Versus

Dermalogica Pro-Collagen Banking Serum Versus Peter Thomas Roth Peptide 21 Wrinkle Resist Serum

Serum
Serum
American Brand United States
American Brand United States

Updated on February 06, 2025

Overview

What they are

These products are both reef safe serums. They have a total of 12 ingredients in common

Cool Features

They both contain hyaluronic acid and Vitamin E

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols or parabens

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Pro-Collagen Banking Serum

Water

Skin Conditioning

Pentylene Glycol

Skin Conditioning

Coco-Caprylate/Caprate

Emollient
Not safe for Fungal Acne Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Propanediol

Solvent
Helps hydrate Dry Skin Icon

Simmondsia Chinensis Seed Oil

Emollient
0-2 / 0 Oil IconHelps hydrate Dry Skin IconGood for Scar Healing IconNot safe for Fungal Acne Icon

Trehalose

Humectant
Helps hydrate Dry Skin Icon

Oryza Sativa Bran Water

Masking
Fragrance Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Ethoxydiglycol

Humectant
0 / 0

Triheptanoin

Skin Conditioning

Arginine PCA

Humectant

Diglycerin

Humectant
Helps hydrate Dry Skin Icon

Dipotassium Glycyrrhizate

Humectant
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Collagen Amino Acids

Moisturising
Helps hydrate Dry Skin IconHelps with Anti-Aging Icon

Glycine Soja Oil

Emollient
3 / 0 Oil IconHelps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Citrus Aurantium Dulcis Peel Oil

Masking
Oil Icon

Citrus Aurantium Bergamia Fruit Oil

Masking
Fragrance IconOil Icon

Citrus Paradisi Peel Oil

Masking
Fragrance IconOil Icon

Rosmarinus Officinalis Leaf Extract

Antimicrobial

Cupressus Sempervirens Leaf/Nut/Stem Oil

Emollient
Oil Icon

Santalum Album Oil

Masking
Oil IconMay cause irritation IconEU Allergen Icon

Citrus Limon Peel Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen Icon

Rosa Damascena Flower Oil

Masking
Oil Icon

Jasminum Sambac Flower Extract

Masking
Fragrance Icon

Hydrolyzed Jojoba Esters

Skin Conditioning
Not safe for Fungal Acne Icon

Oryza Sativa Bran Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Aloe Barbadensis Leaf Extract

Emollient
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Tephrosia Purpurea Seed Extract

Skin Conditioning

Helianthus Annuus Extract

Emollient
Helps hydrate Dry Skin Icon

Juniperus Virginiana Oil

Masking
Oil IconMay cause irritation IconEU Allergen Icon

Tagetes Minuta Flower Oil

Masking
Fragrance IconOil Icon

Rosmarinus Officinalis Leaf Oil

Masking
Oil Icon

Cistus Ladaniferus Leaf/Stem Extract

Masking

Hydrolyzed Rice Protein

Skin Conditioning

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Phospholipids

Skin Conditioning
Helps hydrate Dry Skin Icon

Carnosine

Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon

Glyceryl Stearate Citrate

Emollient
Not safe for Fungal Acne Icon

Caprylyl Glycol

Emollient

Polyglutamic Acid

Skin Conditioning
Helps hydrate Dry Skin IconGood for Scar Healing Icon

Glycolipids

Skin Conditioning

Glycine Soja Sterols

Emollient
0 / 0 Helps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Glyceryl Caprylate

Emollient

Sclerotium Gum

Emulsion Stabilising

Polyquaternium-80

Cleansing

Didecyldimonium Chloride

Emulsifying

Dianthus Caryophyllus Flower Extract

Masking
Fragrance Icon

Xanthan Gum

Emulsifying

Methylpropanediol

Solvent

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

PEG-40 Hydrogenated Castor Oil

Emulsifying
Oil IconNot safe for Fungal Acne Icon

Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer

Emulsion Stabilising

Phytic Acid

AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconHelps brighten skin IconMay worsen Rosacea Icon

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Tetrasodium Glutamate Diacetate

