Versus

MEDI-PEEL Bio-Intense Glutathione Cream Versus Neogen Surmedic Super Glutathione 100 Bright Tone Up Cream

General Moisturizer
Facial Treatment
Korean Brand
Korean Brand

Updated on January 29, 2025

Overview

Cool Features

They both contain ceramides, hyaluronic acid, niacinamide and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, parabens or sulfates

What's Inside

They both contain silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Surmedic Super Glutathione 100 Bright Tone Up Cream

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Triethylhexanoin

Masking

Hydrogenated Poly(C6-14 Olefin)

Emollient

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Titanium Dioxide

Cosmetic Colorant
0 / 0 Mineral UV Filter IconNon-Reef-Safe Icon

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Propanediol

Solvent
Helps hydrate Dry Skin Icon

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Cyclopentasiloxane

Emollient
Silicon Icon

Phenyl Trimethicone

Skin Conditioning
Silicon Icon

C12-15 Alkyl Benzoate

Antimicrobial

Cyclohexasiloxane

Emollient
Silicon Icon

Cetyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Stearyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Silica

Abrasive
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon

Tromethamine

Buffering

Carbomer

Emulsion Stabilising
1 / 0

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Alumina

Abrasive
Exfoliant Icon

Aluminum Stearate

Cosmetic Colorant

Ethylhexylglycerin

Skin Conditioning

Polyhydroxystearic Acid

Emulsifying
Not safe for Fungal Acne Icon

Aluminum Hydroxide

Emollient

Triethoxycaprylylsilane

Silicon Icon

Adenosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing Icon

Xanthan Gum

Emulsifying

Glutathione

Good for Dark Spots Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Camellia Japonica Seed Oil

Emollient
Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Magnesium Ascorbyl Phosphate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Hippophae Rhamnoides Oil

Emollient
Oil IconNot safe for Fungal Acne Icon

Ascorbic Acid

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Pearl Powder

Trehalose

Humectant
Helps hydrate Dry Skin Icon

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Boron Nitride

Absorbent

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Xylitylglucoside

Humectant
Helps hydrate Dry Skin Icon

Anhydroxylitol

Humectant
Helps hydrate Dry Skin Icon

Opuntia Coccinellifera Fruit Extract

Skin Conditioning

Leontopodium Alpinum Callus Culture Extract

Antioxidant
Antioxidant Icon

Xylitol

Humectant
Helps hydrate Dry Skin Icon

Phaseolus Radiatus Seed Extract

Skin Conditioning

Centella Asiatica Extract

Cleansing
Helps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

Bifida Ferment Lysate

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Brassica Campestris Seed Oil

Skin Conditioning
Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Hydrolyzed Collagen

Emollient
Helps hydrate Dry Skin IconHelps with Anti-Aging Icon

Olea Europaea Fruit Oil

Masking
0-2 / 0 Fragrance IconOil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Adansonia Digitata Seed Oil

Emollient
Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Glucose

Humectant
Helps hydrate Dry Skin Icon

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin Icon

Ceramide 3

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

Citrus Limon Fruit Extract

Masking
May cause irritation Icon

Portulaca Oleracea Extract

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Citrus Nobilis Fruit Extract

Masking

Malpighia Glabra Fruit Extract

Skin Conditioning

Rumex Crispus Root Extract

Skin Conditioning

Pearl Extract

Antioxidant
Antioxidant Icon

Betula Platyphylla Japonica Bark Extract

Skin Conditioning

Ceramide 2

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide 4

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Ceramide 1

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide AP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Melaleuca Alternifolia Leaf Extract

Perfuming
Fragrance Icon

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Parfum

Masking
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Alpha-Isomethyl Ionone

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Citronellol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Linalool

