Holika Holika Cerabarrier Moisture Active Cream In Serum
A moisturizer with 110 ingredients, including exfoliants, vitamin E, and hyaluronic acid.
Overview
What it is
General moisturizer with 110 ingredients that contains ceramides, exfoliants, hyaluronic acid, peptides and Vitamin E
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin, scar healing and dark spots
Free From
It doesn't contain any harsh alcohols, parabens or sulfates
Fun facts
Holika Holika is from South Korea. This product is used in 2 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningButylene Glycol
HumectantGlycerin
HumectantButylene Glycol Dicaprylate/Dicaprate
EmollientCyclopentasiloxane
Emollient1,2-Hexanediol
Skin ConditioningC14-22 Alcohols
Emulsion StabilisingHydrogenated Polyisobutene
EmollientPentaerythrityl Tetraethylhexanoate
EmollientCetearyl Alcohol
EmollientCaprylic/Capric Triglyceride
MaskingPolyglyceryl-3 Distearate
EmulsifyingLimnanthes Alba Seed Oil
Skin ConditioningCeramide NP
Skin ConditioningBeta-Sitosterol
Emulsion StabilisingC12-20 Alkyl Glucoside
EmulsifyingBetaine
HumectantCeramide AP
Skin ConditioningCeramide As
Skin ConditioningCeramide Ng
Skin ConditioningCeramide EOP
Skin ConditioningGlyceryl Stearate
EmollientHydrogenated Lecithin
EmulsifyingCocos Nucifera Oil
MaskingAloe Barbadensis Leaf Extract
EmollientCarbomer
Emulsion StabilisingEthylhexyl Isononanoate
EmollientDimethicone
EmollientPolyquaternium-51
Skin ConditioningAmmonium Acryloyldimethyltaurate/Vp Copolymer
Palmitic Acid
EmollientSimmondsia Chinensis Seed Oil
EmollientAllantoin
Skin ConditioningStearyl Citrate
EmollientPhytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate
Skin ConditioningTromethamine
BufferingGlyceryl Polymethacrylate
Stearic Acid
CleansingHydroxypropyl Bispalmitamide Mea
EmollientGlycine Soja Sterols
EmollientTocopheryl Acetate
AntioxidantMeadowfoam Estolide
Skin ConditioningEthylhexylglycerin
Skin ConditioningHydrogenated Polydecene
EmollientCetearyl Glucoside
EmulsifyingDisodium EDTA
Theobroma Cacao Extract
Skin ConditioningDextrin
AbsorbentSodium Hyaluronate
HumectantDipropylene Glycol
HumectantColour
Sodium PCA
HumectantLinoleic Acid
CleansingSodium Lactate
BufferingAleuritic Acid
Skin ConditioningGlycosphingolipids
EmollientButyrospermum Parkii Butter
Skin ConditioningCeteareth-20
CleansingGlyceryl Citrate/Lactate/Linoleate/Oleate
EmulsifyingLecithin
EmollientSucrose Stearate
EmollientCarthamus Tinctorius Seed Oil
MaskingYeast Extract
Skin ConditioningArginine
MaskingHydroxyethyl Urea
HumectantAspartic Acid
MaskingPCA
HumectantGlycoproteins
Skin ConditioningGlycine
BufferingAlanine
MaskingSerine
MaskingValine
MaskingGlucose
HumectantDipotassium Glycyrrhizate
HumectantThreonine
Proline
Skin ConditioningIsoleucine
Skin ConditioningHistidine
HumectantPhenylalanine
MaskingMagnesium PCA
HumectantCopper Tripeptide-1
Skin ConditioningSucrose
HumectantCalcium Chloride
AstringentSea Salt
AbrasiveMagnesium Chloride
Dipotassium Phosphate
BufferingLysine
Skin ConditioningLeucine
Skin ConditioningTyrosine
MaskingMagnesium Citrate
Skin ConditioningGlucosamine Hcl
Glutamic Acid
Humectant1-Methylhydantoin-2-Imide
Skin ConditioningAsparagine
MaskingCitrulline
Skin ConditioningMethionine
Skin ConditioningTaurine
BufferingTryptophan
MaskingFormic Acid
PreservativeGlutamine
Skin ConditioningCysteine
AntioxidantLavandula Angustifolia Oil
MaskingGeranium Maculatum Oil
MaskingCitrus Grandis Peel Oil
MaskingLemongrass Oil
Citrus Aurantium Dulcis Peel Oil
MaskingParfum
MaskingMatricaria Recutita Flower Oil
PerfumingLimonene
PerfumingLinalool
PerfumingWater, Butylene Glycol, Glycerin, Butylene Glycol Dicaprylate/Dicaprate, Cyclopentasiloxane, 1,2-Hexanediol, C14-22 Alcohols, Hydrogenated Polyisobutene, Pentaerythrityl Tetraethylhexanoate, Cetearyl Alcohol, Caprylic/Capric Triglyceride, Polyglyceryl-3 Distearate, Limnanthes Alba Seed Oil, Ceramide NP, Beta-Sitosterol, C12-20 Alkyl Glucoside, Betaine, Ceramide AP, Ceramide As, Ceramide Ng, Ceramide EOP, Glyceryl Stearate, Hydrogenated Lecithin, Cocos Nucifera Oil, Aloe Barbadensis Leaf Extract, Carbomer, Ethylhexyl Isononanoate, Dimethicone, Polyquaternium-51, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Palmitic Acid, Simmondsia Chinensis Seed Oil, Allantoin, Stearyl Citrate, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Tromethamine, Glyceryl Polymethacrylate, Stearic Acid, Hydroxypropyl Bispalmitamide Mea, Glycine Soja Sterols, Tocopheryl Acetate, Meadowfoam Estolide, Ethylhexylglycerin, Hydrogenated Polydecene, Cetearyl Glucoside, Disodium EDTA, Theobroma Cacao Extract, Dextrin, Sodium Hyaluronate, Dipropylene