Versus

Dear, Klairs Midnight Blue Calming Cream Versus Neogen Sur.Medic+ Azulene Soothing Peptide Ampoule

General Moisturizer
Ampoule
Korean Brand South Korea
Korean Brand South Korea

Updated on June 03, 2024

Overview

Cool Features

They both contain ceramides, hyaluronic acid and peptides

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, scar healing and dark spots

Free From

They both do not contain any parabens or sulfates

What's Inside

They both contain fragrances and oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside

What's inside

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Midnight Blue Calming Cream
Sur.Medic+ Azulene Soothing Peptide Ampoule

Water

Skin Conditioning

Dipropylene Glycol

Humectant

Isopentyldiol

Humectant
Helps hydrate Dry Skin Icon

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Polydecene

Skin Conditioning

Adenosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing Icon

Guaiazulene

Antimicrobial
Fragrance Icon

Copper Tripeptide-1

Skin Conditioning
Peptide IconHelps hydrate Dry Skin IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Scar Healing Icon

Tripeptide-1

Skin Conditioning
Peptide IconHelps with Anti-Aging Icon

Palmitoyl Tripeptide-1

Skin Conditioning
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Tripeptide-2

Skin Conditioning
Peptide IconHelps with Anti-Aging IconGood for Dark Spots Icon

Hexapeptide-11

Skin Conditioning
Peptide Icon

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging Icon

Palmitoyl Tetrapeptide-7

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Palmitoyl Pentapeptide-4

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Hexapeptide-9

Skin Conditioning
Peptide Icon

Nonapeptide-1

Skin Conditioning
Peptide Icon

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Betula Platyphylla Japonica Juice

Skin Conditioning
Helps hydrate Dry Skin Icon

Glycyrrhiza Glabra Root Extract

Bleaching
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Camellia Japonica Seed Extract

Skin Conditioning

Artemisia Asiatica Extract

Skin Conditioning

Camellia Japonica Flower Extract

Emollient

Aloe Barbadensis Leaf Extract

Emollient
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Calendula Officinalis Extract

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon

Chamomilla Recutita Extract

Skin Conditioning
0 / 0 Helps reduce Skin Redness IconHelps reduce irritation Icon

Propolis Extract

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing IconHelps fight Acne Icon

Phellinus Linteus Extract

Skin Conditioning

Oenothera Biennis Oil

Emollient
3 / 2 Oil IconHelps reduce irritation IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Simmondsia Chinensis Seed Oil

Emollient
0-2 / 0 Oil IconHelps hydrate Dry Skin IconGood for Scar Healing IconNot safe for Fungal Acne Icon

Cupressus Sempervirens Oil

Masking
Oil Icon

Zinc Oxide

Cosmetic Colorant
1 / 0 Mineral UV Filter IconHelps fight Acne IconNon-Reef-Safe Icon

Beta-Glucan

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging IconGood for Scar Healing Icon

Asiaticoside

Antioxidant
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Madecassic Acid

Skin Conditioning
Helps reduce irritation IconHelps with Anti-Aging Icon

Asiatic Acid

Skin Conditioning

Lavandula Angustifolia Flower Extract

Cleansing
May cause irritation IconEU Allergen Icon

Madecassoside

Antioxidant
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

Camellia Sinensis Seed Oil

Humectant
Oil IconHelps hydrate Dry Skin IconHelps reduce irritation IconNot safe for Fungal Acne Icon

Camellia Japonica Leaf Extract

Skin Conditioning

Butyrospermum Parkii Butter

Skin Conditioning
Helps hydrate Dry Skin IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Persea Gratissima Oil

Skin Conditioning
0-3 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Mentha Rotundifolia Leaf Extract

Tonic

Calamine

Absorbent

Melaleuca Alternifolia Leaf Oil

Antioxidant
Antioxidant IconFragrance IconOil IconHelps hydrate Dry Skin IconGood for Oily Skin IconMay worsen Eczema Icon

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Artemisia Capillaris Extract

Alcohol Denat.

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Octyldodeceth-16

Emulsifying

Carbomer

Emulsion Stabilising
1 / 0

Tromethamine

Buffering

Cellulose Gum

Emulsion Stabilising
0 / 0

Phenyl Trimethicone

Skin Conditioning
Silicon Icon

Ethylhexylglycerin

Skin Conditioning

Acacia Senegal Gum

Masking

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Agar

Masking

Mannitol

Humectant
Helps hydrate Dry Skin Icon

Zea Mays Starch

Absorbent

Lavandula Angustifolia Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen Icon

Microcrystalline Cellulose

Absorbent

Disodium EDTA

Gardenia Florida Fruit Extract

Skin Conditioning

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin Icon

Maltodextrin

Absorbent
Helps hydrate Dry Skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Lecithin

Emollient
Helps hydrate Dry Skin Icon

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Sodium Ascorbyl Phosphate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Hydrogen Dimethicone

