Noble Panacea The Absolute Rejuvenation Night Balm Ingredients Explained

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid. Caprylic Triglyceride has not been found to be toxic for human use in concentrations under 50%.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Manufacturers use the name Olivem 1000. This ingredient has been found to preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria. This ingredient is grouped with Sorbitan Olivate under the name Olivem 1000.

Manufacturers sell sorbitan olivate under the name OliveM 1000. OliveM 1000 a multifunctional ingredient. It is self-emulsifying. According to a manufacturer, OliveM 1000 does not disrupt natural skin biome.

Antioxidants help fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Antioxidants help stabilize free-radicals by donating extra electrons. This may help reduce the signs of aging.

The fragrance of Rosa Damascena Flower Water may be used for masking. Masking ingredients are used to obscure or block properties of other ingredients. They are commonly used to block the scent of a product.

Aloe Barbadensis Leaf Juice also contains sugars. These sugars come in the form of monosaccharides and polysaccharides, folic acid, and choline. These sugars are able to help bind moisture to skin.

It also contains minerals such as calcium, 12 anthraquinones, fatty acids, amino acids, and Vitamin B12.

It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.

Retinol is proven to:

This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.

Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).

Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

We recommend speaking with a medical professional about using this ingredient during pregnancy.

Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.

Read about Tretinoin

One study suggests phlorotannins may even have some sun protection factor due to their antioxidant activity. However, this ingredient should not replace your sunscreen.

Macrocystis pyrifera is made up of about: 60% carbohydrates, 10% protein, and 1.50% lipid content. The last 30% is kelp ash.

This kelp can be found in the southern hemisphere and north Pacific.

Not only does it help exfoliate the skin, it helps strengthen the skin's barrier. When applied, lactic acid helps the skin create ceramides.

Lactic acid is an over-the-counter chemical exfoliant that comes from the fermentation of lactose — a carbohydrate found in milk.

Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.

Read more about some other popular AHA's here:

Specifically, AHAs work by breaking down the structural "glue" holding the old skin cells in place. Getting rid of the old skin cells allows skin to regenerate newer skin cells in its place. A build up of dead skin cells can lead to tired and dull looking skin.

Due to this, glycolic acid helps with:

Fun fact: Glycolic acid increases skin hydration by playing a role in creating molecules that create hyaluronic acid naturally.

When starting glycolic Acid, it is normal to feel slight stinging.

The pH value and concentration of glycolic acid play a role in the effectiveness of the product. Concentrations between 5-20% glycolic acid have been shown to be effective in clinical studies.

Recent studies have shown Glycolic Acid may protect the skin against UV damage. However, you should always wear SPF, especially when using exfoliants.

Read more about some other popular AHA's here:

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Vitamin C is best used for brightening skin. It improves dark spots, acne scars, and hyperpigmentation. This is because it blocks the process of skin darkening when exposed to UV.

Remember: Vitamin C should not replace sunscreen!

Your skin uses vitamin C to build collagen. Collagen is one key component in having a strong skin barrier and plump skin. Vitamin C also plays a role in regulating collagen, thus making it effective in improving wrinkles and fine lines.

Ascorbic acid shows potent antioxidant activity. As an antioxidant, it helps fight free-radicals. Free-radicals are molecules that may damage your skin cells. These antioxidants also protect skin against UV damage.

The best formulations include Vitamin E and/or ferulic acid. These two ingredients help stabilize and provide a boost in the benefits of ascorbic acid. This is because ascorbic acid becomes unstable when exposed to UV and air. In fact, you can tell your ascorbic acid has oxidized when it turns an orange-yellow color.

Ascorbic acid is generally compatible with other ingredients. However, using ascorbic acid with other active ingredients might cause irritation. Two ingredients: copper ions and benzoyl peroxide, will inactivate ascorbic acid completely.

Read more about other types of Vitamin C:

Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.

Ascorbyl Glucoside is an antioxidant. Antioxidants help fight free-radicals, or molecules that may damage skin cells.

It can help to reduce redness, improve skin texture, reduce the effects of aging, reduce the visibility of dark spots, and brighten skin.

Read more about other types of Vitamin C:

Ascorbyl Palmitate is a stable version of Vitamin C, meaning it does not disintegrate when exposed to sunlight. However, studies show it does not penetrate skin as well as pure Vitamin C.

Read more about other types of Vitamin C:

Due to MAP's stability up to a pH level of 7, it is more stable to air and sunlight exposure than ascorbic acid. The best pH range for MAP is between 5 and 6.

Like other forms of Vitamin C, MAP has been shown to help reduce hyperpigmentation and simulate collagen production.

As an antioxidant, it helps protect your skin against the signs of aging.