Glycol, Colour, Sodium PCA, Linoleic Acid, Sodium Lactate, Aleuritic Acid, Glycosphingolipids, Butyrospermum Parkii Butter, Ceteareth-20, Glyceryl Citrate/Lactate/Linoleate/Oleate, Lecithin, Sucrose Stearate, Carthamus Tinctorius Seed Oil, Yeast Extract, Arginine, Hydroxyethyl Urea, Aspartic Acid, PCA, Glycoproteins, Glycine, Alanine, Serine, Valine, Glucose, Dipotassium Glycyrrhizate, Threonine, Proline, Isoleucine, Histidine, Phenylalanine, Magnesium PCA, Copper Tripeptide-1, Sucrose, Calcium Chloride, Sea Salt, Magnesium Chloride, Dipotassium Phosphate, Lysine, Leucine, Tyrosine, Magnesium Citrate, Glucosamine Hcl, Glutamic Acid, 1-Methylhydantoin-2-Imide, Asparagine, Citrulline, Methionine, Taurine, Tryptophan, Formic Acid, Glutamine, Cysteine, Lavandula Angustifolia Oil, Geranium Maculatum Oil, Citrus Grandis Peel Oil, Lemongrass Oil, Citrus Aurantium Dulcis Peel Oil, Parfum, Matricaria Recutita Flower Oil, Limonene, Linalool
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinThis is a lightweight diester (caprylic/capric acid + butylene glycol) with emollient and skin conditioning properties.
According to a manufacturer, this ingredient can help add a "cushiony" oil phase without making it heavy.
Cyclopentasiloxane, or D5, is a silicone used to improve texture of products and trap moisture.
D5 is considered lightweight and volatile. Volatile means it evaporates quickly after application. Once evaporated, D5 leaves a thin barrier that helps keep skin hydrated.
It is also an emollient. Emollients help soften the skin and prevent water loss. Silicones create a silky texture in products. D5 helps other ingredients become more spreadable.
Studies show D5 is safe to use in skincare products. We recommend speaking with a skincare professional if you have concerns.
Learn more about Cyclopentasiloxane1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Ā
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesĀ
C14-22 Alcohols is made up of synthetic fatty alcohols. More specifically, these fatty alcohols contain 14 to 22 carbons in the alkyl chain.
Its main purpose is to stabilize products. As an emulsifier, it helps prevent waters and oils from separating.
Due to this ingredient having a similar composition to cetearyl alcohol, this ingredient may not be malassezia folliculitis safe. However, the risk is low and has been only shown by a single study, so SkinSort does not currently flag C14-22 Alcohols as a fungal acne trigger.
Learn more about C14-22 AlcoholsHydrogenated Polyisobutene is a synthetic polymer. Polymers are compounds with high molecular weight. Hydrogenated Polyisobutene is an emollient and texture enhancer.
In one study, Hydrogenated Polyisobutene showed better skin hydration levels than Caprylic/Capric Triglyceride. As an emollient, it helps keep your skin soft and hydrated by trapping moisture in.
Hydrogenated Polyisobutene is often used as a mineral oil replacement.
Learn more about Hydrogenated PolyisobutenePentaerythrityl Tetraethylhexanoate is an emollient that helps make your skin smooth and hydrated. It specializes in creating a non-oily and "wet" feeling on skin.
This ingredient comes from isostearic acid, a saturated fatty acid. It is a synthetic ingredient.
Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
Learn more about Cetearyl AlcoholThis ingredient is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid. Though it behaves like an oil, it is not technically one due to its chemical composition. It is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Be sure to patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredientās final chemical composition and not its marketing name or source.
Learn more about Caprylic/Capric TriglyceridePolyglyceryl-3 Distearate isn't fungal acne safe.
Limnanthes Alba Seed Oil is the oil extracted from the seeds of the meadowfoam plant. This oil is non-fragrant and is an emollient. As an emollient, meadowfoam seed oil helps soften and hydrate the skin.
Meadowfoam seed oil is stable and has a long shelf life due to its chemical structure. It has the highest concentration of stable fatty-acids among plant oils, preventing it from degrading once exposed to oxygen.
Due to the fatty acid content, this ingredient may not be fungal-acne safe.
Meadowfoam is native to California and Oregon.
Learn more about Limnanthes Alba Seed OilCeramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Learn more about Ceramide NPBeta-Sitosterol is a plant-derived fatty acid with a structure similar to cholesterol (which naturally occurs in skin). It helps hydrate the skin and stabilize formulations.
