Anua 3 Ceramide Panthenol Moisture Barrier Cream Versus The Ordinary Natural Moisturizing Factors + HA
This barrier-repair moisturizer is formulated around Panthenol and Centella Asiatica Extract to strengthen the skin barrier and hydrate skin.
This barrier-repair moisturizer is formulated around Sodium Hyaluronate and Arginine to strengthen the skin barrier and hydrate skin.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningPanthenol
Skin ConditioningButylene Glycol
HumectantPropanediol
SolventCaprylic/Capric Triglyceride
MaskingGlycerin
HumectantCetyl Ethylhexanoate
EmollientBehenyl Alcohol
EmollientOctyldodecanol
EmollientPhenyl Trimethicone
Skin ConditioningVinyldimethicone
1,2-Hexanediol
Skin ConditioningBis-Diglyceryl Polyacyladipate-2
EmollientPentylene Glycol
Skin ConditioningCaprylyl Methicone
Skin ConditioningCentella Asiatica Extract
CleansingPolyglyceryl-3 Methylglucose Distearate
EmulsifyingBetaine
HumectantC14-22 Alcohols
Emulsion StabilisingCeramide NP
Skin ConditioningPhytosterols
Skin ConditioningHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingHydrogenated Rice Bran Oil
Skin ConditioningC12-20 Alkyl Glucoside
EmulsifyingAmmonium Acryloyldimethyltaurate/Vp Copolymer
Glyceryl Stearate
EmollientDimethiconol
EmollientGlyceryl Caprylate
EmollientSodium Stearoyl Glutamate
CleansingHydrogenated Lecithin
EmulsifyingGlyceryl Glucoside
HumectantAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingTromethamine
BufferingSodium Phytate
Polyglyceryl-10 Stearate
Skin ConditioningEthylhexylglycerin
Skin ConditioningSodium Hyaluronate
HumectantEthylhexyl Olivate
Skin ConditioningDipropylene Glycol
HumectantSodium Acrylates Copolymer
Polyglyceryl-4 Oleate
EmulsifyingLinolenic Acid
CleansingPolyglyceryl-10 Laurate
Skin ConditioningSphingolipids
EmollientPhosphatidylcholine
Emulsifying4-Terpineol
MaskingAllantoin
Skin ConditioningEctoin
Skin ConditioningHyaluronic Acid
HumectantSqualane
EmollientLecithin
EmollientAsiaticoside
AntioxidantEscin
TonicMadecassic Acid
Skin ConditioningAsiatic Acid
Skin ConditioningBeta-Sitosterol
Emulsion StabilisingTremella Fuciformis Extract
HumectantCeramide AP
Skin ConditioningCeramide EOP
Skin ConditioningGlycine
BufferingGlutamic Acid
HumectantSerine
MaskingAlanine
MaskingLysine
Skin ConditioningArginine
MaskingProline
Skin ConditioningThreonine
Water, Panthenol, Butylene Glycol, Propanediol, Caprylic/Capric Triglyceride, Glycerin, Cetyl Ethylhexanoate, Behenyl Alcohol, Octyldodecanol, Phenyl Trimethicone, Vinyldimethicone, 1,2-Hexanediol, Bis-Diglyceryl Polyacyladipate-2, Pentylene Glycol, Caprylyl Methicone, Centella Asiatica Extract, Polyglyceryl-3 Methylglucose Distearate, Betaine, C14-22 Alcohols, Ceramide NP, Phytosterols, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydrogenated Rice Bran Oil, C12-20 Alkyl Glucoside, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Glyceryl Stearate, Dimethiconol, Glyceryl Caprylate, Sodium Stearoyl Glutamate, Hydrogenated Lecithin, Glyceryl Glucoside, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Sodium Phytate, Polyglyceryl-10 Stearate, Ethylhexylglycerin, Sodium Hyaluronate, Ethylhexyl Olivate, Dipropylene Glycol, Sodium Acrylates Copolymer, Polyglyceryl-4 Oleate, Linolenic Acid, Polyglyceryl-10 Laurate, Sphingolipids, Phosphatidylcholine, 4-Terpineol, Allantoin, Ectoin, Hyaluronic Acid, Squalane, Lecithin, Asiaticoside, Escin, Madecassic Acid, Asiatic Acid, Beta-Sitosterol, Tremella Fuciformis Extract, Ceramide AP, Ceramide EOP, Glycine, Glutamic Acid, Serine, Alanine, Lysine, Arginine, Proline, Threonine
Water
Skin ConditioningCaprylic/Capric Triglyceride
MaskingCetyl Alcohol
EmollientPropanediol
SolventStearyl Alcohol
EmollientGlycerin
HumectantSodium Hyaluronate
HumectantArginine
MaskingAspartic Acid
MaskingGlycine
BufferingAlanine
MaskingSerine
MaskingValine
MaskingIsoleucine
Skin ConditioningProline
Skin ConditioningThreonine
Histidine
HumectantPhenylalanine
MaskingGlucose
HumectantMaltose
MaskingFructose
HumectantTrehalose
HumectantSodium PCA
HumectantPCA
HumectantSodium Lactate
BufferingUrea
BufferingAllantoin
Skin ConditioningLinoleic Acid
CleansingOleic Acid
EmollientPhytosteryl Canola Glycerides
Skin ConditioningPalmitic Acid
EmollientStearic Acid
CleansingLecithin
EmollientTriolein
Skin ConditioningTocopherol
AntioxidantCarbomer
Emulsion StabilisingIsoceteth-20
EmulsifyingPolysorbate 60
EmulsifyingSodium Chloride
MaskingCitric Acid
BufferingTrisodium Ethylenediamine Disuccinate
Pentylene Glycol
Skin ConditioningTriethanolamine
BufferingSodium Hydroxide
BufferingPhenoxyethanol
PreservativeChlorphenesin
AntimicrobialWater, Caprylic/Capric Triglyceride, Cetyl Alcohol, Propanediol, Stearyl Alcohol, Glycerin, Sodium Hyaluronate, Arginine, Aspartic Acid, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Glucose, Maltose, Fructose, Trehalose, Sodium PCA, PCA, Sodium Lactate, Urea, Allantoin, Linoleic Acid, Oleic Acid, Phytosteryl Canola Glycerides, Palmitic Acid, Stearic Acid, Lecithin, Triolein, Tocopherol, Carbomer, Isoceteth-20, Polysorbate 60, Sodium Chloride, Citric Acid, Trisodium Ethylenediamine Disuccinate, Pentylene Glycol, Triethanolamine, Sodium Hydroxide, Phenoxyethanol, Chlorphenesin
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Alanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.
Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Learn more about AllantoinArginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Learn more about ArginineCaprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinGlycine is the smallest amino acid and a key building block of collagen. It's part if your skin's Natural Moisturizing Factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
A study from 2022 found that an amino acid complex featuring taurine, arginine, and glycine significantly reduced skin irritation, improved redness, and accelerated the skin repair process.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Learn more about LecithinPentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolProline is a non-essential amino acid, meaning your body can make it on its own. In skincare, it is a skin conditioning ingredient that keeps skin soft and hydrated.
It makes up about 23% of the collagen molecule (collagen is the protein responsible for keeping your skin firm) and is involved in your skin's natural hyaluronic acid production. When applied topically, proline can penetrate the skin fairly well due to its small molecular size.
Reviews of this ingredient have found it to be neither a dermal irritant nor a sensitizer.
Fun fact: Proline can be found in protein-rich foods like meat, fish, eggs, and dairy.
Learn more about ProlinePropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolSerine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.
Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.
Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.
Learn more about SerineSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateThreonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.
Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water