Versus

Neogen Dermatology V.Biome Infusion Serum Versus Numbuzin No.5 Vitamin Concentrated Serum

Serum
Serum
Korean Brand South Korea
Korean Brand South Korea

Updated on April 08, 2025

Overview

What they are

These products are both reef safe serums. They have a total of 19 ingredients in common

Cool Features

They both contain hyaluronic acid, niacinamide, Vitamin C and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, common allergens, parabens, silicones or sulfates

What's Inside

They both contain fragrances

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Dermatology V.Biome Infusion Serum

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Propanediol

Solvent

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

1,2-Hexanediol

Skin Conditioning

Cetyl Ethylhexanoate

Emollient

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Caprylic/Capric Triglyceride

Masking

Malva Sylvestris Flower Extract

Skin Conditioning

Cetearyl Olivate

Not safe for Fungal Acne Icon

Glycereth-26

Humectant
0 / 0

Sorbitan Olivate

Emulsifying
Not safe for Fungal Acne Icon

Hydrogenated Lecithin

Emulsifying

Arginine

Masking
Good for Scar Healing IconNot safe for Fungal Acne Icon

Ethylhexylglycerin

Skin Conditioning

Betaine

Humectant
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots Icon

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Anthemis Nobilis Flower Oil

Masking
Fragrance IconOil Icon

Adenosine

Skin Conditioning
Good for Minimizing Pores IconGood for Scar Healing Icon

Carbomer

Emulsion Stabilising
1 / 0

Thuja Occidentalis Leaf Oil

Masking
Fragrance IconOil Icon

Disodium EDTA

Lactococcus Ferment Lysate

Skin Conditioning

Ascorbic Acid

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon

Ferulic Acid

Antimicrobial
Antioxidant IconHelps with Anti-Aging IconGood for Dark Spots Icon

Citrus Aurantium Amara Flower Extract

Refreshing

Collagen Extract

Skin Conditioning
Helps with Anti-Aging Icon

Xanthan Gum

Emulsifying

Maltodextrin

Absorbent

Riboflavin

Cosmetic Colorant

Thiamine Hcl

Masking

Biotin

Antiseborrhoeic

Tranexamic Acid

Astringent
Good for Dark Spots IconGood for Scar Healing Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Lepidium Meyenii Root Extract

Skin Conditioning

Caprylyl Glycol

Emollient

Saccharide Hydrolysate

Humectant

Cyanocobalamin

Skin Conditioning

Sodium Starch Octenylsuccinate

Absorbent

Calcium Pantothenate

Olea Europaea Fruit Oil

Masking
0-2 / 0 Fragrance IconOil IconNot safe for Fungal Acne Icon

Lactobacillus Ferment Lysate

Skin Conditioning
Not safe for Fungal Acne Icon

Sodium Ascorbyl Phosphate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Polyglyceryl-10 Diisostearate

Emulsifying
Not safe for Fungal Acne Icon

Glucose

Humectant

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Pyridoxine Hcl

Skin Conditioning

Hydroxydecyl Ubiquinone

Antioxidant
Antioxidant Icon

Chondrus Crispus Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Menadione

Masking

Resveratrol

Antioxidant
Antioxidant IconHelps reduce irritation IconHelps with Anti-Aging IconGood for Dark Spots Icon

Vitis Vinifera Juice Extract

Antioxidant
Antioxidant Icon

Hydroxypropyltrimonium Hyaluronate

Silica

Abrasive
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon

Malpighia Emarginata Fruit Extract

Skin Conditioning

Citrus Unshiu Peel Extract

Masking

Citrus Aurantifolia Fruit Extract

Skin Conditioning

Citrus Limon Fruit Extract

Masking
May cause irritation Icon

Brassica Oleracea Italica Extract

Astringent

Hippophae Rhamnoides Extract

Masking

Citrus Aurantium Dulcis Fruit Extract

Masking

Citrus Paradisi Fruit Extract

Skin Conditioning

Pentylene Glycol

Skin Conditioning

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Sodium Acetylated Hyaluronate

Humectant
Hyaluronic Acid Icon

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Sodium Hyaluronate Crosspolymer

