Versus

Shiseido Vital Perfection LiftDefine Radiance Serum Versus MEDI-PEEL Peptide 9 Volume And Tension Tox Cream

Serum
General Moisturizer
Japanese Brand Japan
Korean Brand South Korea

Updated on August 29, 2024

Overview

What they are

These products are both reef safe . They have a total of 8 ingredients in common

Cool Features

They both contain Vitamin E

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing and better texture

Free From

They both do not contain any parabens or sulfates

What's Inside

They both contain fragrances and silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Vital Perfection LiftDefine Radiance Serum

Water

Skin Conditioning

Dipropylene Glycol

Masking

Dimethicone

Emollient
1 / 0 Silicon Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Behenyl Alcohol

Emollient
Fatty Alcohol Icon

Maltitol

Humectant

Triethylhexanoin

Masking

Potassium Methoxysalicylate

Bleaching

Polyvinyl Alcohol

PEG/PPG-14/7 Dimethyl Ether

Skin Conditioning

Phenoxyethanol

Preservative
Preservative Icon

Trimethylsiloxysilicate

Emollient
Silicon Icon

Batyl Alcohol

Emollient

Behenic Acid

Cleansing
0 / 0 Not safe for Fungal Acne Icon

PEG-60 Glyceryl Isostearate

Not safe for Fungal Acne Icon

PEG-10 Dimethicone

Skin Conditioning
Silicon Icon

Parfum

Masking
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Phytosteryl/Octyldodecyl Lauroyl Glutamate

Skin Conditioning

Disodium EDTA

Myristyl Myristate

Emollient
0-5 / 2 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Rosa Damascena Flower Water

Masking

Potassium Hydroxide

Buffering

Sodium Citrate

Buffering

2-O-Ethyl Ascorbic Acid

Skin Conditioning
Vitamin C IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Alcohol

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon

Caffeine

Skin Conditioning

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Lavandula Angustifolia Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen Icon

Sodium Metaphosphate

Buffering

PPG-3 Dipivalate

Skin Conditioning

Limonene

Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Hexyl Cinnamal

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Linalool

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Glucosamine Hcl

Citronellol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Lilium Candidum Bulb Extract

Skin Conditioning

Sodium Metabisulfite

Antioxidant
Antioxidant IconPreservative Icon

Angelica Acutiloba Root Extract

Skin Conditioning

Angelica Keiskei Leaf/Stem Extract

Skin Conditioning

Olea Europaea Leaf Extract

Perfuming
Fragrance Icon

Lamium Album Flower/Leaf/Stem Extract

Skin Conditioning

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Inositol

Humectant

Carthamus Tinctorius Flower Extract

Skin Conditioning

CI 77492

Cosmetic Colorant

Ziziphus Jujuba Fruit Extract

Skin Conditioning

CI 77491

Cosmetic Colorant

Rosmarinus Officinalis Leaf Extract

Antimicrobial

Cellulose

Absorbent

Nasturtium Officinale Leaf/Stem Extract

Skin Conditioning

Cinnamomum Cassia Bark Extract

Masking
May worsen Eczema Icon

Bupleurum Falcatum Root Extract

Skin Conditioning
Peptide 9 Volume And Tension Tox Cream

Water

Skin Conditioning

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Caprylic/Capric Triglyceride

Masking

Cetyl Ethylhexanoate

Emollient

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Stearic Acid

Cleansing
2-3 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Dimethicone

Emollient
1 / 0 Silicon Icon

1,2-Hexanediol

Skin Conditioning

Sorbitan Stearate

Emulsifying
0 / 1 Not safe for Fungal Acne Icon

Sorbitan Sesquioleate

Emulsifying
0-1 / 0 Bad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Microcrystalline Wax

Emulsion Stabilising
Not safe for Fungal Acne Icon

Beeswax

Emulsion Stabilising
0-2 / 0 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Isopentyldiol

