Nacific Rice + Pepta Collagen Glow Bouncy Cream
A moisturizer with 85 ingredients, including vitamin C, niacinamide, and exfoliants.
Overview
What it is
General moisturizer with 85 ingredients that contains ceramides, exfoliants, niacinamide, peptides, Vitamin C and Vitamin E
Cool Features
It is vegan, cruelty-free, and reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, oils, parabens or sulfates
Fun facts
Nacific is from South Korea.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningGlycerin
HumectantSqualane
EmollientCaprylic/Capric Triglyceride
MaskingNiacinamide
SmoothingPentylene Glycol
Skin ConditioningPolyglycerin-3
HumectantVinyldimethicone
1,2-Hexanediol
Skin ConditioningCetearyl Alcohol
EmollientButylene Glycol Dicaprylate/Dicaprate
EmollientDiglycerin
HumectantPolyglyceryl-3 Methylglucose Distearate
EmulsifyingButyrospermum Parkii Butter
Skin ConditioningChlorella Vulgaris Extract
Skin ConditioningCoptis Japonica Root Extract
Skin ConditioningTheobroma Cacao Extract
Skin ConditioningOryza Sativa Extract
AbsorbentCynanchum Atratum Extract
Skin ConditioningSea Salt
AbrasiveAvena Sativa Peptide
Skin ConditioningSaccharomyces/Rice Ferment Filtrate
Skin ConditioningBifida Ferment Extract
HumectantAlthaea Rosea Flower Extract
Skin ConditioningSoluble Collagen
HumectantAspergillus Ferment
Skin ConditioningHydrolyzed Rice Protein
Skin ConditioningRice Amino Acids
Skin ConditioningDimethicone
EmollientHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingBetaine
HumectantGlyceryl Stearate
EmollientMethyl Hydrogenated Rosinate
PerfumingPanthenol
Skin ConditioningPolyglyceryl-3 Distearate
EmulsifyingHydrogenated Lecithin
EmulsifyingAmmonium Acryloyldimethyltaurate/Vp Copolymer
Silica
AbrasiveSodium Polyacryloyldimethyl Taurate
Emulsion StabilisingHydrogenated Polydecene
EmollientGlucose
HumectantButylene Glycol
HumectantDimethiconol
EmollientPalmitic Acid
EmollientEthylhexylglycerin
Skin ConditioningFructooligosaccharides
HumectantFructose
HumectantStearic Acid
CleansingAdenosine
Skin ConditioningSorbitan Isostearate
EmulsifyingAllantoin
Skin ConditioningDipotassium Glycyrrhizate
HumectantSodium Phytate
Glyceryl Stearate Citrate
EmollientTrideceth-10
CleansingGlyceryl Acrylate/Acrylic Acid Copolymer
HumectantSodium Polyacrylate
AbsorbentDextrin
AbsorbentTocopherol
AntioxidantCeramide NP
Skin ConditioningSucrose Stearate
EmollientSorbitan Laurate
EmulsifyingCholesterol
EmollientHydroxyethylcellulose
Emulsion StabilisingAcetyl Dipeptide-1 Cetyl Ester
Skin ConditioningCeramide Ns
Skin ConditioningGlycosphingolipids
EmollientPhytosphingosine
Skin ConditioningCeramide AP
Skin ConditioningCeramide As
Skin ConditioningAcetyl Hexapeptide-8
HumectantAscorbic Acid Polypeptide
AntioxidantCeramide EOP
Skin ConditioningAcetyl Octapeptide-3
HumectantAcetyl Tetrapeptide-2
Skin ConditioningAcetyl Tetrapeptide-3
Skin ProtectingAcetyl Tetrapeptide-5
HumectantAcetyl Tetrapeptide-9
Skin ConditioningCarnosine
Skin ConditioningCopper Tripeptide-1
Skin ConditioningNonapeptide-1
Skin ConditioningPalmitoyl Pentapeptide-4
Skin ConditioningPalmitoyl Tripeptide-1
Skin ConditioningPalmitoyl Tripeptide-5
Skin ConditioningXanthan Gum
EmulsifyingWater, Glycerin, Squalane, Caprylic/Capric Triglyceride, Niacinamide, Pentylene Glycol, Polyglycerin-3, Vinyldimethicone, 1,2-Hexanediol, Cetearyl Alcohol, Butylene Glycol Dicaprylate/Dicaprate, Diglycerin, Polyglyceryl-3 Methylglucose Distearate, Butyrospermum Parkii Butter, Chlorella Vulgaris Extract, Coptis Japonica Root Extract, Theobroma Cacao Extract, Oryza Sativa Extract, Cynanchum Atratum Extract, Sea Salt, Avena Sativa Peptide, Saccharomyces/Rice Ferment Filtrate, Bifida Ferment Extract, Althaea Rosea Flower Extract, Soluble Collagen, Aspergillus Ferment, Hydrolyzed Rice Protein, Rice Amino Acids, Dimethicone, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Betaine, Glyceryl Stearate, Methyl Hydrogenated