Versus

SKIN1004 Madagascar Centella Probio-Cica Intensive Ampoule Versus Meditherapy Retinal Skin Booster Serum

Ampoule
Serum
Korean Brand South Korea
Korean Brand South Korea

Updated on January 15, 2025

Overview

What they are

These products are both reef safe . They have a total of 20 ingredients in common

Cool Features

They both contain ceramides, hyaluronic acid and niacinamide

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, common allergens, parabens or sulfates

What's Inside

They both contain oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Madagascar Centella Probio-Cica Intensive Ampoule

Centella Asiatica Extract

Cleansing
Helps reduce Skin Redness IconHelps reduce irritation Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Water

Skin Conditioning

Propanediol

Solvent
Retinal Skin Booster Serum

Water

Skin Conditioning

Methylpropanediol

Solvent

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Caprylic/Capric Triglyceride

Masking

1,2-Hexanediol

Skin Conditioning

Propanediol

Solvent

Polyglycerin-3

Humectant

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Phenyl Trimethicone

Skin Conditioning
Silicon Icon

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Sodium Acrylic Acid/Ma Copolymer

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Antioxidant
Antioxidant Icon

Xanthan Gum

Emulsifying

Macadamia Ternifolia Seed Oil

Emollient
Oil IconNot safe for Fungal Acne Icon

Hydrogenated Lecithin

Emulsifying

Ethylhexylglycerin

Skin Conditioning

Adenosine

Skin Conditioning
Good for Minimizing Pores IconGood for Scar Healing Icon

Carbomer

Emulsion Stabilising
1 / 0

Disodium EDTA

Tromethamine

Buffering

Polyglyceryl-10 Laurate

Skin Conditioning
Not safe for Fungal Acne Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Brassica Campestris Sterols

Emollient
Not safe for Fungal Acne Icon

Retinal

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Ascorbyl Tetraisopalmitate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconNot safe for Fungal Acne Icon

Potentilla Anserina Extract

Skin Conditioning

Caprylyl Glycol

Emollient

Aluminum/Magnesium Hydroxide Stearate

Emulsion Stabilising

Polyquaternium-51

Skin Conditioning

Cynara Scolymus Leaf Extract

Skin Conditioning

Avena Sativa Kernel Extract

Abrasive
Exfoliant IconAntioxidant IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Beta-Glucan

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Potassium Cetyl Phosphate

Emulsifying

Camellia Sinensis Leaf Water

Masking
Fragrance Icon

Piper Methysticum Leaf/Root/Stem Extract

Skin Conditioning

Sodium Ascorbyl Phosphate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Centella Asiatica Extract

Cleansing
Helps reduce Skin Redness IconHelps reduce irritation Icon

Ficus Carica Fruit Extract

Humectant

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Centella Asiatica Leaf Extract

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon

Saccharomyces Ferment

Skin Conditioning
Not safe for Fungal Acne Icon

Centella Asiatica Root Extract

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon

Canola Oil

Emollient
Oil IconNot safe for Fungal Acne Icon

Myristyl Alcohol

Emollient
2 / 4 Fatty Alcohol Icon

PCA

Humectant

Acetyl Hexapeptide-1

Skin Conditioning
Peptide Icon

Asiaticoside

Antioxidant
Antioxidant IconGood for Scar Healing Icon

Madecassoside

Antioxidant
Antioxidant IconHelps reduce irritation IconHelps with Anti-Aging Icon

Daucus Carota Sativa Seed Oil

Emollient
Oil Icon

Bifida Ferment Lysate

Skin Conditioning
Helps hydrate Dry Skin Icon

Lactobionic Acid

Buffering
PHA IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Daucus Carota Sativa Root Extract

Skin Conditioning

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Beta-Carotene

Skin Conditioning

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Polygonum Cuspidatum Root Extract

Antioxidant
Antioxidant Icon

Sucrose Distearate

Emollient
0 / 2 Not safe for Fungal Acne Icon

Hydroxypropyl Cyclodextrin

Masking

Madecassic Acid

Skin Conditioning
Helps reduce irritation IconHelps with Anti-Aging Icon

Asiatic Acid

Skin Conditioning

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Cleansing, Skin Conditioning, Smoothing

Centella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.

Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.

Studies show the compounds in centella help with:

The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.

Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.

Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Learn more about Centella Asiatica Extract
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.
  • It has mild preservative properties.

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride
Smoothing

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.

This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Skin Conditioning

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Learn more about Panthenol
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum

Macadamia Ternifolia Seed Oil is the fixed oil obtained from Macadamia nut.

Macadamia seed oil is rich in fatty acids, including oleic acid (45-75%), palmitoleic acid (7-33%), and palmitic acid (6-12%). They also contain various B vitamins, iron, and magnesium.

Palmitoleic acid has been shown to help soothe inflammation and promote wound healing. It is also naturally found in the fat of our skin.

Macadamia seed oil may not be malassezia folliculitis, or fungal-acne, safe.

Learn more about Macadamia Ternifolia Seed Oil
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Skin Conditioning

Ceramide NP is a type of ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here: Ceramide AP Ceramide EOP

Learn more about Ceramide NP
Skin Conditioning

Madecassic Acid is a major component of Centella Asiatica Extract. It has anti-inflammatory and antioxidant properties.

It is a triterpenoid, meaning it naturally acts as an antioxidant. Antioxidants protect your skin against damage from environmental factors such as pollution and UV.

Studies show Madecassic Acid helps soothe the skin due to its ability to block inflammation pathways.

Learn more about Madecassic Acid
Antioxidant, Skin Conditioning

Asiaticoside comes from the super popular skin-soothing ingredient, Centella asiatica. It is one of four active compounds found in the extract of Centella Asiatica.

Asiaticoside is an antioxidant and helps with wound healing. It has been shown to increase antioxidant activity during the wound healing process.

Skin Conditioning, Stabilising

Asiatic Acid is a major component of Centella Asiatica Extract. It has wound-healing, anti-inflammatory, and antioxidant properties.

Studies show Asiatic Acid is able to block the pathway for skin inflammation receptors, helping to soothe skin.

As an antioxidant, asiatic acid helps protect our skin against damaging environmental factors.

Learn more about Asiatic Acid
Emollient, Emulsifying, Skin Conditioning

Sucrose Distearate is made up of the sucrose (sugar) esthers of stearic acid. It is an emollient and emulsifier.

This ingredient may not be Malassezia folliculitis, or fungal-acne safe.

When to use

932 Routines
37% use in am
63% use in pm
89% use every day
When to use See routines that use it ->
23 Routines
9% use in am
87% use in pm
83% use every day

Reviews

Here's what our community thinks

SKIN1004 Madagascar Centella Probio-Cica Intensive Ampoule 44 ingredients

4.2 /5
from 17 ratings
Works Well (13) Hydrating (11) Great Value (9)
Cheeks's avatar

Cheeks

4 months ago
Review

This has been my favourite barrier supporting ampoule/serum to date! My skin soaks this up I use this both am and pm (with a little more in the pm). I have dry, sensitive and rosacea prone skin and this hasn’t ever aggravated anything, no reactions, blends effortlessly and just gives me a hydrated glowy look! Love it! It’s a creamy ampoule but not super thick and just melts into the skin. It’s so Show more

#great value
#hydrating
#light
#absorbs well
m.evstigneev's avatar

M. Evstigneev

4 months ago
Review

Lovely texture and a good value. Unfortunately, my skin reacted violently to it, it was very irritating, especially around my cheekbones. It is ironic because it’s marketed as soothing and calming for sensitive skin, and I’m not even that sensitive. My suspicion is that I can’t tolerate fermented ingredients because it happened with some other fermented products as well.

#great value
#irritating
#light
#no scent

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