This ingredient can be naturally found in fruits, veggies, nuts, and seeds.
We don't have a description for C12-20 Alkyl Glucoside yet.
Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. Itās known for being gentle and for helping the skin maintain balanced hydration.
Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.
Some studies suggest betaine may support making skin tone more even.
Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.
Betaine is also known as trimethylglycine.
Learn more about BetaineCeramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function.
You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has.
The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function.
Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration.
Learn more about Ceramide APCeramide AS is formally known as Ceramides 4 and 5.
Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.
Ceramide NG is a type of Ceramide. The NG stands for a sphinganine base.
Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.
Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.
If you would like to eat ceramides, sweet potatoes contain a small amount.
Read more about other common types of ceramides here:
Ceramide AP
Ceramide EOP
Ceramide NP
Ceramide EOP is formally known as Ceramide 1 and Ceramide 1 A.
EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base.
Ceramides are intercellular lipids naturally found in our skin. They bind dead skin cells together to create a barrier. The ceramides in our skin have the ability to hold water to keep our skin hydrated.
Ceramides are an important building block for our skin barrier. A strong skin barrier helps with:
If you would like to eat ceramides, sweet potatoes contain a small amount.
Read more about other common types of ceramides here:
Learn more about Ceramide EOPGlyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearateHydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Learn more about Hydrogenated LecithinThis ingredient is also known as coconut oil. It is a plant-derived ingredient with skin conditioning properties.
The fatty acid profile of coconut oil is mostly lauric acid (~54%), followed by capric, caprylic, palmitic, and myristic acids. This profile allows it to penetrate easily into skin, moisturize, and improve dry skin.
A double-blind study confirmed that extra virgin coconut oil is as effective as mineral oil for treating very dry skin. Another study found it outperformed mineral oil for mild to moderate atopic dermatitis in children.
Another study from 2018 found that virgin coconut oil can soothe inflammation and boost key skin barrier proteins. Just know this evidence is still only from lab settings and not human trials.
It has also been shown to reduce Staphylococcus aureus, a bacteria that commonly overgrows in people with eczema.
Clinical testing shows very minimal skin irritation and no evidence of sensitization or phototoxicity.
Coconut oil gets flagged as a "fragrance" because it has a natural mild scent (not because it's a synthetic perfume). The European Cosmetic ingredient database also lists "perfuming" as a function of this ingredient.
Just so you know, the term "fragrance" is completely unregulated. Some brands still use botanical extracts or essential oils in their "fragrance-free" formulas, but regulatory databases technically classify these under "fragrance".
Coconut oil has a tiny and useless bit of natural SPF. Early lab studies clocked it around SPF 7-8 but a more recent study found the real number closer to SPF 1.2. It also offers no meaningful UVA protection (SPF only overs UVB rays).
The comedogenic rating of 4/5 means it has a high potential to clog pores; but it's worth noting that comedogenicity is highly individual and ratings cannot predict how an overall formula will behave on skin.
Since lauric acid is the dominant fatty acid, this ingredient may not be fungal acne safe. The Malassezia yeast feeds on fatty acids with carbon chain lengths between 11-24, and lauric acid falls within these lengths (C12).
Learn more about Cocos Nucifera OilAloe Barbadensis Leaf Extract is an extract of the leaves of the aloe, Aloe barbadensis, Liliaceae.
Aloe is one of the most well-known natural soothing ingredients, and for good reason.Ā Itās full of water and has a cooling, calming effect on the skin, especially when itās sunburned, itchy, or irritated.Ā Aloe also helps your skin stay hydrated and smooth by mimicking what healthy skin naturally produces.Ā On top of that, it contains vitamins and nutrients that support skin recovery.Ā
It doesnāt protect you from the sun, but it can help your skin bounce back after too much time in it.
Letās get into the details:
Aloe contains antioxidant Vitamins A, C, and E, which help fight off free radicals (unstable molecules from things like pollution that can damage your skin).
Itās also rich in polysaccharides, which are natural sugars that help hydrate the skin by acting like the skinās own moisturizing agents. These, along with other sugars like monosaccharides, help form a protective barrier that locks in moisture.
Aloe works as both a humectant and an emollient. That means it draws water into the skin (humectant) and helps trap it there (emollient), making it an effective natural moisturizer.
Youāll also find a mix of other skin-supporting ingredients in aloe, including folic acid, choline, calcium, amino acids, fatty acids, and even Vitamin B12.
Out of the 420+ species of aloe, Aloe barbadensis is the most widely used in skincare products thanks to its gentle yet effective properties.
There are over 420 species of aloe but Aloe Barbadensis is the most commonly used for topical products.
Learn more about Aloe Barbadensis Leaf ExtractCarbomer is a high-molecular weight polymer of acrylic acid. It is used to form gels and thicken formulas.
Due to its large molecular size, carbomer has minimal skin penetration and is considered an inert ingredient.
A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.
Learn more about CarbomerWe don't have a description for Ethylhexyl Isononanoate yet.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconePolyquaternium-51 is a polymer salt. It helps hydrate the skin by creating a film on top. This film traps moisture in, keeping your skin soft and hydrated.