Rosinate, Panthenol, Polyglyceryl-3 Distearate, Hydrogenated Lecithin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Silica, Sodium Polyacryloyldimethyl Taurate, Hydrogenated Polydecene, Glucose, Butylene Glycol, Dimethiconol, Palmitic Acid, Ethylhexylglycerin, Fructooligosaccharides, Fructose, Stearic Acid, Adenosine, Sorbitan Isostearate, Allantoin, Dipotassium Glycyrrhizate, Sodium Phytate, Glyceryl Stearate Citrate, Trideceth-10, Glyceryl Acrylate/Acrylic Acid Copolymer, Sodium Polyacrylate, Dextrin, Tocopherol, Ceramide NP, Sucrose Stearate, Sorbitan Laurate, Cholesterol, Hydroxyethylcellulose, Acetyl Dipeptide-1 Cetyl Ester, Ceramide Ns, Glycosphingolipids, Phytosphingosine, Ceramide AP, Ceramide As, Acetyl Hexapeptide-8, Ascorbic Acid Polypeptide, Ceramide EOP, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Acetyl Tetrapeptide-3, Acetyl Tetrapeptide-5, Acetyl Tetrapeptide-9, Carnosine, Copper Tripeptide-1, Nonapeptide-1, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Xanthan Gum
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinSqualane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, itâs technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term âoil-freeâ isnât regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Learn more about SqualaneCaprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredientâs final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamidePentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolPolyglycerin-3 is a 3-unit glycerin polymer.
Like glycerin, this ingredient is a humectant. Humectants help hydrate your skin by drawing water to it.
Having moisturized skin helps improve the skin barrier. Your skin barrier helps protect against irritants and bacteria.
Learn more about Polyglycerin-3Vinyldimethicone is a type of silicone.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Â
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesÂ
Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Learn more about Cetearyl AlcoholThis is a lightweight diester (caprylic/capric acid + butylene glycol) with emollient and skin conditioning properties.
According to a manufacturer, this ingredient can help add a "cushiony" oil phase without making it heavy.
Diglycerin is a humectant. It is derived from glycerin, which is naturally found in your skin.
As a humectant, it helps draw moisture to the skin from the air.
Polyglyceryl-3 Methylglucose Distearate is a plant-derived emulsifier whose only job is to keep the oily and watery parts of a formula blended so it doesn't separate into layers.
It's compatible with a wide-range of active ingredients and especially good at making emulsions survive heat/freeze cycles.
Typical use concentrations range from 2-3% and it works across a pH of 4.5-8.5.
This ingredient has been found safe to use in cosmetics and has a low irritation profile.
Because it's build on stearic acid, it may not be fungal acne safe. Stearic acid is a C18 fatty acid that falls within the range (C11-24) that Malassezia can feed on.
Learn more about Polyglyceryl-3 Methylglucose DistearateThis ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.
Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).
In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).
Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.
Shea butter also contains vitamins A and E which may contribute to antioxidant activity.
While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.
This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.
Learn more about Butyrospermum Parkii ButterChlorella Vulgaris Extract comes from a green microalga. It is hydrating and contains antioxidants.
Studies also show Chlorella Vulgaris may help in rebuilding collagen and elastin. This ingredient is made up of lipids, carbohydrates, and chlorophyll.
Fun fact: This ingredient is commonly used as food additive in Japan.
