MediCube Deep Reviving Bakuchiol Retinol Serum Ingredients Explained

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

It is derived from corn or petroleum with a clear color and no scent.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Due to the fatty acid content of this ingredient, it may not be Malassezia folliculitis safe.

Olive oil also contains antioxidants such as Vitamin E. Antioxidants may help reduce signs of aging by fighting unstable free-radical molecules. It also contains Vitamins A (retinol), D, and K.

The squalene in olive oil makes it a great emollient. Emollients help soothe and soften your skin by trapping moisture in. This makes olive oil a great skin moisturizer.

Studies show olive oil to have antibacterial and antifungal properties in low concentrations. Another study found olive oil irritated sensitive oily skin. We always recommend speaking with a professional about using this ingredient in your routine.

Jojoba seed oil is a humectant, meaning it helps draw moisture from the air. This helps keep your skin hydrated.

While jojoba has antibacterial properties, it is only able to kill some bacteria. It has also been shown to help in wound healing. Indigenous cultures have used jojoba as a moisturizer and to help treat burns.

It is found to be similar to natural human skin sebum, so it has a great effect on dry skin. Jojoba oil may even help with regulating sebum production.

Although jojoba oil is non-comedogenic, we recommend speaking with a professional about using this ingredient if you have any concerns.

Jojoba oil may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.

Jojoba is native to the southwestern US.

Antioxidants help fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Antioxidants help stabilize free-radicals by donating extra electrons. Grape seed extract may help reduce the signs of aging.

The antimicrobial properties of grape seed may help treat acne. However, more research is needed to support this claim.

Grape seed has also been found to help absorb UV rays. Grape seed extract should not replace your sunscreen.

The fatty acids of grape seed oil give it emollient properties. Emollients help soothe and soften your skin by creating a film. This film traps moisture within, keeping your skin hydrated.

Palmitoleic acid has been shown to help soothe inflammation and promote wound healing. It is also naturally found in the fat of our skin.

Macadamia seed oil may not be malassezia folliculitis, or fungal-acne, safe.

Studies show retinal may work at a faster rate than retinol due to its structure. Retinoids have to be converted into retinoic acid before starting to work. Some retinoids take several steps of conversion before binding. Retinal is only one step away, making it more potent.

Like other retinoids, retinal may be irritating. It is best to ease into using this ingredient daily. It is best to avoid mixing other active ingredients if you have sensitive skin.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Your body uses collagen for a variety of tasks. These tasks include repairing and maintaning tissues, helping cells communicate, and helping your body’s immune system respond to attacks.

Collagen is comprised mostly of glycine, proline, and hydroxypoline. These are amino acids.

Collagen can be used in the morning or night. It will not increase sun sensitivity, but you should always wear sunscreen during the day.

Research shows Centella Asiatica can help increase Type I collagen production by increasing fibroblast production. Fibroblast helps form connective tissue.

The combination of all these properties makes Centella Asiatica Extract effective at soothing the skin.

Other components of Centella Asiatic Extract include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.

Recent studies found madecassoside may help prevent damage from UV rays by preventing UV-induced inflammation. Further research is needed.

This plant has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Research shows centella asiatica can help increase Type I collagen production by increasing fibroblast production. Fibroblast helps form connective tissue.

The combination of all these properties makes centella asiatica leaf extract effective at soothing the skin.

Other components of centella asiatica leaf extract include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.

Recent studies found madecassoside may help prevent damage from UV rays by preventing UV-induced inflammation. Further research is needed.

This plant has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Once applied, Coco-Caprylate/Caprate is absorbed quickly and leaves a silky feel.

Coco-Caprylate/Caprate may not be fungal acne safe.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan? This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Studies show dimethyl isosorbide is able to penetrate skin to deliver other ingredients into the skin, making them more effective.

This property also makes Pentylene Glycol a great texture enhancer. It can help thicken or emulsify a product. Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating.

Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.

Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.

Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.

Another benefit is the anti-inflammatory abilities. This means that it's great for sensitive, irritation-prone skin.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

The phospholipids in Hydrogenated Lecithin can produce liposomes. Liposomes help other ingredients get through the skin barrier to be better absorbed.

