StriVectin TL Advanced™ Tightening Neck Cream PLUS Versus CKD GUARANTEED Retino Collagen Gua Sha Neck Cream
This anti-aging moisturizer is formulated around Adenosine and Acetyl Dipeptide-1 Cetyl Ester to soften the look of wrinkles.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningButyrospermum Parkii Butter
Skin ConditioningGlycerin
HumectantBis-Stearyl Dimethicone
EmollientMyristyl Nicotinate
Skin ConditioningTrimethylolpropane Tricaprylate/Tricaprate
EmollientCetearyl Alcohol
EmollientIsononyl Isononanoate
EmollientBehenyl Alcohol
EmollientPropanediol
SolventCaprylic/Capric Triglyceride
MaskingGlyceryl Stearate
EmollientOryza Sativa Bran Extract
Skin ConditioningHelianthus Annuus Extract
EmollientAdenosine
Skin ConditioningArctostaphylos Uva Ursi Leaf Extract
Skin ConditioningOryza Sativa Extract
AbsorbentRosmarinus Officinalis Leaf Extract
AntimicrobialNannochloropsis Oculata Extract
HumectantAcmella Oleracea Extract
Skin ProtectingOryza Sativa Germ Extract
EmollientAcetyl Dipeptide-1 Cetyl Ester
Skin ConditioningGlycine Soja Oil
EmollientPentapeptide-76 Amide
Butylene Glycol
HumectantAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingPolyglyceryl-3 Diisostearate
EmulsifyingSodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingCeteareth-20
CleansingSorghum Bicolor Stalk Juice
Skin ConditioningSclareolide
MaskingPentylene Glycol
Skin ConditioningTrisodium Ethylenediamine Disuccinate
Polyisobutene
Sodium Polystyrene Sulfonate
Emulsion StabilisingHydrated Silica
AbrasiveEthylhexyl Isononanoate
Emollient1,2-Hexanediol
Skin ConditioningPullulan
Caprylhydroxamic Acid
Beta-Glucan
Skin ConditioningCaprylyl Glycol
EmollientSorbitan Oleate
EmulsifyingHydroxyethylcellulose
Emulsion StabilisingCaprylyl/Capryl Glucoside
CleansingSorbitan Laurate
EmulsifyingTocopherol
AntioxidantPEG-40 Stearate
EmulsifyingParfum
MaskingAminomethyl Propanol
BufferingPotassium Sorbate
PreservativeSodium Benzoate
MaskingCitric Acid
BufferingLimonene
PerfumingWater, Butyrospermum Parkii Butter, Glycerin, Bis-Stearyl Dimethicone, Myristyl Nicotinate, Trimethylolpropane Tricaprylate/Tricaprate, Cetearyl Alcohol, Isononyl Isononanoate, Behenyl Alcohol, Propanediol, Caprylic/Capric Triglyceride, Glyceryl Stearate, Oryza Sativa Bran Extract, Helianthus Annuus Extract, Adenosine, Arctostaphylos Uva Ursi Leaf Extract, Oryza Sativa Extract, Rosmarinus Officinalis Leaf Extract, Nannochloropsis Oculata Extract, Acmella Oleracea Extract, Oryza Sativa Germ Extract, Acetyl Dipeptide-1 Cetyl Ester, Glycine Soja Oil, Pentapeptide-76 Amide, Butylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polyglyceryl-3 Diisostearate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Ceteareth-20, Sorghum Bicolor Stalk Juice, Sclareolide, Pentylene Glycol, Trisodium Ethylenediamine Disuccinate, Polyisobutene, Sodium Polystyrene Sulfonate, Hydrated Silica, Ethylhexyl Isononanoate, 1,2-Hexanediol, Pullulan, Caprylhydroxamic Acid, Beta-Glucan, Caprylyl Glycol, Sorbitan Oleate, Hydroxyethylcellulose, Caprylyl/Capryl Glucoside, Sorbitan Laurate, Tocopherol, PEG-40 Stearate, Parfum, Aminomethyl Propanol, Potassium Sorbate, Sodium Benzoate, Citric Acid, Limonene
Water
Skin ConditioningGlycerin
HumectantCaprylic/Capric Triglyceride
MaskingButylene Glycol
HumectantPentylene Glycol
Skin ConditioningNiacinamide
Smoothing1,2-Hexanediol
Skin ConditioningCetearyl Olivate
Hydrogenated Polyisobutene
EmollientSorbitan Olivate
EmulsifyingPolyglyceryl-3 Methylglucose Distearate
EmulsifyingVinyldimethicone
Diisostearyl Malate
EmollientGlyceryl Stearate
EmollientCaprylyl Methicone
Skin ConditioningErythritol
HumectantCetearyl Alcohol
EmollientGlucose
HumectantChlorella Vulgaris Extract
Skin ConditioningCarbomer
Emulsion StabilisingAmmonium Acryloyldimethyltaurate/Vp Copolymer
Fructooligosaccharides
HumectantFructose
HumectantCitrus Aurantium Bergamia Fruit Oil
MaskingMelia Azadirachta Flower Extract