Learn more about Chlorella Vulgaris ExtractCoptis Japonica Root Extract, also known as Japanese Goldthread, is a traditional East Asian herb. It is prized for its anti-inflammatory, antioxidant, and antimicrobial properties.
Thatâs not all - research in the International Journal of Cosmetic Science found that its active compound, berberine, may help reduce fat accumulation and slow down fat cell development.
This makes it a promising ingredient for slimming and anti-cellulite products!
Learn more about Coptis Japonica Root ExtractThis ingredient is extracted from the seeds of the cocoa tree.
Cacao seeds contain antioxidants known as polyphenols. These include flavonoids, procyanidins, and epicatechins.
Studies show these polyphenols help improve skin health.
The more famous ingredient from cocoa tree is cocoa butter.
Learn more about Theobroma Cacao ExtractOryza Sativa Extract comes from the rice grain, Oryza sativa. Rice extract has wound healing, antioxidant, anti-inflammatory, and hydrating properties.
Rice grains contain numerous antioxidants which may help with anti-aging, such as vitamin E. Antioxidants help stabilize free-radical molecules. Unstable free-radical molecules may damage your skin cells and accelerate signs of aging.
A study from 2002 found rice to help increase the rate of wound healing. The same study found an improvement of skin barrier function in the patients after taking rice baths.
Numerous in-vitro studies have found rice water to help decrease sun damage by increasing collagen production and inhibiting the process of tyrosinase.
Long story short- tyrosinase is an enzyme that controls melanin production. Our bodies start producing melanin (AKA tanning) when exposed to UV radiation to protect against damage. Rice water is found to partially block this process.
Though more research is needed on rice's ability to help with UV protection, recent studies seem promising.
Wondering why rice is hydrating? The protein in rice have emollient properties. Emollients create a barrier on the skin to trap moisture in, keeping your skin moisturized.
Some rice extract may have mildly-exfoliating properties. These are mainly limited to Oryza Sativa (Rice) Bran and Oryza Sativa (Rice) Germ Powder.
This rice was first cultivated in China over 10,000 years ago. Many cultures throughout Asia have used rice water on skin and hair for centuries.
Learn more about Oryza Sativa ExtractWe don't have a description for Cynanchum Atratum Extract yet.
Sea salt has abrasive or exfoliation properties. It can sensitize and dry out the skin.
This peptide is extracted from oat. It has skin conditioning properties.
Peptides are great for boosting hydration.
This ingredient is created by fermenting the yeast, Saccharomyces, and rice. Saccharomyces is rich in beta-glucan and has great hydrating properties.
Rice ferment also has great skin benefits - read more about them here.
Bifida Ferment Extract is the extract from fermented Bifidobacterium.
This ingredient is a well-tolerated ingredient that can help with barrier repair, antioxidant protection, and calming reactive skin.
This ingredient comes from the hollyhock flower. It has skin conditioning properties.
Soluble collagen comes from animals and fish. It has a large molecule size, meaning it doesn't get absorbed into skin.
Instead, it sits on top of skin as a humectant to improve skin hydration. It has incredible water-binding properties and creates a water barrier on skin that prevents evaporation.
This ingredient is incredibly gentle and often used to counter more irritating ingredients.
While our skin does have collagen, this ingredient is not used by the skin for anti-aging. Applying collagen topically has not been linked to helping with collagen loss in skin. All the benefits of soluble collagen are related to hydration.
Fun fact: The name "soluble collagen" refers to its ability to dissolve in water.
Learn more about Soluble CollagenAspergillus Ferment is created when Aspergillus fungi is fermented under controlled conditions. This is the same fungi used to make sake, miso, and soy sauce.
The fungi breaks down to produce a mix of enzymes, amino acids, vitamins, and bioactive compounds during fermentation.
One such compound is kojic acid; kojic acid is widely considered a gentler alternative to hydroquinone. You should know: the amount of kojic acid in Aspergillus Ferment will vary depending on species used and how the fermentation was done.
There's an in-vitro study from 2019 found that ceramide-like compounds from Aspergillus luchuensis helped skin cells turn on the genes related to barrier repair and moisture retention. Just keep in mind this was tested on cells in a lab and not on actual people's faces.
