La Roche-Posay Toleriane Double Repair Face Moisturizer Versus Numbuzin No. 5 Daily Multi-Vitamin Cream
This barrier-repair moisturizer is formulated around Squalane and Niacinamide to strengthen the skin barrier and hydrate skin.
This brightening moisturizer is formulated around Panthenol and Niacinamide to brighten dull-looking skin and fade the look of dark spots.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
Humectant
Squalane
Emollient
Dimethicone
Emollient
Zea Mays Starch
Absorbent
Niacinamide
Smoothing
Ammonium Polyacryloyldimethyl Taurate
Emulsion StabilisingMyristyl Myristate
Emollient
Stearic Acid
Cleansing
Ceramide NP
Skin Conditioning
Potassium Cetyl Phosphate
EmulsifyingGlyceryl Stearate Se
Emulsifying
Sodium Hydroxide
BufferingMyristic Acid
Cleansing
Palmitic Acid
Emollient
Capryloyl Glycine
CleansingCaprylyl Glycol
Emollient
Xanthan Gum
EmulsifyingWater, Glycerin, Squalane, Dimethicone, Zea Mays Starch, Niacinamide, Ammonium Polyacryloyldimethyl Taurate, Myristyl Myristate, Stearic Acid, Ceramide NP, Potassium Cetyl Phosphate, Glyceryl Stearate Se, Sodium Hydroxide, Myristic Acid, Palmitic Acid, Capryloyl Glycine, Caprylyl Glycol, Xanthan Gum
Terminalia Ferdinandiana Fruit Extract
Antioxidant
Methylpropanediol
SolventGlycerin
Humectant
Cetyl Ethylhexanoate
EmollientCetearyl Alcohol
Emollient
Panthenol
Skin Conditioning
Niacinamide
Smoothing
Betaine
Humectant
Vinyldimethicone
Squalane
Emollient
Caprylic/Capric Triglyceride
Masking
1,2-Hexanediol
Skin Conditioning
Methyl Trimethicone
Skin Conditioning
Butyrospermum Parkii Butter
Skin Conditioning
Polymethylsilsesquioxane
Propanediol
Solvent
Melia Azadirachta Flower Extract
Skin ConditioningMelia Azadirachta Leaf Extract
Skin ConditioningCurcuma Longa Root Extract
Antioxidant
Ocimum Sanctum Leaf Extract
Skin ConditioningTheobroma Cacao Seed Extract
Antioxidant
Corallina Officinalis Extract
Skin Conditioning
Olea Europaea Leaf Extract
Perfuming
Phaseolus Lunatus Seed Extract
EmollientCitrus Aurantium Dulcis Oil
Masking
Hydrogenated Lecithin
Emulsifying
Citrus Nobilis Peel Oil
Masking
Litsea Cubeba Fruit Oil
Masking
Rosa Canina Fruit Oil
Emollient
Camellia Sinensis Leaf Water
Masking
Water
Skin ConditioningGlyceryl Linolenate
Emollient
Glyceryl Linoleate
Emollient
Tocopheryl Acetate
Antioxidant
Polyglyceryl-2 Stearate
Emulsifying
Isononyl Isononanoate
EmollientGlyceryl Stearate Se
Emulsifying
Glyceryl Stearate
Emollient
Bisabolol
Antioxidant
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingStearyl Alcohol
Emollient
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingTromethamine
BufferingXanthan Gum
Emulsifying3-O-Ethyl Ascorbic Acid
Skin Conditioning
Behenyl Alcohol
Emollient
Ascorbyl Tetraisopalmitate
Antioxidant
Adenosine
Skin Conditioning
Disodium EDTA
Butylene Glycol
Humectant
Sorbitan Isostearate
Emulsifying
Cholesterol
Emollient
Hydroxydecyl Ubiquinone
Antioxidant
Cyamopsis Tetragonoloba Gum
Emulsion StabilisingAgar
MaskingDextrin
AbsorbentCeramide NP
Skin Conditioning
7-Dehydrocholesterol
Emulsion StabilisingMagnesium Myristate
Magnesium Stearate
Cosmetic ColorantSea Salt
Abrasive
Acetyl Glucosamine
Skin Conditioning
Zinc Gluconate
Skin Conditioning
Calcium Stearate
Cosmetic ColorantLactic Acid
Buffering
Cetyl Hydroxyethylcellulose
Emulsion StabilisingRutin
Antioxidant
Ascorbyl Glucoside
Antioxidant
Zinc PCA
Humectant
Glycine
Buffering
Glutamic Acid
Humectant
Glutamine
Skin ConditioningDipotassium Phosphate
BufferingLysine
Skin ConditioningLeucine
Skin ConditioningMethionine
Skin ConditioningValine
MaskingSerine
Masking
Cysteine
Antioxidant
Citrulline
Skin ConditioningAscorbic Acid
Antioxidant
Asparagine
MaskingAspartic Acid
Masking
Isoleucine
Skin ConditioningAlanine
Masking
Arginine
Masking
Ornithine
Skin ConditioningCopper Tripeptide-1
