BOH Bio Heal Probioderm 3D Lifting Cream Versus Lepique Glass Skin 14 Days Miracle Retinol Night Cream
This anti-aging moisturizer is formulated around Lactobacillus Ferment Lysate and Adenosine to soften the look of wrinkles.
This anti-aging night moisturizer is formulated around Retinol and Centella Asiatica Extract to soften the look of wrinkles and refine skin texture.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningLactobacillus Ferment Lysate
Skin ConditioningGlycerin
HumectantDipropylene Glycol
HumectantCaprylic/Capric Triglyceride
MaskingCetearyl Alcohol
EmollientLimnanthes Alba Seed Oil
Skin ConditioningGlycereth-26
HumectantVinyldimethicone
Hydrogenated Poly(C6-14 Olefin)
EmollientHydrogenated Polydecene
EmollientPolyglyceryl-3 Methylglucose Distearate
EmulsifyingGlyceryl Stearate
EmollientBetaine
HumectantPolyglycerin-3
Humectant1,2-Hexanediol
Skin ConditioningCetearyl Olivate
Pentylene Glycol
Skin ConditioningPhytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate
Skin ConditioningLactobacillus Ferment
Skin ConditioningFructooligosaccharides
HumectantFructan
Skin ConditioningInulin
Skin ConditioningPanthenol
Skin ConditioningBeta-Glucan
Skin ConditioningAdenosine
Skin ConditioningSaponins
CleansingSoluble Proteoglycan
Skin ConditioningNonapeptide-1
Skin ConditioningAcetyl Tetrapeptide-9
Skin ConditioningAcetyl Tetrapeptide-5
HumectantAcetyl Hexapeptide-1
Skin ConditioningAcetyl Hexapeptide-8
HumectantPalmitoyl Tripeptide-8
Skin ConditioningDipeptide Diaminobutyroyl Benzylamide Diacetate
Skin ConditioningCopper Tripeptide-1
Skin ConditioningTripeptide-1
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningPalmitoyl Tripeptide-1
Skin ConditioningPalmitoyl Tripeptide-5
Skin ConditioningPalmitoyl Pentapeptide-4
Skin ConditioningPalmitoyl Hexapeptide-12
Skin ConditioningPentapeptide-3
Skin ConditioningHexapeptide-9
Skin ConditioningOligopeptide-2
Skin ConditioningMalt Extract
Skin ProtectingDioscorea Japonica Root Extract
Skin ConditioningElaeis Guineensis Oil
EmollientBehenyl Alcohol
EmollientSorbitan Olivate
EmulsifyingButyrospermum Parkii Butter
Skin ConditioningDipentaerythrityl Hexahydroxystearate/Hexastearate/Hexarosinate
Skin ConditioningHydrogenated Rapeseed Oil
EmollientHydroxyacetophenone
AntioxidantSodium Polyacrylate
AbsorbentHydrolyzed Jojoba Esters
Skin ConditioningPEG-100 Stearate
SurfactantEthylhexylglycerin
Skin ConditioningAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingXanthan Gum
EmulsifyingTromethamine
BufferingButylene Glycol
HumectantMaltodextrin
AbsorbentCyanocobalamin
Skin ConditioningCetyl Ethylhexanoate
EmollientPropanediol
SolventCetearyl Glucoside
EmulsifyingAlgin
MaskingSodium Stearoyl Glutamate
CleansingTocopherol
AntioxidantBiosaccharide Gum-4
Skin ConditioningMineral Salts
Skin ConditioningHydrolyzed Corn Starch
HumectantSodium Phosphate
BufferingCaprylyl Glycol
EmollientSucrose
HumectantDextran
Disodium Phosphate
BufferingParfum
MaskingWater, Lactobacillus Ferment Lysate, Glycerin, Dipropylene Glycol, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Limnanthes Alba Seed Oil, Glycereth-26, Vinyldimethicone, Hydrogenated Poly(C6-14 Olefin), Hydrogenated Polydecene, Polyglyceryl-3 Methylglucose Distearate, Glyceryl Stearate, Betaine, Polyglycerin-3, 1,2-Hexanediol, Cetearyl Olivate, Pentylene Glycol, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Lactobacillus Ferment, Fructooligosaccharides, Fructan, Inulin, Panthenol, Beta-Glucan, Adenosine, Saponins, Soluble Proteoglycan, Nonapeptide-1, Acetyl Tetrapeptide-9, Acetyl Tetrapeptide-5, Acetyl Hexapeptide-1, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-8, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Copper Tripeptide-1, Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Pentapeptide-4, Palmitoyl Hexapeptide-12, Pentapeptide-3, Hexapeptide-9, Oligopeptide-2, Malt Extract, Dioscorea Japonica Root Extract, Elaeis Guineensis Oil, Behenyl Alcohol, Sorbitan Olivate, Butyrospermum Parkii Butter, Dipentaerythrityl Hexahydroxystearate/Hexastearate/Hexarosinate, Hydrogenated Rapeseed Oil, Hydroxyacetophenone, Sodium Polyacrylate, Hydrolyzed Jojoba Esters, PEG-100 Stearate, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Xanthan Gum, Tromethamine, Butylene Glycol, Maltodextrin, Cyanocobalamin, Cetyl Ethylhexanoate, Propanediol, Cetearyl Glucoside, Algin, Sodium Stearoyl Glutamate, Tocopherol, Biosaccharide Gum-4, Mineral Salts, Hydrolyzed Corn Starch, Sodium Phosphate, Caprylyl Glycol, Sucrose, Dextran, Disodium Phosphate, Parfum
Water
Skin ConditioningHydrogenated Polydecene
EmollientOctyldodecanol
EmollientGlycerin
HumectantButylene Glycol
HumectantCetearyl Alcohol
EmollientHydrogenated Coconut Oil
Emollient1,2-Hexanediol
Skin ConditioningHydrogenated Vegetable Oil
EmollientGlyceryl Stearate
EmollientHydrolyzed Collagen
EmollientCetearyl Olivate
Simmondsia Chinensis Seed Oil
EmollientSorbitan Olivate
EmulsifyingMethylpropanediol
SolventC14-22 Alcohols
Emulsion StabilisingSodium Hyaluronate
HumectantHydrolyzed Hyaluronic Acid
