Versus

Neogen Surmedic Super Glutathione 100 Bright Tone Up Cream Versus APLB Glutathione Niacinamide Ampoule Serum

Facial Treatment
Serum
Korean Brand South Korea
Korean Brand South Korea

Updated on January 15, 2025

Overview

Cool Features

They both contain hyaluronic acid and niacinamide

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, parabens or sulfates

What's Inside

They both contain fragrances

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Ingredients Side-by-side

found in both products
Surmedic Super Glutathione 100 Bright Tone Up Cream

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Triethylhexanoin

Masking

Hydrogenated Poly(C6-14 Olefin)

Emollient

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Titanium Dioxide

Cosmetic Colorant
0 / 0 Mineral UV Filter IconNon-Reef-Safe Icon

Caprylic/Capric Triglyceride

Masking

1,2-Hexanediol

Skin Conditioning

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Propanediol

Solvent

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Cyclopentasiloxane

Emollient
Silicon Icon

Phenyl Trimethicone

Skin Conditioning
Silicon Icon

C12-15 Alkyl Benzoate

Antimicrobial

Cyclohexasiloxane

Emollient
Silicon Icon

Cetyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Stearyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Silica

Abrasive
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon

Tromethamine

Buffering

Carbomer

Emulsion Stabilising
1 / 0

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Alumina

Abrasive
Exfoliant Icon

Aluminum Stearate

Cosmetic Colorant

Ethylhexylglycerin

Skin Conditioning

Polyhydroxystearic Acid

Emulsifying
Not safe for Fungal Acne Icon

Aluminum Hydroxide

Emollient

Triethoxycaprylylsilane

Adenosine

Skin Conditioning
Good for Minimizing Pores IconGood for Scar Healing Icon

Xanthan Gum

Emulsifying

Glutathione

Good for Dark Spots Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Camellia Japonica Seed Oil

Emollient
Oil IconNot safe for Fungal Acne Icon

Magnesium Ascorbyl Phosphate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Hippophae Rhamnoides Oil

Emollient
Oil IconNot safe for Fungal Acne Icon

Ascorbic Acid

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Pearl Powder

Trehalose

Humectant

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Boron Nitride

Absorbent

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Xylitylglucoside

Humectant

Anhydroxylitol

Humectant

Opuntia Coccinellifera Fruit Extract

Skin Conditioning

Leontopodium Alpinum Callus Culture Extract

Antioxidant
Antioxidant Icon

Xylitol

Humectant

Phaseolus Radiatus Seed Extract

Skin Conditioning

Centella Asiatica Extract

Cleansing
Helps reduce Skin Redness IconHelps reduce irritation Icon

Bifida Ferment Lysate

Skin Conditioning
Helps hydrate Dry Skin Icon

Brassica Campestris Seed Oil

Skin Conditioning
Oil IconNot safe for Fungal Acne Icon

Hydrolyzed Collagen

Emollient
Helps hydrate Dry Skin IconHelps with Anti-Aging Icon

Olea Europaea Fruit Oil

Masking
0-2 / 0 Fragrance IconOil IconNot safe for Fungal Acne Icon

Adansonia Digitata Seed Oil

Emollient
Oil IconNot safe for Fungal Acne Icon

Glucose

Humectant

Hydrogenated Lecithin

Emulsifying

Ceramide 3

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Citrus Limon Fruit Extract

Masking
May cause irritation Icon

Portulaca Oleracea Extract

Skin Conditioning

Citrus Nobilis Fruit Extract

Masking

Malpighia Glabra Fruit Extract

Skin Conditioning

Rumex Crispus Root Extract

Skin Conditioning

Pearl Extract

Antioxidant
Antioxidant Icon

Betula Platyphylla Japonica Bark Extract

Skin Conditioning

Ceramide 2

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide 4

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Ceramide 1

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide AP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Melaleuca Alternifolia Leaf Extract

Perfuming
Fragrance IconGood for Oily Skin Icon

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Parfum

Masking
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Alpha-Isomethyl Ionone

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Citronellol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Linalool

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Limonene

Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Hexyl Cinnamal

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Water, Glycerin, Triethylhexanoin, Hydrogenated Poly(C6-14 Olefin), Butylene Glycol, Titanium Dioxide, Caprylic/Capric Triglyceride, 1,2-Hexanediol, Niacinamide, Propanediol, Polysorbate 20, Cyclopentasiloxane, Phenyl Trimethicone, C12-15 Alkyl Benzoate, Cyclohexasiloxane, Cetyl Alcohol, Stearyl Alcohol, Silica, Tromethamine, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Alumina, Aluminum Stearate, Ethylhexylglycerin, Polyhydroxystearic Acid, Aluminum Hydroxide, Triethoxycaprylylsilane, Adenosine, Xanthan Gum, Glutathione, Tocopheryl Acetate, Camellia Japonica Seed Oil, Magnesium Ascorbyl Phosphate, Hippophae Rhamnoides Oil, Ascorbic Acid, Allantoin, Pearl Powder, Trehalose, Panthenol, Boron Nitride, Helianthus Annuus Seed Oil, Squalane, Xylitylglucoside, Anhydroxylitol, Opuntia Coccinellifera Fruit Extract, Leontopodium Alpinum Callus Culture Extract, Xylitol, Phaseolus Radiatus Seed Extract, Centella Asiatica Extract, Bifida Ferment Lysate, Brassica Campestris Seed Oil, Hydrolyzed Collagen, Olea Europaea Fruit Oil, Adansonia Digitata Seed Oil, Glucose, Hydrogenated Lecithin, Ceramide 3, Citrus Limon Fruit Extract, Portulaca Oleracea Extract, Citrus Nobilis Fruit Extract, Malpighia Glabra Fruit Extract, Rumex Crispus Root Extract, Pearl Extract, Betula Platyphylla Japonica Bark Extract, Ceramide 2, Ceramide 4, Hyaluronic Acid, Tocopherol, Ceramide 1, Ceramide AP, Melaleuca Alternifolia Leaf Extract, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Parfum, Alpha-Isomethyl Ionone, Citronellol, Linalool, Limonene, Hexyl Cinnamal

Glutathione Niacinamide Ampoule Serum

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.
  • It has mild preservative properties.

