Versus

P.Calm Retinolagen Ampoule Versus Meditherapy Retinal Skin Booster Serum

Ampoule
Serum
Korean Brand South Korea
Korean Brand South Korea

Updated on January 06, 2025

Overview

What they are

These products are both reef safe . They have a total of 22 ingredients in common

Cool Features

They both contain exfoliants, niacinamide, PHA and retinoid

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, parabens or sulfates

What's Inside

They both contain fragrances, oils and silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Retinolagen Ampoule

Water

Skin Conditioning

Gluconolactone

Skin Conditioning
PHA IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Methylpropanediol

Solvent

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Propanediol

Solvent
Helps hydrate Dry Skin Icon

Polyglycerin-3

Humectant
Helps hydrate Dry Skin Icon

Tromethamine

Buffering

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Soluble Collagen

Humectant
Helps hydrate Dry Skin IconHelps with Anti-Aging Icon

C12-14 Alketh-12

Emulsifying

Dimethicone

Emollient
1 / 0 Silicon Icon

Methyl Gluceth-20

Humectant
Helps hydrate Dry Skin Icon

Methyl Gluceth-10

Emulsifying

Glycereth-26

Humectant
0 / 0 Helps hydrate Dry Skin Icon

Coptis Japonica Extract

Antimicrobial

Hydroxyethylcellulose

Emulsion Stabilising

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Sodium Polyacryloyldimethyl Taurate

Emulsion Stabilising

Lecithin

Emollient
Helps hydrate Dry Skin Icon

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Eclipta Prostrata Extract

Skin Conditioning

Coccinia Indica Fruit Extract

Skin Conditioning

Succinic Acid

Buffering

Sodium Polyacrylate

Absorbent
Helps hydrate Dry Skin Icon

Ethylhexylglycerin

Skin Conditioning

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Adenosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing Icon

Viola Odorata Flower/Leaf Extract

Masking

Hedera Helix Leaf/Stem Extract

Antimicrobial

Pogostemon Cablin Leaf Oil

Masking
Oil IconMay cause irritation IconEU Allergen Icon

Lithospermum Erythrorhizon Root Extract

Skin Conditioning

Mentha Viridis Extract

Masking

Ribes Nigrum Fruit Extract

Astringent
Fragrance Icon

Punica Granatum Fruit Extract

Antioxidant
Antioxidant IconHelps reduce irritation IconGood for Dark Spots Icon

Lactobacillus Ferment

Skin Conditioning

Cymbopogon Martini Oil

Masking
Oil Icon

Lavandula Hybrida Oil

Emollient
Oil Icon

Rosmarinus Officinalis Leaf Oil

Masking
Oil Icon

Gleditsia Triacanthos Seed Extract

Glyceryl Caprylate

Emollient

Polylactic Acid

Abrasive
Exfoliant Icon

Macadamia Ternifolia Seed Oil

Emollient
Oil IconNot safe for Fungal Acne Icon

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin Icon

Polyglyceryl-10 Laurate

Skin Conditioning
Not safe for Fungal Acne Icon

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Silica

Abrasive
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon

Retinal

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Brassica Campestris Sterols

Emollient
Not safe for Fungal Acne Icon

Ceteth-5

Emulsifying

Ceteth-3

Emulsifying

Potassium Cetyl Phosphate

Emulsifying

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Antioxidant
Antioxidant Icon

Bakuchiol

Antimicrobial
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging IconGood for Dark Spots IconHelps brighten skin Icon

Disodium EDTA

Retinal Skin Booster Serum

Water

Skin Conditioning

Methylpropanediol

Solvent

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Propanediol

Solvent
Helps hydrate Dry Skin Icon

Polyglycerin-3

Humectant
Helps hydrate Dry Skin Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Phenyl Trimethicone

Skin Conditioning
Silicon Icon

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Sodium Acrylic Acid/Ma Copolymer

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Antioxidant
Antioxidant Icon