Ammonium Acryloyldimethyltaurate/Vp Copolymer is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.
Think of it as a supportive ingredient that helps your gel-creams feel silky, "cloud cream-like", and spread evenly without being greasy.
The Cosmetic Ingredient Review (CIR) Expert Panel evaluated it (along with 22 other acryloyldimethyltaurate polymers) and concluded it's:
Due to its large molecular size, it sits on the surface of skin rather than penetrating it.
Learn more about Ammonium Acryloyldimethyltaurate/Vp CopolymerPalmitic Acid is a fatty acid naturally found in our skin and in many plant and animal sources. In cosmetics, it is usually derived from palm oil. It serves many purposes in skincare, acting as a cleanser, emollient, and emulsifier.
Interestingly, topically applied Palmitic Acid can be elongated into longer chain fatty acids and ceramides. A 2019 study found low levels of Palmitic Acid lead to slower development of cells, suggesting it plays a role in keeping your skin's renewal process on track.
The CIR (Cosmetic Ingredient Review) panel determined it safe as used in cosmetics at concentrations up to 13%. It is non-irritating and non-sensitizing in clinical studies.
The culprit behind fungal acne, the Malassezia yeast, feeds on fatty acids with carbon chain lengths between C11-C24. Palmitic Acid, at C16, falls right into that sweet spot.
In vitro studies have shown that Palmitic Acid is one of the fatty acids that induce rapid Malassezia growth in lab settings.
It's worth noting that what feeds yeast in a lab doesn't necessarily feed it on your face since formulation and your skin's chemistry play a bigger role.
Learn more about Palmitic AcidJojoba oil is one of the most well-studied plant-derived ingredients in cosmetics. It is an emollient with a special structure.
Because it is made up of 97-98% wax esters, it closely mirrors the linear monoesters found in human sebum. This makes it skin compatible, non-greasy, and lightweight.
Unlike other plant oils, jojoba wax doesn't easily penetrate skin. It mostly works in the uppermost layers as an emollient. This just means it forms a light barrier on the skin to help retain moisture.
Formulations with jojoba esters up to 90% reduced transepidermal water loss (TEWL) and increased barrier recovery by 81% (outperforming bisabolol at 47%).
Besides barrier support, the science also suggests jojoba to have anti-inflammatory effects and potential applications for skin infections, aging, and wound healing.
Fun fact: Indigenous cultures have used jojoba as a moisturizer and to help treat burns for centuries.
Due to its fatty acid content, Jojoba oil may not be fungal acne safe.
Learn more about Simmondsia Chinensis Seed OilAllantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Learn more about AllantoinWe don't have a description for Stearyl Citrate yet.
Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate is an emollient ester.
As an emollient, it softens and hydrates your skin by locking moisture in. Its large, branched structure gives it a thick, cushiony feel without being greasy. This is why it shows up most often in lip balms, lipsticks, and other stick or balm formulas, where it adds gloss and helps hold waxes and pigments together.
The phytosterol portion is a nice extra. Phytosterols are plant-based lipids that are structurally similar to ones found naturally in skin, so they can help support the skin barrier.
Because this ingredient contains C16, C18, and C22 fatty chains, it may not be Malassezia/fungal acne safe. The Malassezia yeast potentially feeds on fatty acids in the C11-C24 range. If you're prone to flare-ups, you might want to patch-test or skip this one.
Learn more about Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer DilinoleateTromethamine helps balance the pH and improve the texture of a product. It is synthetically created.
As an emulsifier, Tromethamine prevents oil and water ingredients from separating. This helps stabilize the product and elongate a product's shelf life. Tromethamine also makes a product thicker.
Tromethamine helps balance the pH level of a product. Normal pH level of skin is slightly acidic (~4.75-5.5). The acidity of our skin is maintained by our glands and skin biome. Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.
Oral Tromethanmine is an anti-inflammatory drug but plays the role of masking, adding fragrance, and/or balancing pH in skincare.
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
Learn more about TromethamineThis is a synthetic polymer made by combining glycerin with polymethacrylic acid.
It is a non-drying, non-greasy moisturizer that helps enhance the feel and slip of formulations, helps stabilize emulsions, creates a film, and controls viscosity.
As a film former, it creates a light and flexible layer on the skin's surface. This helps lock in moisture without feeling heavy.
It's typically used at concentrations up to 1.9% in leave-on products. CIR has concluded that these ingredients are safe in cosmetics at current use levels.
Due to its large molecule size, it doesn't readily penetrate into skin and mostly just sits on the surface. A large UK-based patch test study of over 1,300 patients found that sensitization to related acrylate copolymers is rare.
Learn more about Glyceryl PolymethacrylateStearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.
In cosmetics, it is a multitasker:
Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.
Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.
Learn more about Stearic AcidHydroxypropyl Bispalmitamide MEA is a synthetic molecule designed to mimic ceramides. Ceramides moisturize and strengthen the skin barrier.
This ingredient is claimed to be as effective as Ceramide 3, but with the added benefits of a lower melting point. This makes it easier to work with in formulations at a more affordable price.
