Loved

Acetyl Octapeptide-3

Explained

Acetyl Octapeptide-3 is a synthetic peptide also commonly known as SNAP-8. It is a lab-made peptide often marketed as a gentler, topical alternative to Botox.

It works by mimicking part of a protein involved in muscle contractions, which may help relax facial tension and reduce the appearance of fine lines (mostly around the eyes and forehead).

It’s considered a “next-gen” version of Argireline (Acetyl Hexapeptide-8), an older peptide with more research behind it that also supports collagen production.

SNAP-8 showed slightly better results than Argireline in one small manufacturer-funded study, but there’s limited independent research. Plus, most tests use concentrations higher than what’s typically found in skincare products.

This ingredient might offer a subtle smoothing effect but it won't don’t deliver the dramatic results of actual Botox injections.

Think of it more like a supporting actor in your skincare lineup.

See all 265 products with Acetyl Octapeptide-3

Users who like it
99%
Users who avoid it
1%

What it does

Humectant A substance that promotes retention of moisture.
Skin Conditioning To hydrate and soften skin

Prevalence

Less common Percentage of products that contain it
0.3%
Top categories
Treatments
Moisturizers
Eye Care
Position Predominant list placement
Bottom 25%

References

CosIng Data

CosIng ID 82188
INCI Name ACETYL OCTAPEPTIDE-3
EC #  -
All Functions Humectant, Skin Conditioning