Humectant
Hyaluronic Acid Icon

Hydrolyzed Sodium Hyaluronate

Skin Conditioning

Potassium Hyaluronate

Skin Conditioning

Dextrin

Absorbent

CI 77220

Cosmetic Colorant

Hydroxypropyl Methylcellulose

Emulsion Stabilising

Water, Glycerin, Propanediol, Niacinamide, Panthenol, 1,2-Hexanediol, Cetyl Ethylhexanoate, Tocopheryl Acetate, Caprylic/Capric Triglyceride, Malva Sylvestris Flower Extract, Cetearyl Olivate, Glycereth-26, Sorbitan Olivate, Hydrogenated Lecithin, Arginine, Ethylhexylglycerin, Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Anthemis Nobilis Flower Oil, Adenosine, Carbomer, Thuja Occidentalis Leaf Oil, Disodium EDTA, Lactococcus Ferment Lysate, Ascorbic Acid, Ferulic Acid, Citrus Aurantium Amara Flower Extract, Collagen Extract, Xanthan Gum, Maltodextrin, Riboflavin, Thiamine Hcl, Biotin, Tranexamic Acid, Squalane, Butylene Glycol, Lepidium Meyenii Root Extract, Caprylyl Glycol, Saccharide Hydrolysate, Cyanocobalamin, Sodium Starch Octenylsuccinate, Calcium Pantothenate, Olea Europaea Fruit Oil, Lactobacillus Ferment Lysate, Sodium Ascorbyl Phosphate, Polyglyceryl-10 Diisostearate, Glucose, Sodium Hyaluronate, Pyridoxine Hcl, Hydroxydecyl Ubiquinone, Chondrus Crispus Extract, Menadione, Resveratrol, Vitis Vinifera Juice Extract, Hydroxypropyltrimonium Hyaluronate, Silica, Malpighia Emarginata Fruit Extract, Citrus Unshiu Peel Extract, Citrus Aurantifolia Fruit Extract, Citrus Limon Fruit Extract, Brassica Oleracea Italica Extract, Hippophae Rhamnoides Extract, Citrus Aurantium Dulcis Fruit Extract, Citrus Paradisi Fruit Extract, Pentylene Glycol, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Dextrin, CI 77220, Hydroxypropyl Methylcellulose

No.5 Vitamin Concentrated Serum

Water

Skin Conditioning

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Tranexamic Acid

Astringent
Good for Dark Spots IconGood for Scar Healing Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Smoothing

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
Skin Conditioning

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Learn more about Panthenol
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride
Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.

This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine
Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Antioxidant, Buffering, Masking

Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.

Not only is vitamin C great for your overall health and immune system, it also has plenty of benefits on your skin.

Vitamin C is best used for brightening skin. It improves dark spots, acne scars, and hyperpigmentation. This is because it blocks the process of skin darkening when exposed to UV.

Remember: Vitamin C should not replace sunscreen!

Your skin uses vitamin C to build collagen. Collagen is one key component in having a strong skin barrier and plump skin. Vitamin C also plays a role in regulating collagen, thus making it effective in improving wrinkles and fine lines.

Ascorbic acid shows potent antioxidant activity. As an antioxidant, it helps fight free-radicals. Free-radicals are molecules that may damage your skin cells. These antioxidants also protect skin against UV damage.

The best formulations include Vitamin E and/or ferulic acid. These two ingredients help stabilize and provide a boost in the benefits of ascorbic acid. This is because ascorbic acid becomes unstable when exposed to UV and air. In fact, you can tell your ascorbic acid has oxidized when it turns an orange-yellow color.

Ascorbic acid is generally compatible with other ingredients. However, using ascorbic acid with other active ingredients might cause irritation. Two ingredients: copper ions and benzoyl peroxide, will inactivate ascorbic acid completely.

Read more about other types of Vitamin C:

Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.

Learn more about Ascorbic Acid
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum
Astringent, Skin Conditioning

Tranexamic Acid is best used for treating hyperpigmentation, discoloration, and melasma. It can also help build a stronger skin barrier.

Once applied, Tranexamic Acid starts decreasing inflammation from UV exposure. Tranexamic Acid also prevents our skin cells from meeting the pigment production cells.

Its brightening property makes it great at reducing the appearance of acne scars and marks.

Fun fact: Tranexamic Acid is also a medication used to reduce heavy bleeding.

This acid is derived from lysine, an amino acid.

Learn more about Tranexamic Acid
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.
  • It has mild preservative properties.

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Skin Conditioning

Chondrus Crispus Extract comes from a red algae native to the northern Atlantic coasts of Europe and North America. It helps hydrate the skin and is rich in antioxidants.

The antioxidants in chondrus crispus include lutein and zeaxanthin. Lutein has the ability to filter blue light from screens.

Other contents of chondrus crispus include polysaccharides, peptides, and amino acids. These help hydrate the skin.

What's the difference between algae and seaweed? Algae is a broad term that includes seaweed. Not all algae is seaweed.

Learn more about Chondrus Crispus Extract
Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.

This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.

Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.

Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.

Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.

Learn more about Pentylene Glycol

When to use

4 Routines
75% use in am
25% use in pm
100% use every day
911 Routines
66% use in am
34% use in pm
88% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Neogen Dermatology V.Biome Infusion Serum 74 ingredients

Dermatology V.Biome Infusion Serum hasn't been rated yet.
Rate it now

Numbuzin No.5 Vitamin Concentrated Serum 47 ingredients

3.4 /5
from 31 ratings
No Scent (14) Hydrating (12) Absorbs Well (11)
ThomasvV's avatar

Thomas VV

4 months ago
Review

This serum is one of the best all-round anti-oxidant and dark spot serums containing:
- vitamin c
- Glutathion!!
- 5% niacinamide
- Q10
- Alpha Arbutin
(Unfortunately they removed TXA)

Skin type: combi acne prone

This is not just a dark spot serum, its a perfect anti-oxidant serum in the morning. Glutathion is a killer ingredient and the concentration of Vit C is low.

My acne Show more

#great value
#hydrating
#absorbs well
#no scent
Cheeks's avatar

Cheeks

7 months ago
Review

This is an okay serum for brightening. I have dry, eczema and rosacea skin and didn’t have any issues with breakouts or irritation BUT I didn’t see any big improvement either and used for about 3 months. I found that it left a slightly tacky feeling no matter how long I left between steps in my routine. No smells or fragrances so that was also a plus.

#great value
#sticky
#no scent
#doesn't work