Versus

Oxecure Acne Defense Prebio Serum Versus SKIN1004 Madagascar Centella Probio-Cica Intensive Ampoule

Serum
Ampoule
Thai Brand Thailand
Korean Brand South Korea

Updated on January 15, 2025

Overview

What they are

These products are both reef safe . They have a total of 9 ingredients in common

Cool Features

They both contain ceramides and hyaluronic acid

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any common allergens, parabens, silicones or sulfates

What's Inside

They both contain oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Benefits

Concerns

Ingredients Side-by-side

found in both products
Acne Defense Prebio Serum

Water

Skin Conditioning

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Propanediol

Solvent

Sclerotium Gum

Emulsion Stabilising

Ceramide AP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

1,2-Hexanediol

Skin Conditioning

Caprylhydroxamic Acid

Croton Lechleri Resin Extract

Skin Conditioning

Aloe Barbadensis Leaf Juice

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon

Mannitol

Humectant

Cellulose

Absorbent

Hydroxypropyl Methylcellulose

Emulsion Stabilising

Inulin

Skin Conditioning

Yeast Beta-Glucan

Skin Conditioning

Undaria Pinnatifida Extract

Skin Conditioning

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

PEG-40 Hydrogenated Castor Oil

Emulsifying
Oil IconNot safe for Fungal Acne Icon

Melaleuca Alternifolia Leaf Oil

Antioxidant
Antioxidant IconFragrance IconOil IconGood for Oily Skin IconMay worsen Eczema Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Dipotassium Glycyrrhizate

Humectant
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Lactobacillus/Rye Flour Ferment

Skin Conditioning

Saccharide Isomerate

Humectant

Xanthan Gum

Emulsifying

Glucose

Humectant

Chondrus Crispus Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Hydroxypropyltrimonium Hyaluronate

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Sodium Acetylated Hyaluronate

Humectant
Hyaluronic Acid Icon

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Sodium Hyaluronate Crosspolymer

Humectant
Hyaluronic Acid Icon

Hydrolyzed Sodium Hyaluronate

Skin Conditioning

Potassium Hyaluronate

Skin Conditioning

Caprylyl Glycol

Emollient

Houttuynia Cordata Extract

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Glycyrrhiza Glabra Root Extract

Bleaching
Good for Dark Spots Icon

Scutellaria Baicalensis Root Extract

Astringent

Pistacia Lentiscus Gum

Masking

Lecithin

Emollient

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Alcohol

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon

Morus Alba Root Extract

Bleaching

Artemisia Capillaris Flower Extract

Skin Conditioning

Ziziphus Jujuba Fruit Extract

Skin Conditioning

Taraktogenos Kurzii Seed Oil

Skin Conditioning
1 / 0 Oil Icon

Nigella Sativa Seed Oil

Emollient
Fragrance IconOil Icon

Leptospermum Scoparium Branch/Leaf Oil

Tonic
Oil Icon

Potassium Lauroyl Wheat Amino Acids

Cleansing

Palm Glycerides

Emollient
Not safe for Fungal Acne Icon

Capryloyl Glycine

Cleansing

Magnolia Grandiflora Bark Extract

Antimicrobial
Antioxidant Icon

Centella Asiatica Extract

Cleansing
Helps reduce Skin Redness IconHelps reduce irritation Icon

Polygonum Cuspidatum Root Extract

Antioxidant
Antioxidant Icon

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Chamomilla Recutita Flower Extract

Masking
Helps reduce Skin Redness IconHelps reduce irritation Icon

Rosmarinus Officinalis Leaf Extract

Antimicrobial

Phenoxyethanol

Preservative
Preservative Icon

Sodium Benzoate

Masking
Preservative Icon

Potassium Sorbate

Preservative
Preservative Icon

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Sodium Citrate

Buffering
Madagascar Centella Probio-Cica Intensive Ampoule

Centella Asiatica Extract

Cleansing
Helps reduce Skin Redness IconHelps reduce irritation Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Water

Skin Conditioning

Propanediol

Solvent

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.
  • It has mild preservative properties.

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum
Humectant

Glucose is a simple sugar and is the most important source of energy in all organisms.

In skincare, glucose is used to hydrate the skin. It also acts as a prebiotic for our natural biome.

Glucose is hydrating due to its humectant property. As a humectant, glucose draws moisture from the air and from deeper levels in the skin.

Our skin contains many sugars that act as prebiotics and help strengthen our natural microbiome. Having a healthy microbiome helps protect our skin from harmful bacteria and other contaminants.

Studies show glucose may help with fading discoloration and pigmentation. This is because our skin metabolizes glucose into lactic acid. Lactic acid is an AHA that helps exfoliate the top layer of skin.

Learn more about Glucose
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Cleansing, Skin Conditioning, Smoothing

Centella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.

Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.

Studies show the compounds in centella help with:

The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.

Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.

Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Learn more about Centella Asiatica Extract

When to use

34 Routines
41% use in am
59% use in pm
85% use every day
When to use See routines that use it ->
928 Routines
37% use in am
63% use in pm
90% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Oxecure Acne Defense Prebio Serum 60 ingredients

Acne Defense Prebio Serum hasn't been rated yet.
Rate it now

SKIN1004 Madagascar Centella Probio-Cica Intensive Ampoule 44 ingredients

4.2 /5
from 17 ratings
Works Well (13) Hydrating (11) Great Value (9)
Cheeks's avatar

Cheeks

4 months ago
Review

This has been my favourite barrier supporting ampoule/serum to date! My skin soaks this up I use this both am and pm (with a little more in the pm). I have dry, sensitive and rosacea prone skin and this hasn’t ever aggravated anything, no reactions, blends effortlessly and just gives me a hydrated glowy look! Love it! It’s a creamy ampoule but not super thick and just melts into the skin. It’s so Show more

#great value
#hydrating
#light
#absorbs well
m.evstigneev's avatar

M. Evstigneev

4 months ago
Review

Lovely texture and a good value. Unfortunately, my skin reacted violently to it, it was very irritating, especially around my cheekbones. It is ironic because it’s marketed as soothing and calming for sensitive skin, and I’m not even that sensitive. My suspicion is that I can’t tolerate fermented ingredients because it happened with some other fermented products as well.

#great value
#irritating
#light
#no scent