Labiotte Skin Enhancer Collagen Tone Up Cream SPF 50+
A face primer with 60 ingredients, including niacinamide, spf, and exfoliants.
Face primer with 60 ingredients that contains exfoliants, hyaluronic acid, niacinamide, SPF and Vitamin E
We independently verify ingredients, backed by peer-reviewed research. Suggest an update.
What's inside
Ingredients List
Water
Skin ConditioningEthylhexyl Methoxycinnamate
UV AbsorberTitanium Dioxide
Cosmetic ColorantGlycerin
HumectantCyclopentasiloxane
EmollientCetyl PEG/PPG-10/1 Dimethicone
Emulsifying4-Methylbenzylidene Camphor
UV AbsorberButyl Methoxydibenzoylmethane
UV AbsorberEthylhexyl Salicylate
UV AbsorberNiacinamide
SmoothingOctocrylene
UV AbsorberPolyglyceryl-3 Polydimethylsiloxyethyl Dimethicone
Skin ConditioningCyclohexasiloxane
EmollientPolyglyceryl-6 Stearate
EmollientSilica
AbrasiveCetyl Ethylhexanoate
EmollientPolyglyceryl-10 Laurate
Skin Conditioning1,2-Hexanediol
Skin ConditioningHydrolyzed Collagen Extract
Skin ProtectingHydrolyzed Hyaluronic Acid
HumectantPortulaca Oleracea Extract
Skin ConditioningAllantoin
Skin ConditioningAdenosine
Skin ConditioningTocopheryl Acetate
AntioxidantPhenoxyethanol
PreservativePanthenol
Skin ConditioningSodium Hydroxide
BufferingButylene Glycol
HumectantEthylhexylglycerin
Skin ConditioningAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingXanthan Gum
EmulsifyingDisodium EDTA
Hydrolyzed Pearl
Skin ConditioningLauryl PEG-10 Tris(Trimethylsiloxy)Silylethyl Dimethicone
EmulsifyingCI 77499
Cosmetic ColorantSilica Dimethyl Silylate
EmollientBeeswax
Emulsion StabilisingBiotin
AntiseborrhoeicAstragalus Membranaceus Root Extract
EmollientScutellaria Baicalensis Root Extract
AstringentCnidium Officinale Root Extract
Skin ConditioningCentella Asiatica Extract
CleansingChamomilla Recutita Flower Extract
MaskingChamaecyparis Obtusa Leaf Extract
Skin ConditioningButyrospermum Parkii Butter Extract
Skin ConditioningSimmondsia Chinensis Seed Oil
EmollientCopper Gluconate
Skin ConditioningCaffeine
Skin ConditioningLauryl Glucoside
CleansingHydrolyzed Royal Jelly Protein
Skin ConditioningHydrolyzed Pea Protein
EmollientHydrolyzed Yeast Extract
Skin ConditioningSqualane
EmollientKaolin
AbrasiveHydrolyzed Corn Protein
Skin ConditioningHydrolyzed Rice Bran Protein
Skin ConditioningTocopherol
AntioxidantMadecassoside
AntioxidantMadecassic Acid
Skin ConditioningParfum
MaskingWater, Ethylhexyl Methoxycinnamate, Titanium Dioxide, Glycerin, Cyclopentasiloxane, Cetyl PEG/PPG-10/1 Dimethicone, 4-Methylbenzylidene Camphor, Butyl Methoxydibenzoylmethane, Ethylhexyl Salicylate, Niacinamide, Octocrylene, Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone, Cyclohexasiloxane, Polyglyceryl-6 Stearate, Silica, Cetyl Ethylhexanoate, Polyglyceryl-10 Laurate, 1,2-Hexanediol, Hydrolyzed Collagen Extract, Hydrolyzed Hyaluronic Acid, Portulaca Oleracea Extract, Allantoin, Adenosine, Tocopheryl Acetate, Phenoxyethanol, Panthenol, Sodium Hydroxide, Butylene Glycol, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Xanthan Gum, Disodium EDTA, Hydrolyzed Pearl, Lauryl PEG-10 Tris(Trimethylsiloxy)Silylethyl Dimethicone, CI 77499, Silica Dimethyl Silylate, Beeswax, Biotin, Astragalus Membranaceus Root Extract, Scutellaria Baicalensis Root Extract, Cnidium Officinale Root Extract, Centella Asiatica Extract, Chamomilla Recutita Flower Extract, Chamaecyparis Obtusa Leaf Extract, Butyrospermum Parkii Butter Extract, Simmondsia Chinensis Seed Oil, Copper Gluconate, Caffeine, Lauryl Glucoside, Hydrolyzed Royal Jelly Protein, Hydrolyzed Pea Protein, Hydrolyzed Yeast Extract, Squalane, Kaolin, Hydrolyzed Corn Protein, Hydrolyzed Rice Bran Protein, Tocopherol, Madecassoside, Madecassic Acid, Parfum
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterThis ingredient is also known as Octinoxate and is one of the oldest and most widely used chemical UV filters in skincare.