Allantoin is derived from the comfrey plant but produced synthetically for cosmetic products to ensure purity.

Studies find EGF help with:

In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.

According to Dr. Zoe Draelos, growth factors have some drawbacks:

There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause changes in your DNA to cause cancer.

Argireline tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.

Read more about other common types of peptides here:

The antioxidants in chondrus crispus help fight free-radical molecules. These molecules may damage skin cells and DNA. Antioxidants present in chondrus crispus include lutein and zeaxanthin.

Lutein has the ability to filter blue light from screens.

Other contents of chondrus crispus include polysaccharides, peptides, and amino acids. These help hydrate the skin.

This ingredient contains polyphenols, a strong antioxidant. Antioxidants help fight off molecules that damage skin cells.

On top of that, the antioxidants in green tea neutralize free-radicals from the sun. This gives the skin some extra UV protection, but should not replace sunscreen.

Many components of tea have anti-inflammatory properties.

Polyphenols and L-theanine help soothe the skin and reduce irritation. The caffeine in Camellia Sinensis Leaf Extract helps calm inflamed blood vessels.

Other compounds found in tea include: Vitamin Bs, linoleic acid, magnesium, calcium, iron, and zinc.

Research has shown both drinking Camellia Sinensis Leaf Tea and applying it to the skin can help boost skin elasticity and hydration. Studies also show using tea extract may reduce sebum, or oil, production.

Its soothing ability comes from a variety of compounds including biflavones, a type of flavonoid. Studies show gingko biloba has strong anti-inflammatory properties.

Laminaria Digitata contains amino acids, proteins, sugars, and vitamins. Small amounts of minerals such as phosphorous, iron, potassium, and copper are also found the seaweed. These components help hydrate and nourish your skin's natural barrier. Having a healthy skin barrier leads to more youthful looking skin and may help reduce the signs of aging.

Laminaria Digitata is found in the northern Atlantic Ocean.

And of course, lemons are rich in Vitamin C. Vitamin C helps with skin-brightening and increasing collagen production.

The acidity of lemons may work as an astringent for acne.

However, lemons can also cause skin sensitivity due to its limonene content. It can also increase photosensitivity, or sensitivity to the sun.

This ingredient is also used to add a lemon scent to products.

It can also be mildly exfoliating due to the citric acid, an AHA.

Citrus fruits are rich in flavonoids, alkaloids, and vitamin C.

The good news is: studies show applying this ingredient topically replenishes ubiquinone levels in our skin. This also comes with a ton of skin benefits. These benefits include:

Ubiquinone is considered a large molecule and cannot be absorbed into the lower layers of skin. This is why it is believed to be such an effective antioxidant: it protects our skin in the upper layers and prevents damage in the deeper layers.

When used in sunscreen, ubiquinone is shown to increase ingredient stability, increase SPF factor, and add to infrared protection.

Fun fact: ubiquinone is fat-soluble.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

CASE contains several ingredients that protect and soothe skin. These include caffeine, polysaccharides, sucrose, lipids, minerals, and proteins.

The star ingredient in coffee is caffeine.

Caffeine helps with anti-aging, antioxidant, and photo-protection.

How? It has been shown to block collagenase (~41%), elastase (~35%), and tyrosinase (~13%).

Collagenase and elastase are enzymes that break down collagen and elastin, respectively. Tyrosinase is the enzyme that controls melanin production.

Our skin creates melanin when exposed to UV as a defense mechanism.

It should be noted most studies looked at caffeine's ability to inhibit damage from UV-B rays.

According to a manufacturer, this ingredient is often dissolved using water, glycerin, and propanediol. The caffeine content of this ingredient is about 100 ppm.

Coffea Arabica is native to Ethiopia.

Avocado Oil is mostly made up of the glycerides of fatty acids. About 67% of these fatty acids is made up of oleic acid. Palmitic acid and linoleic acid are also present.

These fatty acids help hydrate and soften the skin. It may increase collagen content in the skin. Collagen helps keep your skin plump and firm.

Avocado Oil reduces inflammation and has not shown to clog glands.

Avocados also have B vitamins, vitamin K, vitamin C, vitamin E, and potassium.

Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here: Ceramide AP Ceramide EOP

The cellulose and fiber in colloidal oatmeal help reduce inflammation. This can also help the skin feel softer.

Colloidal Oatmeal is also an antioxidant. Antioxidants protect our skin from free-radical damage.

Oatmeal also contains beneficial compounds:

This ingredient is created by mixing grounded oatmeal and a liquid base.

Oryza Sativa Bran Extract contains numerous antioxidants such as ferulic acid. Antioxidants help fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material.