If you're someone who deals with fungal acne (malassezia folliculitis), you might want to instinctively want to skip this ingredient.
That's understandable since it is derived from a fungus. It's worth knowing that Aspergillus and Malassezia are completely different organisms and there's no research suggesting that Aspergillus Ferment feeds or worsens malassezia overgrowth on the skin.
However, if you're actively managing fungal acne, being cautious with any new ingredient is reasonable.
Learn more about Aspergillus FermentHydrolyzed Rice Protein is protein extracted from rice. This ingredient is rich in antioxidants and peptides.
Studies show this ingredient may help with blocking the melanin creation process when skin is exposed to UV.
Rice amino acids are the amino acids you get when you fully break down rice protein. These amino acids (glutamic acid, lysine, glycine, serine) are major players in your skin's natural moisturizing factor (NMF), or your skin's built-in hydration system.
A 2021 study in Cosmetics found that these amino acids can fight free radicals and may help with skin brightening by slowing down melanin production. Another 2025 review confirmed that rice-derived amino acids and peptides help with hydration, barrier repair, and antioxidant protection.
As for fungal acne, this ingredient is generally considered low risk. This is because Malassezia is a lipid-dependent yeast that feeds primarily on fatty acids with carbon chain lengths of C11-C24, not amino acids. On its own, this ingredient doesn't provide the lipid fuel Malassezia needs to thrive.
Learn more about Rice Amino AcidsDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeThis is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.
It is also an emulsifer, meaning it prevents ingredients such as oil and water from separating. It also helps evenly disperse other ingredients.
Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. Itâs known for being gentle and for helping the skin maintain balanced hydration.
Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.
Some studies suggest betaine may support making skin tone more even.
Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.
Betaine is also known as trimethylglycine.
Learn more about BetaineGlyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearateMethyl Hydrogenated Rosinate is a fragrance.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolPolyglyceryl-3 Distearate isn't fungal acne safe.
Hydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Learn more about Hydrogenated LecithinAmmonium Acryloyldimethyltaurate/Vp Copolymer is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.
Think of it as a supportive ingredient that helps your gel-creams feel silky, "cloud cream-like", and spread evenly without being greasy.
The Cosmetic Ingredient Review (CIR) Expert Panel evaluated it (along with 22 other acryloyldimethyltaurate polymers) and concluded it's:
Due to its large molecular size, it sits on the surface of skin rather than penetrating it.
Learn more about Ammonium Acryloyldimethyltaurate/Vp CopolymerSilica, also known as silicon dioxide, is a naturally occurring mineral. It is used as a fine, spherical, and porous powder in cosmetics.
Though it has exfoliant properties, the function of silica varies depending on the product.
The unique structure of silica enhances the spreadability and adds smoothness, making it a great texture enhancer.
It is also used as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.
In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. When you rub them in, they lightly polish away dead skin layers and enhance the penetration of active ingredients.
Learn more about SilicaSodium Polyacryloyldimethyl Taurate is a polymer and used to help stabilize other ingredients.
Emulsion stabilizers hold ingredients together, helping to create an even texture throughout the product.
Sodium Polyacryloyldimethyl Taurate can also be used to thicken the texture.
Learn more about Sodium Polyacryloyldimethyl TaurateHydrogenated Polydecene is a synthetic emollient. It forms a non-occlusive film on the skin's surface to provide a silky feel without being greasy.
In vivo studies in volunteers with atopic and dry skin showed no irritation or intolerance. The volunteers also saw a positive effect in dryness, scaling, and roughness after 28 days of use.
Concentrations up to 100% in guinea pig tests found it to be non-sensitizing and completely safe for use in cosmetics.
Learn more about Hydrogenated PolydeceneGlucose is a simple sugar (a monosaccharide). In skincare, it is mostly a humectant and skin conditioning agent.
Mechanistically, it has multiple hydroxyl groups that hydrogen-bond to water. This pulls moisture into the upper layers of skin to keep the surface soft and hydrated.
It's worth knowing sugars are already a natural component of the skin's NMF (natural moisturizing factor) so it's a molecule that your stratum corneum is well-acquainted with.