It has a simple job: soap up UVB radiation (290-320 nm), the wavelengths responsible for sunburn and a big chunk of long-term sun damage.
In formulas, it's always paired with a separate UVA filter because octinoxate solely protects skin from UVB.
Because it's an oil-soluble liquid, it's easy to blend into the oil phase of lotions/creams and gives a cosmetically elegant feel.
The one quirk about formulating this ingredient is photostability; the molecule slowly changes shape into a less effective version when sunlight hits it. So the longer you're in the sun, the weaker its protection gets. The drop can be more than 30% in some formulas.
It also doesn't play nice with Avobenzone (the common UVA filter) since avobenzone destabilizes octinoxate and the two degrade each other. But don't worry: brands have solved this issue by adding photostabilizers like Tinosorb S to prevent degradation and keep SPF stable under heavy UV exposure.
The maximum allowed level is 10% in the EU and Australia, 7.5% in the US and Canada, and 20% in Japan.
The Cosmetic Ingredient Review Panel has concluded this ingredient to be safe in cosmetics up to 10%.
One last thing worth knowing for context:
Octinoxate has been the subject of ongoing review in Europe where the Scientific Committee on Consumer Safety's (SCCS) 2025 final opinion is that this ingredient is an endocrine-active substance.
Lab and animal studies suggest it can act a bit like a hormone in the body (mildly mimicking estrogen and slightly blocking male hormones). It's important to know this hasn't really been shown to happen in everyday human use.
This ingredient is also banned in Hawaii over coral reef concerns.
Learn more about Ethylhexyl MethoxycinnamateTitanium Dioxide (TD) is a mineral UV filter widely used in sunscreens and cosmetics.
It's one of only two UV filters officially classified as "mineral" by regulatory agencies (the other being Zinc Oxide).
A really common myth is that mineral filters work by reflecting UV light off your skin like tiny mirrors.
They don't only do that; modern research shows TD protects mostly by absorbing UV radiation, the same way chemical filters do.
When researchers measured this, reflection accounted for only about 4-5% of the protection (and less than SPF 2 on its own). The other ~95% comes from absorption: the UV photons hit the particle and their energy gets soaked up by its semiconductor band gap rather than bouncing off.
So "reflects vs. absorbs" was never really the right way to split mineral from chemical filters.
TD gives broad-spectrum protection that's strongest in the UVB and UVA-2 range and weaker in the UVA-1 range. Its UVA protection isn't quite as strong as Zinc Oxide's which is why you'll often see the two paired together.
Together, they make a solid broad-spectrum system.
TD is a great pick for sensitive, acne-prone, or redness-prone skin because it's non-irritating and chemically inert. Regulatory reviews classify it as a non-sensitizer and mild-to-non-irritant.
It's also unlikely to cause the "eye sting" some chemical filters are known for.
The main trade-off is cosmetic; TD can leave a white cast and has a thicker texture. This is why mineral sunscreens are often less cosmetically elegant than chemical or hybrid formulas (and harder to shade-match on deeper skin tones).
Formulators often use micronized or nano-sized TD to cut down on white case and improve spreadability. Smaller particles scatter less visible light so the formula looks less chalky while still filtering UV.
TD is almost always bundled with coatings like Alumina, Silica, Stearic Acid, or Dimethicone. These coatings do two important jobs:
TD can be used at up to 25% in a finished sunscreen; this is the regulatory ceiling in both the US and the EU.
In practice, the amount in any given product varies a lot depending on the target SPF and whether it's paired with other UV filters.
TD is one of the most heavily vetted sunscreen ingredients out there. It is approved as a UV filter in all major markets worldwide, including the US, EU, UK, Japan, Korea, China, Australia, and Canada.
The safety evidence is solid. There was an old worry that nano particles might absorb through skin into the body but multiple studies (including on damaged, sunburned, and UV-irradiated skin) have shown that TD stays on the surface and the layer of dead skin cells on top of everything else.