In vivo studies show folic acid to increase UV-C induced DNA damage on human fibroblasts. This is because folic acid is effective at rejoining breaks in the fibroblast DNA. It is believed folic acid may play a role in reducing UV-B damage as well. While the mechanisms are unknown, it is believed folic acid plays a role in disrupting the DNA damage process.

Studies show using moisturizers rich in folic acid led to increased hydration of the skin. Hydrated skin is essential for collagen and elastin, or for keeping skin plump. One study found a reduction in wrinkles from using folic acid creams.

Foods rich in folic acid include leafy vegetables, beans, peanuts, fresh fruit, and eggs.

Antioxidants help fight off free-radicals, molecules that may damage skin cells.

When paired with niacinamide, Acetyl Glucosamine has been shown to be effective at reducing discoloration.

Read more about other types of Vitamin C:

Palmitoleic acid has been shown to help soothe inflammation and promote wound healing. It is also naturally found in the fat of our skin.

Macadamia seed oil may not be malassezia folliculitis, or fungal-acne, safe.

It is also naturally found in fruits such as apples and pears.

Another great component of Rosehip Oil is Vitamin A, or retinol. Vitamin A encourages your skin to create more collagen.

Rosehip oil may help with reducing pigmentation. The lycopene and beta-carotene have skin-lightening properties.

The content of sweet almond oil makes it a great emollient; it can help soften and hydrate your skin. Emollients create a barrier over your skin to trap moisture in. Sweet almond oil has antioxidant properties. This may help with anti-aging, as antioxidants help fight free-radicals. Free-radicals are unstable molecules that may damage your skin's cells.

Those with an almond allergy should be careful of this ingredient and speak with a professional about using it in your skincare.

This ingredient may not be fungal-acne safe.

Studies show phospholipids display antioxidant activity and may help with reducing the signs of aging.

Phospholipids are complex lipids that contain glycerin, two fatty acids, and a phosphate group. Some foods that contain phospholipids include soybeans and milk. The phospholipids found in soy come from Lecithin. This ingredient can also be synthetically created.

Some types of phospholipids:

Rosemary Leaf Extract can help protect your skin against damage from free-radical molecules. It contains many antioxidants such as rosmarinic acid and caffeic acid. Rosemarinic acid has been found to help soothe skin conditions such as eczema and acne.

Glycolic acid is a derivative of sugarcane. While glycolic acid is an AHA with exfoliating properties, sugarcane is not an AHA.

A study from 2021 found the compounds in sugarcane extract to have antioxidant, antimicrobial, and anti-inflammatory activity. The study also suggests these compounds can inhibit skin ageing enzymes and promote collagen synthesis.

As an astringent, Punica Granatum Extract shrinks tissue by drawing water out of your skin. This leads to a tightening effect in the skin.

Shea butter is rich in antioxidants. Antioxidants help fight free-radicals, or molecules that may harm the body. It is also full of fatty acids including stearic acid and linoleic acid. These acids help replenish the skin and keep skin moisturized.

While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.

Shea butter may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.

Vaccinium Myrtillus Fruit Extract also helps reduce irritation.

As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can help ingredients be better absorbed by the skin. The phospholipids in Lecithin can produce liposomes. Liposomes help other ingredients get through the skin barrier.

The fatty acids found in sunflowers include (from highest amount to least): linoleic acid, myristic acid, palmitic acid, stearic acid, arachidic acid, oleic acid, and linolenic acid.

These fatty acids hydrate your skin. Emollients create a film on the skin to prevent moisture from escaping.

Aleurites Moluccanus Seed Oil can also help soothe the skin.

This nut has been used by many cultures for curing illnesses, such as headache and fever.

Antioxidants help fight free-radical molecules that may damage your skin's DNA. This may help with the signs of aging. Due to its antioxidant property, it is used to help treat chronic inflammation.

In cosmetics, SOD is usually obtained from marine phytoplankton, bovine liver, horseradish, cantaloupe, and certain bacteria.

The three major families of SOD include: Copper/Zinc, Iron/Manganese, and Nickel.

When eating SOD-rich foods, our bodies break it down into amino acids before absorption. Foods that contain SOD include: melons, citrus, spinach, broccoli, kale, almonds, sunflower seeds, and blue-green algae.

Using high concentrations of Potassium Hydroxide have shown to irritate the skin.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

PHAs are more gentle than AHAs due to their larger structure. They do not penetrate as deeply as AHAs and take a longer time to dissolve dead cells. Studies show PHAs do not cause as much irritation.

Gluconolactone has some interesting properties:

In a 2004 study, Gluconolactone was found to prevent UV damage in mouse skin cells. Gluconolactone has not been found to increase sun sensivity. However, we still recommend wearing SPF daily.

This ingredient is is an created by reacting gluconic acid with an alcohol.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

Sodium Benzoate is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.