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Smoothing

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum

Glutathione is an antioxidant naturally found in our bodies. It is made up of three amino acids: glycine, cysteine, and glutamic acid.

As an antioxidant, it prevents oxidative damage to parts of our cell.

While glutathione is said to help with fading dark spots, the results from research are inconclusive. Further studies are needed. With that said, gluthatione has been shown to protect our skin from UV-B induced damage.

This ingredient is naturally occurring in plants, animals, fungi, and some bacteria.

Learn more about Glutathione
Skin Conditioning, Skin Protecting, Soothing

Allantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.

Some studies have shown this ingredient can promote wound healing with higher concentrations.

Allantoin is derived from the comfrey plant but produced synthetically for cosmetic products to ensure purity.

Learn more about Allantoin
Skin Conditioning

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Learn more about Panthenol
Emollient, Skin Conditioning

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan?

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Learn more about Squalane
Cleansing, Skin Conditioning, Smoothing

Centella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.

Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.

Studies show the compounds in centella help with:

The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.

Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.

Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Learn more about Centella Asiatica Extract
Emollient, Humectant, Skin Conditioning

Hydrolyzed collagen has a misleading name because it is actually a mixture of various proteins/peptides. This ingredient has skin hydrating properties.

Collagen is the most abundant type of structural protein found in your body. In your skin, it is responsible for keeping it firm and youthful.

Hydrolyzed Collagen is created by breaking up proteins into smaller peptide bonds. These peptides act as humectants and emollients.

Humectants are great at holding onto water, keeping skin hydrated. Emollients create a thin barrier on the skin to prevent moisture from escaping.

There is ongoing debate about whether hydrolyzed collagen works because it increases skin hydration. Skin hydration is also linked to elasticity and the appearance of wrinkles.

Collagen or peptide ingredients can be used in the morning or night. They will not increase sun sensitivity, but you should always wear sunscreen during the day.

According to a manufacturer, this ingredient is a great hair conditioner as well.

This ingredient can be extracted from different sources, including:

Vegan collagen is derived from yeast, bacteria, or plant sources. Vegan collagen would go by a different INCI name, such as hydrolyzed soy protein.

The results are varied.

A study from 2021 found hydrolyzed collagen increased elasticity and improved wrinkles in 1,125 participants between age 20 and 70. Another study found increased skin thickness in participants between the ages of 45 to 59.

However, It is difficult to prove that oral collagen will end up working on your skin. Many of the studies using hydrolyzed collagen also add several vitamins and nutrients into the test mixture as well.

Further studies are needed at this time.

Learn more about Hydrolyzed Collagen
Humectant

Glucose is a simple sugar and is the most important source of energy in all organisms.

In skincare, glucose is used to hydrate the skin. It also acts as a prebiotic for our natural biome.

Glucose is hydrating due to its humectant property. As a humectant, glucose draws moisture from the air and from deeper levels in the skin.

Our skin contains many sugars that act as prebiotics and help strengthen our natural microbiome. Having a healthy microbiome helps protect our skin from harmful bacteria and other contaminants.

Studies show glucose may help with fading discoloration and pigmentation. This is because our skin metabolizes glucose into lactic acid. Lactic acid is an AHA that helps exfoliate the top layer of skin.

Learn more about Glucose
Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.

This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Perfuming, Skin Conditioning

Melaleuca Alternifolia Leaf Extract comes from the Tea Tree, Melaleuca alternifolia, Myrtaceae. This tea tree is native to Australia.

Tea Leaf extract contains antimicrobial and anti-acne properties.

Tea tree extract is fragrant and contains volatiles such as linalool and limonene. These fragrance and terpinen components can cause skin sensitivity.

Learn more about the benefits of Tea Tree Oil here.

Learn more about Melaleuca Alternifolia Leaf Extract
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate

When to use

103 Routines
50% use in am
51% use in pm
91% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Neogen Surmedic Super Glutathione 100 Bright Tone Up Cream 79 ingredients

Surmedic Super Glutathione 100 Bright Tone Up Cream hasn't been rated yet.
Rate it now

APLB Glutathione Niacinamide Ampoule Serum 45 ingredients

4.5 /5
from 4 ratings
Great Value (3) Works Well (3) Absorbs Well (2)
Lapaki's avatar

Lapaki

8 months ago
Review

I've been using APLB's Glutathione Niacinamide serum twice a day for several months, targeting dark spots and hyperpigmentation, and I don’t regret buying it.

Assessing the impact of a specific product or ingredient can be challenging, given that my routine includes several brightening products. The results are likely a cumulative effect. However, since this serum is one of my newest additions, Show more

#great value
#hydrating
#light
#absorbs well
RemiShen's avatar

Remi Shen

3 months ago
Review

I like the texture of this product and how it feels on the skin. It didn't really do much for my skin and I didn't notice any differences.