There's also no evidence of carcinogenicity, mutagenicity, or reproductive toxicity from dermal exposure of this ingredient.
For those who have seen the headline about a 2022 EU ban on TD, that was on TD as a food additive (a complete separate use from topical sunscreen).
There are ongoing questions about how nano-TD might affect marine ecosystems. As of now, there has been no conclusive evidence that any form of TD (or any other sunscreen filter) harms coral reefs or marine life.
The science is still developing and it's a space worth watching rather than packing over.
However, several destinations have reef-safety sunscreen rules that restrict certain chemical filters and steer visitors toward mineral, non-nano options. If you're traveling somewhere with these rules, a non-nano mineral sunscreen is the safe bet.
Learn more about Titanium DioxideGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinCyclopentasiloxane (D5) is a lightweight silicone that mostly acts as an emollient and solvent in cosmetics. Its the reason your products feel silky, fast-spreading, and non-greasy.
Since D5 is volatile, it does its thing and then evaporates off the skin quickly.
The safety profile of this ingredient is reassuring; the US CIR Expert Panel concluded D5 is safe as used in cosmetics and Health Canada concluded that D5 is not harmful to human health or the environment as currently used in cosmetics
There's a study that people mention about D5 in a rat study showing tumors. This study is related to long-term inhalation of high D5 levels.
Regulatory bodies have judged this study to be not applicable in topical skincare since skin absorption of D5 is very low and we're not really inhaling huge amounts of D5.
The only restriction for this ingredient is environmental. The European Chemicals Agency (ECHA) restricted D5 in wash-off cosmetics at or above 0.1% due to their persistence in water.
Learn more about CyclopentasiloxaneThis ingredient is a silicone-based emulsifer that helps the water and oil phases play nicely together.
It's pretty effective because one end of the molecule loves oil and the other one loves water.
Besides holding formulas together, it also leaves a silky and lightweight feel on skin without the greasiness. A manufacturer also claims it can help with the controlled release of active ingredients.
The CIR Expert Panel found this ingredient to not be sensitizing in concentrations up to 15% in human maximazation testing and dimethicone-based compounds were not comedogenic.
It has a high molecular weight well above 1,000 g/mol which means it limits meaningful skin penetration.
A 2019 study specifically tested this ingredient and found no observable Malassezia growth in its presence.
Learn more about Cetyl PEG/PPG-10/1 DimethiconeThis ingredient is also known as enzacamene. It is a synthetic, oil-soluble UVB filter derived from camphor.
In cosmetics, it protects the skin against UVB radiation (290-320 nm) with a peak absorbance of 301 nm.
However, it is slightly photounstable and loses about 10% of its protective power after 65 minutes (but it can still stabilize the famously unstable avobenzone).
Historically, the maximum permitted usage concentration in the EU was 4% though it was banned in the US, Japan, and Denmark.
As of 2025, the European Commission has placed it on the list of prohibited substances.
This regulation change isn't about skin irritation or allergic reactions; the EU's Scientific Committee on Consumer Safety (SCCS) has concluded there's enough evidence to suggest it may mess with your hormones. There are also questions about whether it could damage DNA that scientists haven't been able to rule out yet.
At the same time, the UK's Scientific Advisory Group on Chemical Safety (SAG-CS) independently concluded that 4-MBC cannot be considered safe for use in cosmetic products at any concentration due to these same concerns.
Learn more about 4-Methylbenzylidene CamphorAlso known as Avobenzone, this ingredient is an oil-soluble used to absorb the full spectrum of UVA rays (peak 357 nm).
It's one of the most effective UVA filters available but has a major caveat of photostability: avobenzone is susceptible to photodegradation.
This means it can lose efficacy when exposed to sunlight without the help of a stabilizing agent.
Studies show antioxidants (like vitamin E or vitamin C) and some UV filters (like octocrylene and Tinosorb S) can meaningfully improve its stability in a formulation.
The maximum allowable concentration according to regulation is 3% in the US + Canada, and 5% in the EU, Australia, China, Korea, and ASEAN countries.
It has a well-support safety profile: a comprehensive 2025 review found minimal toxicity with no evidence of carcinogenicity.
Overall, avobenzone is a safe and regulated ingredient used in sunscreen for over 40 years.
Learn more about Butyl MethoxydibenzoylmethaneEthylhexyl Salicylate (also called Octisalate or Octyl Salicylate) is an oil-soluble organic UV filter that's been used in sunscreen since the 1950's.