Just so you know, glucose is hydrophilic (water-loving) and the stratum corneum is a strong barrier to hydrophilic compounds. This just means penetration is slow and most of the action is happening on the surface.
Gram-to-gram, glucose is not as efficient as a humectant as glycerin. This is why you'll likely see glycose paired with stronger humectants for a bigger hydration payoff.
In skincare, glucose is typically derived from corn or other starch sources.
Learn more about GlucoseButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolDimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.
This ingredient helps to create a silky texture and improve spreadability. Due to its high molecular weight and thickness, it is often combined with cyclopentasiloxane.
Palmitic Acid is a fatty acid naturally found in our skin and in many plant and animal sources.
In cosmetics, it is usually derived from palm oil. It serves many purposes in skincare, acting as a cleanser, emollient, and emulsifier.
Interestingly, topically applied Palmitic Acid can be elongated into longer chain fatty acids and ceramides. A 2019 study found low levels of Palmitic Acid lead to slower development of cells, suggesting it plays a role in keeping your skin's renewal process on track.
The CIR (Cosmetic Ingredient Review) panel determined it safe as used in cosmetics at concentrations up to 13%. It is non-irritating and non-sensitizing in clinical studies.
The culprit behind fungal acne, the Malassezia yeast, feeds on fatty acids with carbon chain lengths between C11-C24. Palmitic Acid, at C16, falls right into that sweet spot.
In vitro studies have shown that Palmitic Acid is one of the fatty acids that induce rapid Malassezia growth in lab settings.
It's worth noting that what feeds yeast in a lab doesn't necessarily feed it on your face since formulation and your skin's chemistry play a bigger role.
Learn more about Palmitic AcidEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinFructooligosaccharides (FOS) are a type of prebiotic sugar with humectant and skin conditioning properties. As a humectant, they help attract and hold moisture in the skin.
FOS essentially acts as a food source for the "good" bacteria on your skin and make it harder for "bad" bacteria to thrive. A 2022 study using a reconstructured human skin model found that just 1% of FOS was enough to shift the bacteria balance in favor of beneficial species. This suggests it could help support a healthier skin microbiome over time.
This ingredient has a low sensitization risk and testing shows it does not classify as a skin irritant or sensitizer.
FOS are usually produced from sugar beets and can also be found in foods like bananas, garlic, and onions.
Learn more about FructooligosaccharidesStearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.
In cosmetics, it is a multitasker:
Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.
Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.
Learn more about Stearic AcidAdenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.
Studies have found adenosine may also help with wound healing.
In skincare products, Adenosine is usually derived from yeast.
Learn more about AdenosineSorbitan Isostearate is an emulsifer. It is created from isostearic acid and sorbitol.
As an emulsifier, it keeps the water and oil ingredients from separating. This keeps formulas stable and smooth.
In a 24 hour occlusive patch test on 56 subjects, 10% sorbitan isostearate was completely non-irritating. Most formulas use less than 10%.
Because it's a fatty acid ester, it may not be fungal acne safe since the Malassezia yeast can utilize it as a nutrient source.
Learn more about Sorbitan IsostearateAllantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Learn more about AllantoinDipotassium Glycyrrhizate comes from licorice root.
Extracts of licorice have demonstrated to have antibacterial, antiâinflammatory, antiviral, antioxidant properties.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.
Learn more about Dipotassium GlycyrrhizateSodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.
Sodium Phytate is a chelating agent. Chelating agents help prevent metals from binding to water. This helps stabilize the ingredients and the product.
Glyceryl Stearate Citrate is a citric acid ester of glyceryl stearate.
It is an emulsifier, emollient, and a surfactant.
Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating. Common ingredients include oils and water, which do not mix naturally. Emulsifiers have properties that help keep ingredients such as these together.
Emollients help soothe and soften the skin. They do this by creating a protective film on your skin. This barrier helps trap moisture and keeps your skin hydrated. Emollients may be effective at treating dry or itchy skin.
Surfactants help gather oils, dirt, and other pollutants from the skin. This helps them to be easily rinsed away.
Learn more about Glyceryl Stearate CitrateWe don't have a description for Trideceth-10 yet.
Glyceryl Acrylate/Acrylic Acid Copolymer is made up of glycerin and polyacrylic acid. It helps hydrate your skin as a humectant.
