Missha Time Revolution Night Repair Probio Ampoule Versus Missha Time Revolution Prismestem100 Lifting Serum
This barrier-repair ampoule is formulated around Bifida Ferment Lysate and Niacinamide to strengthen the skin barrier and soften the look of wrinkles.
This anti-aging serum is formulated around Niacinamide and Adenosine to soften the look of wrinkles.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningBifida Ferment Lysate
Skin ConditioningGlycereth-26
HumectantSorbus Commixta Extract
Skin ConditioningJuniperus Chinensis Xylem Extract
Skin ConditioningBis-PEG-18 Methyl Ether Dimethyl Silane
EmollientButylene Glycol
HumectantGlycerin
HumectantNiacinamide
SmoothingLeuconostoc Ferment Filtrate
AntimicrobialBetaine
HumectantGrifola Frondosa/Ophioglossum Vulgatum Extract Ferment Filtrate
Skin ConditioningLactobacillus/Rice Ferment Filtrate
Skin ConditioningPortulaca Oleracea Extract
Skin ConditioningSodium Hyaluronate
HumectantAnthemis Nobilis Flower Extract
MaskingHydrolyzed Rice Extract
Skin ConditioningSea Water
HumectantCarthamus Tinctorius Oleosomes
EmollientHydrolyzed Extensin
Skin ConditioningAdenosine
Skin ConditioningDaucus Carota Sativa Root Extract
Skin ConditioningVaccinium Angustifolium Fruit Extract
Skin ProtectingBeta Vulgaris Root Extract
Skin ConditioningAronia Arbutifolia Extract
Skin ConditioningBrassica Oleracea Capitata Leaf Extract
Skin ConditioningEchium Plantagineum Seed Oil
Skin ConditioningAscorbyl Tetraisopalmitate
AntioxidantLactobacillus Ferment
Skin ConditioningLactococcus Ferment Lysate
Skin ConditioningManilkara Multinervis Leaf Extract
Skin ConditioningTheobroma Cacao Seed Extract
AntioxidantCassia Alata Leaf Extract
AstringentLaminaria Digitata Extract
Skin ProtectingSaccharomyces Ferment Filtrate
HumectantLactobacillus/Soybean Ferment Extract
Skin ConditioningSaccharomyces/Viscum Album Ferment Extract
Skin ConditioningYeast Ferment Extract
Skin ConditioningPogostemon Cablin Leaf Oil
MaskingPseudoalteromonas Ferment Extract
HumectantCardiospermum Halicacabum Flower/Leaf/Vine Extract
Skin ConditioningHelianthus Annuus Seed Oil Unsaponifiables
EmollientAlpha-Glucan Oligosaccharide
CleansingLimnanthes Alba Seed Oil
Skin ConditioningHydrolyzed Wheat Protein
Skin ConditioningBeta-Sitosterol
Emulsion StabilisingPanthenol
Skin ConditioningHydrolyzed Soy Protein
HumectantUbiquinone
AntioxidantMacadamia Ternifolia Seed Oil
EmollientRetinol
Skin ConditioningCucumis Melo Fruit Extract
Skin ConditioningBiotin
AntiseborrhoeicBrassica Campestris Sterols
EmollientSodium Ascorbyl Phosphate
AntioxidantAmaranthus Caudatus Seed Extract
Skin ConditioningTripeptide-10 Citrulline
Skin ConditioningAcetyl Hexapeptide-8
HumectantCopper Tripeptide-1
Skin ConditioningTripeptide-1
Skin ConditioningAcacia Arabica Stem Bark Extract
Skin ConditioningCholesterol
EmollientGlyceryl Linolenate
EmollientGlyceryl Linoleate
EmollientGlyceryl Arachidonate
EmollientCyclopentasiloxane
EmollientEthyl Hexanediol
SolventDimethicone
EmollientPEG-11 Methyl Ether Dimethicone
EmulsifyingPEG-40 Hydrogenated Castor Oil
EmulsifyingPPG-26-Buteth-26
Skin ConditioningPolysorbate 20
EmulsifyingCarbomer
Emulsion StabilisingGlyceryl Caprylate
EmollientTriethanolamine
BufferingDimethicone/Vinyl Dimethicone Crosspolymer
Skin ConditioningOctyldodecanol
EmollientXanthan Gum
EmulsifyingDipropylene Glycol
HumectantCyclomethicone
EmollientHydrogenated Lecithin
EmulsifyingDisodium EDTA
Dextrin
AbsorbentLauryl Methacrylate/Glycol Dimethacrylate Crosspolymer
Glyceryl Polyacrylate
Dimethiconol
EmollientPropylene Glycol
HumectantCeteth-24
CleansingCholeth-24
EmulsifyingHydroxypropyltrimonium Maltodextrin Crosspolymer
SurfactantCetyl Phosphate
EmulsifyingCaprylic/Capric Triglyceride
MaskingLecithin
EmollientPEG-5 Rapeseed Sterol
CleansingBHT
AntioxidantCeteth-3
EmulsifyingCeteth-5
EmulsifyingSilica
AbrasiveTocopheryl Acetate
AntioxidantPhenoxyethanol
