Mediheal Madecassoside Moisture Blemish Repair Sun Serum SPF 50+ Versus Tocobo Cica Calming Sun Serum SPF 50+
Updated on May 19, 2025
Overview
What they are
These products are both sunscreens. They have a total of 26 ingredients in common
Cool Features
They both contain hyaluronic acid, niacinamide, SPF and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots
Free From
They both do not contain any harsh alcohols, parabens or sulfates
What's Inside
They both contain fragrances and silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Mediheal Madecassoside Moisture Blemish Repair Sun Serum SPF 50+ 64 ingredients
Tocobo Cica Calming Sun Serum SPF 50+ 51 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
Mediheal Madecassoside Moisture Blemish Repair Sun Serum SPF 50+ 64 ingredients
Tocobo Cica Calming Sun Serum SPF 50+ 51 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterDibutyl Adipate is an emollient and solvent. It is created from butyl alcohol and adipic acid.
As a solvent, Dibutyl Adipate helps mix and disperse ingredients evenly.
Dibutyl Adipate is soluble in water and organic solvents. It does not absorb UV rays.
Learn more about Dibutyl AdipateButyloctyl Salicylate is similar to octisalate. It a photostabilizer, SPF booster, emollient and solvent. Its main purpose is to evenly spread out ingredients.
This ingredient is a common sunscreen ingredient carrier and photostabilizer. According to a manufacturer, it is suitable for carrying micro Titanium Dioxide, Zinc Oxide, and pigments.
Photostabilizers help stabilize UV-filters and prevents them from degrading quickly.
Due to regulation loopholes, this ingredient is not required to be labeled as an active chemical filter like other UV ingredients. This is why you'll likely find this ingredient in mineral sunscreens from the US.
According to EU regulation, this ingredient can cause harmful effects to aquatic life.
Learn more about Butyloctyl SalicylateEthylhexyl Triazone is a modern chemical sunscreen that protects from UV-B radiation.
It is the most effective of existing UV-B filters, as it provides the highest level of photo-stable absorption. It protects from the entire UV-B range (280 to 320nm), with it's highest level of protection at 314nm.
Ethylhexyl Triazone is oil soluble, oderless and colorless, which mean it is able to be incorporated into a variety of different formulations.
It is not currently available within the United States due to slow changing FDA regulations. Outside of the US, it is used in formulations at concentrations up to 5%.
Learn more about Ethylhexyl TriazoneYou might know this ingredient as Tinosorb S or Bemotrizinol. It is a UV filter that covers both UVA and UVB rays.
This ingredient has two peak UV absorption peaks ( 310 and 340 nm) and is able to absorb both UV-A and UV-B rays. This ingredient works by preventing UV rays from reaching and damaging your skin.
On top of that - it is highly photostable and helps prevent the photodegration of other sunscreen ingredients such as avobenzone.
Tinosorb S is allowed in the EU, Australia, and Asia. It is close to being approved by the FDA and we'll hopefully get this ingredient in the U.S. by late 2025.
Fun fact: Tinosorb S is the most effective UV absorber at maximum concentration (measured by SPF) permitted in the EU.
This ingredient is oil-soluble, so your oil-cleansers will take this right off at night.
Learn more about Bis-Ethylhexyloxyphenol Methoxyphenyl TriazineNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideEcamsule is a UV-A absorber (290–400 nm) patented by L'Oreal. It is derived from benzylidene camphor, making it highly photostable.
Ecamsule is able to prevent UV from reaching the skin. It absorbs UV and releases it as thermal energy.
It does this by:
The pH of ecamsule needs to be neutralized due to it being an acid. Triethanolamine is a pH adjusting ingredient often used with ecamsule.
This sunscreen ingredient is approved for use in the EU, Canada, and Asia. In the US, you will only find this ingredient in select L'Oreal products.
Learn more about Terephthalylidene Dicamphor Sulfonic AcidPolymethylsilsesquioxane is a silicone used as a film forming agent.
When applied to the skin, this ingredient creates an invisible film on the surface. This film still allows oxygen to pass through, but prevents moisture from escaping. This can help condition and hydrate the skin. It also leaves a silky feel when applied.
Polymethylsilsesquioxane has not been shown to clog pores. It has been deemed safe to use up to 55%, but most cosmetics use much less.
If you have concerns about using this ingredient, we recommend speaking with a professional.
Learn more about Polymethylsilsesquioxane1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Â
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesÂ
Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolWe don't have a description for Poly C10-30 Alkyl Acrylate yet.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Centella Asiatica Leaf Extract comes from the leaves of an herb plant native to Southeast Asia. Centella Asiatica is rich in antioxidants and amino acids. It can help reduce irritation and soothe the skin.