This ingredient forms a hydrogel that delivers moisturizing, water-based ingredients to the skin. It is also used to thicken a product and to give it a smooth texture.
Acrylic acid itself is toxic, but the polymer form (this ingredient) is too large to penetrate skin, making it non-toxic.
Learn more about Glyceryl Acrylate/Acrylic Acid CopolymerSodium Polyacrylate is the sodium salt of polyacrylic acid. It is used as an absorber, emollient, and stabilizer.
This ingredient is a super-absorbent polymer - meaning it can absorb 100 to 1000 times its mass in water. As an emollient, Sodium Polyacrylate helps soften and soothe skin. Emollients work by creating a barrier to trap moisture in. This helps keep your skin hydrated.
Dextrin is used to thicken a product and helps bind ingredients together. It is created from starch and glycogen.
As an emulsifier, dextrin prevents ingredients from separating. This helps elongate a product's shelf life.
Studies show coating UV filters with dextrin prevents these ingredients from being absorbed. This helps UV ingredients last longer on the skin.
Learn more about DextrinTocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolCeramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Learn more about Ceramide NPSucrose Stearate is derived from stearic acid and sucrose (sugar). It is an emollient and emulsifier.
As an emulsifier, it prevents oils and water from separating in a product. This property also makes it a surfactant and therefore a cleansing agent.
Sorbitan Laurate is created from lauric acid and derivatives from sorbitol. It is an emulsifier.
Cholesterol is a lipid that is naturally found in human skin and is one of the three key components of your skin barrier. In skincare, it is an emollient and barrier-repairing ingredient.
It works by fitting directly into the lipid layers of skin to help restore structure and reduce transepidermal water loss (TEWL).
This is a great ingredient for dry, compromised, or aging skin; our skin starts to produce less cholesterol with age.
Research shows cholesterol works best in combination with ceramides and fatty acids, the other two major components in your skin barrier.
Cholesterol is also a well-establish penetration enhancer and can help other actives absorb more effectively.
Cosmetic-grade cholesterol is usually derived from lanolin but plant and synthetic options also exist. We recommend reaching out to the brand if you have questions about their source of cholesterol.
Learn more about CholesterolHydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.
This ingredient helps stabilize products by preventing ingredients from separating. It can also help thicken the texture of a product.
This ingredient can also be found in pill medicines to help our bodies digest other ingredients.
Learn more about HydroxyethylcelluloseAcetyl Dipeptide-1 Cetyl Ester is a peptide composed of amino acids arginine and tyrosine.
This peptide is considered a neurotransmitter peptide, meaning it has pain-relieving and relaxing properties. It has the ability to calm skin irritation from external factors such as chemical stinging or heat.
Neurotransmitter peptides are also often called "botox in a bottle". This is because these peptides have the ability to relax the muscles.
Though relaxing the muscles can prevent expression lines (as we have seen in botox), the studies do not show these peptides to be a botox replacement. The effects of this muscle relaxation is also short-term, as opposed to longer-term results from botox.
Learn more about Acetyl Dipeptide-1 Cetyl EsterCeramide NS is formally known as Ceramide 2. It is one of the major ceramides in the stratum corneum (outermost layer of skin) plays a role in forming a protective barrier.
Due to its structure, skin lipids can be packed tightly and in turn, this strengthens the barrier and reduces water loss.
Studies show conditions like atopic dermatitis can worsen when ceramide NS levels are low.
Learn more about Ceramide NsGlycosphingolipids are naturally found in the cell membranes of organisms. In animals, they are the major glycolipids found.
Glyolipids help ensure the stability of cell membranes. They also help with cellular recognition, such as allowing cells to form tissues in skin.
Phytosphingosine is a phospholipid naturally found in our skin as a building block for ceramides.. It helps moisturize, soothe, and protect skin.
Phytosphingosine contributes to your skin's natural moisturizing factor (NMF). The NMF is responsible for hydration, a strong barrier, and plasticity. Our NMF decreases with age. Increasing NMF leads to more healthy and hydrated skin.
