Dr. Dennis Gross Skincare DermInfusionsā¢ Fill + Repair Serum Versus Paula's Choice Peptide Booster
Updated on July 18, 2024
Overview
What they are
These products are both cruelty-free and reef safe . They have a total of 12 ingredients in common
Cool Features
They both contain AHA and peptides
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, common allergens, oils, parabens or sulfates
What's Inside
They both contain silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Dr. Dennis Gross Skincare DermInfusionsā¢ Fill + Repair Serum 78 ingredients
Paula's Choice Peptide Booster 56 ingredients
What's inside
What's inside
At a glance
Click on any of the items below to learn more
Dr. Dennis Gross Skincare DermInfusionsā¢ Fill + Repair Serum 78 ingredients
Paula's Choice Peptide Booster 56 ingredients
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
Humectant
Niacinamide
Smoothing
Butylene Glycol
Humectant
Ectoin
Skin Conditioning
Sodium Hyaluronate
Humectant
Hydrolyzed Sodium Hyaluronate
Skin Conditioning
Sodium Acetylated Hyaluronate
Humectant
Sodium Hyaluronate Crosspolymer
Humectant
Acetyl Hexapeptide-8
Humectant
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Oligopeptide-2
Skin Conditioning
Saccharide Isomerate
Humectant
Camellia Sinensis Leaf Extract
Antimicrobial
Centella Asiatica Extract
Cleansing
Vitis Vinifera Seed Extract
Antimicrobial
Sodium Carboxymethyl Beta-Glucan
CleansingBakuchiol
Antimicrobial
Inonotus Obliquus Extract
Skin ConditioningTetrahydrocurcumin
Antioxidant
Ceramide NP
Skin Conditioning
Ceramide AP
Skin Conditioning
Ceramide EOP
Skin Conditioning
Phospholipids
Skin Conditioning
Sphingolipids
EmollientPhytosphingosine
Skin Conditioning
Colloidal Oatmeal
Absorbent
Bisabolol
Masking
Superoxide Dismutase
Antioxidant
Terminalia Ferdinandiana Fruit Extract
Antioxidant
Sodium PCA
Humectant
Glutathione
Squalane
Emollient
Caffeine
Skin Conditioning
Panthenol
Skin Conditioning
Butyrospermum Parkii Butter
Skin Conditioning
Aloe Barbadensis Leaf Juice
Skin Conditioning
Arnica Montana Flower Extract
Masking
Acetyl Glutamine
Skin ConditioningBifida Ferment Lysate
Skin Conditioning
Chamomilla Recutita Flower Extract
Masking
Withania Somnifera Root Extract
Skin Conditioning
Glycolic Acid
Buffering
Mandelic Acid
Antimicrobial
Lactobionic Acid
Buffering
Ethylhexylglycerin
Skin ConditioningCoco-Glucoside
CleansingLauryl Glucoside
CleansingDecyl Glucoside
CleansingPolyglyceryl-10 Laurate
Skin Conditioning
Diheptyl Succinate
EmollientDimethicone
Emollient
Pentylene Glycol
Skin ConditioningSodium Lauroyl Lactylate
EmulsifyingPvm/Ma Decadiene Crosspolymer
Vp/Va Copolymer
Xanthan Gum
EmulsifyingPotassium Hydroxide
BufferingPolysorbate 20
Emulsifying
Dimethicone Crosspolymer
Emulsion Stabilising
Carbomer
Emulsion StabilisingCholesterol
Emollient
Capryloyl Glycerin/Sebacic Acid Copolymer
Skin ConditioningLeuconostoc/Radish Root Ferment Filtrate
Antimicrobial
Sodium Citrate
BufferingCitric Acid
Buffering
Sodium Metasilicate
BufferingGluconolactone
Skin Conditioning
Tetrasodium Glutamate Diacetate
Caprylic/Capric Triglyceride
Masking
Jasminum Officinale Flower/Leaf Extract
Masking
Vitis Vinifera Fruit Extract
Skin ConditioningEugenia Caryophyllus Flower Extract
AstringentLavandula Angustifolia Flower/Leaf/Stem Extract
Masking
Raspberry Ketone
Masking
Phenoxyethanol
Preservative
Potassium Sorbate
Preservative
