MEDI-PEEL EGF Scaling Moisture Foot Cream

MEDI-PEEL EGF Scaling Moisture Foot Cream

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Overview

What it is

Foot cream with 78 ingredients that contains exfoliants, niacinamide, peptides, propolis and urea

Cool Features

It is cruelty-free and reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

It doesn't contain any harsh alcohols, parabens or sulfates

Fun facts

MEDI-PEEL is from South Korea. This product is used in 4 routines created by our community.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

What's inside

Ingredients List

47
18
13

Water

Skin Conditioning

Hydrogenated Polydecene

Emollient

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconGood for Barrier Repair Icon

Urea

Buffering
Urea IconHelps hydrate Dry Skin IconGood for Skin Texture IconGood for Barrier Repair Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin IconGood for Barrier Repair Icon

Honey Extract

Humectant
Helps hydrate Dry Skin Icon

Propolis Extract

Skin Conditioning
Propolis IconHelps fight Acne IconHelps reduce irritation IconHelps reduce Skin Redness IconGood for Scar Healing Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconCoconut Derived IconBad for Acne Prone Skin IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon

Niacinamide

Smoothing
Niacinamide IconHelps fight Acne IconHelps with Anti-Aging IconHelps brighten skin IconHelps reduce irritation IconGood for Oily Skin IconGood for Minimizing Pores IconHelps reduce Skin Redness IconGood for Scar Healing IconGood for Dark Spots IconGood for Skin Texture IconGood for Barrier Repair Icon

PEG-100 Stearate

Surfactant
0 / 0 Not safe for Fungal Acne Icon

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Chamomilla Recutita Flower Extract

Masking
Helps reduce irritation IconHelps reduce Skin Redness IconGood for Barrier Repair Icon

Borago Officinalis Extract

Emollient
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Jasminum Officinale Extract

Masking
May cause irritation IconEU Allergen Icon

Lavandula Angustifolia Extract

Skin Conditioning
May cause irritation IconEU Allergen Icon

Mentha Arvensis Leaf Extract

Masking

Rosmarinus Officinalis Extract

Antimicrobial

Salvia Officinalis Leaf Extract

Cleansing

Thymus Vulgaris Extract

Perfuming
Fragrance Icon

Hamamelis Virginiana Extract

Antiseborrhoeic
Can worsen Dry Skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Mentha Piperita Leaf Extract

Skin Conditioning

Chamaecyparis Obtusa Leaf Extract

Skin Conditioning

Eucalyptus Globulus Leaf Extract

Perfuming
Fragrance Icon

Pinus Densiflora Leaf Extract

Antimicrobial
Antioxidant Icon

Lactobacillus/Soybean Ferment Extract

Skin Conditioning

Salix Alba Bark Extract

Astringent
Helps reduce irritation IconGood for Oily Skin IconGood for Dark Spots Icon

Cinnamomum Cassia Bark Extract

Masking
May worsen Eczema Icon

Origanum Vulgare Leaf Extract

Skin Conditioning

Scutellaria Baicalensis Root Extract

Astringent
Helps reduce Skin Redness Icon

Portulaca Oleracea Extract

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconHelps reduce Skin Redness Icon

Royal Jelly Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Centella Asiatica Extract

Cleansing
Helps with Anti-Aging IconHelps reduce irritation IconHelps reduce Skin Redness IconGood for Scar Healing IconGood for Skin Texture IconGood for Barrier Repair Icon

Zea Mays Leaf Extract

Skin Conditioning

Lysine

Skin Conditioning

Histidine

Humectant
Helps with Anti-Aging IconHelps hydrate Dry Skin Icon

Arginine

Masking
Helps hydrate Dry Skin IconGood for Scar Healing Icon

Aspartic Acid

Masking
Helps hydrate Dry Skin Icon

Threonine

Helps hydrate Dry Skin Icon

Serine

Masking
Helps hydrate Dry Skin Icon

Glutamic Acid

Humectant
Helps reduce irritation Icon

Proline

Skin Conditioning
Helps hydrate Dry Skin Icon

Glycine

Buffering
Helps hydrate Dry Skin Icon

Alanine

Masking
Helps hydrate Dry Skin Icon

Valine

Masking

Methionine

Skin Conditioning

Isoleucine

Skin Conditioning

Leucine

Skin Conditioning

Tyrosine

Masking

Phenylalanine

Masking
Helps hydrate Dry Skin Icon

Cysteine

Antioxidant
Antioxidant Icon

Hydrolyzed Glycosaminoglycans

Humectant

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Vitis Vinifera Seed Oil

Emollient
2-3 / 0 Oil IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconNot safe for Fungal Acne Icon

Simmondsia Chinensis Seed Oil

Emollient
0-2 / 0 Oil IconHelps hydrate Dry Skin IconGood for Scar Healing IconGood for Barrier Repair IconNot safe for Fungal Acne Icon

Copper Tripeptide-1

Skin Conditioning
Peptide IconHelps with Anti-Aging IconGood for Scar Healing IconGood for Barrier Repair Icon