It absorbs UVB light in the 280-320 nm range with a peak absorbance around 306 nm.
You'll often see it paired with other UV filters to boost overall SPF because octisalate is a fairly week filter on its own.
The reason you'll see it so often is because it can help solubilize and stabilize the trickier filters like oxybenzone and avobenzone.
Unlike these filters, octisalate has pretty good photostability and doesn't create skin-damaging free radicals when exposed to sunlight.
The fatty-alcohol part of the molecule also gives it a light, emollient feel so it doubles as a nice texture enhancer.
Usage levels vary around the world:
Safety-wise, this ingredient has a pretty reassuring track record. The EU's Scientific Committee on Consumer Products (SCCP) found very low skin penetration in human skin tests and negative results for irritation, phototoxicity, and photoallergy.
The real-world allergy risk is pretty low too; a 2012 European study of 1,031 people recorded only 2 reactions to it (a rate of 0.19%).
You might have seen scary headlines about sunscreen getting into your blood.
In 2019, the FDA found that several chemical filters can absorb through the skin and show up in the bloodstream at small but measurable levels.
Here's the important part: these tiny levels are just a cutoff the FDA uses to decide which ingredients need more testing and doesn't mean anything harmful was found.
The researchers were clear that the results are no reason to stop wearing sunscreen.
Learn more about Ethylhexyl SalicylateNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideOctocrylene is an oil-soluble organic UV filter that mainly absorbs UVB and short wave UVA II light.
Its real superpower is teamwork: octocrylene is remarkably photostable and is most famous for stabilizing avobenzone (the workhorse UVA filter).
This ingredient is commonly used to enhance both UVB and UVA protection due to its unique property in stabilizing avobenzone. It also pulls double duty by boosting water resistance and giving formulas a smooth, spreadable feel.
The EU's Scientific Committee on Consumer Safety (SCCS) has deemed octocrylene to be safe as a UV-filter at concentrations up to 10% (capped at 9% in propellant sprays). The US also permits it up to 10%.
Two things worth knowing:
You'll usually see this ingredient used in concentrations between 2-10% (higher amounts when used as a stabilizer for avobenzone).
Learn more about OctocrylenePolyglyceryl-3 Polydimethylsiloxyethyl Dimethicone is a type of silicone.
Cyclohexasiloxane is a type of silicone more commonly known as D6. It is an emollient and solvent.
Cyclohexasiloxane is used to evenly distribute ingredients throughout the product. When applied to the skin, Cyclohexasiloxane evaporates and leaves behind a silky feel.
As an emollient, it can help the skin feel soft and hydrated. It is also used to reduce frizz in hair products.
Learn more about CyclohexasiloxanePolyglyceryl-6 Stearate isn't fungal acne safe.
Silica, also known as silicon dioxide, is a naturally occurring mineral. It is used as a fine, spherical, and porous powder in cosmetics.
Though it has exfoliant properties, the function of silica varies depending on the product.
The unique structure of silica enhances the spreadability and adds smoothness, making it a great texture enhancer.
It is also used as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.
In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. When you rub them in, they lightly polish away dead skin layers and enhance the penetration of active ingredients.
Learn more about SilicaCetyl Ethylhexanoate is an emollient ester. It comes from cetearyl alcohol and 2-ethylhexanoic acid.
Cetyl Ethylhexanoate is an emollient that adds a velvety feel to skin without being greasy or oily. Emollients help trap moisture into your skin, keeping your skin soft and hydrated.
Polyglyceryl-10 Laurate is a cleansing agent and emulsifier.
It rounds up dirt, oil, and grime, so they can be rinsed off easily as a cleanser.
On the emulsifier side, it keeps your formula smooth and well-mixed by playing peacekeeper for ingredients that don't naturally get along (like oil and water).
Because it has a C12 (lauric acid) fatty acid chain, this ingredient can potentially feed the Malassezia yeast that causes fungal acne. The Malassezia yeast prefers esters with C11-C24 fatty acids.
This ingredient is an ester of lauric acid and Polyglycerin-10.
Learn more about Polyglyceryl-10 Laurate1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Hydrolyzed Collagen Extract can help to reduce the effects of aging.
Hydrolyzed Hyaluronic Acid is hyaluronic acid (HA) that is broken down into lower molecular weight fragments.
It's a humectant that pulls and holds water in the skin to help with hydration, plumpness, and reduce transepidermal water loss.
Because hydrolyzed hyaluronic acid is smaller in size, it can slip past your outermost layer of skin more easily than full-sized HA.
