Versus

Centellian24 PDRN Firming Boosting Ampoule Versus Mary & May Seoul Edition Retinol 0.1% Bakuchiol Cica Serum

Ampoule
Serum
Korean Brand South Korea
Korean Brand South Korea

Updated on December 27, 2024

Overview

What they are

These products are both cruelty-free and reef safe . They have a total of 19 ingredients in common

Cool Features

They both contain ceramides, niacinamide, peptides, retinoid and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, parabens or sulfates

What's Inside

They both contain oils and silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
PDRN Firming Boosting Ampoule

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Propanediol

Solvent

Bis-PEG-18 Methyl Ether Dimethyl Silane

Emollient

Methylpropanediol

Solvent

Dipropylene Glycol

Masking

Glycereth-26

Humectant
0 / 0

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Methyl Gluceth-20

Humectant

Raffinose

Skin Conditioning

Cyclohexasiloxane

Emollient
Silicon Icon

Pentylene Glycol

Skin Conditioning

Trehalose

Humectant

Dimethicone/Vinyl Dimethicone Crosspolymer

Skin Conditioning

Sodium Dna

Skin Conditioning

Lactobacillus Ferment

Skin Conditioning

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Curcuma Longa Root Extract

Masking
Fragrance Icon

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Tromethamine

Buffering

Glyceryl Polymethacrylate

Dioscorea Japonica Root Extract

Skin Conditioning

Ethylhexylglycerin

Skin Conditioning

Glycosyl Trehalose

Emulsion Stabilising

Sodium Polyacrylate

Absorbent

Pvm/Ma Copolymer

Emulsion Stabilising

Hydrogenated Lecithin

Emulsifying

Hydrolyzed Collagen

Emollient
Helps hydrate Dry Skin IconHelps with Anti-Aging Icon

Hydrogenated Starch Hydrolysate

Humectant

Xanthan Gum

Emulsifying

Adenosine

Skin Conditioning
Good for Minimizing Pores IconGood for Scar Healing Icon

Theobroma Cacao Seed Extract

Antioxidant
Antioxidant Icon

Dextrin

Absorbent

Hydrolyzed Elastin

Emollient

Sucrose Distearate

Emollient
0 / 2 Not safe for Fungal Acne Icon

Lecithin

Emollient

Carbomer

Emulsion Stabilising
1 / 0

Polyquaternium-51

Skin Conditioning

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

BHT

Antioxidant
Antioxidant Icon

Cyanocobalamin

Skin Conditioning

Biosaccharide Gum-1

Skin Conditioning

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Palmitoyl Pentapeptide-4

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Panax Ginseng Root Extract

Emollient
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Carnosine

Skin Conditioning

Calendula Officinalis Flower Oil

Masking
Fragrance IconOil IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Panax Ginseng Root

Emollient

Retinol

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon
Seoul Edition Retinol 0.1% Bakuchiol Cica Serum

Water

Skin Conditioning

Propanediol

Solvent

Vinyldimethicone

Silicon Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Dipropylene Glycol

Masking

Hydrogenated Lecithin

Emulsifying

Glycolipids

Skin Conditioning

Hydroxyacetophenone

Antioxidant
Antioxidant Icon

Bisabolol

Masking
Helps reduce irritation Icon

Cetyl Ethylhexanoate

Emollient

Macadamia Ternifolia Seed Oil

Emollient
Oil IconNot safe for Fungal Acne Icon

Sorbitan Stearate

Emulsifying
0 / 1 Not safe for Fungal Acne Icon

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

Polyisobutene

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

PEG-5 Rapeseed Sterol

Cleansing
Not safe for Fungal Acne Icon

Polyglyceryl-10 Laurate

Skin Conditioning
Not safe for Fungal Acne Icon

1,2-Hexanediol

Skin Conditioning

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate

Skin Conditioning

Dimethicone/Vinyl Dimethicone Crosspolymer

Skin Conditioning

Bakuchiol

Antimicrobial
Antioxidant IconHelps with Anti-Aging IconHelps brighten skin Icon

Butyrospermum Parkii Butter

Skin Conditioning
Helps hydrate Dry Skin IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Retinol

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Disodium EDTA

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Dipotassium Glycyrrhizate

Humectant
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Sucrose Cocoate

Emulsifying
Can worsen Dry Skin IconNot safe for Fungal Acne Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Antioxidant
Antioxidant Icon

Rosa Damascena Flower Water

Masking

Caprylyl/Capryl Glucoside

Cleansing

Adenosine

Skin Conditioning
Good for Minimizing Pores IconGood for Scar Healing Icon

Sorbitan Oleate

Emulsifying
3 / 0 Bad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Stearic Acid

Cleansing
2-3 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Vanilla Planifolia Fruit Extract

Skin Conditioning

Polyglutamic Acid

Skin Conditioning
Helps hydrate Dry Skin IconGood for Scar Healing Icon

Tromethamine

Buffering

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Benzotriazolyl Dodecyl P-Cresol

UV Absorber

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Polyglyceryl-10 Myristate

Skin Conditioning
Not safe for Fungal Acne Icon

Oleic Acid

Emollient
May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Santalum Album Oil

