Versus

Sisley Paris Supremÿa at Night Supreme Anti-Aging Skin Care Cream Versus SkinBetter Science AlphaRet Overnight Cream

Night Moisturizer
Night Moisturizer
French Brand France
American Brand United States

Overview

What they are

These products are both reef safe night moisturizers. They have a total of 13 ingredients in common

Cool Features

They both contain Vitamin E

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, parabens or sulfates

What's Inside

They both contain fragrances

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Supremÿa at Night Supreme Anti-Aging Skin Care Cream

Water

Skin Conditioning

Butyrospermum Parkii Butter

Skin Conditioning
Helps hydrate Dry Skin IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Methyl Methacrylate Crosspolymer

Prunus Domestica Seed Extract

Emollient

Hydrolyzed Malt Extract

Skin Conditioning

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Lentinus Edodes Extract

Skin Conditioning

Salix Alba Leaf Extract

Skin Conditioning

Adenosine

Skin Conditioning
Good for Minimizing Pores IconGood for Scar Healing Icon

Gossypium Herbaceum Seed Extract

Skin Conditioning

Physalis Alkekengi Calyx Extract

Skin Conditioning

Oryza Sativa Bran Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Padina Pavonica Thallus Extract

Skin Conditioning

Rose Extract

Skin Conditioning

Krameria Triandra Root Extract

Skin Conditioning

Hydrolyzed Vegetable Protein

Skin Conditioning

Oryza Sativa Extract

Absorbent
Helps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing Icon

Rhodochrosite Extract

Antioxidant
Antioxidant Icon

Pelargonium Graveolens Oil

Masking
Fragrance IconOil Icon

Michelia Alba Leaf Oil

Masking
Oil Icon

Rosa Damascena Flower Oil

Masking
Oil Icon

Coriandrum Sativum Fruit Oil

Masking
Fragrance IconOil IconNot safe for Fungal Acne Icon

Simmondsia Chinensis Seed Oil

Emollient
0-2 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Lauryl Glucoside

Cleansing

Polyglyceryl-2 Dipolyhydroxystearate

Skin Conditioning
Not safe for Fungal Acne Icon

Ceteareth-20

Cleansing
2 / 3 May worsen Oily Skin Icon

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Dipropylene Glycol

Masking

Bisabolol

Masking
Helps reduce irritation Icon

Ethylhexylglycerin

Skin Conditioning

Pentylene Glycol

Skin Conditioning

Disodium EDTA

Sodium Hydroxide

Buffering

Xanthan Gum

Emulsifying

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Phenoxyethanol

Preservative
Preservative Icon

Sorbic Acid

Preservative
Preservative Icon

Sodium Benzoate

Masking
Preservative Icon

Potassium Sorbate

Preservative
Preservative Icon

BHT

Antioxidant
Antioxidant Icon

Linalool

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Citronellol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Geraniol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Citral

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Rosacea Icon

Eugenol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Limonene

Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon
AlphaRet Overnight Cream

Water

Skin Conditioning

Sodium Glycolate

Buffering

Glycolic Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Cetearyl Olivate

Not safe for Fungal Acne Icon

Pentylene Glycol

Skin Conditioning

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Skin Conditioning

Butyrospermum Parkii Butter is a plant lipid from the fruit of the Shea Tree. It is an effective skin hydrator and emollient.

Emollients help soothe and soften your skin. It does this by creating a protective film on your skin. This barrier helps trap moisture and keeps your skin hydrated. Emollients may be effective at treating dry or itchy skin.

Shea butter is rich in antioxidants. Antioxidants help fight free-radicals, or molecules that may harm the body. It is also full of fatty acids including stearic acid and linoleic acid. These acids help replenish the skin and keep skin moisturized.

While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.

Shea butter may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.

Learn more about Butyrospermum Parkii Butter
Emollient, Skin Conditioning

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan?

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Learn more about Squalane
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.
  • It has mild preservative properties.

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Skin Conditioning

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Learn more about Panthenol
Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Masking, Skin Conditioning, Soothing

Bisabolol is famous for its skin soothing properties. It does this by blocking inflammatory signals, helping to reduce your body's reaction to irritation.

This ingredient also interferes with the process of hyperpigmentation. This can help with reducing dark spots and uneven tone.

Bisabolol is an antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells. By fighting these free-radicals, Bisabolol may slow down signs of aging.

Studies have shown Bisabolol to have antimicrobial properties and may be a fungicide. These properties help preserve a product's shelf life.

All these properties makes bisabolol a great skin barrier helper ingredient.

Bisabolol also helps the absorption of other ingredients.

Note: Synthetic Bisabolol has been shown to be less effective.

Learn more about Bisabolol
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.

This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.

Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.

Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.

Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.

Learn more about Pentylene Glycol

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

When to use

1 Routine
0% use in am
100% use in pm
100% use every day
114 Routines
1% use in am
99% use in pm
84% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Sisley Paris Supremÿa at Night Supreme Anti-Aging Skin Care Cream 52 ingredients

Supremÿa at Night Supreme Anti-Aging Skin Care Cream hasn't been rated yet.
Rate it now

SkinBetter Science AlphaRet Overnight Cream 52 ingredients

3.3 /5
from 3 ratings
Expensive (3) Absorbs Well (2) Light (2)
carr0t's avatar

Caroline Strahan

9 months ago
Review

This is a great - albeit extremely expensive - alternative for people whose skin is too sensitive for tretonoin/retinols or who aren’t able to manage the dryness they can cause.

I’ve been using it for about a month and a half and I truly have noticed a huge difference in my pore size + fine lines. I do like to use a moisturizer afterwards just to be safe, but this could likely work as a Show more

#expensive
#light
#absorbs well
#no scent
beamayo's avatar

Bea Mayo

1 month ago
Review

Truly my holy grail product. It’s certainly pricey but it’s one of two expensive products I have in my routine and it’s worth the investment imo. One fl oz bottle lasts me ~3 months with nightly use. I’ve used this product consistently for 5 months now and have noticed my skin is brighter, more hydrated, and even toned. I was previously using .05% tret and my skin could never really handle it. Show more

#expensive
#light
#absorbs well
#no scent