Versus

Peter Thomas Roth Peptide 21 Wrinkle Resist Serum Versus Drunk Elephant A-Passioni Retinol Cream

Serum
Facial Treatment
American Brand
American Brand

Updated on February 06, 2025

Overview

What they are

These products are both reef safe . They have a total of 12 ingredients in common

Cool Features

They both contain hyaluronic acid, peptides, retinoid, Vitamin C and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, common allergens or parabens

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Peptide 21 Wrinkle Resist Serum

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Rosa Centifolia Flower Water

Skin Conditioning

Isopropyl Myristate

Emollient
3-5 / 3 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Mannitol

Humectant
Helps hydrate Dry Skin Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Natto Gum

Tripeptide-10 Citrulline

Skin Conditioning
Peptide Icon

Acetyl Octapeptide-3

Humectant
Peptide IconHelps with Anti-Aging Icon

Palmitoyl Hexapeptide-12

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Acetyl Tetrapeptide-11

Skin Conditioning
Peptide Icon

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging Icon

Acetyl Hexapeptide-1

Skin Conditioning
Peptide Icon

Palmitoyl Oligopeptide

Cleansing
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Acetyl Tetrapeptide-9

Skin Conditioning
Peptide Icon

Acetyl Tetrapeptide-2

Skin Conditioning
Peptide Icon

Tripeptide-1

Skin Conditioning
Peptide IconHelps with Anti-Aging Icon

Palmitoyl Tetrapeptide-7

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Hexapeptide-11

Skin Conditioning
Peptide Icon

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Skin Conditioning
Peptide IconHelps with Anti-Aging Icon

Palmitoyl Tripeptide-5

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Trifluoroacetyl Tripeptide-2

Skin Conditioning
Peptide Icon

Palmitoyl Tripeptide-1

Skin Conditioning
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Sodium Polyglutamate

Humectant

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Retinyl Palmitate

Skin Conditioning
1-3 / 1-3 Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconNot safe for Fungal Acne IconMay worsen Rosacea Icon

Ascorbic Acid

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon

Hydrolyzed Soy Protein

Humectant
Helps hydrate Dry Skin Icon

Hydrolyzed Wheat Protein

Skin Conditioning

Lecithin

Emollient
Helps hydrate Dry Skin Icon

Pseudoalteromonas Ferment Extract

Humectant
Not safe for Fungal Acne Icon

Acrylates Copolymer

Magnesium Chloride

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Dimethyl Isosorbide

Solvent

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Leuconostoc/Radish Root Ferment Filtrate

Antimicrobial
Not safe for Fungal Acne Icon

PEG-8 Dimethicone

Emulsifying
Silicon Icon

Disodium Phosphate

Buffering

Carbomer

Emulsion Stabilising
1 / 0

Dextran

Helps hydrate Dry Skin Icon

Sodium Lactate

Buffering

Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate

Skin Conditioning

Xanthan Gum

Emulsifying

Triethanolamine

Buffering
2 / 0

Sodium Phosphate

Buffering

Octyldodecanol

Emollient

Silica

Abrasive
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon

Sodium Propoxyhydroxypropyl Thiosulfate Silica

Sulfate Icon

Sodium Hydroxide

Buffering

Caprylyl Glycol

Emollient

Potassium Sorbate

Preservative
Preservative Icon

Sodium Benzoate

Masking
Preservative Icon

Phenoxyethanol

Preservative
Preservative Icon
A-Passioni Retinol Cream

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Coco-Caprylate

Emollient
Helps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Stearic Acid

Cleansing
2-3 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Coconut Alkanes

Emollient
Not safe for Fungal Acne Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Pentylene Glycol

Skin Conditioning

Passiflora Edulis Seed Oil

Emollient
Oil IconNot safe for Fungal Acne Icon

Retinol

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Simmondsia Chinensis Seed Oil

Emollient
0-2 / 0 Oil IconHelps hydrate Dry Skin IconGood for Scar Healing IconNot safe for Fungal Acne Icon

Sclerocarya Birrea Seed Oil

Humectant
Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Prunus Armeniaca Kernel Oil

Masking
1-2 / 0 Oil IconNot safe for Fungal Acne Icon

Cetyl Ethylhexanoate

Emollient

Palmitoyl Tripeptide-1

Skin Conditioning
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Palmitoyl Tetrapeptide-7

