Versus

La Mer The Regenerating Serum Versus Musely The Aging Repair Cream

Serum
Prescription
American Brand United States
American Brand United States

Updated on September 18, 2025

Overview

Cool Features

They both contain exfoliants

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any parabens

What's Inside

They both contain oils and silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside

What's inside

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
The Regenerating Serum

Water

Skin Conditioning

Algae Extract

Emollient
May worsen Oily Skin Icon

Dimethicone

Emollient
1 / 0 Silicon Icon

Hdi/Trimethylol Hexyllactone Crosspolymer

Hydrogenated Polyisobutene

Emollient
1 / 2

Caprylic/Capric/Myristic/Stearic Triglyceride

Emollient

Dimethicone/Vinyl Dimethicone Crosspolymer

Skin Conditioning
Silicon Icon

PEG-8 Dimethicone

Emulsifying
Silicon Icon

Triethylhexanoin

Masking

PEG-10 Dimethicone

Skin Conditioning
Silicon Icon

Polysilicone-11

Silicon Icon

Macadamia Integrifolia Seed Oil

Skin Conditioning
Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Decyl Glucoside

Cleansing

Glyceryl Triacetyl Ricinoleate

Emollient
Not safe for Fungal Acne Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Sesamum Indicum Seed Oil

Emollient
1-3 / 0 Oil IconNot safe for Fungal Acne Icon

Medicago Sativa Seed Powder

Skin Conditioning

Helianthus Annuus Seedcake

Abrasive
Exfoliant IconNot safe for Fungal Acne Icon

Prunus Amygdalus Dulcis Seed Meal

Abrasive
Exfoliant Icon

Eucalyptus Globulus Leaf Oil

Perfuming
Fragrance IconOil IconMay cause irritation IconEU Allergen Icon

Sodium Gluconate

Skin Conditioning

Copper Gluconate

Skin Conditioning
Good for Scar Healing Icon

Calcium Gluconate

Humectant

Magnesium Gluconate

Skin Conditioning

Zinc Gluconate

Skin Conditioning
Helps fight Acne Icon

Tocopheryl Succinate

Antioxidant
Antioxidant Icon

Niacin

Smoothing
Helps hydrate Dry Skin IconGood for Dark Spots Icon

Sesamum Indicum Seed Powder

Skin Conditioning

Citrus Aurantifolia Peel Extract

Cleansing
Fragrance Icon

Narcissus Tazetta Bulb Extract

Astringent
May cause irritation IconEU Allergen Icon

Citrus Reticulata Peel Extract

Skin Conditioning

Humulus Lupulus Extract

Antimicrobial

Mimosa Tenuiflora Bark Extract

Skin Protecting

Rosmarinus Officinalis Leaf Extract

Antimicrobial

Melilotus Officinalis Extract

Astringent

Hydrolyzed Wheat Protein

Skin Conditioning

Hydrolyzed Yeast Protein

Skin Conditioning

Marrubium Vulgare Extract

Skin Conditioning

Eryngium Maritimum Extract

Tonic

Bifida Ferment Lysate

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Polygonum Cuspidatum Root Extract

Antioxidant
Antioxidant Icon

Adenosine Phosphate

Skin Conditioning

Acetyl Carnitine Hcl

Skin Conditioning

Creatine

Skin Conditioning

Cladosiphon Okamuranus Extract

Skin Conditioning

Punica Granatum Fruit Juice

Masking

Nordihydroguaiaretic Acid

Antioxidant
Antioxidant Icon

Lactis Proteinum

Skin Conditioning

Ethylbisiminomethylguaiacol Manganese Chloride

Antioxidant
Antioxidant IconHelps reduce Skin Redness IconHelps with Anti-Aging IconGood for Dark Spots Icon

Linolenic Acid

Cleansing
Fragrance IconHelps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconNot safe for Fungal Acne Icon

Caffeine

Skin Conditioning
Helps reduce irritation IconHelps with Anti-Aging Icon

Alcaligenes Polysaccharides

Emollient

Gelidiella Acerosa Extract

Skin Protecting

Dipotassium Glycyrrhizate

Humectant
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Vitis Vinifera Seed Extract

Antimicrobial
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging Icon

Glycine Soja Seed Extract

Skin Conditioning
Helps reduce irritation IconGood for Dark Spots Icon

Gold

Cosmetic Colorant

Hydrolyzed Soy Protein

Humectant
Helps hydrate Dry Skin Icon

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin Icon

Phenyl Trimethicone

Skin Conditioning
Silicon Icon

Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer

Emulsion Stabilising

Isododecane

Emollient

Hypnea Musciformis Extract

Skin Protecting

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Sigesbeckia Orientalis Extract

Skin Conditioning

Dipalmitoyl Hydroxyproline

Skin Conditioning
Not safe for Fungal Acne Icon

Acetyl Glucosamine

Skin Conditioning

Linoleic Acid

Cleansing
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Micrococcus Lysate

Skin Conditioning

Tourmaline

Glycosaminoglycans

Emollient

Soy Amino Acids

Skin Conditioning

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Laminaria Digitata Extract

Skin Protecting
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Yeast Extract

Skin Conditioning
Not safe for Fungal Acne Icon

Trisiloxane

Skin Conditioning
Silicon Icon

Tartaric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Tetraacetylphytosphingosine

Skin Conditioning

Dextrin

Absorbent

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Pentylene Glycol

Skin Conditioning

Bis-Stearyl Dimethicone

Emollient
Silicon Icon

Laureth-12

Emulsifying

Potassium Sorbate

Preservative
Preservative Icon

Parfum

Masking
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Caprylyl Glycol

Emollient
Fatty Alcohol Icon

Lecithin

Emollient
Helps hydrate Dry Skin Icon

Hydroxypropyl Cyclodextrin

Masking

Maltodextrin

Absorbent
Helps hydrate Dry Skin Icon

Cyclodextrin

Absorbent

Alcohol Denat.