Masking
Oil IconMay cause irritation IconEU Allergen Icon

Caprylyl Glycol

Emollient

Ethylhexylglycerin

Skin Conditioning

Ceramide Ns

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Phytosphingosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Carbomer

Emulsion Stabilising
1 / 0

Arginine

Masking
Good for Scar Healing IconNot safe for Fungal Acne Icon

Ceramide As

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide AP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Centella Asiatica Leaf Extract

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon

Centella Asiatica Root Extract

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon

Centella Asiatica Extract

Cleansing
Helps reduce Skin Redness IconHelps reduce irritation Icon

Sodium Dna

Skin Conditioning

Ceramide EOP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps with Anti-Aging Icon

Palmitoyl Pentapeptide-4

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Copper Tripeptide-1

Skin Conditioning
Peptide IconGood for Skin Texture IconHelps with Anti-Aging Icon

Asiatic Acid

Skin Conditioning

Asiaticoside

Antioxidant
Antioxidant IconGood for Scar Healing Icon

Madecassic Acid

Skin Conditioning
Helps reduce irritation IconHelps with Anti-Aging Icon

Madecassoside

Antioxidant
Antioxidant IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Masking, Solvent

Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.

Dipropylene Glycol helps dissolve and evenly distribute ingredients. It also helps decrease viscosity and thin out texture.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Learn more about Dipropylene Glycol
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.
  • It has mild preservative properties.

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Smoothing

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide

This ingredient is a silicone used to improve the texture of products and absorb oil. It does not get absorbed into the skin.

Like other silicones, Dimethicone/Vinyl Dimethicone Crosspolymer helps condition the skin by creating a barrier. In this sense, it can act as an emollient and trap moisture in.

Skin Conditioning

Sodium DNA is an emerging anti-aging ingredient.

It is created by taking deoxyribonucleic acid (DNA) and purifying it with sodium hydroxide.

The DNA is extracted from several different animal sources, including: calf thymus, the gonadic tissue of a male sturgeon, or herring / salmon sperm.

You have probably seen this ingredient in anti-aging skincare. But what is it?

DNA is composed of nucleotides, or chemical building blocks. Nucleotides include adenine (A), thymine (T), guanine (G), and cytosine (C). Talk about a flashback to biology! Nucleosides are formed from these nucleotides.

The science behind Sodium DNA is based on an ingredient called Polydeoxyribonucleotide or PDRN.

PDRN are DNA fragments mainly extracted from the sperm cells of trout or salmon. Meaning, PDRN can be derived from Sodium DNA.

PDRN consists of chains of nucleotides and nucleosides mentioned above. They can range anywhere from 80 - 2000 pairs.

Studies show PDRN has the following properties:

Further studies are needed to truly confirm this ingredients anti-aging ability (Remember, retinol has decades of research!).

When using this ingredient, is is best to ask a brand about the source of their Sodium DNA. You'll want to find products where the Sodium DNA is sourced from fish. Some Sodium DNA is derived from calf / cow thymus.

Learn more about Sodium Dna

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products. Due to its properties, it can prevent water and oil ingredients from separating.

Skin Conditioning

Ceramide NP is a type of ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here: Ceramide AP Ceramide EOP

Learn more about Ceramide NP
Buffering, Masking

Tromethamine helps balance the pH and improve the texture of a product. It is synthetically created.

As an emulsifier, Tromethamine prevents oil and water ingredients from separating. This helps stabilize the product and elongate a product's shelf life. Tromethamine also makes a product thicker.

Tromethamine helps balance the pH level of a product. Normal pH level of skin is slightly acidic (~4.75-5.5). The acidity of our skin is maintained by our glands and skin biome. Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.

Oral Tromethanmine is an anti-inflammatory drug but plays the role of masking, adding fragrance, and/or balancing pH in skincare.

1,3-Propanediol, 2-amino-2-(hydroxymethyl)-

Learn more about Tromethamine
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.

This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine
Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Emollient, Emulsifying

Glyceryl Stearate is a mix of glycerin and stearic acid.

It is used to stabilize the mixing of water and oil ingredients. By preventing these ingredients from separating, it can help elongate shelf life. It can also help thicken the product's texture.

As an emollient, it helps soften skin and supports barrier-replenishing ingredients.

In cosmetics, Glyceryl Stearate is often made from vegetable oils or synthetically produced.

This ingredient may not be fungal-acne safe

Fun fact: The human body also creates Glyceryl Stearate naturally.

Learn more about Glyceryl Stearate
Antioxidant, Masking, Skin Conditioning

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol
Skin Conditioning

You might know this ingredients as Matrixyl, a famous peptide.

Peptides are building blocks for protein. Palmitoyl Pentapeptide-4 consists of five amino acids. These amino acids include: 2 lysines, 2 threonines, and serine

This ingredients tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.

Thus, Matrixyl may help improve the look of wrinkles.

Read more about other common types of peptides here:

Learn more about Palmitoyl Pentapeptide-4
Skin Conditioning

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

Why is retinol famous?

It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.

Retinol is proven to:

This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.

Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).

Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

We recommend speaking with a medical professional about using this ingredient during pregnancy.

Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.

Read about Tretinoin

Learn more about Retinol

When to use

2 Routines
0% use in am
100% use in pm
100% use every day
7 Routines
0% use in am
100% use in pm
71% use every day