Sesderma Azelac Ru Crema Gel Versus ISDIN Isdinceutics Retinal Intense Serum
Updated on February 08, 2024
Overview
What they are
These products are both cruelty-free and reef safe . They have a total of 16 ingredients in common
Cool Features
They both contain exfoliants, peptides, retinoid, Vitamin C and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any common allergens, parabens or sulfates
What's Inside
They both contain harsh alcohols, fragrances and silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Sesderma Azelac Ru Crema Gel 68 ingredients
ISDIN Isdinceutics Retinal Intense Serum 41 ingredients
At a glance
Click on any of the items below to learn more
Sesderma Azelac Ru Crema Gel 68 ingredients
ISDIN Isdinceutics Retinal Intense Serum 41 ingredients
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Concerns
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Ingredients Side-by-side
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.
2 Concerns
Paraffinum Liquidum is also known as liquid paraffin. It is a type of highly refined mineral oil.
Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.
Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.
Arachidyl Alcohol is a fatty alcohol made from peanut oil. It is an emollient, emulsifier, and thickener.
5 Concerns
Alcohol comes in many different forms. Different types of alcohol will have different effects on skin. This ingredient is usually an astringent alcohol.
Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
Tranexamic Acid is best used for treating hyperpigmentation, discoloration, and melasma. It can also help build a stronger skin barrier.
8 Benefits 3 Concerns
Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
7 Benefits 3 Concerns
Retinal is a form of retinoid. Retinoids are the gold-standard class of anti-aging ingredients.
Not safe for Fungal Acne
Palmitoyl Tripeptide-5 isn't fungal acne safe and is a peptide.
Niacin is the other form of B3, with the other being niacinamide. The two have similar skin benefits: reducing inflammation, strengthening the skin barrier, and fading dark spots.
3 Benefits
Bakuchiol is a plant-derived antioxidant (it's vegan!). It is often called the replacement for retinol although it is not part of the same family.
Azelaic acid is a naturally occurring acid derived from grains. This ingredient is effective in treating acne, rosacea, and other skin conditions.
Antioxidant 6 Benefits
Ascorbyl Glucoside is a stable form of Vitamin C. It is created by combining glucose from starch.
5 Benefits
You might know this ingredient as Ethyl Ascorbic Acid, a more stable version of ascorbic acid.
Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1 is a peptide.
Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76 is a peptide.
Dimethicone/Vinyl Dimethicone Crosspolymer is a silicone used to improve the texture of products and absorb oil. It does not get absorbed into the skin.
A type of fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product. They are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as traditional alcohols.
This ingredient is extracted from the germ part of the wheat plant. The germ of a plant refers to the seed embryo, or part that sprouts into a new plant.
Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.
Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
Cyclohexasiloxane is a type of silicone more commonly known as D6. It is an emollient and solvent.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
BHT is a synthetic antioxidant. As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
Antioxidant Helps brighten skin
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
Antioxidant 4 Benefits May cause irritation
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Glyceryl Stearate is a mix of glycerin and stearic acid.
Antioxidant 6 Benefits Not safe for Fungal Acne
Ascorbyl Palmitate is created by combining pure Vitamin C and palmitic acid. It is an antioxidant and helps reduce hyperpigmentation.
2 Concerns
Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.
Chances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt.
Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
Not safe for Fungal Acne
Glyceryl Oleate is a fragrance and isn't fungal acne safe.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Decyl Glucoside is a glucose-based surfactant. Surfactants help clean the skin by trapping oil, sebum, and dirt to be washed away.
4 Benefits 2 Concerns
Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
Tromethamine is an aliphatic compound. An aliphatic compound is an organic compound with open-chained carbon atoms. It is synthetically created. Tromethamine is used to balance pH and improve texture.
This BHA stands for butylated hydroxyanisole. If you are looking for the beta-hydroxy acid, aka as Salicylic Acid, click here.
Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
Dipotassium Phosphate is an inorganic salt. This just means it has a different structure than organic salts. It is a stabilizing and pH adjusting ingredient.