HumectantHyaluronic Acid
HumectantPentylene Glycol
Skin ConditioningMethyl Glucose Sesquistearate
EmollientCarbomer
Emulsion StabilisingC12-20 Alkyl Glucoside
EmulsifyingRetinol
Skin ConditioningBetaine
HumectantCaprylic/Capric Triglyceride
MaskingTocopherol
AntioxidantPhaseolus Radiatus Seed Extract
Skin ConditioningTromethamine
BufferingPolyglutamic Acid
Skin ConditioningHydrogenated Lecithin
EmulsifyingAdenosine
Skin ConditioningDisodium EDTA
Alteromonas Ferment Extract
Skin ConditioningPhenethyl Alcohol
MaskingCentella Asiatica Extract
CleansingTocopheryl Acetate
AntioxidantMadecassoside
AntioxidantPentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
AntioxidantGlucose
HumectantAsiaticoside
AntioxidantParfum
MaskingLimonene
PerfumingLinalool
PerfumingWater, Hydrogenated Polydecene, Octyldodecanol, Glycerin, Butylene Glycol, Cetearyl Alcohol, Hydrogenated Coconut Oil, 1,2-Hexanediol, Hydrogenated Vegetable Oil, Glyceryl Stearate, Hydrolyzed Collagen, Cetearyl Olivate, Simmondsia Chinensis Seed Oil, Sorbitan Olivate, Methylpropanediol, C14-22 Alcohols, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Pentylene Glycol, Methyl Glucose Sesquistearate, Carbomer, C12-20 Alkyl Glucoside, Retinol, Betaine, Caprylic/Capric Triglyceride, Tocopherol, Phaseolus Radiatus Seed Extract, Tromethamine, Polyglutamic Acid, Hydrogenated Lecithin, Adenosine, Disodium EDTA, Alteromonas Ferment Extract, Phenethyl Alcohol, Centella Asiatica Extract, Tocopheryl Acetate, Madecassoside, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Glucose, Asiaticoside, Parfum, Limonene, Linalool
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineBetaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.
Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.
Some studies suggest betaine may support making skin tone more even.
Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.
Betaine is also known as trimethylglycine.
Learn more about BetaineButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCaprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideCetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Learn more about Cetearyl AlcoholCetearyl Olivate is a plant-derived emulsifier and texture enhancer. It helps keep the oil and water phases from separating so your formulas stay stable.
You'll likely see it combined with Sorbitan Olivate (together sold as the trade name Olivem 1000). This combination generates a liquid crystal structure that closely resemble the lipid organization of the stratum corneum.
These "skin-like" liquid crystals improve skin barrier integrity and promote the delivery of actives into the skin.
This ingredient is well-tolerated and has no significant sensitization data.
Because it is derived from the fatty acids in olive oil, this ingredient may not be fungal acne safe.
Learn more about Cetearyl OlivateGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinGlyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearateHydrogenated Polydecene is a synthetic emollient. It forms a non-occlusive film on the skin's surface to provide a silky feel without being greasy.
In vivo studies in volunteers with atopic and dry skin showed no irritation or intolerance. The volunteers also saw a positive effect in dryness, scaling, and roughness after 28 days of use.
Concentrations up to 100% in guinea pig tests found it to be non-sensitizing and completely safe for use in cosmetics.
Learn more about Hydrogenated PolydeceneParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumPentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolSorbitan Olivate is created from the fatty acids in olive oil and sorbitol.
This ingredient is an oil in water emulsifier. It helps stabilize a product by preventing oils and waters from separating. Sorbitan Olivate also helps hydrate the skin.
This ingredient is also known as part of Olivem 1000, with Cetearyl Olivate being the other part.
According to a manufacturer, this ingredient helps preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria.
Please note, having a healthy microbiome is different from fungal acne; a healthy microbiome includes small amounts of yeast that normally live on your skin without causing problems.
Fungal acne happens when one type of yeast (Malassezia) grows out of control. This is usually because it's feeding on certain oils or fatty acids. Due to the olive oil base, this ingredient may not be fungal acne safe.
Learn more about Sorbitan OlivateTocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolTromethamine (aka THAM) is a synthetic amino acid that shows up in skincare as a helper ingredient.
It functions as a pH adjuster to help neutralize acidic ingredients and set a formula's pH to the right spot.
This matters a lot because a lot of actives (like vitamin C) needs a specific pH to work well and feel comfortable on skin.
Concentration use ranges from 0.1-1.0% depending on the formula.
Learn more about TromethamineWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water