According to a study looking at the structure of Hydroxypropyl Bispalmitamide MEA, this ingredient cannot be categorized as a ceramide because it is lacking the sphingosine moiety.
Learn more about Hydroxypropyl Bispalmitamide MeaGlycine Soja Sterols is derived from the soybean plant. Sterols are an organic compound and technically an alcohol.
Unlike solvent alcohols, glycine soja sterols have emollient properties and help hydrate the skin.
This ingredient may not be Malassezia folliculitis, or fungal-acne safe.
Sterols can be found in plants, animals, and fungi.
Learn more about Glycine Soja SterolsTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateWe don't have a description for Meadowfoam Estolide yet.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinHydrogenated Polydecene is an emollient. It creates a non-occlusive film on the skin that offers extra protection for your skin barrier.
The texture of Hydrogenated Polydecene ranges from light and silky to rich.
Hydrogenated Polydecene is the end compound of controlled hydrogenation of Polydecene.
Learn more about Hydrogenated PolydeceneCetearyl Glucoside is a sugar-based emulsifier. It is usually made by combining cetearyl alcohol and glucose.
Belonging to the aklyl polyglucoside (APG) family, Cetearyl Glucoside has a sugar "head" that loves water and a fatty "tail" that loves oil. This means it can shuffle oil and water into a stable and smooth emulsion.
Typical use levels are between 1-5% and this ingredient is considered to be non-irritating by the CIR Expert Panel Review.
Once applied, your skin's glucoside hydrolases breaks it down to the parent fatty alcohol and glucose. This is why this ingredient may not be fungal acne safe.
Learn more about Cetearyl GlucosideDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAThis ingredient is extracted from the seeds of the cocoa tree.
Cacao seeds contain antioxidants known as polyphenols. These include flavonoids, procyanidins, and epicatechins.
Studies show these polyphenols help improve skin health.
The more famous ingredient from cocoa tree is cocoa butter.
Learn more about Theobroma Cacao ExtractDextrin is used to thicken a product and helps bind ingredients together. It is created from starch and glycogen.
As an emulsifier, dextrin prevents ingredients from separating. This helps elongate a product's shelf life.
Studies show coating UV filters with dextrin prevents these ingredients from being absorbed. This helps UV ingredients last longer on the skin.
Learn more about DextrinSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateDipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.
This ingredient helps:
Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the āgoodā alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.
As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.
Studies show Dipropylene Glycol is considered safe to use in skincare.
Learn more about Dipropylene GlycolSodium PCA is the sodium salt of pyroglutamic acid. It is naturally occurring in our skin's natural moisturizing factors where it works to maintain hydration.
The PCA stands for pyrrolidone carboxylic acid, a natural amino acid derivative.
This ingredient has skin conditioning, anti-inflammatory, and humectant properties. Humectants help hydrate your skin by drawing moisture from the air. This helps keep your skin moisturized.
Learn more about Sodium PCALinoleic Acid is also known as Vitamin F. It is a fatty acid with emollient and skin conditioning properties. Our top layer of skin, or epidermis, contains high amounts of linoleic acid naturally.
Your body uses linoleic acid to build ceramides and prostaglandins. Ceramides keep your skin's barrier hydrated and strong while prosaglandins help control inflammation and healing. Needless to say, linoleic acid is crucial for having a strong skin barrier.
One study found applying linoleic acid rich sunflower oil to be more effective at repairing the skin barrier than oleic rich olive oil.
Linoleic acid is an essential fatty acid, meaning our bodies cannot create it on its own. We need to get linoleic acid through foods such as nuts and vegetable oils.
Acne-prone skin tends to have linoleic acid and high levels of oleic acid.
Linoleic acid can also help treat acne by softening sebum to prevent clogged pores. Another study found using 2.5% linoleic acid gel for 4 weeks showed a 25% reduction in small comedones.
This ingredient can also help lighten hyperpigmentation or sun spots by disrupting the melanin production process. It also helps your skin shed melanin pigment from your skin caused by UV exposure.
Due to its role in the production of the fatty acid prostaglandin, linoleic acid can also help reduce inflammation and support wound healing.
Linoleic acid is not always fungal-acne safe; it may trigger flare-ups in sensitive individuals.
Learn more about Linoleic AcidSodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and sometimes used to adjust the pH of a product.
This ingredient is part of our skin's NMF, or natural moisturizing factor. Our NMF is essential for the hydration of our top skin layers and plasticity of skin. NMF also influences our skin's natural acid mantle and pH, which protects our skin from harmful bacteria.
High percentages of Sodium Lactate can have an exfoliating effect.
Fun fact: Sodium Lactate is produced from fermented sugar.
Learn more about Sodium LactateWe don't have a description for Aleuritic Acid yet.
Glycosphingolipids are naturally found in the cell membranes of organisms. In animals, they are the major glycolipids found.
Glyolipids help ensure the stability of cell membranes. They also help with cellular recognition, such as allowing cells to form tissues in skin.
This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.
Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).
In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).
Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.
Shea butter also contains vitamins A and E which may contribute to antioxidant activity.
While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.
This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.
Learn more about Butyrospermum Parkii ButterCeteareth-20 is an emulsifier and surfactant made by reacting cetearyl alcohol with 20 moles of ethylene oxide.