Potassium Phosphate is the term for the salts of potassium and phosphate ions. Our bodies naturally create and use potassium phosphate.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
2 Concerns
Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Water, Propanediol, Paraffinum Liquidum, Cyclopentasiloxane, Lecithin, Arachidyl Alcohol, Alcohol, Cetyl Alcohol, Undecylenoyl Phenylalanine, Tranexamic Acid, Retinol, Retinal, Palmitoyl Tripeptide-5, Nicotiana Benthamiana Sh-Polypedtide-7, Niacin, Morus Alba Root Extract, Glycyrrhetinic Acid, Diacetyl Boldine, Bellis Perennis Flower Extract, Bakuchiol, Azelaic Acid, Ascorbyl Glucoside, 4-Butylresorcinol, 3-O-Ethyl Ascorbic Acid, Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1, Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-2, Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76, Dimethicone/Vinyl Dimethicone Crosspolymer, Behenyl Alcohol, Arachidyl Glucoside, Triticum Vulgare Germ Extract, Propylene Glycol, Carbomer, Cyclohexasiloxane, Xanthan Gum, Dimethicone, Polysorbate 20, Citrus Grandis Fruit Extract, Sodium Cholate, Polysilicone-11, Sodium Hydroxide, Butylene Glycol, BHT, Tocopheryl Acetate, Disodium EDTA, Tocopherol, Glyceryl Stearate, Ascorbyl Palmitate, Silica, Sodium Chloride, Isoceteth-10, Caprylic/Capric Triglyceride, Glyceryl Oleate, Glycerin, Decyl Glucoside, Citric Acid, Tromethamine, Hydrochloric Acid, BHA, Hexylene Glycol, Caprylyl Glycol, Dipotassium Phosphate, Hydroxypropyl Cyclodextrin, Potassium Phosphate, Phenoxyethanol, Ethylhexylglycerin, Potassium Sorbate, Parfum
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.
Dibutyl Adipate is an emollient and solvent. It is created from butyl alcohol and adipic acid.
6 Benefits
Niacinamide has emerged as an all-star ingredient due to its many benefits.
Isoamyl Laurate is created from isoamyl alcohol and lauric acid. It is an emollient and traps moisture underneath.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.
Dimethicone/Vinyl Dimethicone Crosspolymer is a silicone used to improve the texture of products and absorb oil. It does not get absorbed into the skin.
5 Concerns
Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.
3 Benefits
Bakuchiol is a plant-derived antioxidant (it's vegan!). It is often called the replacement for retinol although it is not part of the same family.
1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.
Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
Hydroxyacetophenone is antioxidant and helps with skin conditioning.
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate (long name, huh?) is a synthetic antioxidant.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
2 Concerns
Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Antioxidant Helps brighten skin
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
Antioxidant 4 Benefits May cause irritation
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
4 Benefits 2 Concerns
Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
Maltodextrin is a polysaccharide. It is derived from starch such as rice, corn, wheat, or potato starch.
7 Benefits 3 Concerns
Retinal is a form of retinoid. Retinoids are the gold-standard class of anti-aging ingredients.
2 Concerns
Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
Phospholipids are naturally found in our skin as they are the main component of cell membranes. Phospholipids have humectant, emollient, antioxidant properties.
Synthetic Fluorphlogopite is the synthethic version of mica. It consists of fluorine, aluminum and silicate.
Ci 77891 is a white pigment from Titanium dioxide. It is naturally found in minerals such as rutile and ilmenite.
Antioxidant 6 Benefits
Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.
Fragrance
T-Butyl Alcohol it is most commonly used as a solvent.
Rosmarinus Officinalis Leaf Extract comes from rosemary. Rosemary is native to the Mediterranean.
Not safe for Fungal Acne
Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.
Tin Oxide is an inorganic oxide used to add opacity and volume to a product. In nature, it is already found in mineral form. The main ore of tin is an opaque and shiny mineral called casseterite.