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps with Anti-Aging Icon

Palmitoyl Pentapeptide-4

Skin Conditioning
Peptide IconHelps with Anti-Aging IconGood for Skin Texture Icon

Myristoyl Pentapeptide-17

Skin Conditioning
Peptide Icon

Sh-Oligopeptide-1

Skin Conditioning
Peptide IconHelps with Anti-Aging IconGood for Scar Healing Icon

Rh-Polypeptide-11

Skin Conditioning
Peptide Icon

Trehalose

Humectant
Helps with Anti-Aging IconHelps hydrate Dry Skin IconGood for Barrier Repair Icon

Squalane

Emollient
1 / 0 Helps with Anti-Aging IconHelps hydrate Dry Skin IconGood for Barrier Repair Icon

Cyclohexasiloxane

Emollient
Silicon Icon

Butyrospermum Parkii Butter

Skin Conditioning
Helps hydrate Dry Skin IconGood for Barrier Repair IconBad for Acne Prone Skin IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon

Capryloyl Salicylic Acid

Exfoliating
Exfoliant IconHelps fight Acne IconGood for Oily Skin IconGood for Minimizing Pores IconGood for Dark Spots Icon

Adenosine

Skin Conditioning
Helps with Anti-Aging IconHelps reduce irritation IconGood for Scar Healing Icon

Hydroxyacetophenone

Antioxidant
Antioxidant IconHelps reduce irritation IconHelps reduce Skin Redness Icon

Caprylyl Glycol

Emollient
Fatty Alcohol Icon

Dipotassium Glycyrrhizate

Humectant
Helps reduce irritation IconHelps reduce Skin Redness Icon

Dipropylene Glycol

Humectant

Microcrystalline Cellulose

Absorbent

Sodium Polyacrylate Starch

Absorbent

Disodium EDTA

Cellulose Gum

Emulsion Stabilising
0 / 0

CI 19140

Cosmetic Colorant

CI 15985

Cosmetic Colorant

Parfum

Masking
Synthetic Fragrance IconFragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Water, Hydrogenated Polydecene, Glycerin, Urea, Glyceryl Stearate, Butylene Glycol, Honey Extract, Propolis Extract, Cetearyl Alcohol, Niacinamide, PEG-100 Stearate, 1,2-Hexanediol, Chamomilla Recutita Flower Extract, Borago Officinalis Extract, Jasminum Officinale Extract, Lavandula Angustifolia Extract, Mentha Arvensis Leaf Extract, Rosmarinus Officinalis Extract, Salvia Officinalis Leaf Extract, Thymus Vulgaris Extract, Hamamelis Virginiana Extract, Mentha Piperita Leaf Extract, Chamaecyparis Obtusa Leaf Extract, Eucalyptus Globulus Leaf Extract, Pinus Densiflora Leaf Extract, Lactobacillus/Soybean Ferment Extract, Salix Alba Bark Extract, Cinnamomum Cassia Bark Extract, Origanum Vulgare Leaf Extract, Scutellaria Baicalensis Root Extract, Portulaca Oleracea Extract, Royal Jelly Extract, Centella Asiatica Extract, Zea Mays Leaf Extract, Lysine, Histidine, Arginine, Aspartic Acid, Threonine, Serine, Glutamic Acid, Proline, Glycine, Alanine, Valine, Methionine, Isoleucine, Leucine, Tyrosine, Phenylalanine, Cysteine, Hydrolyzed Glycosaminoglycans, Helianthus Annuus Seed Oil, Vitis Vinifera Seed Oil, Simmondsia Chinensis Seed Oil, Copper Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Myristoyl Pentapeptide-17, Sh-Oligopeptide-1, Rh-Polypeptide-11, Trehalose, Squalane, Cyclohexasiloxane, Butyrospermum Parkii Butter, Capryloyl Salicylic Acid, Adenosine, Hydroxyacetophenone, Caprylyl Glycol, Dipotassium Glycyrrhizate, Dipropylene Glycol, Microcrystalline Cellulose, Sodium Polyacrylate Starch, Disodium EDTA, Cellulose Gum, CI 19140, CI 15985, Parfum

Key Ingredients

Benefits

Concerns

Ingredients Explained

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Learn more about Water
Emollient, Masking, Skin Conditioning

Hydrogenated Polydecene is a synthetic emollient. It forms a non-occlusive film on the skin's surface to provide a silky feel without being greasy.

In vivo studies in volunteers with atopic and dry skin showed no irritation or intolerance. The volunteers also saw a positive effect in dryness, scaling, and roughness after 28 days of use.

Concentrations up to 100% in guinea pig tests found it to be non-sensitizing and completely safe for use in cosmetics.

Learn more about Hydrogenated Polydecene
Humectant, Skin Conditioning, Skin Protecting

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Buffering, Humectant, Skin Conditioning

Urea is also called carbamide and is the diamide of carbonic acid. In cosmetics, urea is used to hydrate the skin. It also provides exfoliation in higher concentrations.

As a humectant, urea helps draw moisture from the air and from deep within the skin. This helps hydrate your skin. Studies show urea is an effective moisturizer for dry skin conditions. 40% urea is typical in medications for treating eczema and other skin conditions.

