Real Barrier Extreme Cream Ampoule Versus Numbuzin No.1 Pantothenic B5 Active Soothing Serum
Updated on August 20, 2024
Overview
What they are
These products are both reef safe . They have a total of 13 ingredients in common
Cool Features
They both contain hyaluronic acid
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing and dark spots
Free From
They both do not contain any harsh alcohols, parabens or sulfates
What's Inside
They both contain fragrances and oils
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Real Barrier Extreme Cream Ampoule 56 ingredients
Numbuzin No.1 Pantothenic B5 Active Soothing Serum 55 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
Real Barrier Extreme Cream Ampoule 56 ingredients
Numbuzin No.1 Pantothenic B5 Active Soothing Serum 55 ingredients
Benefits
Concerns
Key Ingredients
Benefits
Ingredients Side-by-side
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinDipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.
Dipropylene Glycol helps dissolve and evenly distribute ingredients. It also helps decrease viscosity and thin out texture.
As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.
Studies show Dipropylene Glycol is considered safe to use in skincare.
Learn more about Dipropylene GlycolPolyglyceryl-10 Stearate is a skin conditioner with emollient and emulsifier properties.
It is an esther of stearic acid and Polyglycerin-10.
This ingredient may not be Malassezia folliculitis, or fungal-acne safe.
Learn more about Polyglyceryl-10 StearatePanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolHydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.
This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
This oil comes from the seeds of the desert shrub called Jojoba. It is more commonly known as jojoba oil, a non-comedogenic oil.
Jojoba oil does not contain fragrance and has many fatty-acids, making it a great soothing ingredient.
It also contains Vitamin E, a great moisturizing ingredient. Vitamin E is also an antioxidant and protects your skin against oxidative damage.
This ingredient humectant properties, meaning it helps draw moisture from the air. This helps keep your skin hydrated.
While jojoba has antibacterial properties, it is only able to kill some strains of bacteria.
Studies also show it helps in wound healing. In fact, Indigenous cultures have used jojoba as a moisturizer and to help treat burns for centuries.
Fun fact: Jojoba oil similar to natural human skin sebum, so it has a great effect on dry skin. It is also promising with helping to regulate sebum production.
Due to its fatty acid content, Jojoba oil may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.
Learn more about Simmondsia Chinensis Seed OilDipotassium Glycyrrhizate comes from licorice root.
Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.
Learn more about Dipotassium GlycyrrhizateAllantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.
Some studies have shown this ingredient can promote wound healing with higher concentrations.
Allantoin is derived from the comfrey plant but produced synthetically for cosmetic products to ensure purity.
Learn more about AllantoinHydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.
Low molecular weight HA has been shown to hydrate and increase elasticity of the skin. Increasing elasticity is also associated with reduction of wrinkle depth.
One study found topical low molecular weight hyaluronic acid may be considered for the treatment of rosacea in the adult population. However, we always recommend speaking with a professional about your skin concerns.
Hyaluronic acids are a humectant. This means they draw moisture from the air. Hyaluronic acids help moisturize, soothe, and protect the skin.
Read more about other common forms of hyaluronic acid:
Learn more about Hydrolyzed Hyaluronic AcidSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium Hyaluronate1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Ingredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Real Barrier Extreme Cream Ampoule 56 ingredients
Numbuzin No.1 Pantothenic B5 Active Soothing Serum 55 ingredients

Reviews
Here's what our community thinks
Real Barrier Extreme Cream Ampoule 56 ingredients
Numbuzin No.1 Pantothenic B5 Active Soothing Serum 55 ingredients
I gave into the hype and it just ok for me! I will definitely use it up but I haven’t notice much of a difference in my skin. I also feel like she’s ran thru even though I haven’t had her that long. It’s light yet hydrating. I don’t think I’d repurchase again. I have other serums that I like better. :)