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon

Sodium Hydroxide

Buffering

Xanthan Gum

Emulsifying

Silica

Abrasive
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Glutathione

Good for Dark Spots Icon

Polymethylsilsesquioxane

Silicon Icon

Disodium EDTA

BHT

Antioxidant
Antioxidant Icon

Phenoxyethanol

Preservative
Preservative Icon

Limonene

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Linalool

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Hydroxycitronellal

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Citronellol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Geraniol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

CI 61570

Cosmetic Colorant

Water, Algae Extract, Dimethicone, Hdi/Trimethylol Hexyllactone Crosspolymer, Hydrogenated Polyisobutene, Caprylic/Capric/Myristic/Stearic Triglyceride, Dimethicone/Vinyl Dimethicone Crosspolymer, PEG-8 Dimethicone, Triethylhexanoin, PEG-10 Dimethicone, Polysilicone-11, Macadamia Integrifolia Seed Oil, Decyl Glucoside, Glyceryl Triacetyl Ricinoleate, Glycerin, Niacinamide, Sesamum Indicum Seed Oil, Medicago Sativa Seed Powder, Helianthus Annuus Seedcake, Prunus Amygdalus Dulcis Seed Meal, Eucalyptus Globulus Leaf Oil, Sodium Gluconate, Copper Gluconate, Calcium Gluconate, Magnesium Gluconate, Zinc Gluconate, Tocopheryl Succinate, Niacin, Sesamum Indicum Seed Powder, Citrus Aurantifolia Peel Extract, Narcissus Tazetta Bulb Extract, Citrus Reticulata Peel Extract, Humulus Lupulus Extract, Mimosa Tenuiflora Bark Extract, Rosmarinus Officinalis Leaf Extract, Melilotus Officinalis Extract, Hydrolyzed Wheat Protein, Hydrolyzed Yeast Protein, Marrubium Vulgare Extract, Eryngium Maritimum Extract, Bifida Ferment Lysate, Polygonum Cuspidatum Root Extract, Adenosine Phosphate, Acetyl Carnitine Hcl, Creatine, Cladosiphon Okamuranus Extract, Punica Granatum Fruit Juice, Nordihydroguaiaretic Acid, Lactis Proteinum, Ethylbisiminomethylguaiacol Manganese Chloride, Linolenic Acid, Caffeine, Alcaligenes Polysaccharides, Gelidiella Acerosa Extract, Dipotassium Glycyrrhizate, Vitis Vinifera Seed Extract, Acetyl Hexapeptide-8, Glycine Soja Seed Extract, Gold, Hydrolyzed Soy Protein, Hydrogenated Lecithin, Phenyl Trimethicone, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Isododecane, Hypnea Musciformis Extract, Tocopheryl Acetate, Sigesbeckia Orientalis Extract, Dipalmitoyl Hydroxyproline, Acetyl Glucosamine, Linoleic Acid, Micrococcus Lysate, Tourmaline, Glycosaminoglycans, Soy Amino Acids, Butylene Glycol, Laminaria Digitata Extract, Yeast Extract, Trisiloxane, Tartaric Acid, Tetraacetylphytosphingosine, Dextrin, Tocopherol, Pentylene Glycol, Bis-Stearyl Dimethicone, Laureth-12, Potassium Sorbate, Parfum, Caprylyl Glycol, Lecithin, Hydroxypropyl Cyclodextrin, Maltodextrin, Cyclodextrin, Alcohol Denat., Sodium Hydroxide, Xanthan Gum, Silica, Citric Acid, Glutathione, Polymethylsilsesquioxane, Disodium EDTA, BHT, Phenoxyethanol, Limonene, Linalool, Hydroxycitronellal, Citronellol, Geraniol, CI 61570

The Aging Repair Cream

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

BHT
Antioxidant, Masking

BHT is a synthetic antioxidant and preservative.

As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.

As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.

The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.

However, it was recently restricted for use in the UK as of April 2024.

Learn more about BHT
Emollient, Skin Conditioning, Skin Protecting

Dimethicone is a type of synthetic silicone created from natural materials such as quartz.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Learn more about Dimethicone
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Solvent

Isododecane is a fragrance, emollient, and solvent.

As an emollient, it helps your skin stay soft and hydrated. Emollients help trap moisture into your skin.

Isododecane's role as a solvent makes it a great texture enhancer. It spreads smoothly on skin and does not leave a sticky feeling behind. Isododecane also helps prevent color transfer in makeup products.

Isododecane is not absorbed into skin.

Learn more about Isododecane
Emulsifying

We don't have a description for Laureth-12 yet.

Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.

This ingredient has emollient and emulsifying properties.

As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.

As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.

This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.

Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.

We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.

Some other names for this ingredient include soy lecithin and deoiled soy lecithin.

Learn more about Lecithin

Polysilicone-11 is a type of silicone.

Preservative

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Learn more about Potassium Sorbate
Absorbent, Abrasive

Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.

Silica is often used for absorption and can help reduce shine when products are applied. Silica occurs in naturally in materials like clay and sandstone, and it can also be produced synthetically.

Silica is present naturally within the skin during collagen production and when reducing inflammation.

Learn more about Silica

When to use

11 Routines
36% use in am
64% use in pm
82% use every day
42 Routines
71% use in am
29% use in pm
95% use every day
When to use See routines that use it ->