Urea has the strongest exfoliation effect in concentrations higher than 10%. It is a keratolytic agent, meaning it breaks down the keratin protein in the top layer of skin. This helps remove dead skin cells and flaking skin.

In medicine, urea has been shown to help increase the potency of other ingredients, such as fungal treatments.

Humans and animals use urea to metabolize nitrogen-containing compounds. Urea is highly soluble in water. Once dissolved, it is neither acidic nor alkaline.

Urea is actually one of the more well-studied and well-supported ingredients out there if you have eczema.

Clinical trials have shown that urea creams in the 5 - 10% range can:

Higher concentrations (20 -30%) can also help with thickened, scaly patches but is also more likely to sting on active flares.

Skip urea if you have rosacea. The AAD (American Academy of Dermatology) lists it alongside alcohol, menthol, and fragrance as a potential irritant for rosacea-prone skin. Urea's keratolytic and penetration-enhancing properties can trigger stinging, burning, and redness.

As always, your skin is unique, so definitely check in with your dermatologist.

Learn more about Urea
Emollient, Emulsifying

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Learn more about Glyceryl Stearate
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Humectant, Skin Conditioning

This ingredient comes from honey made by bees. It is hydrating, antibacterial, anti-aging, and skin soothing.

Honey also contains amino acids, peptides, Vitamins A, C, and E.

The humectant property of honey draws moisture from the air to your skin. This makes it great at helping to hydrate the skin.

Honey may help reduce the signs of aging due to its antioxidant properties. Fun fact: darker honey has more antioxidants than light honey. The antibacterial property of honey may make it effective at helping to treat acne by killing acne-causing bacteria.

Many people wonder if honey extract is vegan. It is technically a byproduct from bees. This is because honey is created from the digestive enzymes in a bee's stomach.

Remember to be kind to bees :) They are important for many ecosystems and are endangered.

Learn more about Honey Extract
Skin Conditioning

Propolis Extract is a natural ingredient derived from propolis (also known as bee glue). Bees make propolis by mixing their saliva and beeswax with resins collected from tree buds and plants.

This ingredient is packed with bioactive compounds like flavonoids, phenolic acids, and amino acids that give it antioxidant and anti-inflammatory properties.

Research shows it can help:

It also pairs nicely with hydrating ingredients like niacinamide and ceramides.

Just so you know, Propolis Extract is recognized as a contact allergen. In patch tests done in the EU, roughly 1-6% of patients react to it. Be sure to steer clear of this ingredient if you have a known allergy to bee products.

Since it is an animal-derived product, this ingredient is not considered vegan. For vegan alternatives, check out Galactomyces Ferment Filtrate or Centella Asiatica Extract.

Learn more about Propolis Extract
Emollient, Emulsifying, Emulsion Stabilising

Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.

Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.

It plays several roles in a formula:

Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.

Multiple assessments have found it to be non-irritating and non-sensitizing to most people.

However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.

Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.

Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.

Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.

This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.

A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.

Learn more about Cetearyl Alcohol
Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide
Surfactant

Peg-100 Stearate is an emollient and emulsifier. As an emollient, it helps keep skin soft by trapping moisture in. On the other hand, emulsifiers help prevent oil and water from separating in a product.

PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.

Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Masking, Skin Conditioning

Chamomilla Recutita Flower Extract comes from the Chamomile flower.

Chamomile is rich in antioxidants and has anti-inflammatory properties. Several compounds found in chamomile help with soothing, such as bisbolol.

Antioxidant components in chamomile make it an effective ingredient to help slow the signs of aging. Antioxidants help fight free-radical molecules, or molecules that may damage your skin.

Essential oils from chamomile have been found to improve wound healing due to its antimicrobial properties.

Ancient Greeks and Egyptians used Chamomile to treat skin redness and dryness. Chamomile has also been used to help treat stomach issues.

Learn more about Chamomilla Recutita Flower Extract
Emollient, Skin Conditioning

Borago Officinalis Extract is often synonymous with Borago Officinalis Seed Oil. It comes from the seeds of the starflower plant. This plant grows primarily in Europe.

This oil does not have a scent. It contains fatty acids such as linolenic acid. These fatty acids help keep skin hydrated.

Borago Officinalis Seed Oil is an antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells.

Learn more about Borago Officinalis Extract
Masking, Moisturising, Skin Conditioning

Jasminum Officinale Extract can cause irritation.

Skin Conditioning

Lavandula Angustifolia Extract comes from the lavender flower. It's also known as English Lavender and is famous for creating purple fields in Provence, France.

This ingredient anti-inflammatory properties due to its prostanoids and histamine content. Lavender also contains flavonoids and phenolic acids (such as ferulic acid), potent antioxidants.

Lavender extract may have a scent. It contains linalool, a known allergen. However, lavender extract contains less linalool than lavender essential oil.

Learn more about Lavandula Angustifolia Extract
Masking, Refreshing

We don't have a description for Mentha Arvensis Leaf Extract yet.