Most formulations will combine all sizes to get the best of both worlds.
Typical usage levels range from 0.01-1%. Any percentage higher than 2% might become goopy and tacky.
Learn more about Hydrolyzed Hyaluronic AcidThis extract comes from Purslane, a succulent. It has anti-inflammatory, antioxidant, and hydrating properties.
Purslane is very nutritious. It contains omega-3 fatty acids, NMFs, many vitamins, minerals, and antioxidants. The vitamins found in purslane include: Vitamin C, Vitamin A, and Vitamin E.
Fun fact: Purslane is a succulent with an extensive habitat. It is used in traditional Korean medicine to treat irritated skin.
Nowadays, purslane is becoming a superfood due to its highly nutritious content.
Learn more about Portulaca Oleracea ExtractAllantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Learn more about AllantoinAdenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineTocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Learn more about Tocopheryl AcetatePhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolPanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinAcrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Learn more about Acrylates/C10-30 Alkyl Acrylate CrosspolymerXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAWe don't have a description for Hydrolyzed Pearl yet.
Lauryl PEG-10 Tris(Trimethylsiloxy)Silylethyl Dimethicone is a type of silicone.
Ci 77499 is also hydrated iron III oxide. It is created from mixing red and black iron oxides. This helps give shades of darkness to a product.
Iron III oxides are classified as inorganic chemicals for coloring.
This silica is mainly used to thicken oils and suspend particles in oils. It is not water soluble.
According to the manufacturer, it:
The manufacturer also claims this ingredient to be useful in makeup.
In lipstick formulations, this ingredient improves color payoff, reduces pigment settling, and reduces oil bleeding. This ingredient also improves the grip of powder products such as dry shampoos.
Learn more about Silica Dimethyl SilylateBeeswax is natural wax produced by honey bees to build their honeycomb.
Because it forms a protective layer on your skin, it can help lock in moisture and reduce water loss. It is also widely used as a thickener and emulsifier in lip balms and lotions. Research suggests beeswax containing moisturizers can support skin barrier integrity.
In comedogenic testing, Beeswax scored a 0-2, which is on the low end. Whether or not a product clogs your pores really comes down to the formula as a whole (not any single ingredient on its own).
Cera Alba is the white, bleached form of this ingredient.
Just so you know, beeswax is not vegan since it is animal-derived. It cannot be removed with water, but can be taken off with an oil cleanser.
People with a known Propolis allergy also report to have reactions from beeswax.
Beeswax's wax esters are derived primarily from palmitic and oleic acid (C16 and C18:1). Both of these fall within the C11-C24 feeding window.
The Malassezia yeast can potentially cleave these esters and release usable fatty acids, so this ingredient may not be fungal acne safe. However, not everyone will react to this ingredient.
Learn more about BeeswaxBiotin is a B vitamin that is naturally produced by our bodies. It is also called Vitamin H.
Our bodies use biotin in the metabolism process. It also helps our bodies use enzymes and move nutrients around. A biotin deficiency can lead to brittle hair and nails.
More research is needed on applying biotin topically. However, taking biotin orally has been shown to help nourish the skin, hair, and nails. They play a role in forming skin-hydrating fatty acids.
Biotin is water-soluble. It can be found in foods such as fish, eggs, dairy, nuts, and meat. Vitamin H stands for "haar" and "haut". These are the German words for hair and skin.
Learn more about BiotinAstragalus Membranaceus Root Extract is from an herb called Huang Qi. The roots of this plant have traditionally used in traditional Chinese medicine.
This ingredient contains hydrating, antioxidant, and anti-inflammatory compounds such as polysaccharides, saponins, and flavonoids. These compounds have also been studied for its effects on skin repair like fibroblast activity, growth-factor signaling, and wound closure models. However, human evidence is still limited.
Recent clinical work on a proprietary Astragalus + Centella saponin system showed improvement in skin aging and quality.
Overall, this ingredient is a great supportive ingredient with low irritation risk.
Learn more about Astragalus Membranaceus Root ExtractScutellaria Baicalensis Root Extract comes from the Baikal skullcap or Chinese skullcap plant. This plant is native to Northeast Asia and can be found in China, Mongolia, Korea, and Siberia.
In cosmetics, Scutellaria Baicalensis Root Extract provides antioxidant and anti-inflammatory benefits. This is due to the flavonoid composition of Scutellaria Baicalensis Root Extract.
