Su:m37 Skin Saver Essential Cleansing Foam

Research indicates that this ingredient posts a low risk of irritation and sensitization.

Since myristic acid is a C14 fatty acid, it falls within the range that Malassezia can metabolize, and therefore not fungal acne safe.

Using high concentrations of Potassium Hydroxide have shown to irritate the skin.

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Lactic acid is one of the more well-studied AHAs in skincare:

Fermentation also adds some bonus phenolic compounds with antioxidant activity.

The only catch with this ingredient is that it is difficult to tell how much lactic acid is in any given product. Ferment filtrates don't come with standardized acid concentration like a 5% lactic acid serum would; this just means the actual exfoliating effect will vary depending on the formula's overall percentage and pH.

Remember that AHAs make your skin more sun-sensitive, so be sure to wear sunscreen.

The fermentation part is interesting:

Research on fermented barley by-products shows that fermentation raises free amino acid, phenolic, and mineral content while breaking down larger molecules. This makes it easier for these compounds to absorb into skin and also gives the filtrate antioxidant potential.

An in vitro study on young barley extract found it boosted fibroblast survival/ migration after UVB exposure and lowered the enzymes that chew through collagen.

Related yeast ferment filtrates point the same direction; rice ferment filtrate increased collagen gene expression and reduced oxidative/inflammatory stress in skin cells.

Brands don't typically publish concentrations for this ingredient but it's used in low levels (commonly under a few percent).

Overall, this is a nice hydrating ingredient that can be added to any routine. Just keep in mind that the direct clinical proof is still thin at this time.

The isoflavones are the workhorses behind the common claims; lab and animal studies show they mop up free radicals, help protect skin cells from UVB damage, and nudge fibroblasts to make more collagen while slowing the enzymes that break collagen down.

One controlled clinical study using an isoflavone cream reported softer wrinkles and better skin texture over time. A topical fermented soy extract also improved hydration and elasticity in an animal aging model.

The big caveat is that most of this evidence comes from soy isoflavones and related fermented soy extracts rather than this exact INCI. Some of the strongest data also comes from oral studies.

So it's best to think of this ingredient as a gentle, antioxidant-leaning conditioning agent rather than a proven wrinkle eraser.

At this time, there's no published concentration levels for this specific ferment but it usually shows up at modest levels in real products (~1% or less).

One last thing for people with soy allergies: it's always worth patch testing this ingredient despite the lowered allergy risk.

You can read about the skin benefits of the individual parts here:
Saccharomyces
Black tea

Citrus Unshiu Peel Extract is unique in that the peel contains very low levels of furanocoumarins and tested products with this ingredient confirmed no detectable furanocoumarins.

The peel is rich in antioxidants and lab studies show it can help brighten skin by inhibiting tyrosinase, the enzyme responsible for melanin production.

One study on the fermented version of this ingredient found it could help reduce UVA-induced collagen breakdown. Though it is worth noting that while results are promising, robust human clinical trials are still needed.

This ingredient naturally contains limonene and other aromatic compounds that make it a perfuming ingredient.

The official COSING database only lists this ingredient as having "Perfuming" properties at this time. The brightening, antioxidant, and skin conditioning benefits that brands market come from the research literature and from how formulators choose to use the ingredient.

Vitamins C and A also provide plenty of skin benefits such as boosting collagen production and helping to reduce the signs of aging.

For those with allergies, Yuzu does contain limonene and linalool. Both these compounds may cause skin sensitivity. If you have concerns, we recommend speaking with a professional.

Early studies suggest it may also help reduce hyperpigmentation by interrupting certain skin processes but more research is needed.

It's pretty compatible with most ingredients, but just sure to space out enzyme products with strong acids/retinoids to avoid over-doing it.

Maximum reported concentration is around 0.1% and most leave-on products use just 0.05%. If you see higher figures like 5-10%, this is usually the pre-diluted material from raw extract suppliers.

This ingredient has an assuring safety record and there's a lack of clinical case reports of dermatitis from using it.

The only caveat is allergy: patch test if you have a papaya or latex-fruit allergy.

Vitamins A and C also have plenty of skin benefits as well.

Lycopene is a potent antioxidant. Besides helping to protect your skin against free-radical molecules, it also helps soothe the skin. Lycopene gives watermelon the distinct red color.

Peach extract is also an abrasive. Abrasives are an agent used to wear away the surface of skin. They are used to help polish or exfoliate skin.

Emerging research shows Peach extract may help protect UV-B induced skin damage. However, further research is needed.

As a humectant, figs are able to draw moisture from the air to your skin. This helps keep your skin hydrated.

Some studies suggest this ingredient may inhibit pigment production in the skin to help even out skin tone.

Polysaccharides help hydrate the top layer of skin due to its ability to mimic natural carbohydrates.

Another study from 2025 found that cabbage leaf extract strong tyrosinase inhibition comparable to vitamin C.

