine, Fructooligosaccharides, Adenosine, Beta-Glucan, Glycine Soja Sterols, PEG-40 Castor Oil, Hydrolyzed Hyaluronic Acid, Resveratrol, Tocopherol, Ceramide NP, Oligopeptide-1, Phenoxyethanol, Potassium Sorbate
Centella Asiatica Extract
Cleansing
Butylene Glycol
Humectant
Squalane
Emollient
Alcohol Denat.
Antimicrobial
Butyrospermum Parkii Butter
Skin Conditioning
Hydrogenated Poly(C6-14 Olefin)
EmollientGlyceryl Stearate
Emollient
Glycerin
Humectant
Caprylic/Capric Triglyceride
Masking
Caprylic/Capric/Myristic/Stearic Triglyceride
EmollientCetearyl Alcohol
Emollient
PEG-40 Stearate
Emulsifying
Cyclopentasiloxane
Emollient
Helianthus Annuus Seed Oil
Emollient
Citrus Aurantium Bergamia Fruit Oil
Masking
Olea Europaea Fruit Oil
Masking
Lilium Speciosum Flower Oil
Masking
Orange Roughy Oil
Skin Conditioning
Rose Flower Oil
Masking
Citrus Iyo Peel Oil
Lavandula Angustifolia Oil
Masking
Cedrus Atlantica Bark Oil
Masking
Rosa Damascena Flower Oil
Masking
Hydrolyzed Vegetable Protein
Skin ConditioningXylitylglucoside
Humectant
Jasminum Officinale Oil
Masking
Hyaluronic Acid
Humectant
Artemisia Vulgaris Extract
Skin Conditioning
Crithmum Maritimum Callus Culture Filtrate
Skin ProtectingXylitol
Humectant
Ferula Galbaniflua Resin Oil
Antimicrobial
Hydrolyzed Lupine Seed Extract
Skin ConditioningChlorella Vulgaris Extract
Skin Conditioning
Gold
Cosmetic ColorantRhododendron Weyrichii Extract
Skin ConditioningVanilla Planifolia Fruit Extract
Skin Conditioning
Camellia Sinensis Leaf Extract
Antimicrobial
Glycyrrhiza Glabra Root Extract
Bleaching
Rosa Alba Leaf/Stem Extract
HumectantChamomilla Recutita Extract
Skin Conditioning
Rosmarinus Officinalis Leaf Extract
AntimicrobialPinus Pinaster Leaf Extract
Skin ConditioningOriganum Vulgare Leaf Extract
Skin ConditioningSalix Alba Bark Extract
Astringent
Betula Alba Bark Extract
Masking
Lactobacillus
Skin ConditioningPumice Extract
Antioxidant
Synthetic Beeswax
Emulsion Stabilising
Cyclohexasiloxane
Emollient
PEG-100 Stearate
1,2-Hexanediol
Skin Conditioning
Polyacrylate-13
Asiaticoside
Antioxidant
PEG-10 Dimethicone
Skin Conditioning
Madecassic Acid
Skin Conditioning
PEG-30 Dipolyhydroxystearate
Emulsifying
Water
Skin ConditioningPolyisobutene
Palmitic Acid
Emollient
Asiatic Acid
Skin ConditioningCaprylyl Glycol
EmollientStearic Acid
Cleansing
Saccharide Isomerate
Humectant
Tocopheryl Acetate
Antioxidant
Ethylhexylglycerin
Skin ConditioningOctanediol
Polysorbate 20
Emulsifying
Adenosine
Skin Conditioning
Sorbitan Isostearate
Emulsifying
Myristic Acid
Cleansing
Arachidic Acid
Cleansing
Dipropylene Glycol
MaskingCitric Acid
Buffering
Sodium Citrate
BufferingLauric Acid
Cleansing
Maltodextrin
Absorbent
Tocopherol
Antioxidant
Anhydroxylitol
Humectant
Dimethicone/Vinyl Dimethicone Crosspolymer
Skin Conditioning
Hydroxyacetophenone
Antioxidant
Sorbitan Laurate
Emulsifying
Ceramide NP
Skin Conditioning
Phytosphingosine
Skin Conditioning
Hydroxyethylcellulose
Emulsion StabilisingAcetyl Dipeptide-1 Cetyl Ester
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Disodium EDTA
Carbomer
Emulsion StabilisingLimonene
Perfuming
Linalool
Perfuming
Citronellol
Perfuming
Geraniol
Perfuming