Water, Glycerin, Niacinamide, Butylene Glycol, Ectoin, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Sodium Hyaluronate Crosspolymer, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Oligopeptide-2, Saccharide Isomerate, Camellia Sinensis Leaf Extract, Centella Asiatica Extract, Vitis Vinifera Seed Extract, Sodium Carboxymethyl Beta-Glucan, Bakuchiol, Inonotus Obliquus Extract, Tetrahydrocurcumin, Ceramide NP, Ceramide AP, Ceramide EOP, Phospholipids, Sphingolipids, Phytosphingosine, Colloidal Oatmeal, Bisabolol, Superoxide Dismutase, Terminalia Ferdinandiana Fruit Extract, Sodium PCA, Glutathione, Squalane, Caffeine, Panthenol, Butyrospermum Parkii Butter, Aloe Barbadensis Leaf Juice, Arnica Montana Flower Extract, Acetyl Glutamine, Bifida Ferment Lysate, Chamomilla Recutita Flower Extract, Withania Somnifera Root Extract, Glycolic Acid, Mandelic Acid, Lactobionic Acid, Ethylhexylglycerin, Coco-Glucoside, Lauryl Glucoside, Decyl Glucoside, Polyglyceryl-10 Laurate, Diheptyl Succinate, Dimethicone, Pentylene Glycol, Sodium Lauroyl Lactylate, Pvm/Ma Decadiene Crosspolymer, Vp/Va Copolymer, Xanthan Gum, Potassium Hydroxide, Polysorbate 20, Dimethicone Crosspolymer, Carbomer, Cholesterol, Capryloyl Glycerin/Sebacic Acid Copolymer, Leuconostoc/Radish Root Ferment Filtrate, Sodium Citrate, Citric Acid, Sodium Metasilicate, Gluconolactone, Tetrasodium Glutamate Diacetate, Caprylic/Capric Triglyceride, Jasminum Officinale Flower/Leaf Extract, Vitis Vinifera Fruit Extract, Eugenia Caryophyllus Flower Extract, Lavandula Angustifolia Flower/Leaf/Stem Extract, Raspberry Ketone, Phenoxyethanol, Potassium Sorbate
Water
Skin ConditioningGlycerin
Humectant
PEG-8 Dimethicone
Emulsifying
Tripeptide-1
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Palmitoyl Hexapeptide-12
Skin Conditioning
Myristoyl Hexapeptide-16
Skin Conditioning
Myristoyl Pentapeptide-17
Skin Conditioning
Hexanoyl Dipeptide-3 Norleucine Acetate
Skin Conditioning
Azelaoyl Bis-Dipeptide-10
Skin Conditioning
Glycoproteins
Skin Conditioning
Phospholipids
Skin Conditioning
Adenosine
Skin Conditioning
Dipotassium Glycyrrhizate
Humectant
Arginine
Masking
Valine
MaskingGlycine
Buffering
Alanine
MaskingGlutamic Acid
Humectant
Serine
Masking
Threonine
Yeast Extract
Skin Conditioning
Isoleucine
Skin ConditioningProline
Skin ConditioningHistidine
Humectant
Phenylalanine
Masking
PCA
Humectant
Phytic Acid
Panax Ginseng Root Extract
Emollient
Sodium PCA
Humectant
Psidium Guajava Fruit Extract
AstringentEuterpe Oleracea Fruit Extract
Ahnfeltiopsis Concinna Extract
Skin Conditioning
Dextran
Hydrolyzed Silk
Humectant
Lecithin
Emollient
Glyceryl Polymethacrylate
C12-16 Pareth-9
EmulsifyingTrideceth-12
EmulsifyingSodium Lactate
BufferingCarbomer
Emulsion StabilisingAspartic Acid
Masking
Polysorbate 20
Emulsifying
Butylene Glycol
Humectant
Caprylyl Glycol
Emollient
PEG-8
HumectantC11-15 Pareth-7
EmulsifyingGuar Hydroxypropyltrimonium Chloride
Skin ConditioningPhytosteryl/Octyldodecyl Lauroyl Glutamate
Skin ConditioningEctoin
Skin Conditioning
Citrate Buffer
Trimethylsiloxyamodimethicone
Phenoxyethanol
Preservative
Sodium Hydroxide
BufferingEthylhexylglycerin
Skin ConditioningWater, Glycerin, PEG-8 Dimethicone, Tripeptide-1, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Myristoyl Hexapeptide-16, Myristoyl Pentapeptide-17, Hexanoyl Dipeptide-3 Norleucine Acetate, Azelaoyl Bis-Dipeptide-10, Glycoproteins, Phospholipids, Adenosine, Dipotassium Glycyrrhizate, Arginine, Valine, Glycine, Alanine, Glutamic Acid, Serine, Threonine, Yeast Extract, Isoleucine, Proline, Histidine, Phenylalanine, PCA, Phytic Acid, Panax Ginseng Root Extract, Sodium PCA, Psidium Guajava Fruit Extract, Euterpe Oleracea Fruit Extract, Ahnfeltiopsis Concinna Extract, Dextran, Hydrolyzed Silk, Lecithin, Glyceryl Polymethacrylate, C12-16 Pareth-9, Trideceth-12, Sodium Lactate, Carbomer, Aspartic Acid, Polysorbate 20, Butylene Glycol, Caprylyl Glycol, PEG-8, C11-15 Pareth-7, Guar Hydroxypropyltrimonium Chloride, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Ectoin, Citrate Buffer, Trimethylsiloxyamodimethicone, Phenoxyethanol, Sodium Hydroxide, Ethylhexylglycerin
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCarbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.
