Sesderma Sesretinal Mature Skin Facial Gel Cream - Russia Versus Sesderma Azelac Ru Crema Gel
Updated on February 23, 2025
Overview
What they are
These products are both cruelty-free general moisturizers. They have a total of 40 ingredients in common
Cool Features
They both contain exfoliants, peptides, retinoid, Vitamin C and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any common allergens or parabens
What's Inside
They both contain harsh alcohols, fragrances, oils and silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Sesderma Sesretinal Mature Skin Facial Gel Cream 66 ingredients
Sesderma Azelac Ru Crema Gel 68 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
Sesderma Sesretinal Mature Skin Facial Gel Cream 66 ingredients
Sesderma Azelac Ru Crema Gel 68 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Alcohol comes in many different forms. Different types of alcohol will have different effects on skin. This ingredient is usually an astringent alcohol.
These alcohols are drying on the skin. They may strip away your skin's natural oils and even damage your skin barrier. Astringent alcohols may also irritate skin.
Other types of astringent alcohols include:
According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients.
Any type of sanitizing product will have high amounts of alcohol to help kill bacteria and viruses.
Fatty alcohols come from plant oils such as coconut oil. These can help hydrate the skin and are non-irritating. Some fatty alcohols include cetyl and stearyl alcohol.
Learn more about AlcoholArachidyl Alcohol is a fatty alcohol made from peanut oil. It is an emollient, emulsifier, and thickener.
You'll most likely find this ingredient as an emulsifier in water-based cosmetics.
We don't have a description for Arachidyl Glucoside yet.
Ascorbyl Palmitate is created by combining pure Vitamin C and palmitic acid. It is an antioxidant and helps reduce hyperpigmentation.
This ingredient is a more stable version of Vitamin C, meaning it does not disintegrate as quickly when exposed to sunlight. However, studies show it does not penetrate skin as well as pure Vitamin C.
Ascorbyl Palmitate is oil soluble.
Read more about other types of Vitamin C:
Learn more about Ascorbyl PalmitateBakuchiol is a plant-derived antioxidant (it's vegan!). It is often called the replacement for retinol although it is not part of the same family.
It has similar effects as retinol: skin smoothing, reducing discoloration, and preventing wrinkles. It does not cause as much irritation as traditional retinoids.
Bakuchiol works by breaking down free radicals and stimulating collagen production in skin.
Combining bakuchiol with retinol will not have adverse side effects. Studies show using them will just boost the benefits. Bakuchiol is also found to help stabilize retinol.
While bakuchiol does not make the skin more sun sensitive, we recommend wearing SPF on a daily basis.
Read more about traditional retinol
Learn more about BakuchiolBehenyl Alcohol is a type of fatty alcohol (these are different from the drying, solvent alcohols).
Fatty Alcohols have hydrating properties and are most often used as an emollient or to thicken a product. They are usually derived from natural fats and oils; behenyl alcohol is derived from the fats of vegetable oils.
Emollients help keep your skin soft and hydrated by creating a film that traps moisture in.
In 2000, Behenyl Alcohol was approved by the US as medicine to reduce the duration of cold sores.
Learn more about Behenyl AlcoholCitric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.
If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.
Read more about some other popular AHA's here:
Learn more about Citric AcidDimethicone is a type of synthetic silicone created from natural materials such as quartz.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeThis ingredient is a silicone used to improve the texture of products and absorb oil. It does not get absorbed into the skin.
Like other silicones, Dimethicone/Vinyl Dimethicone Crosspolymer helps condition the skin by creating a barrier. In this sense, it can act as an emollient and trap moisture in.
This ingredient is a type of elastomer.
Learn more about Dimethicone/Vinyl Dimethicone CrosspolymerDipotassium Phosphate is an inorganic salt. This just means it has a different structure than organic salts. It is a stabilizing and pH adjusting ingredient.
This ingredient is soluble in water.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTAEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinGlyceryl Oleate is the ester of glycerin and oleic acid. This ingredient is mainly an emollient and emulsifier.
Emollients soften and hydrate the skin by creating a thin film on top to trap in moisture. As an emulsifier, glyceryl oleate helps stabilize formulations by preventing ingredients such as oil and water from separating. According to a manufacturer, this ingredient helps helps thicken water-in-oil formulations, shower gels, and hair shampoos.