Silicon Icon

Water, Dipropylene Glycol, Isopentyldiol, 1,2-Hexanediol, Polydecene, Adenosine, Guaiazulene, Copper Tripeptide-1, Tripeptide-1, Palmitoyl Tripeptide-1, Tripeptide-2, Hexapeptide-11, Acetyl Hexapeptide-8, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Hexapeptide-9, Nonapeptide-1, Ceramide NP, Betula Platyphylla Japonica Juice, Glycyrrhiza Glabra Root Extract, Camellia Sinensis Leaf Extract, Camellia Japonica Seed Extract, Artemisia Asiatica Extract, Camellia Japonica Flower Extract, Aloe Barbadensis Leaf Extract, Calendula Officinalis Extract, Chamomilla Recutita Extract, Propolis Extract, Phellinus Linteus Extract, Oenothera Biennis Oil, Simmondsia Chinensis Seed Oil, Cupressus Sempervirens Oil, Zinc Oxide, Beta-Glucan, Asiaticoside, Madecassic Acid, Asiatic Acid, Lavandula Angustifolia Flower Extract, Madecassoside, Camellia Sinensis Seed Oil, Camellia Japonica Leaf Extract, Butyrospermum Parkii Butter, Persea Gratissima Oil, Allantoin, Mentha Rotundifolia Leaf Extract, Calamine, Melaleuca Alternifolia Leaf Oil, Panthenol, Artemisia Capillaris Extract, Alcohol Denat., Butylene Glycol, Octyldodeceth-16, Carbomer, Tromethamine, Cellulose Gum, Phenyl Trimethicone, Ethylhexylglycerin, Acacia Senegal Gum, Sodium Hyaluronate, Agar, Mannitol, Zea Mays Starch, Lavandula Angustifolia Oil, Microcrystalline Cellulose, Disodium EDTA, Gardenia Florida Fruit Extract, Hydrogenated Lecithin, Maltodextrin, Glycerin, Caprylic/Capric Triglyceride, Lecithin, Polysorbate 20, Sodium Ascorbyl Phosphate, Hydrogen Dimethicone

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Humectant, Skin Conditioning

Acetyl Hexapeptide-8, commonly known as Argireline or Acetyl Hexapeptide-3, is a popular peptide in skincare. It’s often referred to as a “Botox-like” ingredient because it helps reduce muscle movement.

By relaxing these micro-movements, Argireline may help minimize the appearance of fine lines and wrinkles. That said, it’s not as powerful as Botox, and research on its long-term effectiveness is still limited.

Beyond smoothing, Argireline may also support collagen production. Collagen is the protein that helps keep your skin firm, bouncy, and well-hydrated by strengthening the skin barrier.

So while Argireline isn’t a miracle fix, it can be a helpful addition to a routine focused on both prevention and skin health.

Read more about other common types of peptides here:

Learn more about Acetyl Hexapeptide-8
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Skin Conditioning

Butyrospermum Parkii Butter is a plant lipid from the fruit of the Shea Tree. It is an effective skin hydrator and emollient.

Emollients help soothe and soften your skin. It does this by creating a protective film on your skin. This barrier helps trap moisture and keeps your skin hydrated. Emollients may be effective at treating dry or itchy skin.

Shea butter is rich in antioxidants. Antioxidants help fight free-radicals, or molecules that may harm the body. It is also full of fatty acids including stearic acid and linoleic acid. These acids help replenish the skin and keep skin moisturized.

While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.

Shea butter may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.

Learn more about Butyrospermum Parkii Butter
Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride
Skin Conditioning

Ceramide NP is a type of ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here:
Ceramide AP
Ceramide EOP

Learn more about Ceramide NP
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Antimicrobial, Perfuming

Guaiazulene is a fragrance.

Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.

This ingredient has emollient and emulsifying properties.

As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.

As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.

This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.

Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.

We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.

Some other names for this ingredient include soy lecithin and deoiled soy lecithin.

Learn more about Lecithin
Emollient, Skin Conditioning

This oil comes from the seeds of the desert shrub called Jojoba. It is more commonly known as jojoba oil, a non-comedogenic oil.

Jojoba oil does not contain fragrance and has many fatty-acids, making it a great soothing ingredient.

It also contains Vitamin E, a great moisturizing ingredient. Vitamin E is also an antioxidant and protects your skin against oxidative damage.

This ingredient humectant properties, meaning it helps draw moisture from the air. This helps keep your skin hydrated.

While jojoba has antibacterial properties, it is only able to kill some strains of bacteria.

Studies also show it helps in wound healing. In fact, Indigenous cultures have used jojoba as a moisturizer and to help treat burns for centuries.

Fun fact: Jojoba oil similar to natural human skin sebum, so it has a great effect on dry skin. It is also promising with helping to regulate sebum production.

Due to its fatty acid content, Jojoba oil may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.

Learn more about Simmondsia Chinensis Seed Oil
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Masking, Buffering

Tromethamine helps balance the pH and improve the texture of a product. It is synthetically created.

As an emulsifier, Tromethamine prevents oil and water ingredients from separating. This helps stabilize the product and elongate a product's shelf life. Tromethamine also makes a product thicker.

Tromethamine helps balance the pH level of a product. Normal pH level of skin is slightly acidic (~4.75-5.5). The acidity of our skin is maintained by our glands and skin biome. Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.

Oral Tromethanmine is an anti-inflammatory drug but plays the role of masking, adding fragrance, and/or balancing pH in skincare.

1,3-Propanediol, 2-amino-2-(hydroxymethyl)-

Learn more about Tromethamine
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

543 Routines
23% use in am
77% use in pm
86% use every day
When to use See routines that use it ->
18 Routines
39% use in am
61% use in pm
83% use every day

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Works Well 68% Hydrating 47% Absorbs Well 37%
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