Humectant

Betaine

Humectant
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Hydroxypropyltrimonium Hyaluronate

Sodium Acetylated Hyaluronate

Humectant
Hyaluronic Acid Icon

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Sodium Hyaluronate Crosspolymer

Humectant
Hyaluronic Acid Icon

Hydrolyzed Sodium Hyaluronate

Skin Conditioning

Potassium Hyaluronate

Skin Conditioning

Leontopodium Alpinum Callus Culture Extract

Antioxidant
Antioxidant Icon

Leontopodium Alpinum Root Extract

Skin Conditioning

Centella Asiatica Extract

Cleansing
Helps reduce Skin Redness IconHelps reduce irritation Icon

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Polygonum Cuspidatum Root Extract

Antioxidant
Antioxidant Icon

Scutellaria Baicalensis Root Extract

Astringent

Chamomilla Recutita Flower Extract

Masking
Helps reduce Skin Redness IconHelps reduce irritation Icon

Glycyrrhiza Glabra Root Extract

Bleaching
Good for Dark Spots Icon

Rosmarinus Officinalis Flower Extract

Antioxidant
Antioxidant IconFragrance Icon

Aloe Barbadensis Leaf Extract

Emollient
Helps reduce Skin Redness IconHelps reduce irritation Icon

Melia Azadirachta Flower Extract

Skin Conditioning

Melia Azadirachta Leaf Extract

Skin Conditioning

Ocimum Sanctum Leaf Extract

Skin Conditioning

Coccinia Indica Fruit Extract

Skin Conditioning

Royal Jelly Extract

Skin Conditioning
Good for Scar Healing Icon

Cladosiphon Okamuranus Extract

Skin Conditioning

Ginkgo Biloba Leaf Extract

Skin Conditioning

Chondrus Crispus Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Anemarrhena Asphodeloides Root Extract

Skin Conditioning

Collagen Extract

Skin Conditioning
Helps with Anti-Aging Icon

Collagen Amino Acids

Moisturising
Helps with Anti-Aging Icon

Hydrolyzed Collagen

Emollient
Helps hydrate Dry Skin IconHelps with Anti-Aging Icon

Collagen

Moisturising
Helps with Anti-Aging Icon

Hydrolyzed Elastin

Emollient

Astaxanthin

Skin Conditioning

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Fructan

Skin Conditioning

Hydrogenated Polyisobutene

Emollient
1 / 2

Dipotassium Glycyrrhizate

Humectant
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Adenosine

Skin Conditioning
Good for Minimizing Pores IconGood for Scar Healing Icon

Arginine

Masking
Good for Scar Healing IconNot safe for Fungal Acne Icon

Glycine

Buffering
Helps hydrate Dry Skin Icon

Serine

Masking

Glutamic Acid

Humectant

Aspartic Acid

Masking

Leucine

Skin Conditioning

Threonine

Proline

Skin Conditioning

Isoleucine

Skin Conditioning

Histidine

Humectant

Methionine

Skin Conditioning

Cysteine

Antioxidant
Antioxidant Icon

Copper Tripeptide-1

Skin Conditioning
Peptide IconGood for Skin Texture IconHelps with Anti-Aging Icon