Overall, this is a great supportive ingredient. Be sure to patch test if you have a known allergy to plants in the Brassicaceae family (broccoli, kale, cauliflower).

Beta-carotene is the reason we turn orange if we eat too many carrots.

It should be noted coming into contact with the leaves of wild carrots can cause skin irritation. The sap causes phytophotodermatitis, or sensitivity exposed to sunlight.

This ingredient is created using the edible parts of the carrot.

Besides being rich in antioxidants, red onions also contain sulfur, sugars, Vitamin C, and biotin.

A study from 2018 found onion extract to be just as effective as healing surgical scars as traditional silicone gel.

Another study from 2008 showed using this ingredient helped reduce surgical scar texture, redness, and overall appearance in 60 patients.

According to a manufacturer, this ingredient can help with the following:

Another manufacturer from Spain claims onion extract can inhibit the release of allergy hormones and prostaglandin, or lipids found near tissue damage and infection spots.

This ingredient is water-soluble.

Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.

Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.

Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.

Heart Leaf is rich in flavonoids such as quercetin, apigenin, and more. It also contains polysaccharides, the most common type of carbs in food.

Flavonoids have been shown to be effective antioxidants. They help neutralize free-radical molecules. Free-radical molecules are unstable molecules that may damage our skin cells and DNA. The flavonoids in Heart Leaf also help soothe the skin.

Polysaccharides are naturally found in our skin. They play a role in hydrating and repairing the top layer of skin. The polysaccharides in Heart Leaf help moisturize our skin.

Studies show decanoyl acetaldehyde, a component of Heart Leaf oil, is effective at killing bacteria.

The name 'Fish Mint' comes from the herb's natural fishy smell. Is is native to southeast Asia and used throughout the continent for traditional cooking and medicine.

Antioxidant components in chamomile make it an effective ingredient to help slow the signs of aging. Antioxidants help fight free-radical molecules, or molecules that may damage your skin.

Essential oils from chamomile have been found to improve wound healing due to its antimicrobial properties.

Ancient Greeks and Egyptians used Chamomile to treat skin redness and dryness. Chamomile has also been used to help treat stomach issues.

Another study using a cream with horsetail and soybean extract found 80% of participants showed at least a 26% improvement in forehead wrinkles after 8 weeks.

Animal research has shown topical Equisetum Arvense stimulated skin and tissue growth in mice.

The research so far is encouraging, but still in its early days. But it's a lovely supporting ingredient and can be a welcome addition to any routine.

A few studies show topical products containing safflower extracts might improve elasticity, hydration, and wrinkle appearance. However, replication and formulation-specific details are needed to confirm these effects broadly.

People with Asteraceae allergies (marigold, chamomile) may react to safflower extracts. Be sure to patch test.

The antioxidant properties help protect your body from free-radicals. Free-radicals are molecules that may damage your skin cells. As a result, ginger may help slow down signs of aging such as hyperpigmentation and wrinkles.

Studies show ginger inhibits the enzyme that breaks down collagen. It also helps with:

This ingredient has no negative side-effects and is safe to use unless one has a specific allergy to it.

Ginger originates from Southeast Asia but has spread throughout the world. It is now a common spice used in many cultures.

Beet root has many benefits when eaten. More research is needed on applying beetroot in skincare.

Beet Root is used to add pink/red color.

Curcumin also has anti-inflammatory properties and can help soothe skin and reduce irritation. On top of that, curcumin has been shown to help prevent hyperpigmentation from sun damage.

The anti-microbial property of turmeric can make it effective in treating acne. This property has also been shown to help regulate the production of sebum.

The fatty acids found in sunflower seeds include (from highest amount to least): linoleic acid, myristic acid, palmitic acid, stearic acid, arachidic acid, oleic acid, and linolenic acid.

These fatty acids hydrate your skin. Emollients create a film on the skin to prevent moisture from escaping.

These compounds protect your skin two ways:

1) They fight off free radicals, or the unstable molecules from things like sun and pollution that age and damage skin.
2) They help calm inflammation by switching off the chemical signals that tell skin to get red and irritated.

Lab studies also suggest that rosmarinic acid may help protect collagen and slow sugar-related damage to it.

The Cosmetic Ingredient Review has concluded rosemary-derived ingredients to be safe when formulated to be non-sensitizing.

Rosemary can occasionally cause allergic contact dermatitis (due to carnosol), so be sure to patch test if you have reactive or fragrance-sensitive skin.

This honeysuckle is native to East Asia and used in traditional Chinese medicine to treat fever and inflammation.

Fun fact: Purslane is a succulent with an extensive habitat. It is used in traditional Korean medicine to treat irritated skin.

Nowadays, purslane is becoming a superfood due to its highly nutritious content.

Zhi Mu root is rich in sarsasapogenin. This compound has anti-inflammatory and soothing properties.

It is commonly used in East Asian medicine.