PreservativeWater, Bifida Ferment Lysate, Glycereth-26, Sorbus Commixta Extract, Juniperus Chinensis Xylem Extract, Bis-PEG-18 Methyl Ether Dimethyl Silane, Butylene Glycol, Glycerin, Niacinamide, Leuconostoc Ferment Filtrate, Betaine, Grifola Frondosa/Ophioglossum Vulgatum Extract Ferment Filtrate, Lactobacillus/Rice Ferment Filtrate, Portulaca Oleracea Extract, Sodium Hyaluronate, Anthemis Nobilis Flower Extract, Hydrolyzed Rice Extract, Sea Water, Carthamus Tinctorius Oleosomes, Hydrolyzed Extensin, Adenosine, Daucus Carota Sativa Root Extract, Vaccinium Angustifolium Fruit Extract, Beta Vulgaris Root Extract, Aronia Arbutifolia Extract, Brassica Oleracea Capitata Leaf Extract, Echium Plantagineum Seed Oil, Ascorbyl Tetraisopalmitate, Lactobacillus Ferment, Lactococcus Ferment Lysate, Manilkara Multinervis Leaf Extract, Theobroma Cacao Seed Extract, Cassia Alata Leaf Extract, Laminaria Digitata Extract, Saccharomyces Ferment Filtrate, Lactobacillus/Soybean Ferment Extract, Saccharomyces/Viscum Album Ferment Extract, Yeast Ferment Extract, Pogostemon Cablin Leaf Oil, Pseudoalteromonas Ferment Extract, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Helianthus Annuus Seed Oil Unsaponifiables, Alpha-Glucan Oligosaccharide, Limnanthes Alba Seed Oil, Hydrolyzed Wheat Protein, Beta-Sitosterol, Panthenol, Hydrolyzed Soy Protein, Ubiquinone, Macadamia Ternifolia Seed Oil, Retinol, Cucumis Melo Fruit Extract, Biotin, Brassica Campestris Sterols, Sodium Ascorbyl Phosphate, Amaranthus Caudatus Seed Extract, Tripeptide-10 Citrulline, Acetyl Hexapeptide-8, Copper Tripeptide-1, Tripeptide-1, Acacia Arabica Stem Bark Extract, Cholesterol, Glyceryl Linolenate, Glyceryl Linoleate, Glyceryl Arachidonate, Cyclopentasiloxane, Ethyl Hexanediol, Dimethicone, PEG-11 Methyl Ether Dimethicone, PEG-40 Hydrogenated Castor Oil, PPG-26-Buteth-26, Polysorbate 20, Carbomer, Glyceryl Caprylate, Triethanolamine, Dimethicone/Vinyl Dimethicone Crosspolymer, Octyldodecanol, Xanthan Gum, Dipropylene Glycol, Cyclomethicone, Hydrogenated Lecithin, Disodium EDTA, Dextrin, Lauryl Methacrylate/Glycol Dimethacrylate Crosspolymer, Glyceryl Polyacrylate, Dimethiconol, Propylene Glycol, Ceteth-24, Choleth-24, Hydroxypropyltrimonium Maltodextrin Crosspolymer, Cetyl Phosphate, Caprylic/Capric Triglyceride, Lecithin, PEG-5 Rapeseed Sterol, BHT, Ceteth-3, Ceteth-5, Silica, Tocopheryl Acetate, Phenoxyethanol
Water
Skin ConditioningMethylpropanediol
SolventGlycerin
HumectantBetaine
HumectantGlycereth-26
HumectantMethyl Gluceth-20
HumectantNiacinamide
SmoothingPentylene Glycol
Skin ConditioningHelichrysum Italicum Flower Water
Skin ConditioningChondrus Crispus Extract
Skin ConditioningXylitylglucoside
HumectantPolyglyceryl-10 Laurate
Skin ConditioningSaccharum Officinarum Extract
MoisturisingAnhydroxylitol
HumectantAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingAngelica Archangelica Callus Extract
Skin ProtectingTromethamine
Buffering1,2-Hexanediol
Skin ConditioningXylitol
HumectantButylene Glycol
HumectantXanthan Gum
EmulsifyingEthylhexylglycerin
Skin ConditioningOctanediol
Adenosine
Skin ConditioningParfum
MaskingBiosaccharide Gum-1
HumectantHydrolyzed Hyaluronic Acid
HumectantSodium Phytate
Coccinia Indica Fruit Extract
Skin ConditioningEclipta Prostrata Extract
Skin ConditioningDextrin
AbsorbentTheobroma Cacao Seed Extract
AntioxidantBeta-Glucan
Skin ConditioningTocopherol
AntioxidantHydroxystearic Acid
CleansingLimnanthes Alba Seed Oil
Skin ConditioningMaltodextrin
AbsorbentDipropylene Glycol
HumectantHydrogenated Lecithin
EmulsifyingPolyglyceryl-10 Oleate
Skin ConditioningPolyglyceryl-3 Methylglucose Distearate
EmulsifyingSwertia Chirata Extract
HumectantCholeth-24
EmulsifyingCeramide NP