Antimicrobial, Refreshing, Tonic

Rosemary extract has antioxidant, anti-inflammatory, anti-bacterial, and astringent properties.

This ingredient has a natural fragrance due its small component of rosemary oil. The antioxidant properties from its rosmarinic acid, flavone, and phenolic acids.

Cleansing, Skin Conditioning, Tonic

Sage leaf extract is a culinary and medicinal herb with antibacterial, antioxidant, and soothing properties.

This ingredient is made up of 75-90% ursolic acid, a potent antioxidant and anti-inflammatory compound.

Perfuming, Skin Conditioning

This ingredient comes form the common thyme plant. It has skin conditioning and perfuming ingredients.

In-vitro studies show strong antioxidant activity due to the high phenolic content of thyme.

Studies also demonstrate it has antimicrobial activity against acne-related bacteria. A 2017 study found this extract exhibited anti-inflammatory effects.

However, this ingredient does have sensitization potential due to its terpene content. Terpenes are among the most common causes of contact dermatitis.

This is kind of a double-edged sword situation where the same compounds that give it antimicrobial power can also irritate reactive skin.

Learn more about Thymus Vulgaris Extract
Antiseborrhoeic, Astringent, Skin Conditioning

Hamamelis Virginiana Extract comes from the witch hazel plant.

Unless it is specified to be non-alcohol, many types of witch hazel ingredients are distilled in denatured alcohol.

Witch Hazel has astringent, anti-inflammatory, antioxidant, and antibacterial properties.

The tannin content of witch hazel constrict the appearance of pores by drying out proteins. Witch hazel water gets anti-inflammatory and antibacterial properties from its catechin and gallic acid content.

However, witch hazel may be skin-sensitizing due to the tannin and fragrance compounds.

North American Indigenous groups have used witch hazel to help treat inflammation for centuries.

Learn more about Hamamelis Virginiana Extract
Skin Conditioning

Mentha Piperita Leaf Extract is extract from peppermint leaves. It has a "cooling" sensory feel depending on what compounds are found in the extract.

Peppermint leaves contain polyphenols that antioxidant activity. In-vitro studies show anti-inflammatory and antimicrobial activity against some bacteria and fungi.

Evidence for mint as a "treatment" ingredient is limited and depends heavily on the specific extract type and concentration.

In large percentages, peppermint extract may sensitize the skin.

Learn more about Mentha Piperita Leaf Extract

This ingredient comes from the leaves of the Japanese cypress tree that is also called Hinoki. The leaves are rich in flavonoids with quercitrin being one of its key actives.

A 2023 study tested a 70% ethanol extract on UVA-stressed, collagen-producing skin cells. Across multiple antioxidant tests, this extract protected skin from free radicals at meaningful rates.

And the coolest part? At 1000 ”g/mL, it blocked two enzymes (collagenase and elastase) almost as well as vitamin C did at the same dose. Collagenase and elastase are the enzymes that break down your skin's collagen and elastin over time.

The same study found this ingredient lowered skin-breakdown enzymes and inflammation signals while bumping up collagen production in UV-stressed cells.

A 2024 follow-up tested a fermented version (fermented with mushroom) and it calmed down several key inflammation markers in irritated immune cells. So besides anti-aging, this ingredient can also help soothe skin.

Most of the data right now is still at the cell-culture stage rather than from human clinical trials. However, there's no harm in adding this ingredient to your routine.

Just be sure to patch test if you have a history of sensitivity toward botanical extracts.

Learn more about Chamaecyparis Obtusa Leaf Extract
Perfuming, Skin Conditioning

Eucalyptus globulus leaf extract comes from the leaves of the blue gum tree. It has perfuming and skin conditioning properties.

According to a manufacturer, this ingredient has antioxidants to help protect skin against free radicals.

This ingredient is water-soluble.

Learn more about Eucalyptus Globulus Leaf Extract
Antimicrobial, Antioxidant

This ingredient comes from the needles of the pine tree native to Korea and Japan. It's rich in antioxidant compounds like protocatechuic acid and shikimic acid.

Research on human skin fibroblast cells found that the extract inhibited UVB-induced cytotoxicity and suppressed the enzymes that break down collagen and reduce skin elasticity. This extract also inhibited elastase activity which is relevant for maintaining skin firmness over time.

Studies also show that it has antifungal activity against Malassezia furfur. This is the yeast that causes conditions like dandruff, seborrheic dermatitis, and folliculitis (fungal acne). It also displays anti-inflammatory activity.

On top of all this, all tested fractions of the extract demonstrated significant tyrosinase inhibitory activity comparable to ascorbic acid. This suggests it can play a potential role in fading hyperpigmentation.

Learn more about Pinus Densiflora Leaf Extract

This ingredient is created by fermenting soybean extract with the bacteria, lactobacillus.

Some studies have shown it to have antioxidant properties. One study found this ingredient to have stronger properties than non-fermented soybean extract.

Another study found in increase of isoflavones, amino acids, and peptides in fermented soy milk.