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Sodium Hydroxide

Buffering

Sodium Polyacryloyldimethyl Taurate

Emulsion Stabilising

Sodium Benzoate

Masking
Preservative Icon

Potassium Sorbate

Preservative
Preservative Icon

Limonene

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Linalool

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Water, Pentylene Glycol, Coco-Caprylate/Caprate, Glycerin, Propanediol, Simmondsia Chinensis Seed Oil, Trehalose, Oryza Sativa Bran Water, Butylene Glycol, Ethoxydiglycol, Triheptanoin, Arginine PCA, Diglycerin, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Collagen Amino Acids, Glycine Soja Oil, Helianthus Annuus Seed Oil, Citrus Aurantium Dulcis Peel Oil, Citrus Aurantium Bergamia Fruit Oil, Citrus Paradisi Peel Oil, Rosmarinus Officinalis Leaf Extract, Cupressus Sempervirens Leaf/Nut/Stem Oil, Santalum Album Oil, Citrus Limon Peel Oil, Rosa Damascena Flower Oil, Jasminum Sambac Flower Extract, Hydrolyzed Jojoba Esters, Oryza Sativa Bran Extract, Aloe Barbadensis Leaf Extract, Tephrosia Purpurea Seed Extract, Helianthus Annuus Extract, Juniperus Virginiana Oil, Tagetes Minuta Flower Oil, Rosmarinus Officinalis Leaf Oil, Cistus Ladaniferus Leaf/Stem Extract, Hydrolyzed Rice Protein, Tocopheryl Acetate, Tocopherol, Phospholipids, Carnosine, Glyceryl Stearate Citrate, Caprylyl Glycol, Polyglutamic Acid, Glycolipids, Glycine Soja Sterols, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Glyceryl Caprylate, Sclerotium Gum, Polyquaternium-80, Didecyldimonium Chloride, Dianthus Caryophyllus Flower Extract, Xanthan Gum, Methylpropanediol, Cetearyl Alcohol, PEG-40 Hydrogenated Castor Oil, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Phytic Acid, Polysorbate 20, Tetrasodium Glutamate Diacetate, Citric Acid, Sodium Hydroxide, Sodium Polyacryloyldimethyl Taurate, Sodium Benzoate, Potassium Sorbate, Limonene, Linalool

Peptide 21 Wrinkle Resist Serum

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Rosa Centifolia Flower Water

Skin Conditioning

Isopropyl Myristate

Emollient
3-5 / 3 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Mannitol

Humectant
Helps hydrate Dry Skin Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Natto Gum

Tripeptide-10 Citrulline

Skin Conditioning
Peptide Icon

Acetyl Octapeptide-3

Humectant
Peptide IconHelps with Anti-Aging Icon

Palmitoyl Hexapeptide-12

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Acetyl Tetrapeptide-11

Skin Conditioning
Peptide Icon

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging Icon

Acetyl Hexapeptide-1

Skin Conditioning
Peptide Icon

Palmitoyl Oligopeptide

Cleansing
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Acetyl Tetrapeptide-9

Skin Conditioning
Peptide Icon

Acetyl Tetrapeptide-2

Skin Conditioning
Peptide Icon

Tripeptide-1

Skin Conditioning
Peptide IconHelps with Anti-Aging Icon

Palmitoyl Tetrapeptide-7

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Hexapeptide-11

Skin Conditioning
Peptide Icon

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Skin Conditioning
Peptide IconHelps with Anti-Aging Icon

Palmitoyl Tripeptide-5

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Trifluoroacetyl Tripeptide-2

Skin Conditioning
Peptide Icon

Palmitoyl Tripeptide-1

Skin Conditioning
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Sodium Polyglutamate

Humectant

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Retinyl Palmitate

Skin Conditioning
1-3 / 1-3 Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconNot safe for Fungal Acne IconMay worsen Rosacea Icon

Ascorbic Acid

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon

Hydrolyzed Soy Protein

Humectant
Helps hydrate Dry Skin Icon

Hydrolyzed Wheat Protein

Skin Conditioning

Lecithin

Emollient
Helps hydrate Dry Skin Icon

Pseudoalteromonas Ferment Extract

Humectant
Not safe for Fungal Acne Icon

Acrylates Copolymer

Magnesium Chloride

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Dimethyl Isosorbide

Solvent

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Leuconostoc/Radish Root Ferment Filtrate

Antimicrobial
Not safe for Fungal Acne Icon

PEG-8 Dimethicone

Emulsifying
Silicon Icon

Disodium Phosphate

Buffering

Carbomer

Emulsion Stabilising
1 / 0

Dextran

Helps hydrate Dry Skin Icon

Sodium Lactate

Buffering

Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate

Skin Conditioning

Xanthan Gum

Emulsifying

Triethanolamine

Buffering
2 / 0

Sodium Phosphate

Buffering

Octyldodecanol

Emollient

Silica

Abrasive
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon

Sodium Propoxyhydroxypropyl Thiosulfate Silica

Sulfate Icon

Sodium Hydroxide

Buffering

Caprylyl Glycol

Emollient

Potassium Sorbate

Preservative
Preservative Icon

Sodium Benzoate

Masking
Preservative Icon

Phenoxyethanol

Preservative
Preservative Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products. Due to its properties, it can prevent water and oil ingredients from separating.

Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum
Emulsifying

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.

Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.

The lauric acid used to create Polysorbate 20 is often derived from coconuts.

Polysorbate 20 may not be fungal acne safe.

Learn more about Polysorbate 20
Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Learn more about Sodium Hydroxide
Masking, Preservative

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Learn more about Sodium Benzoate
Preservative

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Learn more about Potassium Sorbate

When to use

25 Routines
40% use in am
60% use in pm
96% use every day
19 Routines
53% use in am
47% use in pm
89% use every day