Skin ConditioningOcimum Sanctum Leaf Extract
Skin ConditioningPalmitic Acid
EmollientEthylhexylglycerin
Skin ConditioningDipotassium Glycyrrhizate
HumectantStearic Acid
CleansingAdenosine
Skin ConditioningMelia Azadirachta Leaf Extract
Skin ConditioningLavandula Angustifolia Oil
MaskingHydrogenated Lecithin
EmulsifyingSodium Phytate
Retinal
Skin ConditioningCurcuma Longa Root Extract
AntioxidantCorallina Officinalis Extract
Skin ConditioningSalvia Sclarea Oil
MaskingHydrolyzed Collagen
EmollientCeramide NP
Skin ConditioningTheobroma Cacao Seed Extract
AntioxidantDextrin
AbsorbentGlycine
BufferingSerine
MaskingGlutamic Acid
HumectantTromethamine
BufferingDipropylene Glycol
HumectantCynanchum Atratum Extract
Skin ConditioningAspartic Acid
MaskingLeucine
Skin ConditioningAlanine
MaskingLysine
Skin ConditioningArginine
MaskingTyrosine
MaskingPhenylalanine
MaskingProline
Skin ConditioningValine
MaskingThreonine
Isoleucine
Skin ConditioningHistidine
HumectantMethionine
Skin ConditioningCysteine
AntioxidantHyaluronic Acid
HumectantAlthaea Rosea Flower Extract
Skin ConditioningTocopherol
AntioxidantCaprylyl/Capryl Glucoside
CleansingHexapeptide-2
BleachingHydrolyzed Elastin
EmollientBiotin
AntiseborrhoeicLimonene
PerfumingLinalool
PerfumingWater, Glycerin, Caprylic/Capric Triglyceride, Butylene Glycol, Pentylene Glycol, Niacinamide, 1,2-Hexanediol, Cetearyl Olivate, Hydrogenated Polyisobutene, Sorbitan Olivate, Polyglyceryl-3 Methylglucose Distearate, Vinyldimethicone, Diisostearyl Malate, Glyceryl Stearate, Caprylyl Methicone, Erythritol, Cetearyl Alcohol, Glucose, Chlorella Vulgaris Extract, Carbomer, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Fructooligosaccharides, Fructose, Citrus Aurantium Bergamia Fruit Oil, Melia Azadirachta Flower Extract, Ocimum Sanctum Leaf Extract, Palmitic Acid, Ethylhexylglycerin, Dipotassium Glycyrrhizate, Stearic Acid, Adenosine, Melia Azadirachta Leaf Extract, Lavandula Angustifolia Oil, Hydrogenated Lecithin, Sodium Phytate, Retinal, Curcuma Longa Root Extract, Corallina Officinalis Extract, Salvia Sclarea Oil, Hydrolyzed Collagen, Ceramide NP, Theobroma Cacao Seed Extract, Dextrin, Glycine, Serine, Glutamic Acid, Tromethamine, Dipropylene Glycol, Cynanchum Atratum Extract, Aspartic Acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Proline, Valine, Threonine, Isoleucine, Histidine, Methionine, Cysteine, Hyaluronic Acid, Althaea Rosea Flower Extract, Tocopherol, Caprylyl/Capryl Glucoside, Hexapeptide-2, Hydrolyzed Elastin, Biotin, Limonene, Linalool
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCaprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideThis ingredient is a mild surfactant made by sticking glucose onto a blend of fatty acids.
It does two jobs because it has a sugar head that loves water and a fatty tail that loves oil:
Typical use levels range from 10-20% in cleansers and 15-30% in shower products.
Once on your skin, your skin's glucoside hydrolases breaks it down into glucose and the parent fatty alcohols.
This ingredient is considered fungal acne safe because its fatty alcohol portion sits outside the Malassezia yeast's metabolization range.
Learn more about Caprylyl/Capryl GlucosideCetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Learn more about Cetearyl AlcoholGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinGlyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearateLimonene is a fragrance that adds scent and taste to a formulation.
It's found in the peel oil of citrus fruits and other plants such as lavender and eucalyptus. The scent of limonene is generally described as "sweet citrus".
Limonene acts as an antioxidant, meaning it helps neutralize free radicals.
When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
Learn more about LimonenePentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolTocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water