This gives it both oil and water-loving properties that makes it an effect emulsifier; it's really great at pulling oil droplets into water to create a stable, creamy, and easy-to-spread base.
Typical use ranges from 0.5-30%. Most leave-on products are in the 1-10% zone.
The 20 ethylene oxide units is well above the PEG-10 threshold and therefore not a food source for Malassezia (it's fungal acne safe).
This ingredient has a comedogenic rating of 2 and an irritancy rating of 3. These numbers come from testing the raw ingredient on rabbit ears and doesn't reflect how it will behave in a finished product.
In practice, this ingredient is a well-tolerated ingredient. The ratings reflect cautious lab conditions and not real-world use. Just be sure to patch test any formulas you feel unsure about.
Learn more about Ceteareth-20Glyceryl Citrate/Lactate/Linoleate/Oleate isn't fungal acne safe.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that causes fungal acne.
We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.
Learn more about LecithinSucrose Stearate is derived from stearic acid and sucrose (sugar). It is an emollient and emulsifier.
As an emulsifier, it prevents oils and water from separating in a product. This property also makes it a surfactant and therefore a cleansing agent.
Carthamus tinctorius seed oil comes from safflower, one of humanity's oldest crops.
Safflower seed oil contains a high percentage of linoleic acid and oleic acid. It also contains Vitamin E. These three components are effective moisturizers.
Vitamin E helps nourish your skin's lipid barrier. It is also a potent antioxidant. Antioxidants help fight free-radical molecules, or unstable molecules that may damage your skin cells.
Due to its high fatty acid content, this ingredient may not be malassezia folliculitis safe.
Thoughout history, safflower has been used for dying fabrics and in food as a saffron substitute.
Learn more about Carthamus Tinctorius Seed OilYeast extract is a silky, clear liquid derived from yeast (usually Saccharomyces cerevisiae or Torula yeast).
This ingredient has plenty of skin benefits:
Bioferments of yeast and soy have been found to reduce hyperpigmentation at low levels.
Due to its fatty acid content, this ingredient may not be fungal-acne safe.
Learn more about Yeast ExtractArginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Learn more about ArginineAspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.
Our body uses Aspartic Acid to help build collagen and elastin. It also plays a role in hydrating skin.
PCA is derived from amino acids and is naturally found in our skin's barrier.
As a humectant, PCA helps draw and hold moisture to the skin. Studies show it is effective at helping the skin stay hydrated long-term.
Glycoproteins are proteins with sugar chains attached to them. They're naturally found throughout your body, including your skin's extracellular matrix.
In your skin, glycoproteins work alongside collagen and other structural proteins to keep everything held together and functioning properly. Their sugar components make them great at binding water and keeping the skin hydrated. They also part of the extracellular matrix that plays a direct role in wound healing.
The glycoproteins found in skincare are most commonly derived from yeast, algae, or plant sources.
In-vitro studies have shown that yeast-derived glycoproteins can boost cellular oxygen content and increase energy production in skin cells.
In general, this is a well-tolerated humectant and skin conditioning ingredient. The Cosmetic Ingredient Review (CIR) Expert Panel has found no signs of irritation, adverse effects, or abnormal reactions from this ingredient.
Learn more about GlycoproteinsGlycine is the smallest amino acid and a key building block of collagen. It's part if your skin's Natural Moisturizing Factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
A study from 2022 found that an amino acid complex featuring taurine, arginine, and glycine significantly reduced skin irritation, improved redness, and accelerated the skin repair process.
Alanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.
Serine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.
Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.
Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.
Learn more about SerineValine is an essential amino acid. It is used by our bodies for tissue repair and muscle growth.
An essential amino acid is one in which our bodies cannot naturally produce so we must get them through diet. Foods such as eggs, dairy, red meat, and fish contain valine.
This ingredient can either be derived from an animal product or be synthetically created.
Learn more about ValineGlucose is a simple sugar (a monosaccharide). In skincare, it is mostly a humectant and skin conditioning agent.
Mechanistically, it has multiple hydroxyl groups that hydrogen-bond to water. This pulls moisture into the upper layers of skin to keep the surface soft and hydrated.
It's worth knowing sugars are already a natural component of the skin's NMF (natural moisturizing factor) so it's a molecule that your stratum corneum is well-acquainted with.
Just so you know, glucose is hydrophilic (water-loving) and the stratum corneum is a strong barrier to hydrophilic compounds. This just means penetration is slow and most of the action is happening on the surface.
Gram-to-gram, glucose is not as efficient as a humectant as glycerin. This is why you'll likely see glycose paired with stronger humectants for a bigger hydration payoff.
In skincare, glucose is typically derived from corn or other starch sources.
Learn more about GlucoseDipotassium Glycyrrhizate comes from licorice root.
Extracts of licorice have demonstrated to have antibacterial, antiāinflammatory, antiviral, antioxidant properties.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.
Learn more about Dipotassium GlycyrrhizateThreonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.
Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.
Proline is a non-essential amino acid, meaning your body can make it on its own. In skincare, it is a skin conditioning ingredient that keeps skin soft and hydrated.