Skin Conditioning
Taurine
BufferingTyrosine
MaskingThreonine
Tryptophan
MaskingPantothenic Acid
Skin ConditioningPhenylalanine
Masking
Proline
Skin Conditioning
Histidine
Humectant
Retinyl Palmitate
Skin Conditioning
Repagermanium
Skin ConditioningLinolenic Acid
Cleansing
Riboflavin
Cosmetic ColorantMagnesium Ascorbyl Phosphate
Antioxidant
Menadione
MaskingBiotin
AntiseborrhoeicBioflavonoids
Skin ConditioningCyanocobalamin
Skin ConditioningSodium Ascorbyl Phosphate
Antioxidant
Tocopherol
Antioxidant
Thiamine Hcl
MaskingPalmitoyl Tetrapeptide-7
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Folic Acid
Skin ConditioningPyridoxine
Skin ConditioningHesperidin
EmollientEthylhexylglycerin
Skin ConditioningLimonene
Perfuming
Citral
Perfuming
Terminalia Ferdinandiana Fruit Extract, Methylpropanediol, Glycerin, Cetyl Ethylhexanoate, Cetearyl Alcohol, Panthenol, Niacinamide, Betaine, Vinyldimethicone, Squalane, Caprylic/Capric Triglyceride, 1,2-Hexanediol, Methyl Trimethicone, Butyrospermum Parkii Butter, Polymethylsilsesquioxane, Propanediol, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Curcuma Longa Root Extract, Ocimum Sanctum Leaf Extract, Theobroma Cacao Seed Extract, Corallina Officinalis Extract, Olea Europaea Leaf Extract, Phaseolus Lunatus Seed Extract, Citrus Aurantium Dulcis Oil, Hydrogenated Lecithin, Citrus Nobilis Peel Oil, Litsea Cubeba Fruit Oil, Rosa Canina Fruit Oil, Camellia Sinensis Leaf Water, Water, Glyceryl Linolenate, Glyceryl Linoleate, Tocopheryl Acetate, Polyglyceryl-2 Stearate, Isononyl Isononanoate, Glyceryl Stearate Se, Glyceryl Stearate, Bisabolol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Stearyl Alcohol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Xanthan Gum, 3-O-Ethyl Ascorbic Acid, Behenyl Alcohol, Ascorbyl Tetraisopalmitate, Adenosine, Disodium EDTA, Butylene Glycol, Sorbitan Isostearate, Cholesterol, Hydroxydecyl Ubiquinone, Cyamopsis Tetragonoloba Gum, Agar, Dextrin, Ceramide NP, 7-Dehydrocholesterol, Magnesium Myristate, Magnesium Stearate, Sea Salt, Acetyl Glucosamine, Zinc Gluconate, Calcium Stearate, Lactic Acid, Cetyl Hydroxyethylcellulose, Rutin, Ascorbyl Glucoside, Zinc PCA, Glycine, Glutamic Acid, Glutamine, Dipotassium Phosphate, Lysine, Leucine, Methionine, Valine, Serine, Cysteine, Citrulline, Ascorbic Acid, Asparagine, Aspartic Acid, Isoleucine, Alanine, Arginine, Ornithine, Copper Tripeptide-1, Taurine, Tyrosine, Threonine, Tryptophan, Pantothenic Acid, Phenylalanine, Proline, Histidine, Retinyl Palmitate, Repagermanium, Linolenic Acid, Riboflavin, Magnesium Ascorbyl Phosphate, Menadione, Biotin, Bioflavonoids, Cyanocobalamin, Sodium Ascorbyl Phosphate, Tocopherol, Thiamine Hcl, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Folic Acid, Pyridoxine, Hesperidin, Ethylhexylglycerin, Limonene, Citral
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Learn more about Ceramide NPGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinGlyceryl Stearate Se is a self-emulsifying (SE) form of glyceryl stearate. Self-emusifying means this ingredient automatically blends with water. It is an emulsifier, emollient, and cleansing agent.
As an emulsifier, Glyceryl Stearate Se prevents ingredients such as oil and water from separating. It is also a surfactant, meaning it helps cleanse the skin. Surfactants help gather oil, dirt, and other pollutants so they may be rinsed away easily.
Emollients help your skin stay smooth and soft. It does so by creating a film on top of the skin that helps trap moisture in.
Learn more about Glyceryl Stearate SeNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideSqualane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Learn more about SqualaneWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum
