Peter Thomas Roth Peptide Skinjection Moisture Infusion Cream Versus IMAGE skincare Ageless Total Repair Crème
This anti-aging moisturizer is formulated around Squalane and Hexapeptide-11 to soften the look of wrinkles and hydrate skin.
This anti-aging moisturizer is formulated around Glycolic Acid and Retinol to soften the look of wrinkles and refine skin texture.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
HumectantDimethicone
EmollientOlive Oil Decyl Esters
Glycereth-26
HumectantSqualane
EmollientButylene Glycol
HumectantBehenyl Alcohol
EmollientPolysilicone-11
Batyl Alcohol
EmollientSimmondsia Chinensis Seed Oil
EmollientHexapeptide-11
Skin ConditioningDipeptide Diaminobutyroyl Benzylamide Diacetate
Skin ConditioningPalmitoyl Tripeptide-5
Skin ConditioningTripeptide-10 Citrulline
Skin ConditioningAcetyl Hexapeptide-1
Skin ConditioningAcetyl Tetrapeptide-11
Skin ConditioningAcetyl Hexapeptide-8
HumectantPalmitoyl Hexapeptide-12
Skin ConditioningAcetyl Tetrapeptide-9
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningAcetyl Tetrapeptide-2
Skin ConditioningAcetyl Octapeptide-3
HumectantPalmitoyl Hexapeptide-19
Skin ConditioningTrifluoroacetyl Tripeptide-2
Skin ConditioningTripeptide-1
Skin ConditioningPalmitoyl Oligopeptide
CleansingPalmitoyl Tripeptide-1
Skin ConditioningNatto Gum
Sodium Polyglutamate
HumectantSqualene
EmollientMica
Cosmetic ColorantSodium Hyaluronate
HumectantSorbic Acid
PreservativeTocopherol
AntioxidantCereus Grandiflorus Flower Extract
Skin ConditioningPseudoalteromonas Ferment Extract
HumectantLeuconostoc/Radish Root Ferment Filtrate
AntimicrobialMagnesium Chloride
Phenoxyethanol
PreservativeCetyl Alcohol
EmollientStearyl Alcohol
EmollientTrehalose
HumectantGlyceryl Stearate
EmollientSilanetriol Trehalose Ether
EmollientMannitol
HumectantPhytosterols
Skin ConditioningAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingCaprylic/Capric Triglyceride
MaskingHydrogenated Lecithin
EmulsifyingPolyglyceryl-10 Myristate
Skin ConditioningPolysorbate 20
EmulsifyingDimethyl Isosorbide
SolventSodium Benzoate
MaskingPotassium Sorbate
PreservativeCaprylyl Glycol
EmollientSodium Hydroxide
BufferingLaureth-12
EmulsifyingHydrolyzed Wheat Protein
Skin ConditioningLecithin
EmollientDisodium Phosphate
BufferingHydrolyzed Soy Protein
HumectantCarbomer
Emulsion StabilisingDextran
Ethylhexylglycerin
Skin ConditioningSodium Lactate
BufferingTetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
Skin ConditioningSodium Phosphate
BufferingXanthan Gum
EmulsifyingTriethanolamine
BufferingAcrylates Copolymer
Water, Glycerin, Dimethicone, Olive Oil Decyl Esters, Glycereth-26, Squalane, Butylene Glycol, Behenyl Alcohol, Polysilicone-11, Batyl Alcohol, Simmondsia Chinensis Seed Oil, Hexapeptide-11, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tripeptide-5, Tripeptide-10 Citrulline, Acetyl Hexapeptide-1, Acetyl Tetrapeptide-11, Acetyl Hexapeptide-8, Palmitoyl Hexapeptide-12, Acetyl Tetrapeptide-9, Palmitoyl Tetrapeptide-7, Acetyl Tetrapeptide-2, Acetyl Octapeptide-3, Palmitoyl Hexapeptide-19, Trifluoroacetyl Tripeptide-2, Tripeptide-1, Palmitoyl Oligopeptide, Palmitoyl Tripeptide-1, Natto Gum, Sodium Polyglutamate, Squalene, Mica, Sodium Hyaluronate, Sorbic Acid, Tocopherol, Cereus Grandiflorus Flower Extract, Pseudoalteromonas Ferment Extract, Leuconostoc/Radish Root Ferment Filtrate, Magnesium Chloride, Phenoxyethanol, Cetyl Alcohol, Stearyl Alcohol, Trehalose, Glyceryl Stearate, Silanetriol Trehalose Ether, Mannitol, Phytosterols, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylic/Capric Triglyceride, Hydrogenated Lecithin, Polyglyceryl-10 Myristate, Polysorbate 20, Dimethyl Isosorbide, Sodium Benzoate, Potassium Sorbate, Caprylyl Glycol, Sodium Hydroxide, Laureth-12, Hydrolyzed Wheat Protein, Lecithin, Disodium Phosphate, Hydrolyzed Soy Protein, Carbomer, Dextran, Ethylhexylglycerin, Sodium Lactate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Sodium Phosphate, Xanthan Gum, Triethanolamine, Acrylates Copolymer