Studies show products formulated with NMF ingredients help strengthen our skin's barrier. Having a healthy skin barrier reduces irritation and increases hydration. Our skin barrier is responsible for having plump and firm skin. It also helps protect our skin against infection, allergies, and inflammation.
Fun fact: Phytosphingosine is abundant in plants and fungi.
More ingredients that help boost collagen in skin:
Learn more about PhytosphingosineCeramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function.
You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has.
The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function.
Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration.
Learn more about Ceramide APCeramide AS is formally known as Ceramides 4 and 5.
Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.
Acetyl Hexapeptide-8, commonly known as Argireline or Acetyl Hexapeptide-3, is a popular peptide in skincare. Itâs often referred to as a âBotox-likeâ ingredient because it helps reduce muscle movement.
By relaxing these micro-movements, Argireline may help minimize the appearance of fine lines and wrinkles. That said, itâs not as powerful as Botox, and research on its long-term effectiveness is still limited.
Beyond smoothing, Argireline may also support collagen production. Collagen is the protein that helps keep your skin firm, bouncy, and well-hydrated by strengthening the skin barrier.
So while Argireline isnât a miracle fix, it can be a helpful addition to a routine focused on both prevention and skin health.
Read more about other common types of peptides here:
Learn more about Acetyl Hexapeptide-8Ascorbic Acid Polypeptide is a stable form of vitamin C that offers the same benefits with less irritation.
Read about the benefits of ascorbic acid here.
Fun fact: Ascorbic Acid Polypeptide has a similar structure to the vitamin C found in fruits.
Learn more about Ascorbic Acid PolypeptideCeramide EOP is formally known as Ceramide 1.
It is naturally found in skin and part of the intercellular "mortar" holding everything together in your outermost layer.
EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base.
What makes Ceramide EOP special is its ultra-long fatty acid chain; this unique structure allows it to bridge the lipid layers in your skin barrier to prevent water loss (something no other ceramide can do).
Low levels of Ceramide EOP have been found in people with eczema and psoriasis.
Using it together with other ceramides, cholesterol, and linoleic acid have been shown to meaningfully improve hydration and reduce water loss.
In one clinical study, a regimen using Ceramide EOP, NP, and AP led to significant symptom improvements in patients with eczema, psoriasis, and dry skin in just 4 weeks.
You'll usually see concentrations between 0.1-0.5% in formulations. Overall, this is a well-tolerated and safe ingredient for cosmetic use.
Learn more about Ceramide EOPAcetyl Octapeptide-3 is a synthetic peptide also commonly known as SNAP-8. It is a lab-made peptide often marketed as a gentler, topical alternative to Botox.
It works by mimicking part of a protein involved in muscle contractions, which may help relax facial tension and reduce the appearance of fine lines (mostly around the eyes and forehead).
Itâs considered a ânext-genâ version of Argireline (Acetyl Hexapeptide-8), an older peptide with more research behind it that also supports collagen production.
SNAP-8 showed slightly better results than Argireline in one small manufacturer-funded study, but thereâs limited independent research. Plus, most tests use concentrations higher than whatâs typically found in skincare products.
This ingredient might offer a subtle smoothing effect but it won't donât deliver the dramatic results of actual Botox injections.
Think of it more like a supporting actor in your skincare lineup.
Learn more about Acetyl Octapeptide-3This peptide is more commonly known as Thymulen 4 BG.
It is derived from a youth hormone called thymopoietin. Thymopoietin helps regulate the immune system and decreases naturally with age.
According to the manufacturer, this peptide boosts the skin's immune defenses and regenerates the outer layers of skin.
Learn more about Acetyl Tetrapeptide-2This biometic peptide is designed to support hair growth.
According to a manufacturer, it stimulates hair growth by:
The manufacturer has found combining this ingredient with red clover extract (Capixyl) boosted benefits. Not only does it enforce the scalp's extracellular matrix, it also inhibits the enzyme that creates DHT, a hormone that leads to hair loss.
While this ingredient is promising, more research is still needed to confirm its full effectiveness.
Learn more about Acetyl Tetrapeptide-3Acetyl Tetrapeptide-5 is a peptide that goes by another name, eyeseryl, due to claims that it can help reduce eye puffiness.