A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.
Ectoin is a compound found naturally in some species of bacteria. It can be synthetically created for skincare use.
This ingredient is an osmolyte; Osmolytes help organisms survive osmotic shock (it protects them from extreme conditions). It does this by influencing the properties of biological fluids within cells.
When applied to the skin, ectoin helps bind water molecules to protect our skin. The water forms a sort of armor for the parts of our skin cells, enzymes, proteins, and more.
Besides this, ectoin has many uses in skincare:
A study from 2004 found ectoin to counteract the damage from UV-A exposure at different cell levels. It has also been shown to protect skin against both UV-A, UV-B rays, infrared light, and visible light.
Studies show ectoin to have dual-action pollution protection: first, it protects our skin from further pollution damage. Second, it helps repair damage from pollution.
In fact, ectoin has been shown to help with:
Fun fact: In the EU, ectoin is used in inhalation medication as an anti-pollution ingredient.
Ectoin is a highly stable ingredient. It has a wide pH range of 1-9. Light, oxygen, and temperature do not affect this ingredient.
Learn more about EctoinEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPalmitoyl Tetrapeptide-7 is a lab-made peptide with anti-inflammatory and skin-repairing benefits. It's made up of four amino acids (glycine, glutamine, proline, and arginine) and palmitic acid (which helps it penetrate skin more effectively).
This ingredient helps reduce inflammation by limiting the production of interleukin-6 (IL-6), a chemical that triggers inflammatory responses, particularly after UV exposure.
Less inflammation = slower collagen breakdown and a longer-lasting, youthful appearance.
Palmitoyl Tetrapeptide-7 also stimulates collagen production and supports a healthier skin barrier.
Over time, this can improve skin firmness, hydration, and reduce the appearance of fine lines. Itās commonly paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.
This ingredient has been shown to be effective and safe in cosmetic use and you'll typically find it in small amounts (less than 0.01%).
Due to its palmitic acid base, it may not be safe for Malassezia folliculitis.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tetrapeptide-7Palmitoyl Tripeptide-1 is also known as pal-GHK. It is made up of 3 amino acids and palmitic acid, a fatty acid that helps it absorb into skin more easily.
This peptide is as a signal peptide, meaning it tells the skin to produce more collagen. Collagen is the key protein that helps form the skin's structure and keep it plump, firm, and hydrated.
By boosting collagen production, this ingredient supports a stronger skin barrier and helps reduce the appearance of wrinkles.
You'll most likely see this ingredient paired with Palmitoyl Tetrapeptide-7 in the well-known Matrixyl 3000 complex. While results from in-house testing should be viewed cautiously, this peptide duo is among the most studied and widely used in modern skincare.
Due to its palmitic acid base, this ingredient may not be safe for Malassezia folliculitis.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tripeptide-1Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Phospholipids are naturally found in our skin as they are the main component of cell membranes. Phospholipids have humectant, emollient, antioxidant properties.
Phospholipids are complex lipids that contain glycerin, two fatty acids, and a phosphate group. Some foods that contain phospholipids include soybeans and milk. The phospholipids found in soy come from Lecithin. This ingredient can also be synthetically created.
Due to their hygroscopic nature, they act as both humectants and emollients. Humectants draw moisture from the air to your skin, while emollients help trap moisture in.
The phospholipids in our skin can be naturally depleted. Replenishing the phospholipids in our skin can help hydrate your skin.
Studies show phospholipids display antioxidant activity and may help with reducing the signs of aging.
This ingredient is non-occlusive.
Some types of phospholipids:
Learn more about PhospholipidsPolysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20Sodium PCA is the sodium salt of pyroglutamic acid. It is naturally occurring in our skin's natural moisturizing factors where it works to maintain hydration.
The PCA stands for pyrrolidone carboxylic acid, a natural amino acid derivative.
This ingredient has skin conditioning, anti-inflammatory, and humectant properties. Humectants help hydrate your skin by drawing moisture from the air. This helps keep your skin moisturized.
Learn more about Sodium PCAWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterIngredient Ratings
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Dr. Dennis Gross Skincare DermInfusionsā¢ Fill + Repair Serum 78 ingredients
Paula's Choice Peptide Booster 56 ingredients
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