Xanthan Gum

Emulsifying

Macadamia Ternifolia Seed Oil

Emollient
Oil IconNot safe for Fungal Acne Icon

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin Icon

Ethylhexylglycerin

Skin Conditioning

Adenosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing Icon

Carbomer

Emulsion Stabilising
1 / 0

Disodium EDTA

Tromethamine

Buffering

Polyglyceryl-10 Laurate

Skin Conditioning
Not safe for Fungal Acne Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Brassica Campestris Sterols

Emollient
Not safe for Fungal Acne Icon

Retinal

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Ascorbyl Tetraisopalmitate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Dark Spots IconNot safe for Fungal Acne Icon

Potentilla Anserina Extract

Skin Conditioning

Caprylyl Glycol

Emollient

Aluminum/Magnesium Hydroxide Stearate

Emulsion Stabilising

Polyquaternium-51

Skin Conditioning
Helps hydrate Dry Skin Icon

Cynara Scolymus Leaf Extract

Skin Conditioning

Avena Sativa Kernel Extract

Abrasive
Exfoliant IconAntioxidant IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Beta-Glucan

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging IconGood for Scar Healing Icon

Potassium Cetyl Phosphate

Emulsifying

Camellia Sinensis Leaf Water

Masking
Fragrance Icon

Piper Methysticum Leaf/Root/Stem Extract

Skin Conditioning

Sodium Ascorbyl Phosphate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Centella Asiatica Extract

Cleansing
Helps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ficus Carica Fruit Extract

Humectant
Helps hydrate Dry Skin Icon

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Centella Asiatica Leaf Extract

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

Saccharomyces Ferment

Skin Conditioning
Helps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Centella Asiatica Root Extract

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon

Canola Oil

Emollient
Oil IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Myristyl Alcohol

Emollient
2 / 4 Fatty Alcohol Icon

PCA

Humectant
Helps hydrate Dry Skin Icon

Acetyl Hexapeptide-1

Skin Conditioning
Peptide Icon

Asiaticoside

Antioxidant
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Madecassoside

Antioxidant
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

Daucus Carota Sativa Seed Oil

Emollient
Oil IconHelps hydrate Dry Skin IconHelps reduce irritation Icon

Bifida Ferment Lysate

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Lactobionic Acid

Buffering
PHA IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Daucus Carota Sativa Root Extract

Skin Conditioning
Helps reduce irritation Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Beta-Carotene

Skin Conditioning

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Polygonum Cuspidatum Root Extract

Antioxidant
Antioxidant Icon

Sucrose Distearate

Emollient
0 / 2 Not safe for Fungal Acne Icon

Hydroxypropyl Cyclodextrin

Masking

Madecassic Acid

Skin Conditioning
Helps reduce irritation IconHelps with Anti-Aging Icon

Asiatic Acid

Skin Conditioning

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

Methylpropanediol is a synthetic solvent and humectant.

As a solvent, it helps dissolve other ingredients, helping to evenly distribute ingredients throughout the product. This ingredient has also been shown to have antimicrobial properties which makes it a preservative booster.

Methylpropanediol is able to add a bit of moisture to the skin. It also helps other ingredients be better absorbed into the skin, such as salicylic acid.

Learn more about Methylpropanediol
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Humectant

Polyglycerin-3 is a 3-unit glycerin polymer.

Like glycerin, this ingredient is a humectant. Humectants help hydrate your skin by drawing water to it.

Having moisturized skin helps improve the skin barrier. Your skin barrier helps protect against irritants and bacteria.

Learn more about Polyglycerin-3
Buffering, Masking

Tromethamine helps balance the pH and improve the texture of a product. It is synthetically created.

As an emulsifier, Tromethamine prevents oil and water ingredients from separating. This helps stabilize the product and elongate a product's shelf life. Tromethamine also makes a product thicker.

Tromethamine helps balance the pH level of a product. Normal pH level of skin is slightly acidic (~4.75-5.5). The acidity of our skin is maintained by our glands and skin biome. Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.

Oral Tromethanmine is an anti-inflammatory drug but plays the role of masking, adding fragrance, and/or balancing pH in skincare.

1,3-Propanediol, 2-amino-2-(hydroxymethyl)-

Learn more about Tromethamine
Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride

Ammonium Acryloyldimethyltaurate/Vp Copolymer (let's call it AAVC for short) is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.

AAVC is able to increase the consistency and viscosity of products due to its large molecule size. It also prevents ingredients from separating.

Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine

Macadamia Ternifolia Seed Oil is the fixed oil obtained from Macadamia nut.

Macadamia seed oil is rich in fatty acids, including oleic acid (45-75%), palmitoleic acid (7-33%), and palmitic acid (6-12%). They also contain various B vitamins, iron, and magnesium.

Palmitoleic acid has been shown to help soothe inflammation and promote wound healing. It is also naturally found in the fat of our skin.

Macadamia seed oil may not be malassezia folliculitis, or fungal-acne, safe.

Learn more about Macadamia Ternifolia Seed Oil
Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.

This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Skin Conditioning

Polyglyceryl-10 Laurate is an ester of lauric acid and Polyglycerin-10.

Polyglyceryl-10 Laurate is a cleansing agent and emulsifier. It helps gather dirt, oil, and other pollutants to be rinsed away. As an emulsifier, it helps prevent ingredients from separating, such as oil and water.

Polyglyceryl-10 Laurate may not be fungal acne safe.

Learn more about Polyglyceryl-10 Laurate
Emollient, Emulsifying, Skin Conditioning

Cholesterol is a class of organic molecules called lipids. It helps hydrate your skin and is essential to having a healthy skin barrier.

Our skin naturally contains cholesterol in the outermost layer. Besides cholesterol, it also contains ceramides and fatty acids. Cholesterol makes up about 1/4 of your skin's outer layer and barrier. Your skin barrier is responsible for keeping allergens and microbes out. Having a healthy skin barrier is also responsible for keeping your skin firm and plump.

Our bodies use cholestrol to create vitamin D, steroid hormones, and more.

Learn more about Cholesterol
Skin Conditioning

Retinal is a form of retinoid. Retinoids are the gold-standard class of anti-aging ingredients.

Retinal has many benefits as other retinoids: improve skin texture, reduce large pores, reduce the effects of aging, reduce the visibility of dark spots, heal scars, and fight acne.

Studies show retinal may work at a faster rate than retinol due to its structure.

All retinoids have to be converted into retinoic acid before starting to work. Some retinoids take several steps of conversion before binding. Retinal is only one step away, making it more potent.

Like other retinoids, retinal may be irritating. It is best to ease into using this ingredient frequently.

Using the 'ramp up' method, start by using retinol once a week. This gives your skin time to adjust and decrease irritation. Once you feel ready, you can slowly increase the frequency of retinol use.

Using retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

Learn more about Retinal
Emollient, Skin Conditioning

Brassica Campestris Sterols isn't fungal acne safe.

Potassium Cetyl Phosphate is the potassium salt of a mixture. This mixture consists of the esters from phosphoricacid and cetyl alcohol.

Potassium Cetyl Phosphate is an emulsifier and cleansing agent. Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating.

As a cleansing agent, Potassium Cetyl Phosphate helps gather oils, dirts, and pollutants from your skin. This makes it easier to rinse them away with water.

Learn more about Potassium Cetyl Phosphate

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate (long name, huh?) is a synthetic antioxidant.

It is used to help stabilize other antioxidants or prevent the color from changing in a product.

As an antioxidant, it helps fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Thus, antioxidants may reduce the signs of aging.

This ingredient is oil-soluble.

Learn more about Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA

When to use

5 Routines
20% use in am
80% use in pm
100% use every day
25 Routines
12% use in am
88% use in pm
84% use every day