It makes up about 23% of the collagen molecule (collagen is the protein responsible for keeping your skin firm) and is involved in your skin's natural hyaluronic acid production. When applied topically, proline can penetrate the skin fairly well due to its small molecular size.
Reviews of this ingredient have found it to be neither a dermal irritant nor a sensitizer.
Fun fact: Proline can be found in protein-rich foods like meat, fish, eggs, and dairy.
Learn more about ProlineIsoleucine is an amino acid that helps reinforce our skin barrier. This amino acid plays a role in creating protein for the body.
Fun fact: Isoleucine is found in meat, fish, dairy, legumes, and nuts.
Histidine is a semi-essential amino acid used by our bodies to create protein. It has humectant and skin conditioning properties.
Our bodies use histidine to create filaggrin - filaggrin is a structural protein that the skin uses in maintaining skin barrier.
One study found histidine and carnosine to be a dynamic duo for your skin:
Oral histidine has also been found to help with filaggrin-deficit skin disorders such as atopic dermatitis.
Why is it considered a semi-essential amino acid? This is because adults are able to create it but children must get it from their diet.
Learn more about HistidinePhenylalanine is an amino acid. It is a skin soothing and hydrating ingredient. Amino acids play a crucial role in wound healing and skin hydration.
This ingredient is also used to help even out skin tone due to its ability to disrupt the melanin production process.
Two structures of phenylalanine exist: L-phenylalanine and D-phenylalanine. L-phenylalanine is essential, this means our bodies cannot produce it naturally and we must get it from foods. Our bodies convert D-phenylalanine to neurotransmitters, and D-phenylalanine is found in our bodies naturally.
Some foods that contain L-phenylalanine include eggs, soybeans, beef, milk.
Learn more about PhenylalanineThis ingredient is the magnesium salt of PCA (Pyrrolidone Carboxylic Acid). It is a great skin hydrator for the top layers of skin.
PCA is a natural humectant, meaning it draws water from the air to your outer layer of skin.
One study found magnesium ions improved skin hydration in the outer layer of skin, or the stratum corneum. However, it did not improve TEWL, or the transepidermal water loss. The TEWL is an indicator of how healthy your skin barrier function is. This study primarily looked at healthy skin with intact skin barrier.
Learn more about Magnesium PCACopper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.
It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.
While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.
Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesnāt turn soft, barely-visible facial hairs into thick, dark ones.
Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isnāt backed by large-scale studies.
Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.
For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.
After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.
While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.
Read more about other common types of peptides here:
Learn more about Copper Tripeptide-1Sucrose is a natural sugar found in fruits, vegetables, and nuts. It is the main constituent of white sugar.
In skincare, sucrose is a humectant and can be a mild exfoliant.
Sucrose is hydrophilic, meaning it attracts water. This makes it an effective humectant and helps hydrate the skin.
Studies show sugars may worsen acne-prone skin due to it disrupting the skin's natural biome. We recommend speaking with a professional if you have any concerns.
In some products such as body scrubs, sucrose is used as an gentle exfoliant.
The term 'sucrose' comes from the french word for sugar, 'sucre'.
Learn more about SucroseCalcium chloride is a white, odorless, crystalline solid. It is an astringent and can be used to change the viscosity of products.
This ingredient is highly soluble in water, acetic acid, and ethanol.
There are many forms of this ingredient, including monohydrate, dihydrate, tetrahydrate, and hexahydrate.
Learn more about Calcium ChlorideSea salt has abrasive or exfoliation properties. It can sensitize and dry out the skin.
Magnesium chloride is a mineral salt made from magnesium and chloride. It is mainly used to control product stability and texture in cosmetics.
This ingredient can also play a role in soothing the skin and supporting normal skin function.
Magnesium chloride is water-soluble, generally well tolerated, and does not act as a strong āactiveā ingredient on its own.
Learn more about Magnesium ChlorideDipotassium Phosphate is an inorganic salt. This just means it has a different structure than organic salts. It is a stabilizing and pH adjusting ingredient.
This ingredient is soluble in water.
Lysine is an essential amino acid (your body cannot make it on its own). It has skin conditioning properties and one of the key players in collagen synthesis.
When your body creates collagen, lysine is basically the glue that holds everything together. It helps collagen fibers lock into each other and stay strong, with vitamin C being its trusty sidekick. Without enough lysine, this glue gets flimsy and less firm, resulting in less bouncy skin.
In skincare, lysine is mostly there to help keep your skin moisturized. It carries water through your skin's layers so everything stays plump.
So will putting lysine on your face create bouncier skin?
It's hard to say; most of the exciting collagen research on lysine comes from oral supplements or lab studies on mice. Further research is needed to truly understand what role topical lysine plays in skincare and your skin.
However, there's no harm in adding lysine to your routine as a supportive and hydrating ingredient.
Learn more about LysineWe don't have a description for Leucine yet.
Tyrosine is one of the amino acids used to create protein. It plays a role in melanin production.
A study from 2012 found tyrosine to show promising results in restoring skin volume.
We don't have a description for Magnesium Citrate yet.
We don't have a description for Glucosamine Hcl yet.
Glutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.
In cosmetics, glutamic acid is a famous humectant. It draws water from the air to your skin, keeping your skin hydrated (like hyaluronic acid).