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Limonene

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Hexyl Cinnamal

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Water, Glycerin, Triethylhexanoin, Hydrogenated Poly(C6-14 Olefin), Butylene Glycol, Titanium Dioxide, Caprylic/Capric Triglyceride, 1,2-Hexanediol, Niacinamide, Propanediol, Polysorbate 20, Cyclopentasiloxane, Phenyl Trimethicone, C12-15 Alkyl Benzoate, Cyclohexasiloxane, Cetyl Alcohol, Stearyl Alcohol, Silica, Tromethamine, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Alumina, Aluminum Stearate, Ethylhexylglycerin, Polyhydroxystearic Acid, Aluminum Hydroxide, Triethoxycaprylylsilane, Adenosine, Xanthan Gum, Glutathione, Tocopheryl Acetate, Camellia Japonica Seed Oil, Magnesium Ascorbyl Phosphate, Hippophae Rhamnoides Oil, Ascorbic Acid, Allantoin, Pearl Powder, Trehalose, Panthenol, Boron Nitride, Helianthus Annuus Seed Oil, Squalane, Xylitylglucoside, Anhydroxylitol, Opuntia Coccinellifera Fruit Extract, Leontopodium Alpinum Callus Culture Extract, Xylitol, Phaseolus Radiatus Seed Extract, Centella Asiatica Extract, Bifida Ferment Lysate, Brassica Campestris Seed Oil, Hydrolyzed Collagen, Olea Europaea Fruit Oil, Adansonia Digitata Seed Oil, Glucose, Hydrogenated Lecithin, Ceramide 3, Citrus Limon Fruit Extract, Portulaca Oleracea Extract, Citrus Nobilis Fruit Extract, Malpighia Glabra Fruit Extract, Rumex Crispus Root Extract, Pearl Extract, Betula Platyphylla Japonica Bark Extract, Ceramide 2, Ceramide 4, Hyaluronic Acid, Tocopherol, Ceramide 1, Ceramide AP, Melaleuca Alternifolia Leaf Extract, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Parfum, Alpha-Isomethyl Ionone, Citronellol, Linalool, Limonene, Hexyl Cinnamal

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine
Skin Conditioning, Skin Protecting, Soothing

Allantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.

Some studies have shown this ingredient can promote wound healing with higher concentrations.

Allantoin is derived from the comfrey plant but produced synthetically for cosmetic products to ensure purity.

Learn more about Allantoin
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride
Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Cleansing, Skin Conditioning, Smoothing

Centella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.

Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.

Studies show the compounds in centella help with:

The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.

Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.

Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Learn more about Centella Asiatica Extract
Emollient, Skin Conditioning, Solvent

Cyclopentasiloxane, or D5, is a silicone used to improve texture of products and trap moisture.

D5 is considered lightweight and volatile. Volatile means it evaporates quickly after application. Once evaporated, D5 leaves a thin barrier that helps keep skin hydrated.

It is also an emollient. Emollients help soften the skin and prevent water loss. Silicones create a silky texture in products. D5 helps other ingredients become more spreadable.

Studies show D5 is safe to use in skincare products. We recommend speaking with a skincare professional if you have concerns.

Learn more about Cyclopentasiloxane
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Glutathione is an antioxidant naturally found in our bodies. It is made up of three amino acids: glycine, cysteine, and glutamic acid.

As an antioxidant, it prevents oxidative damage to parts of our cell.

While glutathione is said to help with fading dark spots, the results from research are inconclusive. Further studies are needed. With that said, gluthatione has been shown to protect our skin from UV-B induced damage.

This ingredient is naturally occurring in plants, animals, fungi, and some bacteria.

Learn more about Glutathione
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Moisturising, Skin Conditioning

Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.

This ingredient helps hydrate, soothe, and protect the skin.

What makes hyaluronic acid so hydrating? It has the capacity to bind or hold large amounts of water.

Fun fact: It is already naturally found in our bodies, such as the fluids of our eyes and our joints.

Studies find this ingredient to have anti-inflammatory and anti-microbial properties. This can help speed up wound-healing.

Hyaluronic acid can be irritating if the molecule has a low-molecular weight, or if the molecules are small.

One study found low-molecular weight hyaluronic acid to be pro-inflammatory, meaning some people may experience irritation. This is because our bodies use hyaluronic acid in the wound-healing process to signal to our bodies, via irritation, that something needs healing.

The same study found high-molecular weight hyaluronic acid to be anti-inflammatory.

These are some other common types of Hyaluronic Acid:

Learn more about Hyaluronic Acid
Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide
Skin Conditioning

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Learn more about Panthenol
Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Antioxidant, Masking, Skin Conditioning

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water