In some products, this ingredient may be used as a fragrance / perfuming ingredient. The scent of this ingredient is described to be "waxy".
Glyceryl oleate is created from oils rich in oleic acid, such as peanut oil and olive oil.
This ingredient may not be malassezia folliculitis safe.
Learn more about Glyceryl OleateGlyceryl Stearate is a mix of glycerin and stearic acid.
It is used to stabilize the mixing of water and oil ingredients. By preventing these ingredients from separating, it can help elongate shelf life. It can also help thicken the product's texture.
As an emollient, it helps soften skin and supports barrier-replenishing ingredients.
In cosmetics, Glyceryl Stearate is often made from vegetable oils or synthetically produced.
This ingredient may not be fungal-acne safe
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearateGlycyrrhetinic acid is a compound found in licorice. It has skin conditioning, skin soothing, antibacterial, and antioxidant properties.
Not only is this a great ingredient for soothing inflammation, studies show this compound is effective at protecting skin against UV-B induced damage.
Fun fact: This ingredient is also used to mask the bitter taste of medicine.
Learn more about Glycyrrhetinic AcidHydrochloric Acid can be found in the human body. It used to adjust pH levels of basic solutions.
We don't have a description for Isoceteth-10 yet.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.
This ingredient has emollient and emulsifying properties.
As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.
As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.
This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.
Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.
We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.
Learn more about LecithinNiacin is the other form of B3, with the other being niacinamide. The two have similar skin benefits: reducing inflammation, strengthening the skin barrier, and fading dark spots.
Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1 is a peptide.
We don't have a description for Nicotiana Benthamiana Sh-Polypedtide-7 yet.
Paraffinum Liquidum is also known as liquid paraffin. It is a type of highly refined mineral oil.
Like other oils, Paraffinum Liquidum has emollient properties. Emollients help soothe and soften the skin. By creating a barrier to trap moisture within, emollients help keep your skin hydrated.
Paraffinum Liquidum does not irritate the skin and is non-comedogenic.
Learn more about Paraffinum LiquidumParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
We don't have a description for Polysilicone-11 yet.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20Potassium Phosphate is the term for the salts of potassium and phosphate ions. Our bodies naturally create and use potassium phosphate.
In cosmetics, potassium phosphate is used to adjust the pH level of products. Our skin has a natural pH level. Maintaining this pH level is important for our skin barrier. If the skin barrier is disrupted, our skin can experience dehydration and irritation.
This ingredient is used in medicine to help treat low blood levels of phosphorus.
Learn more about Potassium PhosphatePotassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Learn more about Potassium SorbatePropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolSilica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.
Silica is often used for absorption and can help reduce shine when products are applied. Silica occurs in naturally in materials like clay and sandstone, and it can also be produced synthetically.
Silica is present naturally within the skin during collagen production and when reducing inflammation.
Learn more about SilicaChances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt.
This ingredient has many purposes in skincare: thickener, emulsifier, and exfoliator.
You'll most likely find this ingredient in cleansers where it is used to create a gel-like texture. As an emulsifier, it also prevents ingredients from separating.
There is much debate on whether this ingredient is comedogenic. The short answer - comedogenic ratings don't tell the whole story. Learn more about comegodenic ratings here.
The concensus about this ingredient causing acne seems to be divided. Research is needed to understand if this ingredient does cause acne.
Scrubs may use salt as the primary exfoliating ingredient.
Learn more about Sodium ChlorideWe don't have a description for Sodium Cholate yet.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateThis ingredient is extracted from the germ part of the wheat plant. The germ of a plant refers to the seed embryo, or part that sprouts into a new plant.
Some studies have found wheat germ to help with wound healing.
Tromethamine helps balance the pH and improve the texture of a product. It is synthetically created.
As an emulsifier, Tromethamine prevents oil and water ingredients from separating. This helps stabilize the product and elongate a product's shelf life. Tromethamine also makes a product thicker.
Tromethamine helps balance the pH level of a product. Normal pH level of skin is slightly acidic (~4.75-5.5). The acidity of our skin is maintained by our glands and skin biome. Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.
Oral Tromethanmine is an anti-inflammatory drug but plays the role of masking, adding fragrance, and/or balancing pH in skincare.
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
Learn more about TromethamineWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumIngredient Ratings
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