An in-vitro study from 2024 found glutamic acid to play a role in inhibiting inflammation and thus a potential skin-soothing ingredient.
Other studies show it to be have potential wound healing, skin barrier repair, and hair growth properties.
Glutamic acid has poor solubility in water and other solvents.
Learn more about Glutamic AcidWe don't have a description for 1-Methylhydantoin-2-Imide yet.
Asparagine is one building block of all proteins in our body. It is an antioxidant and may help with anti-aging.
Antioxidants help fight free-radicals, or molecules that may damage our skin cells.
We don't have a description for Citrulline yet.
Methionine is an essential amino acid. It is a conditioning agent and commonly found in both skin and hair products.
This amino acid is a precursor to glutathione, a powerful antioxidant.
Fun fact: Methionine can be found in meat, fish, and dairy. It cannot be naturally produce and requires dietary intake.
Learn more about MethionineTaurine is an amino acid that is found in human skin as an osmolyte. An osmolyte is a small molecule that cells use to hold onto water and stay comfortable under stressful conditions.
In skin cell studies, taurine accumulation helps cells maintain hydration in low-humidity environments. Some dermatology research on osmolytes also link taurine to barrier support. Research also suggests that osomolyte systems can be disrupted in photoaged skin.
One animal study reported tropical taurine improved barrier function and collagen signaling, while another one found oral taurine can lessen UVB-related damage. It is important to note that evidence for taurine in skincare is mostly preclinical, meaning further studies are needed.
Learn more about TaurineWe don't have a description for Tryptophan yet.
Formic Acid is a preservative.
Glutamine is an amino acid (a small building block your body uses to make proteins). It has skin conditioning properties and helps skin feel comfortable.
Think of glutamine as a quiet support player in your skincare. Your skinās outer layer (stratum corneum) needs two things to stay healthy: a strong barrier and enough moisture.
Part of what helps hold water in the skin is something called Natural Moisturizing Factors (NMF). These include amino acids or the same building blocks that make up proteins in your body.
Since glutamine is an amino acid, it falls into the ābarrier-friendly, skin-conditioningā category. Thatās why youāll usually find it in hydrating and soothing formulas.
There's some experimental evidence that glutamine can calm inflammation-related skin reactions when applied topically in a contact-dermatitis model. However, it's not the same as a proven eczema fix.
Learn more about GlutamineCysteine is an amino acid found in our bodies. It becomes an antioxidant when converted into gluthatione.
Once it becomes gluthatione, it prevents oxidative damage to parts of our cell. Gluthatione has also been shown to protect our skin from UV-B induced damage.
Lavandula Angustifolia Oil is more commonly known as lavender essential oil. It is considered a fragrancing ingredient.
Lavender imparts a famous scent. While the smell is lovely, this ingredient and may sensitize skin in topical products. This is because about 85% of the oil is made up of linalool and linalyl acetate.
When exposed to air, these two compounds become strong allergens. This ingredient exhibits cytotoxicity at low concentrations; amounts of 0.25% have been shown to damage skin cells.
A study from Japan found this ingredient caused lavender sensitivity after widespread exposure.
Lavender essential oil has some antimicrobial, antibacterial, and anti-inflammatory properties. However, the cons of this ingredient may outweight the pros.
More research is needed to confirm lavender essential oil's effects when used in aromatherapy.
Lavandula Angustifolia is known as the English Lavender and famous for creating purple fields in Provence, France.
Learn more about Lavandula Angustifolia OilGeranium Maculatum Oil is an oil.
Citrus Grandis Peel Oil is an essential oil that is derived from the peel of a Grapefruit. It is composed largely of limonene, which is a fragrance that can cause irritation for sensitive skin.
Lemongrass Oil is an oil.
Citrus Aurantium Dulcis Peel Oil is oil from the peel of an orange fruit.
Limonene and linalool make up the majority of oils from citrus peels. Limonene has a "citrus" fragrance. Citrus peels also contain flavonoids, which have anti-inflammatory properties.
Citrus peel is also a rich source of flavonoids. Flavonoids are natural antioxidants and help protect your skin against damage. Flavonoids are a group of compounds naturally found in vegetables and fruits.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
Learn more about Citrus Aurantium Dulcis Peel OilParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of āFRAGRANCEā or āPARFUMā according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumMatricaria Recutita Flower Oil is from the german Chamomile.
Essential oils from chamomile have been found to improve wound healing due to its antimicrobial properties.
Chamomile is rich in antioxidants and has anti-inflammatory properties.
Learn more about Matricaria Recutita Flower OilLimonene is a fragrance that adds scent and taste to a formulation.
It's found in the peel oil of citrus fruits and other plants such as lavender and eucalyptus. The scent of limonene is generally described as "sweet citrus".
Limonene acts as an antioxidant, meaning it helps neutralize free radicals.
When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
Learn more about LimoneneLinalool is a fragrance and helps add scent to products. It's derived from common plants such as cinnamon, mint, citrus, and lavender.
Like Limonene, this ingredient oxidizes when exposed to air. Oxidized linalool can cause allergies and skin sensitivity.
This ingredient has a scent that is floral, spicy tropical, and citrus-like.
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