These compounds allow centella to dial back inflammation, encourage the skin to build and hold onto collagen, support the barrier and hydration, and bring solid antioxidant activity to protect against signs of aging.

Centella also carries a nice supporting cast of Vitamin A, vitamin C, several B vitamins, and amino acids. Put it all together and you get an ingredient that soothes, hydrates, and protects, all at once.

Most of centella's magic comes from the four big compounds (Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid). These are the actives doing the heavy lifting in almost every centella study.

Here is the short version of what they do in the skin:

So it is not just soothing for the sake of soothing. Centella calms the skin AND helps it rebuild.

Just FYI, not all centella on an ingredient list is the same. What you are getting actually depends on the extract:

Fun fact on the ratios: the leaves tend to be richest in Madecassoside and Asiaticoside, and lower in the two acids. The exact amounts shift with where the plant is grown and how it is processed. This means purity really does vary brand to brand.

Centella is one of the most easygoing actives out there.

It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs nicely with stronger actives like retinoids and exfoliating acids where it can help take the edge off irritation.

On the safety side, centella and its triterpenes are classified as weak sensitizers, meaning allergic reactions are possible but uncommon.

Patch tests at 1% and 5% came back negative in test panels, and creams at typical use levels did not cause allergic reactions across large groups of people.

But as with any new active, a patch test is still a smart move for very reactive skin.

Centella is widely used because it is effective at low percentages. For context, human safety testing found no meaningful irritation from creams containing centella extract at everyday use levels (the tested amounts were well under 1%).

The irritancy threshold in animal testing was also above 30% (so real-world formulas sit far below anything concerning).

In collagen lab studies, higher concentrations drove more collagen synthesis, so serums built around centella tend to feature it more prominently.

Bottom line: you will find centella working nicely anywhere from a fraction of a percent up to hero-ingredient levels depending on whether it is a supporting soother or the main event.

Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

This extract is created by using 50% 1,3-Butylene glycol.

Traditional Iranian folk medicine uses Lavender extract to help treat inflammation.

Lavender extract may have a scent.

It contains linalool, a known allergen. However, lavender extract contains less linalool than lavender essential oil.

Vitamins C and E are potent antioxidants and may help with anti-aging. The fatty acids are emollients that help soften and hydrate your skin.

Another potent vitamin found in rosehip is Vitamin A, or retinol. Retinol encourages collagen production in the skin.

Rosehip extract may help with brightening the skin. Several components, such as beta-carotene, are able to reduce pigmentation caused by sun damage.

Fun fact: Polyglutamic Acid is found in the Japanese food, natto. It is also being used in cancer treatment studies.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Methylpropanediol is able to add a bit of moisture to the skin. It also helps other ingredients be better absorbed into the skin, such as salicylic acid.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Lab studies credit this oil with antioxidant, anti-inflammatory, and antimicrobial activity. Some research even show rosemary compounds calming acne-related inflammation.

The Cosmetic Ingredient Review (CIR) has concluded rosemary-derived ingredients to be safe when formulated to be nonsensitizing.

Since this is a fragrant essential oil, the main concern is for fragrance-sensitive folks.

The scent of Rose Geranium closely resembles traditional roses.

Terpinen-4-ol is responsible for tea tree oil's broad-spectrum antimicrobial activity and makes it a well-researched option for acne.

Clinical studies support 5% tea tree oil as an effective topical treatment for mild to moderate acne. A study with 124 patients compared 5% tea tree oil gel to 5% benzoyl peroxide and both reduced acne (though tea tree oil worked more slowly).

Besides acne, it is also seen in anti-dandruff shampoos and scalp treatments for it's antimicrobial and anti-seborrheic properties.

Safety-wise, the allergic potential of low concentrations on healthy skin is considered low. However, oxidized (old or improperly stored) tea tree oil is a stronger sensitizer.

Irritation can also occur if using the undiluted oil on skin; it's best to use this ingredient as part of a carefully crafted cosmetic formula. This is because regulations require tea tree oil in cosmetics to be stabilized to prevent degradation.

This ingredient has been deemed safe up to 2% in shampoo, 1% in cleansers, and 0.1% in face cream by the EU's Scientific Committee on Consumer Safety (SCCS).

There is some lab evidence that tea tree oil is antifungal against Malassezia, but it is a supportive option at best and not a replacement for proven antifungal treatments.

The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.

When used topically, Citrus Aurantium Bergamia Fruit Oil is a photosensitizer due to the furanocoumarin content. Furanocoumarins absorb UV-A and cause phytophotodermatitis; this can look like redness, blistering, and lasting brown pigmentation on sun-exposed skin.

Due to this, this ingredient is capped at 0.4% in leave-on products applied to sun exposed skin.

Many modern formulas used a "furanocoumarin-free" version that sidesteps the phototoxicity issue, but still contains the fragrance allergens.

Limonene acts as an antioxidant, meaning it helps neutralize free radicals.

When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.

The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.