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Neutrogena Hydro Boost Hydrating Serum Versus Shiseido Vital Perfection LiftDefine Radiance Serum

Serum
Serum
American Brand United States
Japanese Brand Japan

Overview

What they are

These products are both reef safe serums. They have a total of 6 ingredients in common

Suited For

They're both likely to be good for dry skin, brightening skin and sensitive skin

Free From

They both do not contain any parabens or sulfates

What's Inside

They both contain harsh alcohols, common allergens, fragrances and silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Benefits

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Hydro Boost Hydrating Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon
SiliconSilicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Neopentyl Glycol Diheptanoate Emollient, Skin Conditioning

We don't have a description for Neopentyl Glycol Diheptanoate.

Aluminum Starch Octenylsuccinate Absorbent

Aluminum Starch Octenylsuccinate is a synthetic powder used as an absorbent, thickener, and anti-caking agent.

Disliked Full details ->
Isododecane Emollient, Solvent

Isododecane is a fragrance, emollient, and solvent.

Disliked Full details ->
Dimethiconol Emollient, Moisturising

Dimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.

Disliked Full details ->
Ammonium Polyacryloyldimethyl Taurate Emulsion Stabilising

Ammonium Polyacryloyldimethyl Taurate is a polymer made from ammonium salts. It helps add stability and texture to a product.

Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Benzyl Alcohol Perfuming, Preservative, Solvent
Alcohol IconFragrance IconPreservative IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon
AlcoholAlcohol Icon FragranceFragrance Icon PreservativePreservative Icon 6 Concerns

Benzyl Alcohol is most commonly used as a preservative. It also has a subtle, sweet smell. Small amounts of Benzyl Alcohol is not irritating and safe to use in skincare products. Most Benzyl Alcohol is derived from fruits such as apricots.

Very Disliked Full details ->
Sodium Lactate Buffering, Humectant

Sodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and used to adjust the pH of a product.

Cetearyl Olivate
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Cetearyl Olivate is an emulsifier and texture enhancer. It is derived from the fatty acids of olive oil and Cetearyl alcohol, and is biodegradable.

Disliked Full details ->
Bisabolol Masking, Skin Conditioning, Soothing
Helps reduce irritation Icon
Helps reduce irritationHelps reduce irritation Icon

Bisabolol is pimarily used to add fragrance to a product. However, it is also famous for helping soothe skin.

Chlorphenesin Antimicrobial, Preservative
Preservative Icon
PreservativePreservative Icon

Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.

Disliked Full details ->
Sorbitan Olivate Emulsifying
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.

Very Disliked Full details ->
Sodium PCA Humectant, Skin Conditioning
0 / 0

Sodium PCA is the sodium salt of pyroglutamic acid and is naturally occurring on human skin.

0 Com. / 0 Irr.
Parfum Masking, Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon
FragranceFragrance Icon 2 Concerns

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Very Disliked Full details ->
Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Acrylates Copolymer

Acrylates Copolymer is used as a film-forming agent and texture enhancer.

Disliked Full details ->
Sorbitol Humectant, Masking, Skin Conditioning
0 / 0 Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Sorbitol is a sugar alcohol. It is a hydrating and moisturizing agent created from the reduction process of glucose.

0 Com. / 0 Irr.
Chondrus Crispus Extract Skin Conditioning
Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Chondrus Crispus Extract comes from a red algae native to the northern Atlantic coasts of Europe and North America.

Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Proline Skin Conditioning

Proline is an amino-acid. It helps moisturize the skin and plays an important role in creating proteins.

Portulaca Oleracea Extract Skin Conditioning

Portulaca Oleracea Extract is an extract of the whole plant of the Purslane, Portulaca oleracea L., Portulacaceae. It has anti-inflammatory, antioxidant, and hydrating properties.

Propylene Glycol Humectant, Skin Conditioning, Solvent
0 / 0 May worsen Eczema Icon
May worsen EczemaMay worsen Eczema Icon

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

0 Com. / 0 Irr.
Disliked Full details ->
Citric Acid Buffering, Masking
AHA IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
AHAAHA Icon 4 Benefits 2 Concerns

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

Disliked Full details ->
Magnesium Aspartate Skin Conditioning

We don't have a description for Magnesium Aspartate.

Unknown Full details ->
Zinc Gluconate Skin Conditioning

We don't have a description for Zinc Gluconate.

Copper Gluconate Skin Conditioning, Skin Protecting

We don't have a description for Copper Gluconate.

Vital Perfection LiftDefine Radiance Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Dipropylene Glycol Masking, Solvent

Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.

Disliked Full details ->
Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon
SiliconSilicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Behenyl Alcohol Emollient, Emulsion Stabilising
Fatty Alcohol Icon
Fatty AlcoholFatty Alcohol Icon

A type of fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product. They are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as traditional alcohols.

Disliked Full details ->
Maltitol Humectant, Masking, Moisturising

We don't have a description for Maltitol.