As an emulsifier, it prevents oil and water ingredients from separating.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid. Caprylic Triglyceride has not been found to be toxic for human use in concentrations under 50%.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Tromethamine helps balance the pH level of a product. Normal pH level of skin is slightly acidic (~4.75-5.5). The acidity of our skin is maintained by our glands and skin biome. Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.

Oral Tromethanmine is an anti-inflammatory drug but plays the role of masking, adding fragrance, and/or balancing pH in skincare.

1,3-Propanediol, 2-amino-2-(hydroxymethyl)-

Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating. Common ingredients include oils and water, which do not mix naturally. Emulsifiers have properties that help keep ingredients such as these together.

Emollients help soothe and soften the skin. They do this by creating a protective film on your skin. This barrier helps trap moisture and keeps your skin hydrated. Emollients may be effective at treating dry or itchy skin.

Surfactants help gather oils, dirt, and other pollutants from the skin. This helps them to be easily rinsed away.

Allantoin is derived from the comfrey plant but produced synthetically for cosmetic products to ensure purity.

It is also naturally found in fruits such as apples and pears.

One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.

Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.

Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.

Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.

Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Retinol boosts collagen production and increases cell turnover. This makes retinol effective in removing wrinkles, fading dark spots, and reducing the appearance of pores.

Retinol is less effective when exposed to sun. Be sure to look for appropriate packaging to keep your retinol potent.

Using retinol and retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

We recommend speaking with a medical professional about using this ingredient during pregnancy.

Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.

Read about Tretinoin

Bakuchiol works by breaking down free radicals and stimulating collagen production in skin.

Combining bakuchiol with retinol will not have adverse side effects. Studies show using them will just boost the benefits. Bakuchiol is also found to help stabilize retinol.

While bakuchiol does not make the skin more sun sensitive, we recommend wearing SPF on a daily basis.

Read more about traditional retinol

As an antioxidant, retinyl palmitate helps neutralize free-radical molecules. These molecules have the potential to damage skin cells. Thus, antioxidants may help with anti-aging.

Retinyl palmitate can be good for be good for oily skin by helping to unclog pores. However, it may not be good for dry skin and fungal acne.

After using this product, you should follow up with sunscreen.

This ingredient is often added to low-fat milk to increase the levels of Vitamin A.

This makes linoleic acid effectives for reducing inflammation, hydrating skin, and firming skin. A side effect may include extra protection against UV damage and free radicals. This is due to linoleic acid strengthening the skin barrier.

Low levels of linoleic acid is also associated with acne-prone skin. By keeping sebum soft, it prevents pores from clogging.

Linoleic acid can is in common foods such as nuts, sunflower oil, corn oil, and soybean oil.

This ingredient may not be Malassezia folliculitis, or fungal-acne safe.

CHEM: 9,12-Octadecadienoic acid (9Z, 12Z)-

Our bodies use cholestrol to create vitamin D, steroid hormones, and more.

Polyglyceryl-10 Laurate may not be fungal acne safe.

Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here: Ceramide AP Ceramide EOP

Beta-Glucan has antioxidant properties. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

Studies show Beta-Glucan may be an effective wrinkle reducer as it can deeply penetrate into skin. It has also been show to help with wound healing.

As an antioxidant, it helps fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Thus, antioxidants may reduce the signs of aging.

This ingredient is oil-soluble.

As a cleansing agent, Potassium Cetyl Phosphate helps gather oils, dirts, and pollutants from your skin. This makes it easier to rinse them away with water.

One of the manufacturer for this ingredient states it is vegetable-based. It is also claimed to be stable at both high and low temperatures.

This ingredient may not be safe for fungal acne. We recommend speaking with a professional if you have any concerns.

Silica is present naturally within the skin during collagen production and when reducing inflammation.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance. One example is Calendula flower extract. Essential oil ingredients still impart a scent or 'fragrance'.

Depending on the blend, it can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Products use parfum often to give products a scent or cover up smells of different ingredients.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.