Skin ConditioningWater, Methylpropanediol, Glycerin, Betaine, Glycereth-26, Methyl Gluceth-20, Niacinamide, Pentylene Glycol, Helichrysum Italicum Flower Water, Chondrus Crispus Extract, Xylitylglucoside, Polyglyceryl-10 Laurate, Saccharum Officinarum Extract, Anhydroxylitol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Angelica Archangelica Callus Extract, Tromethamine, 1,2-Hexanediol, Xylitol, Butylene Glycol, Xanthan Gum, Ethylhexylglycerin, Octanediol, Adenosine, Parfum, Biosaccharide Gum-1, Hydrolyzed Hyaluronic Acid, Sodium Phytate, Coccinia Indica Fruit Extract, Eclipta Prostrata Extract, Dextrin, Theobroma Cacao Seed Extract, Beta-Glucan, Tocopherol, Hydroxystearic Acid, Limnanthes Alba Seed Oil, Maltodextrin, Dipropylene Glycol, Hydrogenated Lecithin, Polyglyceryl-10 Oleate, Polyglyceryl-3 Methylglucose Distearate, Swertia Chirata Extract, Choleth-24, Ceramide NP
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineBetaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.
Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.
Some studies suggest betaine may support making skin tone more even.
Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.
Betaine is also known as trimethylglycine.
Learn more about BetaineButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCholeth-24 comes from the cholesterol of lanolins. It is used as an emulsifier, or to help stabilize other ingredients.
This ingredient is soluble in both water and alcohol.
Dextrin is a starch-derived polysaccharide. It's made by partially breaking down corn, potato, or other plant starches.
Think of it as "half-processed" starch; it's less complex than the original but not fully broken down into sugar like maltodextrin.
In cosmetics, it mainly functions as a bulking agent, viscosity controller, binder, and absorbent. It helps thicken products, stabilize powders, and get certain textures a less "wet" feel.
This ingredient has a pretty solid safety profile; it's recognized as a safe food additive and its large molecular size means it doesn't meaningfully penetrate skin.
Human repeat insult patch tests using a rinse-off facial product containing 42.69% dextrin found no skin irritation or sensitization in 54 subjects.
Typical real-world usage is much lower: usually under 1% as a texture modifier and up to 40% in masks (rinse off products use less).
Learn more about DextrinDipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.
This ingredient helps:
Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.
As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.
Studies show Dipropylene Glycol is considered safe to use in skincare.
Learn more about Dipropylene GlycolGlycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.
It is a humectant and helps add texture to products. It can make your product thicker.
As a humectant, it helps draw moisture from the air to your skin. This helps your skin stay hydrated.
Learn more about Glycereth-26Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinHydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Learn more about Hydrogenated LecithinLimnanthes Alba Seed Oil is from the seeds of the meadowfoam plant. It is a skin conditioning agent and emollient that sits on top of skin to soften and hydrate it.
Over 98% of the oil is made up of long-chain fatty acids, mostly aachidic acid (61%), docosenoic acid (~16%), and docosadienoic acid (~18%).
This combination is not really found in any other plant oil and is the reason this is one of the most stable botanical oils available.
Some studies show it to be more stable than jojoba oil, helps a product resist going rancid, and can help extend the shelf life of a formula.
It also naturally contains vitamin E and phytosterols that give it a mild antioxidant benefit.
This ingredient is typically used from around 1% to fairly high levels since it's gentle; it's well-tolerated and low on the irritation scale.
Learn more about Limnanthes Alba Seed OilNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideTheobroma Cacao Seed Extract comes from the Theobroma cacoa, or Cacao tree. Cacao trees are native to tropical landscapes.
Cacao seed extract contains antioxidants known as polyphenols.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum