Skinmade Star Retinal Super Skin Renewal Night Serum

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Isododecane's role as a solvent makes it a great texture enhancer. It spreads smoothly on skin and does not leave a sticky feeling behind. Isododecane also helps prevent color transfer in makeup products.

Isododecane is not absorbed into skin.

Manufacturers use the name Olivem 1000. This ingredient has been found to preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria. This ingredient is grouped with Sorbitan Olivate under the name Olivem 1000.

Emulsifiers prevent oils and waters from separating.

Studies show Cetearyl alcohol is non-toxic and non-irritating. The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient is usually derived from plant oils such as palm, vegetable, or coconut oils. There is debate on whether this ingredient will cause acne.

Due to the fatty acid base, this ingredient may not be Malassezia folliculitis safe.

Manufacturers sell sorbitan olivate under the name OliveM 1000. OliveM 1000 a multifunctional ingredient. It is self-emulsifying. According to a manufacturer, OliveM 1000 does not disrupt natural skin biome.

Due to its olive oil base, this ingredient may not be fungal-acne safe.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Titanium dioxide provides broad-spectrum protection mostly in the UVB and UVAII range, with some protection in the UVAI range.

While its UVA protection isn’t as strong as zinc oxide’s, the difference is minor.

A common myth is that mineral UV filters reflect UV light. However, modern research shows titanium dioxide absorbs UV radiation like chemical filters (~95% absorption & 5% reflection).

Thanks to its non-irritating nature, titanium dioxide is suitable for sensitive, acne-prone, or redness-prone skin. It is unlikely to cause "eye sting" like other sunscreen ingredients.

A major drawback of this ingredient is its white cast and thick texture. This is why mineral sunscreens often leave a white cast and are less cosmetically elegant than chemical/hybrid sunscreens.

To improve white cast and spreadability, micronized or nano-sized titanium dioxide is often used.

There are ongoing concerns surrounding nano-titanium oxide's impact on marine ecosystems.

There is no conclusive evidence that any form of titanium oxide (or any other sunscreen ingredients) will cause harm to marine ecosystems or coral reefs. The science is still developing but many consumers are keeping a close eye on this issue.

Please note, many destinations have reef-safety sunscreen rules. For instance, the U.S. Virgin Islands advises all visitors to use non-nano mineral sunscreens.

Nano mineral sunscreens once raised safety concerns about absorption into skin.

Extensive research has shown that they do not penetrate healthy or damaged skin; they remain safely on the surface and the top layer of dead skin (stratum corneum).

You'll likely find titanium dioxide bundled with alumina, silica, or dimethicone. These ingredients help make titanium dioxide highly photostable; this prevents it from interacting with other formula components under UV light.

As a polysaccharide, Maltodextrin has moisturizing properties. Polysaccharides are a type of carbohydrate. The top layer of skin uses polysaccharides to retain water, keeping the skin hydrated.

Maltodextrin is water soluble and has a sweet taste.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan?

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Is squalane an oil?

Squalane is often called an oil, but it’s technically not; it’s a hydrocarbon, meaning it’s only made of carbon and hydrogen, unlike true oils which are triglycerides made of fatty acids and glycerol.

The term “oil-free” isn’t regulated, so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

While some people avoid oils thinking they cause breakouts, the right kind of oil (or oil-like ingredient like squalane) can actually help balance and hydrate your skin. It’s worth testing out simple oils or squalane to see what works best for your skin.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Because it’s oil-soluble, THD dives deep into your skin’s fatty layers (think ceramides and cholesterol) to fight off the kind of free radicals that mess with your skin barrier. This makes it a great pair with water-based vitamin C (ascorbic acid) that mainly works on the surface.

Even at just 0.1%, THD is already showing great antioxidant activity. When used up to 2%, it helps keep your skin happy and calm, especially when it’s stressed from pollution or sun.

Want to fade dark spots or tackle hyperpigmentation? You’ll want 5% or more. Pairing it with brightening buddies like niacinamide or licorice root gives even better results. One study even used 30% THD with other brighteners and saw real results on stubborn discoloration, even in melasma-prone skin.

A note on THD: It’s has a slightly silky, oily texture and usually shows up colorless or pale yellow (though the exact shade can vary by supplier).

While you can sneak it into water-based formulas, it really shines when paired with silicones or oils, which help your skin soak it up better.

THD is pretty stable, but it’s still vulnerable to degradation like ascorbic acid. Too much light or heat (above 113°F / 45°C) can break it down over time. Go for dark and opaque packaging that keeps it safe and shady!

Read more about other types of Vitamin C:

Isostearic Acid is created from oleic acid.

This ingredient may not be Malassezia folliculitis, or fungal-acne safe.

As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.

As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.

This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.

Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.

We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.

Some other names for this ingredient include soy lecithin and deoiled soy lecithin.

Polyhydroxystearic Acid may not be fungal acne safe.

Studies show retinal may work at a faster rate than retinol due to its structure.

All retinoids have to be converted into retinoic acid before starting to work. Some retinoids take several steps of conversion before binding. Retinal is only one step away, making it more potent.

Like other retinoids, retinal may be irritating. It is best to ease into using this ingredient frequently.

Using the 'ramp up' method, start by using retinol once a week. This gives your skin time to adjust and decrease irritation. Once you feel ready, you can slowly increase the frequency of retinol use.

Using retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

Carotenoids and Vitamin E help nourish your skin's natural barrier. This barrier protects your skin and is responsible for firm skin.

As an emollient, moringa seed oil helps trap moisture in the skin by creating a film on top. This helps keep your skin hydrated and soft.

Many compounds in moringa seed oil are antioxidant and anti-inflammatory. These compounds include Vitamin E. , catechins, ferulic acid, and more.

Another compound found in Moringa seed oil is oleic acid.

Moringa trees are native to the Himalayan mountains.

This ingredient may not be fungal-acne safe.

This ingredient has skin conditioning, anti-inflammatory, and humectant properties. Humectants help hydrate your skin by drawing moisture from the air. This helps keep your skin moisturized.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.

Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.

Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.

Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.

For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.

After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.

While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.

Read more about other common types of peptides here:

This ingredients tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.

Thus, Matrixyl may help improve the look of wrinkles.

Read more about other common types of peptides here:

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.

The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.

However, it was recently restricted for use in the UK as of April 2024.

Studies find EGF help with:

In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.

According to Dr. Zoe Draelos, growth factors have some drawbacks:

There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.

There is also controversy surrounding EGF. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.

Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.

Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.

Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.

This honeysuckle is native to East Asia and used in traditional Chinese medicine to treat fever and inflammation.

Honeysuckle contains flavonoids and saponins. Both of these components are natural antioxidants that can help soothe the skin.

As most flowers do, honeysuckle has a natural fragrance.