Centella Asiatica Extract, Butylene Glycol, Squalane, Alcohol Denat., Butyrospermum Parkii Butter, Hydrogenated Poly(C6-14 Olefin), Glyceryl Stearate, Glycerin, Caprylic/Capric Triglyceride, Caprylic/Capric/Myristic/Stearic Triglyceride, Cetearyl Alcohol, PEG-40 Stearate, Cyclopentasiloxane, Helianthus Annuus Seed Oil, Citrus Aurantium Bergamia Fruit Oil, Olea Europaea Fruit Oil, Lilium Speciosum Flower Oil, Orange Roughy Oil, Rose Flower Oil, Citrus Iyo Peel Oil, Lavandula Angustifolia Oil, Cedrus Atlantica Bark Oil, Rosa Damascena Flower Oil, Hydrolyzed Vegetable Protein, Xylitylglucoside, Jasminum Officinale Oil, Hyaluronic Acid, Artemisia Vulgaris Extract, Crithmum Maritimum Callus Culture Filtrate, Xylitol, Ferula Galbaniflua Resin Oil, Hydrolyzed Lupine Seed Extract, Chlorella Vulgaris Extract, Gold, Rhododendron Weyrichii Extract, Vanilla Planifolia Fruit Extract, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Rosa Alba Leaf/Stem Extract, Chamomilla Recutita Extract, Rosmarinus Officinalis Leaf Extract, Pinus Pinaster Leaf Extract, Origanum Vulgare Leaf Extract, Salix Alba Bark Extract, Betula Alba Bark Extract, Lactobacillus, Pumice Extract, Synthetic Beeswax, Cyclohexasiloxane, PEG-100 Stearate, 1,2-Hexanediol, Polyacrylate-13, Asiaticoside, PEG-10 Dimethicone, Madecassic Acid, PEG-30 Dipolyhydroxystearate, Water, Polyisobutene, Palmitic Acid, Asiatic Acid, Caprylyl Glycol, Stearic Acid, Saccharide Isomerate, Tocopheryl Acetate, Ethylhexylglycerin, Octanediol, Polysorbate 20, Adenosine, Sorbitan Isostearate, Myristic Acid, Arachidic Acid, Dipropylene Glycol, Citric Acid, Sodium Citrate, Lauric Acid, Maltodextrin, Tocopherol, Anhydroxylitol, Dimethicone/Vinyl Dimethicone Crosspolymer, Hydroxyacetophenone, Sorbitan Laurate, Ceramide NP, Phytosphingosine, Hydroxyethylcellulose, Acetyl Dipeptide-1 Cetyl Ester, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Disodium EDTA, Carbomer, Limonene, Linalool, Citronellol, Geraniol
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Â
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesÂ
Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.
Studies have found adenosine may also help with wound healing.
In skincare products, Adenosine is usually derived from yeast.
Learn more about AdenosineButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolThis ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.
Learn more about Caprylic/Capric TriglycerideCeramide NP is a type of ceramide.
Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.
Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.
If you would like to eat ceramides, sweet potatoes contain a small amount.
Read more about other common types of ceramides here:
Ceramide AP
Ceramide EOP
Cyclohexasiloxane is a type of silicone more commonly known as D6. It is an emollient and solvent.
Cyclohexasiloxane is used to evenly distribute ingredients throughout the product. When applied to the skin, Cyclohexasiloxane evaporates and leaves behind a silky feel.
As an emollient, it can help the skin feel soft and hydrated. It is also used to reduce frizz in hair products.
Learn more about CyclohexasiloxaneDipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.
Dipropylene Glycol helps dissolve and evenly distribute ingredients. It also helps decrease viscosity and thin out texture.
As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.
Studies show Dipropylene Glycol is considered safe to use in skincare.
Learn more about Dipropylene GlycolEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinWe don't have a description for Hydrogenated Poly(C6-14 Olefin) yet.
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterIngredient Ratings
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Dr. Althea 345 Relief Cream 56 ingredients
Centellian24 Madeca Cream Hydra 3x Formula 93 ingredients
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