Learn more about Lactobacillus/Soybean Ferment Extract
Astringent, Skin Conditioning, Soothing

Salix Alba Bark Extract comes from the bark of the white willow tree. The official CosIng listing states this ingredient to have astringent, skin conditioning, soothing, and tonic properties.

Its star compound is salicin, a natural glucoside that is chemically related to salicylic acid. That's why you'll often see it marketed as a "natural BHA alternative" but that's a bit of a stretch.

Your skin can't convert salicin to salicylic acid because it needs specific enzymes that aren't present on the skin's surface. It won't behave like true salicylic acid, especially at the concentrations used in cosmetics.

However, this ingredient has its own perks. It contains flavonoids, polyphenols, and tannins that give it proven antioxidant and soothing properties.

An 8-week clinical study found a cream with 2% of this extract improved skin microcirculation, elasticity, and dark circles. This is most likely due to its role in increasing hyaluronic acid synthesis in fibroblasts and improved vascular integrity.

Another study found a topical serum with 0.5% salicin showed improvements in visible signs of aging, hyperpigmentation, and texture.

Just be careful if you have a known aspirin/salicylate allergy and be sure to consult with a medical professional about using this ingredient if you do.

Fun fact: Willow Bark extract has been used for thousands of years and ancient civilizations used white willow to help treat pain and fevers.

Learn more about Salix Alba Bark Extract

This ingredient comes from the cinnamon tree native to southern China.

Though cinnamon has a wonderful taste, it can cause skin irritation due to its rich coumarins, cinnamaldehyde, and styrene content.

Skin Conditioning

Oregano leaf is a culinary and medicinal herb with skin conditioning properties.

Astringent, Humectant, Soothing

Scutellaria Baicalensis Root Extract comes from the Baikal skullcap or Chinese skullcap plant. This plant is native to Northeast Asia and can be found in China, Mongolia, Korea, and Siberia.

In cosmetics, Scutellaria Baicalensis Root Extract provides antioxidant and anti-inflammatory benefits. This is due to the flavonoid composition of Scutellaria Baicalensis Root Extract.

In Chinese traditional folk medicine, Scutellaria Baicalensis Root Extract is used to help treat lung issues and hypertension.

Learn more about Scutellaria Baicalensis Root Extract
Skin Conditioning

This extract comes from Purslane, a succulent. It has anti-inflammatory, antioxidant, and hydrating properties.

Purslane is very nutritious. It contains omega-3 fatty acids, NMFs, many vitamins, minerals, and antioxidants. The vitamins found in purslane include: Vitamin C, Vitamin A, and Vitamin E.

Fun fact: Purslane is a succulent with an extensive habitat. It is used in traditional Korean medicine to treat irritated skin.

Nowadays, purslane is becoming a superfood due to its highly nutritious content.

Learn more about Portulaca Oleracea Extract
Skin Conditioning

Royal Jelly Extract comes from a secretion made by worker honeybees. This secretion is white and described as creamy.

This compound has antibacterial, anti-aging, and anti-inflammatory properties.

Studies show Royal Jelly to contain amino acids, fatty acids, and a variety of vitamins, including Vitamin Bs. Many of these components are antioxidants, which help with anti-aging. The fatty acids in Royal Jelly make it a hydrating ingredient.

Several animal studies show Royal Jelly to boost collagen production and reduce inflammation.

The Vitamin Bs found in Royal Jelly include:

Royal Jelly is derived from honeybees. This means it is not vegan.

Learn more about Royal Jelly Extract
Cleansing, Skin Conditioning, Smoothing

Centella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.

Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.

Studies show the compounds in centella help with:

The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.

Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.

Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Learn more about Centella Asiatica Extract
Skin Conditioning

We don't have a description for Zea Mays Leaf Extract yet.

Skin Conditioning

Lysine is an essential amino acid (your body cannot make it on its own). It has skin conditioning properties and one of the key players in collagen synthesis.

When your body creates collagen, lysine is basically the glue that holds everything together. It helps collagen fibers lock into each other and stay strong, with vitamin C being its trusty sidekick. Without enough lysine, this glue gets flimsy and less firm, resulting in less bouncy skin.

In skincare, lysine is mostly there to help keep your skin moisturized. It carries water through your skin's layers so everything stays plump.

So will putting lysine on your face create bouncier skin?

It's hard to say; most of the exciting collagen research on lysine comes from oral supplements or lab studies on mice. Further research is needed to truly understand what role topical lysine plays in skincare and your skin.

However, there's no harm in adding lysine to your routine as a supportive and hydrating ingredient.

Learn more about Lysine
Humectant, Skin Conditioning

Histidine is a semi-essential amino acid used by our bodies to create protein. It has humectant and skin conditioning properties.

Our bodies use histidine to create filaggrin - filaggrin is a structural protein that the skin uses in maintaining skin barrier.

One study found histidine and carnosine to be a dynamic duo for your skin:

Oral histidine has also been found to help with filaggrin-deficit skin disorders such as atopic dermatitis.

Why is it considered a semi-essential amino acid? This is because adults are able to create it but children must get it from their diet.

Learn more about Histidine
Masking, Skin Conditioning

Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.

It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.

A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.

Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.

One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.

Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.

Learn more about Arginine
Masking, Skin Conditioning

Aspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.

Our body uses Aspartic Acid to help build collagen and elastin. It also plays a role in hydrating skin.

Threonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.

Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.

Masking, Skin Conditioning

Serine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.

Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.

Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.

Learn more about Serine
Humectant

Glutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.

In cosmetics, glutamic acid is a famous humectant. It draws water from the air to your skin, keeping your skin hydrated (like hyaluronic acid).

An in-vitro study from 2024 found glutamic acid to play a role in inhibiting inflammation and thus a potential skin-soothing ingredient.

Other studies show it to be have potential wound healing, skin barrier repair, and hair growth properties.

Glutamic acid has poor solubility in water and other solvents.

Learn more about Glutamic Acid
Skin Conditioning

Proline is a non-essential amino acid, meaning your body can make it on its own. In skincare, it is a skin conditioning ingredient that keeps skin soft and hydrated.

It makes up about 23% of the collagen molecule (collagen is the protein responsible for keeping your skin firm) and is involved in your skin's natural hyaluronic acid production. When applied topically, proline can penetrate the skin fairly well due to its small molecular size.

Reviews of this ingredient have found it to be neither a dermal irritant nor a sensitizer.

Fun fact: Proline can be found in protein-rich foods like meat, fish, eggs, and dairy.

Learn more about Proline
Buffering, Skin Conditioning

Glycine is the smallest amino acid and a key building block of collagen. It's part if your skin's Natural Moisturizing Factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

A study from 2022 found that an amino acid complex featuring taurine, arginine, and glycine significantly reduced skin irritation, improved redness, and accelerated the skin repair process.

Masking, Skin Conditioning

Alanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.

Masking, Skin Conditioning

Valine is an essential amino acid. It is used by our bodies for tissue repair and muscle growth.

An essential amino acid is one in which our bodies cannot naturally produce so we must get them through diet. Foods such as eggs, dairy, red meat, and fish contain valine.

This ingredient can either be derived from an animal product or be synthetically created.

Learn more about Valine
Skin Conditioning

Methionine is an essential amino acid. It is a conditioning agent and commonly found in both skin and hair products.

This amino acid is a precursor to glutathione, a powerful antioxidant.

Fun fact: Methionine can be found in meat, fish, and dairy. It cannot be naturally produce and requires dietary intake.

Learn more about Methionine
Skin Conditioning

Isoleucine is an amino acid that helps reinforce our skin barrier. This amino acid plays a role in creating protein for the body.

Fun fact: Isoleucine is found in meat, fish, dairy, legumes, and nuts.

Skin Conditioning

We don't have a description for Leucine yet.

Masking, Skin Conditioning

Tyrosine is one of the amino acids used to create protein. It plays a role in melanin production.

A study from 2012 found tyrosine to show promising results in restoring skin volume.

Masking, Skin Conditioning

Phenylalanine is an amino acid. It is a skin soothing and hydrating ingredient. Amino acids play a crucial role in wound healing and skin hydration.

This ingredient is also used to help even out skin tone due to its ability to disrupt the melanin production process.

Two structures of phenylalanine exist: L-phenylalanine and D-phenylalanine. L-phenylalanine is essential, this means our bodies cannot produce it naturally and we must get it from foods. Our bodies convert D-phenylalanine to neurotransmitters, and D-phenylalanine is found in our bodies naturally.

Some foods that contain L-phenylalanine include eggs, soybeans, beef, milk.

Learn more about Phenylalanine
Antioxidant, Masking

Cysteine is an amino acid found in our bodies. It becomes an antioxidant when converted into gluthatione.

Once it becomes gluthatione, it prevents oxidative damage to parts of our cell. Gluthatione has also been shown to protect our skin from UV-B induced damage.

Humectant, Skin Conditioning

We don't have a description for Hydrolyzed Glycosaminoglycans yet.

Emollient, Masking, Skin Conditioning

Helianthus Annuus Seed Oil is a plant oil derived from the seeds of a sunflower.

It is rich in fatty acids, primarily linoleic acid and oleic acid. This gives it emollient and skin conditioning properties.

The reason this ingredient is so effective is because it forms a thin film on the skin that reduces transepidermal water loss (TEWL) while supplying linoleic acid to the stratum corneum to improve barrier strength.

The high linoleic acid content is particularly noteworthy for acne-prone skin.

Research suggests that acne-prone skin tends to be deficient in linoleic acid in sebum. Topical application may help replenish this to support a healthier follicular environment and less comedone-promoting sebum.

One randomized study found sunflower seed oil preserved skin barrier integrity in adult volunteers with and without atopic dermatitis (outperforming olive oil).

This ingredient is well-studied, gentle, and an effective emollient suitable for most skin types.

On fungal acne: This ingredient may not be Fungal acne (Malassezia folliculitis) safe. This is because it contains fatty acids with carbon chain lengths in the C11-C24 range.

Learn more about Helianthus Annuus Seed Oil
Emollient, Skin Conditioning

Vitis Vinifera Seed Oil comes from the grape vine. Grape seeds are a byproduct of creating grape juice or wine.

The components of grape seeds have many skin benefits. Research has found it to be antimicrobial and anti-inflammatory. It also contains many potent antioxidants such as Vitamin E , Vitamin C, proanthocyanidins, polyphenols, flavonoids, and anthocyanins. Proanthocyanidin has been shown to help even out skin tone.

Antioxidants help fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Antioxidants help stabilize free-radicals by donating extra electrons. Grape seed extract may help reduce the signs of aging.

The antimicrobial properties of grape seed may help treat acne. However, more research is needed to support this claim.

Grape seed has also been found to help absorb UV rays. Grape seed extract should not replace your sunscreen.

The fatty acids of grape seed oil give it emollient properties. Emollients help soothe and soften your skin by creating a film. This film traps moisture within, keeping your skin hydrated.

Learn more about Vitis Vinifera Seed Oil
Emollient, Skin Conditioning

Jojoba oil is one of the most well-studied plant-derived ingredients in cosmetics. It is an emollient with a special structure.

Because it is made up of 97-98% wax esters, it closely mirrors the linear monoesters found in human sebum. This makes it skin compatible, non-greasy, and lightweight.

Unlike other plant oils, jojoba wax doesn't easily penetrate skin. It mostly works in the uppermost layers as an emollient. This just means it forms a light barrier on the skin to help retain moisture.

Formulations with jojoba esters up to 90% reduced transepidermal water loss (TEWL) and increased barrier recovery by 81% (outperforming bisabolol at 47%).

Besides barrier support, the science also suggests jojoba to have anti-inflammatory effects and potential applications for skin infections, aging, and wound healing.

Fun fact: Indigenous cultures have used jojoba as a moisturizer and to help treat burns for centuries.

Fungal acne: The Malassezia yeast is known to metabolize fatty acids in the C11-24 range and jojoba's dominant fatty acid components fall into this range. This ingredient may not be fungal acne safe.

Learn more about Simmondsia Chinensis Seed Oil
Skin Conditioning

Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.

It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.

While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.

Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.

Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.

Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.

For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.

After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.

While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.

Read more about other common types of peptides here:

Learn more about Copper Tripeptide-1
Humectant, Skin Conditioning

Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".

It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.

The comparison to Botox does have limits because the molecule is water-loving and relatively large.

Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.

So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.

A 12 week human study of a multi-ingredient regimen containing this ingredient saw:

While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).

Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.

Learn more about Acetyl Hexapeptide-8
Skin Conditioning

You might know this ingredient as Matrixyl. It is a synthetic peptide made up of five amino acids attached to a palmitic acid, a fatty acid that helps it absorb into skin more easily.

As a signal peptide, Matrixyl acts like a little messenger. Once it reaches your skin cells, it tells them to ramp up production of collagen, elastin, and other proteins that keep skin looking firm and smooth.

A 12 week clinical study found that a moisturizer containing just 3 ppm of Matrixyl led to a significant improvement in fine-lines and wrinkles. Another study showed an 18% reduction in wrinkle depth, 37% reduction in wrinkle thickness, and a 21% improvement in skin firmness after just 28 days of twice-daily use.

The coolest part is that it works at incredibly low concentrations (like 0.0003%) and it plays well with other actives.

The CIR (Cosmetic Ingredient Review) panel found it to be non-sensitizing across multiple tests and human patch tests also showed no irritation or sensitization.

Fun fact: Matrixyl was originally developed by French company Sederma and Procter & Gamble.

Read more about other common types of peptides here:

Learn more about Palmitoyl Pentapeptide-4
Skin Conditioning

Myristoyl Pentapeptide-17 is a five amino peptide attached to myristic acid to help it absorb better into skin. It's mostly used for lash growth and as a delivery vehicle for other ingredients.

The myristic acid "tail" is basically a delivery upgrade that helps the peptide mix with your skin's natural oils so it can get where it needs to go.

In your eyelash follicles, it activates the keratin gene and promotes nutrient absorption into the follicle. This translates to thicker and longer eyelashes over time.

Besides stimulating keratin production for lash growth, this ingredient enhances the delivery of other active ingredients in a formula.

The clinical evidence is still pretty early-stage at this point. A 90 day study in 29 participants found improvements in lash length (10.52%), volume (9.3%), thickness (35%), and curl (50.83%) with no adverse reactions reported.

You might have heard that eyelash serums can cause pigmentation change in eye color to turn eyes brown. This is associated with a different class of lash serum ingredients: prostaglandin analogs.

Myristoyl Pentapeptide-17 is a different thing entirely and has no known association with iris pigmentation changes. The 90 day study noted no adverse effects around the eye area at all.

Learn more about Myristoyl Pentapeptide-17
Skin Conditioning

sh-Oligopeptide-1 is a peptide found naturally in our bodies. Peptides are the building blocks for collagen and elastin in our skin.

In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.

Studies find EGF help with:

In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.

According to Dr. Zoe Draelos, growth factors have some drawbacks:

There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.

Learn more about Sh-Oligopeptide-1
Skin Conditioning

Rh-Polypeptide-11 is a peptide.

Humectant, Moisturising

Trehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.

As a humectant, trehalose helps draw moisture from the air to your skin. This helps keep your skin hydrated.

Due to its antioxidant properties, trehalose may help with signs of aging. Antioxidants help fight free-radical molecules, unstable molecules that may damage your skin.

In medicine, trehalose and hyaluronic acid are used to help treat dry eyes.

Some animals, plants, and bacteria create trehalose as a source of energy to survive freeze or lack of water.

Learn more about Trehalose
Emollient, Skin Conditioning

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Learn more about Squalane
Emollient, Skin Conditioning, Solvent

Cyclohexasiloxane is a type of silicone more commonly known as D6. It is an emollient and solvent.

Cyclohexasiloxane is used to evenly distribute ingredients throughout the product. When applied to the skin, Cyclohexasiloxane evaporates and leaves behind a silky feel.

As an emollient, it can help the skin feel soft and hydrated. It is also used to reduce frizz in hair products.

Learn more about Cyclohexasiloxane
Skin Conditioning

This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.

Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).

In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).

Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.

Shea butter also contains vitamins A and E which may contribute to antioxidant activity.

While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.

This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.

Learn more about Butyrospermum Parkii Butter
Exfoliating, Skin Conditioning

Capryloyl Salicylic Acid comes from salicylic acid, the famous acne-fighting BHA.

It usually goes by a more common name of LHA, or lipohydroxy acid.

Like salicylic acid, this ingredient is a chemical exfoliant that can help break down the oil in your pores and reduce inflammation.

Though studies for LHA do show it to be less effective than salicylic acid. To be fair, salicylic acid is the reigning monarch of acne treatments.

However, a study from 2009 found LHA to be comparable to BPO, making it a good alternative for people with sensitive skin. Another study of 14 patients found a significant decrease in comedones after using LHA.

Another pro of LHA? It is less irritating than salicylic acid due to its large molecule size.

Large molecules cannot penetrate skin as well, so they are gentler on the skin. LHA is much less penetrative than salicylic acid.

An in-vitro study (not done on a living organism) found only 6% of LHA penetrated past the statum corneum compared to 58% of salicylic acid. An in-vivo (done on a living organism) analysis revealed ~17% of LHA was still present in the top layer of skin after 4 days, versus ~9% of salicylic acid.

Interestingly, a study from 2008 found LHA comparable to another famous acid, glycolic acid.

This study found about 10% of LHA is as effective as 20-50% of glycolic acid in treating hyperpigmentation and fine-lines.

Hydroxy acids have been found to stimulate skin protein, lipids, and thermal thickening. This may have anti-aging benefits.

Learn more about Capryloyl Salicylic Acid
Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine
Antioxidant

Hydroxyacetophenone is antioxidant with skin conditioning and soothing properties. It also boosts the efficiency of preservatives.

Though naturally occuring in Norwegian spruce needles, this ingredient is usually synthetically created.

This ingredient is not irritating or sensitizing. Recent research also suggests it may have skin-brightening effects through tyrosinase inhibition.

Learn more about Hydroxyacetophenone
Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Learn more about Caprylyl Glycol
Humectant, Skin Conditioning

Dipotassium Glycyrrhizate comes from licorice root.

Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.

One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.

Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.

Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.

Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.

Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.

Learn more about Dipotassium Glycyrrhizate
Humectant, Masking, Solvent

Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.

This ingredient helps:

Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Learn more about Dipropylene Glycol
Absorbent, Emulsion Stabilising, Stabilising

Microcrystalline Cellulose is another name for refined wood pulp. It is used as an emulsifier and mattifying ingredient. As an emulsifier, it helps keep ingredients together.

Absorbent, Emulsion Stabilising

We don't have a description for Sodium Polyacrylate Starch yet.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Learn more about Disodium EDTA
Emulsion Stabilising, Masking

Cellulose Gum is a water-soluble polymer that comes from cellulose. It is used to change the texture of a product and to help stabilize emulsions.

As an emulsifier, cellulose gum specifically thicken the texture of water-based products.

This ingredient is considered hypoallergenic and non-toxic. Cellulose Gum can be found in cosmetics, food, and other household goods such as paper products.

Learn more about Cellulose Gum
Cosmetic Colorant

CI 19140 is also known as Tartrazine. Tartrazine is a synthetic dye used in cosmetics, foods, and medicine to add a yellow color.

Tartrazine is created from petroleum and is water-soluble.

Some people may experience allergies from this dye, especially asthmatics and those with an aspirin intolerance.

Learn more about CI 19140
Cosmetic Colorant

Ci 15985 is a dye made from petroleum. It is synthetically created and approved by the FDA for use in foods and cosmetics.

The color of this dye is orange/yellow.

This ingredient can be found in makeup, sun care, and skincare.

Learn more about CI 15985
Masking, Perfuming

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Learn more about Parfum

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MEDI-PEEL is a Korean brand

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· Updated September 18, 2024 Added by anemone