Unknown Full details ->
Triethylhexanoin Masking, Skin Conditioning

Triethylhexanoin is created from glycerin and 2-ethylhexanoic acid. It is a solvent and emollient.

Potassium Methoxysalicylate Bleaching

We don't have a description for Potassium Methoxysalicylate.

Unknown Full details ->
Polyvinyl Alcohol

We don't have a description for Polyvinyl Alcohol.

Very Disliked Full details ->
Peg/Ppg-14/7 Dimethyl Ether Skin Conditioning

We don't have a description for Peg/Ppg-14/7 Dimethyl Ether.

Unknown Full details ->
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Trimethylsiloxysilicate Emollient, Skin Conditioning

This silicone is an emollient. Emollients create a thin film on the skin to prevent moisture from escaping.

Disliked Full details ->
Batyl Alcohol Emollient, Emulsion Stabilising, Skin Conditioning

We don't have a description for Batyl Alcohol.

Unknown Full details ->
Behenic Acid Cleansing, Emulsifying
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Behenic Acid is a fatty acid and has moisturizing properties.

0 Com. / 0 Irr.
Disliked Full details ->
Peg-60 Glyceryl Isostearate
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Peg-60 Glyceryl Isostearate isn't fungal acne safe.

Unknown Full details ->
Peg-10 Dimethicone Skin Conditioning
Silicon Icon
SiliconSilicon Icon

Peg-10 Dimethicone is silicone with conditioner and emulsifier properties. It mostly acts as an emollient in skincare and and humectant in haircare.

Very Disliked Full details ->
Parfum Masking, Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon
FragranceFragrance Icon 2 Concerns

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Very Disliked Full details ->
Phytosteryl/Octyldodecyl Lauroyl Glutamate Skin Conditioning

We don't have a description for Phytosteryl/Octyldodecyl Lauroyl Glutamate.

Unknown Full details ->
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Myristyl Myristate Emollient, Skin Conditioning
0-5 / 2 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
3 Concerns

Myristyl Myristate is created from the fatty acids of myristyl alcohol and myristic acid. In skincare, it is an emollient and texture enhancer.

0-5 Com. / 2 Irr.
Very Disliked Full details ->
Tocopheryl Acetate Antioxidant, Skin Conditioning
0 / 0 Vitamin E IconAntioxidant IconHelps brighten skin Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon Helps brighten skinHelps brighten skin Icon

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

0 Com. / 0 Irr.
Rosa Damascena Flower Water Masking, Skin Conditioning, Skin Protecting

Rosa Damascena Flower Water comes from the Damask rose. It is a dilluted version of the Rose Essential oil.

Potassium Hydroxide Buffering

Potassium hydroxide is commonly known as caustic potash. It is used to fix the pH of a product or as a cleaning agent in soap. In cleansers, it is used for the saponification of oils.

Very Disliked Full details ->
Sodium Citrate Buffering, Masking

Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.

2-O-Ethyl Ascorbic Acid Skin Conditioning
Vitamin C IconHelps reduce Skin Redness IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Dark Spots Icon
Vitamin CVitamin C Icon 4 Benefits

2-O-Ethyl Ascorbic Acid is a form of Vitamin C. It can help to reduce redness, improve skin texture, reduce the effects of aging, and reduce the visibility of dark spots.

Alcohol Antimicrobial, Astringent, Masking
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon
AlcoholAlcohol Icon 5 Concerns

Alcohol comes in many different forms. Different types of alcohol will have different effects on skin. This ingredient is usually an astringent alcohol.

Very Disliked Full details ->
Caffeine Skin Conditioning

Caffeine is most associated with coffee, tea, and cacao. In skincare, it helps with calming inflammation and anti-aging.

Citric Acid Buffering, Masking
AHA IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
AHAAHA Icon 4 Benefits 2 Concerns

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

Disliked Full details ->
Lavandula Angustifolia Oil Masking, Tonic
Oil IconEU Allergen Icon
OilOil Icon EU AllergenEU Allergen Icon

Lavandula Angustifolia Oil is more commonly known as lavender essential oil. Lavandula Angustifolia is known as the English Lavender and famous for creating purple fields in Provence, France.

Very Disliked Full details ->
Sodium Metaphosphate Buffering

We don't have a description for Sodium Metaphosphate.

Unknown Full details ->
Ppg-3 Dipivalate Skin Conditioning

We don't have a description for Ppg-3 Dipivalate.

Unknown Full details ->
Limonene Perfuming, Solvent
Fragrance Icon
FragranceFragrance Icon

Limonene is a fragrance that adds scent and taste to a formulation.

Very Disliked Full details ->
Hexyl Cinnamal Perfuming
Fragrance IconEU Allergen Icon
FragranceFragrance Icon EU AllergenEU Allergen Icon

Hexyl Cinnamal is a fragrance ingredient with a similar scent to jasmine. It can be naturally found in chamomile essential oil.