The manufacturer claims this ingredient reduces eye puffiness by:
An in-vivo study from the manufacturer found 95% of volunteers saw eye bag improvement by the end of the study.
Eye puffiness is caused by two major factors: fluid retention and fat.
Those with fluid retention may see improvement from using this ingredient. However, those with eye fat will need surgical intervention in order to get rid of puffiness.
Learn more about Acetyl Tetrapeptide-5Acetyl Tetrapeptide-9 is a signal peptide. Signal peptides tell your skin to create collagen or start tissue repair.
This peptide plays a role in key skin components such as collagen, lumican, and glycosaminoglycans (GAGs). Lumican is used in collagen organization and regulation, while GAGs are a component that holds water in our skin.
The manufacturer claims this ingredient is effective at firming the skin and enhancing skin hydration.
Learn more about Acetyl Tetrapeptide-9Carnosine is a dipeptide made from two amino acids.
This ingredient helps:
Glycation is the process of sugars binding to and damaging proteins. Too much sugar in our skin can lead to damaged collagen, contributing to factors of aging.
Carnosine is water-soluble and is not able to travel deeper layers of skin. This leads to some doubt about whether it can boost collagen in skin, since collagen is located in the deeper layers of skin.
Fun fact: Carnosine can be naturally found in our muscles and brain.
Learn more about CarnosineCopper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.
It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.
While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.
Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesnât turn soft, barely-visible facial hairs into thick, dark ones.
Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isnât backed by large-scale studies.
Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.
For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.
After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.
While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.
Read more about other common types of peptides here:
Learn more about Copper Tripeptide-1Nonapeptide-1 is created from amino acids including arginine and lysine.
It has antioxidant and antimicrobial properties.
Emerging studies show Nonapeptide-1 to help with reducing pigmentation and brightening the skin. It has shown to prevent the activation of tyrosinase, an enzyme in the skin that begins the process of melanin creation. Melanin is responsible for giving skin a tan or dark spots.
Learn more about Nonapeptide-1You might know this ingredient as Matrixyl. It is a synthetic peptide made up of five amino acids attached to a palmitic acid, a fatty acid that helps it absorb into skin more easily.
As a signal peptide, Matrixyl acts like a little messenger. Once it reaches your skin cells, it tells them to ramp up production of collagen, elastin, and other proteins that keep skin looking firm and smooth.
A 12 week clinical study found that a moisturizer containing just 3 ppm of Matrixyl led to a significant improvement in fine-lines and wrinkles. Another study showed an 18% reduction in wrinkle depth, 37% reduction in wrinkle thickness, and a 21% improvement in skin firmness after just 28 days of twice-daily use.
The coolest part is that it works at incredibly low concentrations (like 0.0003%) and it plays well with other actives.
The CIR (Cosmetic Ingredient Review) panel found it to be non-sensitizing across multiple tests and human patch tests also showed no irritation or sensitization.
Fun fact: Matrixyl was originally developed by French company Sederma and Procter & Gamble.
Read more about other common types of peptides here:
Learn more about Palmitoyl Pentapeptide-4Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.
That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.
Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.
In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.
Human clinical data is promising, but modest:
A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.
A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.
You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.
Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
Palmitoyl Tripeptide-5 is a synthetic signal lipopeptide. This just means it is a three amino acid chain bolted onto a palmitic acid tail so it can slip through the skin's lipid barrier.
This peptide has a "build more, lose less" approach.
It's designed to mimic the collagen-stimulating activity in your skin by copying a snippet of one of your skin's own matrix proteins. This nudges fibroblasts into making more collagen while inhibiting the enzyme that breaks down skin protein.
The manufacturer's in vivo study of 45 volunteers found 1% and 2.5% reduced the appearance of wrinkles by 7% and 12% respectively, after using it twice daily for 84 days.
This is in the expected range for peptides; they're slow and cumulative actives and not overnight fixers.
Typical use levels range from 1-3% and this ingredient gets along with pretty much everything.
On the fungal acne front:
Although palmitic acid sits in the chain length that Malassezia can feed on, this ingredient has it locked in an amine bond. This makes it hard for Malassezia to access as a source of food, and therefore fungal acne safe.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
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Read more about us· Updated June 11, 2026 • Added by parikim