Many active components found in centella asiatica, such as Madecassic Acid and Asiaticoside, encourage the skin to naturally produce hyaluronic acid. This helps keep our skin hydrated. Many of these components also show antioxidant activity and may help reduce the signs of aging.
Research shows centella asiatica can help increase Type I collagen production by increasing fibroblast production. Fibroblast helps form connective tissue.
The combination of all these properties makes centella asiatica leaf extract effective at soothing the skin.
Other components of centella asiatica leaf extract include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.
Recent studies found madecassoside may help prevent damage from UV rays by preventing UV-induced inflammation. Further research is needed.
This plant has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica Leaf ExtractAdenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.
Studies have found adenosine may also help with wound healing.
In skincare products, Adenosine is usually derived from yeast.
Learn more about AdenosineMadecassoside comes from the super popular skin-soothing ingredient, Centella asiatica. It is one of four active compounds found in the extract of Centella Asiatica.
Madecassoside has antioxidant, anti-inflammatory, and hydrating properties. It contains fatty acids, amino acids, beta-carotene, and phytochemicals.
One study found using Madecassoside with ascorbic acid helped reduce the signs of aging and improved skin hydration.
Learn more about MadecassosideSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateCentella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.
Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.
Studies show the compounds in centella help with:
The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.
Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.
Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica ExtractTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolThis ingredient is created by putting sodium hyaluronate through hydrolysis.
You might know this as 'mini' or 'ultra low-molecular weight' hyaluronic acid. The small molecule size means it is able to travel deeper in the skin.
According to studies, low molecular-weight hyaluronic acid can:
One study from 2011 found ultra-low weight HA to show pro-inflammatory properties. Another study from 2022 found it to downregulate UV-B induced inflammation.
Hydrolysis is a process of changing a molecule using water or enzymes.
This ingredient is water-soluble.
Learn more about Hydrolyzed Sodium HyaluronateThis form of hyaluronic acid is produced through fermentation.
According to a manufacturer, it has a positive charge by ionic binding to help moisturize and give hair a smooth feel. This is why you'll find this ingredient in shampoos and body washes.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinMadecassic Acid is a major component of Centella Asiatica Extract. It has anti-inflammatory and antioxidant properties.
It is a triterpenoid, meaning it naturally acts as an antioxidant. Antioxidants protect your skin against damage from environmental factors such as pollution and UV.
Studies show Madecassic Acid helps soothe the skin due to its ability to block inflammation pathways.
Learn more about Madecassic AcidAsiatic Acid is a major component of Centella Asiatica Extract. It has wound-healing, anti-inflammatory, and antioxidant properties.
Studies show Asiatic Acid is able to block the pathway for skin inflammation receptors, helping to soothe skin.
As an antioxidant, asiatic acid helps protect our skin against damaging environmental factors.
Learn more about Asiatic AcidAsiaticoside comes from the super popular skin-soothing ingredient, Centella asiatica. It is one of four active compounds found in the extract of Centella Asiatica.
Asiaticoside is an antioxidant and helps with wound healing. It has been shown to increase antioxidant activity during the wound healing process.
Saccharomyces Ferment Filtrate is created from fermenting Saccharomyces, a yeast also known as baker's yeast or brewer's yeast.
As a humectant, Saccharomyces Ferment Filtrate helps draw moisture from the air to your skin to keep your skin hydrated. The humectant properties comes from its beta-glucan content.
Ingredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Mediheal Madecassoside Moisture Blemish Repair Sun Serum SPF 50+ 64 ingredients
Tocobo Cica Calming Sun Serum SPF 50+ 51 ingredients

Reviews
Here's what our community thinks
Mediheal Madecassoside Moisture Blemish Repair Sun Serum SPF 50+ 64 ingredients
Tocobo Cica Calming Sun Serum SPF 50+ 51 ingredients
I wanted to love this product sooooo bad- I thought it was THE sunscreen after trying SEVERAL through the years. I started using it a couple weeks ago when my skin was looking flawless, it absorbed well, felt hydrating and gave me a nice glow as well as helping with my overall tone. My makeup went on well with it too. However, I think this sunscreen broke me out ðŸ˜. I’ve been trying to gaslight Show more
as someone who struggles with american chemical sunscreen filters but prefers the finish of chemical sunscreens i decided to give this a chance. Unfortunately it broke me out and/or caused an allergic reaction there was small tiny white heads all over my forehead. I’m hoping maybe it was the fragrance but not sure I still want to try to have hope so I will try a fragrance free asian spf and see Show more