Very Disliked Full details ->
Linalool Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon
FragranceFragrance Icon 2 Concerns

Linalool is a fragrance and helps add scent to products. It's derived from common plants such as cinnamon, mint, citrus, and lavender.

Very Disliked Full details ->
Tocopherol Antioxidant, Masking, Skin Conditioning
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon 4 Benefits May cause irritationMay cause irritation Icon

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

0-3 Com. / 0-3 Irr.
Glucosamine Hcl

We don't have a description for Glucosamine Hcl.

Citronellol Perfuming
Fragrance IconEU Allergen Icon
FragranceFragrance Icon EU AllergenEU Allergen Icon

Citronellol is used to add fragrance/parfum to a product. It is often derived from plants such as roses. In fact, it can be found in many essential oils including geranium, lavender, neroli, and more. The scent of Citronellol is often described as "fresh, grassy, and citrus-like".

Very Disliked Full details ->
Lilium Candidum Bulb Extract Skin Conditioning

We don't have a description for Lilium Candidum Bulb Extract.

Unknown Full details ->
Sodium Metabisulfite Antioxidant, Preservative
Antioxidant IconPreservative Icon
AntioxidantAntioxidant Icon PreservativePreservative Icon

Sodium Metabisulfite is an antioxidant and is a preservative.

Angelica Acutiloba Root Extract Skin Conditioning

We don't have a description for Angelica Acutiloba Root Extract.

Unknown Full details ->
Angelica Keiskei Leaf/Stem Extract Skin Conditioning

We don't have a description for Angelica Keiskei Leaf/Stem Extract.

Unknown Full details ->
Olea Europaea Leaf Extract Perfuming, Skin Conditioning
Fragrance Icon
FragranceFragrance Icon

Olea Europaea Leaf Extract is a fragrance.

Lamium Album Flower/Leaf/Stem Extract Skin Conditioning

We don't have a description for Lamium Album Flower/Leaf/Stem Extract.

Unknown Full details ->
Camellia Sinensis Leaf Extract Antimicrobial, Antioxidant, Astringent
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconHelps fight Acne Icon
AntioxidantAntioxidant Icon 5 Benefits

Camellia Sinensis Leaf Extract is derived from the leaves of the tea plant. Black tea, green tea, and oolong tea are all harvested from this plant.

Inositol Humectant

Inositol is a sugar alcohol naturally found in the human body. Our bodies use this ingredient in the process of growing new cells.

Carthamus Tinctorius Flower Extract Skin Conditioning

We don't have a description for Carthamus Tinctorius Flower Extract.

Unknown Full details ->
CI 77492 Cosmetic Colorant

Ci 77492 is also hydrated iron III oxide. It's sole purpose is to give a yellow hue to products.

Ziziphus Jujuba Leaf Extract Skin Conditioning

We don't have a description for Ziziphus Jujuba Leaf Extract.

Unknown Full details ->
CI 77491 Cosmetic Colorant

Ci 77491 is also hydrated iron III oxide. It's sole purpose is to give a red/pink hue to products.

Rosmarinus Officinalis Leaf Extract Antimicrobial, Masking, Skin Conditioning

Rosmarinus Officinalis Leaf Extract comes from rosemary. Rosemary is native to the Mediterranean.

Cellulose Absorbent

Cellulose is the main component of plant cell walls. It is used as an emulsifier, absorbent, and texture enhancer.

Nasturtium Officinale Leaf/Stem Extract Skin Conditioning

We don't have a description for Nasturtium Officinale Leaf/Stem Extract.

Unknown Full details ->
Cinnamomum Cassia Bark Extract Masking

We don't have a description for Cinnamomum Cassia Bark Extract.

Disliked Full details ->
Bupleurum Falcatum Root Extract Skin Conditioning

We don't have a description for Bupleurum Falcatum Root Extract.

Unknown Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Skin Conditioning, Skin Protecting
Very Disliked

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

Dimethicone has been found increase absorption in skin, boosting the benefits of other ingredients. While there is concern for the safety of dimethicone, the levels used in skincare are safe for use.

Humectant, Masking, Skin Conditioning
Mixed

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.

Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.

Masking, Perfuming
Very Disliked

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.

In the US, the alternative name for parfum is 'fragrance'.

The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Learn more about Parfum
Buffering, Masking
Disliked

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.

If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.

Read more about some other popular AHA's here:

Learn more about Citric Acid

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

Hydro Boost Hydrating Serum
14
3
12
1
liked
mixed
disliked
not rated
Vital Perfection LiftDefine Radiance Serum
11
8
20
16
liked
mixed
disliked
not rated

When to use

57 Routines
54% use in am
46% use in pm
95% use every day
When to use See routines that use it ->
5 Routines
60% use in am
40% use in pm
80% use every day