Water, Dimethicone, Dibutyl Adipate, Niacinamide, Isoamyl Laurate, Lauryl Peg/Ppg-18/18 Methicone, Glycerin, Propanediol, Dimethicone/Vinyl Dimethicone Crosspolymer, Alcohol Denat., Bakuchiol, 1,2-Hexanediol, Pentylene Glycol, Caprylic/Capric Triglyceride, Ethylcellulose, Hydroxyacetophenone, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, 4-T-Butylcyclohexanol, Caprylyl Glycol, Parfum, Sodium Acrylates Crosspolymer-2, Polyacrylate Crosspolymer-6, Vigna Aconitifolia Seed Extract, Tocopheryl Acetate, Tocopherol, Citric Acid, Xanthan Gum, Maltodextrin, Melatonin, Retinal, Silica, Disodium EDTA, Phospholipids, Synthetic Fluorphlogopite, CI 77891, Ascorbic Acid, T-Butyl Alcohol, Rosmarinus Officinalis Leaf Extract, Palmitoyl Tetrapeptide-7, Tin Oxide, Chrysin
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterPropanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.
Propanediol is not likely to cause sensitivity and considered safe to use.
It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolRetinal is a form of retinoid. Retinoids are the gold-standard class of anti-aging ingredients.
Retinal has many benefits as other retinoids: improve skin texture, reduce large pores, reduce the effects of aging, reduce the visibility of dark spots, heal scars, and fight acne.
Studies show retinal may work at a faster rate than retinol due to its structure.
All retinoids have to be converted into retinoic acid before starting to work. Some retinoids take several steps of conversion before binding. Retinal is only one step away, making it more potent.
Like other retinoids, retinal may be irritating. It is best to ease into using this ingredient frequently.
Using the 'ramp up' method, start by using retinol once a week. This gives your skin time to adjust and decrease irritation. Once you feel ready, you can slowly increase the frequency of retinol use.
Using retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
Learn more about RetinalBakuchiol is a plant-derived antioxidant (it's vegan!). It is often called the replacement for retinol although it is not part of the same family.
It has similar effects as retinol: skin smoothing, reducing discoloration, and preventing wrinkles. It does not cause as much irritation as traditional retinoids.
Bakuchiol works by breaking down free radicals and stimulating collagen production in skin.
Combining bakuchiol with retinol will not have adverse side effects. Studies show using them will just boost the benefits. Bakuchiol is also found to help stabilize retinol.
While bakuchiol does not make the skin more sun sensitive, we recommend wearing SPF on a daily basis.
Read more about traditional retinol
Learn more about BakuchiolDimethicone/Vinyl Dimethicone Crosspolymer is a silicone used to improve the texture of products and absorb oil. It does not get absorbed into the skin.
Like other silicones, Dimethicone/Vinyl Dimethicone Crosspolymer helps condition the skin by creating a barrier. In this sense, it can act as an emollient and trap moisture in.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumDimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.
Dimethicone has been found increase absorption in skin, boosting the benefits of other ingredients. While there is concern for the safety of dimethicone, the levels used in skincare are safe for use.
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateDisodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTATocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolSilica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.
Silica is often used for absorption and can help reduce shine when products are applied. Silica occurs in naturally in materials like clay and sandstone, and it can also be produced synthetically.
Silica is present naturally within the skin during collagen production and when reducing inflammation.
Learn more about SilicaCaprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
Within a product, Caprylic Triglyceride can thicken the product and make spreadability easier by dissolving clumping compounds. An added benefit of Caprylic Triglyceride is its antioxidant properties.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid. Caprylic Triglyceride has not been found to be toxic for human use in concentrations under 50%.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.
Learn more about Caprylic/Capric TriglycerideGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinCitric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.
If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.
Read more about some other popular AHA's here:
Learn more about Citric AcidCaprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
In the US, the alternative name for parfum is 'fragrance'.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumIngredient Ratings
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