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Brassica Oleracea Acephala Leaf Extract

Humectant

Brassica Oleracea Italica Extract

Astringent

Tetrahexyldecyl Ascorbate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Chrysin

Skin Conditioning

Persea Gratissima Oil

Skin Conditioning
0-3 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Linoleic Acid

Cleansing
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Linolenic Acid

Cleansing
Fragrance IconHelps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconNot safe for Fungal Acne Icon

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Xanthophylls

Skin Conditioning

Phytosphingosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Phytosterols

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Jojoba Esters

Emollient
Not safe for Fungal Acne Icon

Physalis Pubescens Fruit Juice

Skin Conditioning

Stearyl Glycyrrhetinate

Skin Conditioning

Oryza Sativa Extract

Absorbent
Helps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing Icon

Glycine Soja Oil

Emollient
3 / 0 Oil IconHelps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Carthamus Tinctorius Seed Oil

Masking
0-2 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Palmitoyl Hexapeptide-12

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Cetyl Palmitate

Emollient
0 / 0 Not safe for Fungal Acne Icon

Trehalose

Humectant
Helps hydrate Dry Skin Icon

Lauric Acid

Cleansing
4 / 1 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Sodium Hyaluronate Crosspolymer

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconGood for Scar Healing Icon

Olea Europaea Fruit Oil

Masking
0-2 / 0 Fragrance IconOil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Glucosamine Hcl

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Coco-Caprylate/Caprate

Emollient
Not safe for Fungal Acne Icon

Pisum Sativum Extract

Skin Conditioning

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Bambusa Vulgaris Leaf/Stem Extract

Humectant

Phenoxyethanol

Preservative
Preservative Icon

Caprylyl Glycol

Emollient

Carbomer

Emulsion Stabilising
1 / 0

Trideceth-6 Phosphate

Emulsifying

N-Hydroxysuccinimide

Skin Conditioning

Ceteareth-20

Cleansing
2 / 3 May worsen Oily Skin Icon

Sodium Hydroxide

Buffering

Laureth-23

Cleansing
3 / 0

Steareth-20

Cleansing
2 / 1

Propanediol

Solvent
Helps hydrate Dry Skin Icon

Chlorhexidine Digluconate

Antimicrobial
Preservative Icon

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Trisodium Ethylenediamine Disuccinate

Chlorphenesin

Antimicrobial
Preservative Icon

Potassium Sorbate

Preservative
Preservative Icon

Ethylhexylglycerin

Skin Conditioning

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Skin Conditioning

Palmitoyl Hexapeptide-12 is a synthetic peptide made with glycine, histidine, lysine, and palmitic acid.

The sequence of this peptide matches that of elastin, a key protein that plays a role in how firm our skin is.

Due to its palmitic acid base, this ingredient may not be fungal-acne safe.

Learn more about Palmitoyl Hexapeptide-12
Skin Conditioning

Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.

This ingredient consists of four amino acids and palmitic acid. These amino acids are arginine, proline, glutamine, and glycine.

This ingredient has many benefits. These benefits include boosting collagen production, fighting inflammation, and reversing UV damage.

By preventing our bodies from producing interleukins, Palmitoyl Tetrapeptide-7 helps fight inflammation. An interleukin is a chemical that signals to the body to produce an inflammatory response. Interleukin production is accelerated by UV radiation.

Palmitoyl Tetrapeptide-7 tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.

Read more about other common types of peptides here:

Learn more about Palmitoyl Tetrapeptide-7
Skin Conditioning

Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.

This ingredient is a signal peptide, meaning it tells our skin to create collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.

Palmitoyl Tripeptide-1 can help reduce wrinkles and make the skin look more youthful.

Read more about other common types of peptides here:

Learn more about Palmitoyl Tripeptide-1
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Emulsifying

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.

Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.

The lauric acid used to create Polysorbate 20 is often derived from coconuts.

Polysorbate 20 may not be fungal acne safe.

Learn more about Polysorbate 20
Preservative

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Learn more about Potassium Sorbate
Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Learn more about Sodium Hydroxide
Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

19 Routines
53% use in am
47% use in pm
89% use every day
143 Routines
7% use in am
93% use in pm
59% use every day
When to use See routines that use it ->

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