Tripeptide-1

Skin Conditioning
Peptide IconHelps with Anti-Aging Icon

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps with Anti-Aging Icon

Nonapeptide-1

Skin Conditioning
Peptide Icon

Acetyl Octapeptide-3

Humectant
Peptide Icon

Palmitoyl Pentapeptide-4

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Hexapeptide-9

Skin Conditioning
Peptide Icon

Palmitoyl Tetrapeptide-7

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Palmitoyl Tripeptide-1

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Carbomer

Emulsion Stabilising
1 / 0

Hydrogenated Lecithin

Emulsifying

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

PEG-100 Stearate

0 / 0 Not safe for Fungal Acne Icon

Gold

Cosmetic Colorant

Diamond Powder

Abrasive
Exfoliant Icon

Ethylhexylglycerin

Skin Conditioning

Pentylene Glycol

Skin Conditioning

Hydroxyacetophenone

Antioxidant
Antioxidant Icon

Caprylyl Glycol

Emollient

Disodium EDTA

Parfum

Masking
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Water, Butylene Glycol, Caprylic/Capric Triglyceride, Cetyl Ethylhexanoate, Glycerin, Cetearyl Alcohol, Glyceryl Stearate, Niacinamide, Stearic Acid, Dimethicone, 1,2-Hexanediol, Sorbitan Stearate, Sorbitan Sesquioleate, Microcrystalline Wax, Beeswax, Isopentyldiol, Betaine, Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Acetylated Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Leontopodium Alpinum Callus Culture Extract, Leontopodium Alpinum Root Extract, Centella Asiatica Extract, Camellia Sinensis Leaf Extract, Polygonum Cuspidatum Root Extract, Scutellaria Baicalensis Root Extract, Chamomilla Recutita Flower Extract, Glycyrrhiza Glabra Root Extract, Rosmarinus Officinalis Flower Extract, Aloe Barbadensis Leaf Extract, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Ocimum Sanctum Leaf Extract, Coccinia Indica Fruit Extract, Royal Jelly Extract, Cladosiphon Okamuranus Extract, Ginkgo Biloba Leaf Extract, Chondrus Crispus Extract, Anemarrhena Asphodeloides Root Extract, Collagen Extract, Collagen Amino Acids, Hydrolyzed Collagen, Collagen, Hydrolyzed Elastin, Astaxanthin, Tocopherol, Fructan, Hydrogenated Polyisobutene, Dipotassium Glycyrrhizate, Adenosine, Arginine, Glycine, Serine, Glutamic Acid, Aspartic Acid, Leucine, Threonine, Proline, Isoleucine, Histidine, Methionine, Cysteine, Copper Tripeptide-1, Tripeptide-1, Acetyl Hexapeptide-8, Nonapeptide-1, Acetyl Octapeptide-3, Palmitoyl Pentapeptide-4, Hexapeptide-9, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Carbomer, Hydrogenated Lecithin, Polysorbate 20, PEG-100 Stearate, Gold, Diamond Powder, Ethylhexylglycerin, Pentylene Glycol, Hydroxyacetophenone, Caprylyl Glycol, Disodium EDTA, Parfum

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Emollient, Skin Conditioning, Skin Protecting

Dimethicone is a type of synthetic silicone created from natural materials such as quartz.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Learn more about Dimethicone
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.
  • It has mild preservative properties.

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Masking, Perfuming

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Learn more about Parfum

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Antioxidant, Masking, Skin Conditioning

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol
Antimicrobial, Antioxidant, Astringent

Camellia Sinensis Leaf Extract is derived from the leaves of the tea plant. Black tea, green tea, and oolong tea are all harvested from this plant.

This ingredient has many skin benefits:

This ingredient contains polyphenols, a strong antioxidant. Antioxidants help fight off molecules that damage skin cells.

On top of that, the antioxidants in green tea neutralize free-radicals from the sun. This gives the skin some extra UV protection, but should not replace sunscreen.

Many components of tea have anti-inflammatory properties.

Polyphenols and L-theanine help soothe the skin and reduce irritation. The caffeine in Camellia Sinensis Leaf Extract helps calm inflamed blood vessels.

Other compounds found in tea include: Vitamin Bs, linoleic acid, magnesium, calcium, iron, and zinc.

Research has shown both drinking Camellia Sinensis Leaf Tea and applying it to the skin can help boost skin elasticity and hydration. Studies also show using tea extract may reduce sebum, or oil, production.

Learn more about Camellia Sinensis Leaf Extract

When to use

8 Routines
63% use in am
38% use in pm
88% use every day
1 Routine
100% use in am
0% use in pm
100% use every day