Water
Skin ConditioningGlycolic Acid
BufferingNeopentyl Glycol Dicaprylate/Dicaprate
EmollientGlycerin
HumectantCyclopentasiloxane
EmollientGlyceryl Stearate
EmollientPEG-100 Stearate
SurfactantStearic Acid
CleansingSodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingSodium Hydroxide
BufferingCaprylic/Capric Triglyceride
MaskingCetyl Alcohol
EmollientDimethicone
EmollientCetearyl Alcohol
EmollientIsohexadecane
EmollientSqualane
EmollientEthylhexyl Palmitate
EmollientPersea Gratissima Oil
Skin ConditioningOryza Sativa Bran Oil
EmollientButyrospermum Parkii Butter
Skin ConditioningSorbitol
HumectantPhenoxyethanol
PreservativeEucalyptus Globulus Leaf Oil
PerfumingSorbitan Stearate
EmulsifyingXanthan Gum
EmulsifyingPolysorbate 80
EmulsifyingPolysorbate 60
EmulsifyingPrunus Amygdalus Dulcis Oil
Skin ConditioningVegetable Oil
Skin ConditioningCaprylyl Glycol
EmollientMagnesium Aluminum Silicate
AbsorbentTocopheryl Acetate
AntioxidantSorbitan Oleate
EmulsifyingDipotassium Glycyrrhizate
HumectantEthylhexylglycerin
Skin ConditioningHexylene Glycol
EmulsifyingGlycine Soja Sterols
EmollientLinoleic Acid
CleansingPhospholipids
Skin ConditioningPolysorbate 20
EmulsifyingRetinol
Skin ConditioningLactic Acid
BufferingCetyl Palmitate
EmollientLaureth-23
CleansingCucumis Sativus Fruit Extract
EmollientLimonene
PerfumingTetrasodium Glutamate Diacetate
ChelatingHamamelis Virginiana Leaf Extract
Skin ConditioningCeramide NP
Skin ConditioningTrideceth-6 Phosphate
EmulsifyingPotassium Bitartrate
BufferingTitanium Dioxide
Cosmetic ColorantSodium Hyaluronate
HumectantTocopherol
AntioxidantBHT
AntioxidantPalmitic Acid
EmollientBHA
AntioxidantQuartz
AbrasiveAscorbic Acid
AntioxidantWater, Glycolic Acid, Neopentyl Glycol Dicaprylate/Dicaprate, Glycerin, Cyclopentasiloxane, Glyceryl Stearate, PEG-100 Stearate, Stearic Acid, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium Hydroxide, Caprylic/Capric Triglyceride, Cetyl Alcohol, Dimethicone, Cetearyl Alcohol, Isohexadecane, Squalane, Ethylhexyl Palmitate, Persea Gratissima Oil, Oryza Sativa Bran Oil, Butyrospermum Parkii Butter, Sorbitol, Phenoxyethanol, Eucalyptus Globulus Leaf Oil, Sorbitan Stearate, Xanthan Gum, Polysorbate 80, Polysorbate 60, Prunus Amygdalus Dulcis Oil, Vegetable Oil, Caprylyl Glycol, Magnesium Aluminum Silicate, Tocopheryl Acetate, Sorbitan Oleate, Dipotassium Glycyrrhizate, Ethylhexylglycerin, Hexylene Glycol, Glycine Soja Sterols, Linoleic Acid, Phospholipids, Polysorbate 20, Retinol, Lactic Acid, Cetyl Palmitate, Laureth-23, Cucumis Sativus Fruit Extract, Limonene, Tetrasodium Glutamate Diacetate, Hamamelis Virginiana Leaf Extract, Ceramide NP, Trideceth-6 Phosphate, Potassium Bitartrate, Titanium Dioxide, Sodium Hyaluronate, Tocopherol, BHT, Palmitic Acid, BHA, Quartz, Ascorbic Acid
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolCetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
Its main roles are:
Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.
The FDA allows products labeled "alcohol-free" to have fatty alcohols.
This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.
Learn more about Cetyl AlcoholDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinGlyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearatePhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolPolysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.
It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.
The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.
Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).
True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.
Because it is derived from lauric acid, it may not be fungal acne safe.
Learn more about Polysorbate 20Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideSqualane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Learn more about SqualaneTocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum