Versus

SkinBetter Science Alto Advanced Defense and Repair Serum Versus Alastin C-Radical Defense Antioxidant Serum

Serum
Serum
American Brand United States
American Brand United States

Updated on August 23, 2023

Overview

What they are

These products are both reef safe serums. They have a total of 17 ingredients in common

Cool Features

They both contain Vitamin C and Vitamin E

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, common allergens, parabens, silicones or sulfates

What's Inside

They both contain fragrances

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Alto Advanced Defense and Repair Serum

Water

Skin Conditioning

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Propanediol

Solvent

Ethylhexyl Olivate

Skin Conditioning
Not safe for Fungal Acne Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Chlorogenic Acids

Antioxidant
Antioxidant Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Lauryl Lactate

Emollient

Dimethyl Isosorbide

Solvent

Pyrroloquinoline Quinone Allyl Ester

Antioxidant
Antioxidant Icon

Hydrolyzed Sodium Hyaluronate

Skin Conditioning

Glycyrrhiza Glabra Root Extract

Bleaching
Good for Dark Spots Icon

Tetrahexyldecyl Ascorbate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Ergothioneine

Antioxidant
Antioxidant Icon

Benzylidene Dimethoxydimethylindanone

Skin Protecting

Arabidopsis Thaliana Extract

Antioxidant
Antioxidant Icon

Carnosine

Skin Conditioning

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Vitis Vinifera Seed Extract

Antimicrobial
Antioxidant Icon

Theobroma Cacao Seed Extract

Antioxidant
Antioxidant Icon

Curcuma Longa Root Extract

Masking
Fragrance Icon

Olea Europaea Fruit Extract

Bleaching

Euterpe Oleracea Fruit Extract

Trifluoroacetyl Tripeptide-2

Skin Conditioning
Peptide Icon

Buddleja Officinalis Flower Extract

UV Filter

Coffea Arabica Leaf Cell Extract

Antioxidant
Antioxidant Icon

Crocus Sativus Leaf Cell Culture Extract

Skin Protecting

Superoxide Dismutase

Antioxidant
Antioxidant IconHelps with Anti-Aging Icon

Ubiquinone

Antioxidant
Antioxidant IconHelps with Anti-Aging IconGood for Dark Spots Icon

Plankton Extract

Skin Conditioning

Micrococcus Lysate

Skin Conditioning

Arginine

Masking
Good for Scar Healing IconNot safe for Fungal Acne Icon

Zingiber Officinale Root Extract

Masking

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide AP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide EOP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Linoleic Acid

Cleansing
Helps hydrate Dry Skin IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Linolenic Acid

Cleansing
Fragrance IconNot safe for Fungal Acne Icon

Sea Whip Extract

Skin Conditioning

Bisabolol

Masking
Helps reduce irritation Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Phytosphingosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Jojoba Esters

Emollient
Not safe for Fungal Acne Icon

Sodium PCA

Humectant
0 / 0

Pentylene Glycol

Skin Conditioning

Methyl Gluceth-20

Humectant

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Helianthus Annuus Seed Wax

Skin Conditioning
Not safe for Fungal Acne Icon

Acacia Decurrens Flower Wax

Emollient
Not safe for Fungal Acne Icon

Lecithin

Emollient

Sodium Lauroyl Lactylate

Emulsifying

Dicetyl Phosphate

Emulsifying

Propanediol Dicaprylate/Caprate

Emollient

Polyglycerin-3

Humectant

Ceteth-20 Phosphate

Cleansing

Diisostearyl Malate

Emollient

Xanthan Gum

Emulsifying

Steareth-2

Emulsifying
2 / 2

Acacia Senegal Gum

Masking

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Antioxidant
Antioxidant Icon

Carbomer

Emulsion Stabilising
1 / 0

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Dextran

Ricinoleth-40

Cleansing

Sodium Hydroxide

Buffering

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Sodium Phytate

Ethylhexylglycerin

Skin Conditioning

Phenoxyethanol

Preservative
Preservative Icon

Water, Butylene Glycol, Propanediol, Ethylhexyl Olivate, Cetearyl Alcohol, Chlorogenic Acids, Niacinamide, Lauryl Lactate, Dimethyl Isosorbide, Pyrroloquinoline Quinone Allyl Ester, Hydrolyzed Sodium Hyaluronate, Glycyrrhiza Glabra Root Extract, Tetrahexyldecyl Ascorbate, Ergothioneine, Benzylidene Dimethoxydimethylindanone, Arabidopsis Thaliana Extract, Carnosine, Camellia Sinensis Leaf Extract, Vitis Vinifera Seed Extract, Theobroma Cacao Seed Extract, Curcuma Longa Root Extract, Olea Europaea Fruit Extract, Euterpe Oleracea Fruit Extract, Trifluoroacetyl Tripeptide-2, Buddleja Officinalis Flower Extract, Coffea Arabica Leaf Cell Extract, Crocus Sativus Leaf Cell Culture Extract, Superoxide Dismutase, Ubiquinone, Plankton Extract, Micrococcus Lysate, Arginine, Zingiber Officinale Root Extract, Ceramide NP, Ceramide AP, Ceramide EOP, Linoleic Acid, Linolenic Acid, Sea Whip Extract, Bisabolol, Tocopherol, Tocopheryl Acetate, Cholesterol, Phytosphingosine, Jojoba Esters, Sodium PCA, Pentylene Glycol, Methyl Gluceth-20, Glycerin, Helianthus Annuus Seed Wax, Acacia Decurrens Flower Wax, Lecithin, Sodium Lauroyl Lactylate, Dicetyl Phosphate, Propanediol Dicaprylate/Caprate, Polyglycerin-3, Ceteth-20 Phosphate, Diisostearyl Malate, Xanthan Gum, Steareth-2, Acacia Senegal Gum, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Dextran, Ricinoleth-40, Sodium Hydroxide, Citric Acid, Sodium Phytate, Ethylhexylglycerin, Phenoxyethanol

C-Radical Defense Antioxidant Serum

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Antioxidant

Ergothioneine is an amino acid found naturally in mushrooms, grains, and meat. It has antioxidant and skin soothing properties.

According to a manufacturer, this amino acid helps with:

  • Maintaining DNA stability and cell reproduction
  • Enhances cellular immunity
  • Skin brightening
  • Anti-aging
  • Skin soothing
Skin Conditioning

Carnosine is a dipeptide made from two amino acids.

This ingredient helps:

Glycation is the process of sugars binding to and damaging proteins. Too much sugar in our skin can lead to damaged collagen, contributing to factors of aging.

Carnosine is water-soluble and is not able to travel deeper layers of skin. This leads to some doubt about whether it can boost collagen in skin, since collagen is located in the deeper layers of skin.

Fun fact: Carnosine can be naturally found in our muscles and brain.

Learn more about Carnosine
Antimicrobial, Antioxidant, Astringent

Camellia Sinensis Leaf Extract is derived from the leaves of the tea plant. Black tea, green tea, and oolong tea are all harvested from this plant.

This ingredient has many skin benefits:

This ingredient contains polyphenols, a strong antioxidant. Antioxidants help fight off molecules that damage skin cells.

On top of that, the antioxidants in green tea neutralize free-radicals from the sun. This gives the skin some extra UV protection, but should not replace sunscreen.

Many components of tea have anti-inflammatory properties.

Polyphenols and L-theanine help soothe the skin and reduce irritation. The caffeine in Camellia Sinensis Leaf Extract helps calm inflamed blood vessels.

Other compounds found in tea include: Vitamin Bs, linoleic acid, magnesium, calcium, iron, and zinc.

Research has shown both drinking Camellia Sinensis Leaf Tea and applying it to the skin can help boost skin elasticity and hydration. Studies also show using tea extract may reduce sebum, or oil, production.

Learn more about Camellia Sinensis Leaf Extract
Antioxidant, Skin Conditioning

Ubiquinone (Coenzyme Q10) is a molecule already found in our bodies. It is a potent antioxidant and skin-soothing ingredient.

Aging and environmental exposure diminishes our skin's natural ubiquinone levels. This is much like our natural collagen and elastin.

The good news is: studies show applying this ingredient topically replenishes ubiquinone levels in our skin. This also comes with a ton of skin benefits. These benefits include:

Ubiquinone is considered a large molecule and cannot be absorbed into the lower layers of skin. This is why it is believed to be such an effective antioxidant: it protects our skin in the upper layers and prevents damage in the deeper layers.

When used in sunscreen, ubiquinone is shown to increase ingredient stability, increase SPF factor, and add to infrared protection.

Fun fact: ubiquinone is fat-soluble.

Learn more about Ubiquinone
Masking, Skin Conditioning, Tonic

Zingiber Officinale is more commonly known as ginger.

Ginger root has antioxidant, anti-inflammation, and antimicrobial properties.

The antioxidant properties help protect your body from free-radicals. Free-radicals are molecules that may damage your skin cells. As a result, ginger may help slow down signs of aging such as hyperpigmentation and wrinkles.

Studies show ginger inhibits the enzyme that breaks down collagen. It also helps with:

This ingredient has no negative side-effects and is safe to use unless one has a specific allergy to it.

Ginger originates from Southeast Asia but has spread throughout the world. It is now a common spice used in many cultures.

Learn more about Zingiber Officinale Root Extract
Masking, Skin Conditioning, Soothing

Bisabolol is famous for its skin soothing properties. It does this by blocking inflammatory signals, helping to reduce your body's reaction to irritation.

This ingredient also interferes with the process of hyperpigmentation. This can help with reducing dark spots and uneven tone.

Bisabolol is an antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells. By fighting these free-radicals, Bisabolol may slow down signs of aging.

Studies have shown Bisabolol to have antimicrobial properties and may be a fungicide. These properties help preserve a product's shelf life.

All these properties makes bisabolol a great skin barrier helper ingredient.

Bisabolol also helps the absorption of other ingredients.

Note: Synthetic Bisabolol has been shown to be less effective.

Learn more about Bisabolol
Antioxidant, Masking, Skin Conditioning

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol
Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.

This ingredient has emollient and emulsifying properties.

As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.

As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.

This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.

Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.

We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.

Learn more about Lecithin

Sodium Lauroyl Lactylate is the lauric acid sodium salt of lactyl lactate.

Sodium Lauroyl Lactylate is an emulsifier and surfactant.

Emulsifiers help stabilize a product. They do this by preventing ingredients from separating, such as oils and water which do not mix naturally. Surfactants reduce surface tension, making it easier to rinse pollutants off skin.

Due to its relation to lauric acid, it may provide antimicrobial benefits.

Learn more about Sodium Lauroyl Lactylate
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum
Buffering, Masking

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.

If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.

Read more about some other popular AHA's here:

Learn more about Citric Acid
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

When to use

129 Routines
75% use in am
25% use in pm
98% use every day
When to use See routines that use it ->
20 Routines
75% use in am
25% use in pm
100% use every day

Reviews

Here's what our community thinks

SkinBetter Science Alto Advanced Defense and Repair Serum 71 ingredients

2.5 /5
from 2 ratings
Broke Me Out (2) Expensive (2) Doesn't Work (1)
sooyeonkim's avatar

☁️Holly☁️

5 months ago
Review

Expensive. Not as effective as Skinceuticals vitamin c. Has a noticeable yellow tint, despite it using a vitamin c derivative. I don’t know WHY, but I had a gut feeling this broke me out. This is a serum-moisturizer like texture, and I found that it pilled. Kind of a waste of my money :/

#expensive
#broke me out
#pilling
#doesn't work
laurenrollinscampbell's avatar
Review

This makes me break out!

#expensive
#broke me out
#irritating

Alastin C-Radical Defense Antioxidant Serum 43 ingredients

5.0 /5
from 1 rating
Expensive (1) Works Well (1)
sierras1's avatar

Sierra S

3 months ago
Review

I have tried so many vitamin c serums and they all unfortunately broke me out and often stung my overly sensitive skin. I tried everyone's HG, the SkinCeuticals C E Ferulic which was by far the worst. I don't like a lot of Alastin products but this is the only vitamin c I've ever tried that works for me.

#expensive
#works well