In Chinese traditional folk medicine, Scutellaria Baicalensis Root Extract is used to help treat lung issues and hypertension.
Learn more about Scutellaria Baicalensis Root ExtractWe don't have a description for Cnidium Officinale Root Extract yet.
Centella Asiatica Extract (Centella) is one of the most researched botanical extracts in skincare with decades of studies backing its effects on inflammation, collagen, and the skin barrier.
That research keeps pointing back to the same four triterpenoid saponins: Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid.
These compounds allow centella to dial back inflammation, encourage the skin to build and hold onto collagen, support the barrier and hydration, and bring solid antioxidant activity to protect against signs of aging.
Centella also carries a nice supporting cast of Vitamin A, vitamin C, several B vitamins, and amino acids. Put it all together and you get an ingredient that soothes, hydrates, and protects, all at once.
Most of centella's magic comes from the four big compounds (Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid). These are the actives doing the heavy lifting in almost every centella study.
Here is the short version of what they do in the skin:
So it is not just soothing for the sake of soothing. Centella calms the skin AND helps it rebuild.
Just FYI, not all centella on an ingredient list is the same. What you are getting actually depends on the extract:
Fun fact on the ratios: the leaves tend to be richest in Madecassoside and Asiaticoside, and lower in the two acids. The exact amounts shift with where the plant is grown and how it is processed. This means purity really does vary brand to brand.
Centella is one of the most easygoing actives out there.
It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs nicely with stronger actives like retinoids and exfoliating acids where it can help take the edge off irritation.
On the safety side, centella and its triterpenes are classified as weak sensitizers, meaning allergic reactions are possible but uncommon.
Patch tests at 1% and 5% came back negative in test panels, and creams at typical use levels did not cause allergic reactions across large groups of people.
But as with any new active, a patch test is still a smart move for very reactive skin.
Centella is widely used because it is effective at low percentages. For context, human safety testing found no meaningful irritation from creams containing centella extract at everyday use levels (the tested amounts were well under 1%).
The irritancy threshold in animal testing was also above 30% (so real-world formulas sit far below anything concerning).
In collagen lab studies, higher concentrations drove more collagen synthesis, so serums built around centella tend to feature it more prominently.
Bottom line: you will find centella working nicely anywhere from a fraction of a percent up to hero-ingredient levels depending on whether it is a supporting soother or the main event.
Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica ExtractChamomilla Recutita Flower Extract comes from the Chamomile flower.
Chamomile is rich in antioxidants and has anti-inflammatory properties. Several compounds found in chamomile help with soothing, such as bisbolol.
Antioxidant components in chamomile make it an effective ingredient to help slow the signs of aging. Antioxidants help fight free-radical molecules, or molecules that may damage your skin.
Essential oils from chamomile have been found to improve wound healing due to its antimicrobial properties.
Ancient Greeks and Egyptians used Chamomile to treat skin redness and dryness. Chamomile has also been used to help treat stomach issues.
Learn more about Chamomilla Recutita Flower ExtractThis ingredient comes from the leaves of the Japanese cypress tree that is also called Hinoki. The leaves are rich in flavonoids with quercitrin being one of its key actives.
A 2023 study tested a 70% ethanol extract on UVA-stressed, collagen-producing skin cells. Across multiple antioxidant tests, this extract protected skin from free radicals at meaningful rates.
And the coolest part? At 1000 µg/mL, it blocked two enzymes (collagenase and elastase) almost as well as vitamin C did at the same dose. Collagenase and elastase are the enzymes that break down your skin's collagen and elastin over time.
The same study found this ingredient lowered skin-breakdown enzymes and inflammation signals while bumping up collagen production in UV-stressed cells.
A 2024 follow-up tested a fermented version (fermented with mushroom) and it calmed down several key inflammation markers in irritated immune cells. So besides anti-aging, this ingredient can also help soothe skin.
Most of the data right now is still at the cell-culture stage rather than from human clinical trials. However, there's no harm in adding this ingredient to your routine.
Just be sure to patch test if you have a history of sensitivity toward botanical extracts.
Learn more about Chamaecyparis Obtusa Leaf ExtractButyrospermum Parkii Butter Extract is from the fruit of the Shea Tree. It is an effective skin hydrator and emollient.
Shea butter is rich in antioxidants. Antioxidants help fight free-radicals, or molecules that may harm the body. It is also full of fatty acids including stearic acid and linoleic acid. These acids help replenish the skin and keep skin moisturized.
Jojoba oil is one of the most well-studied plant-derived ingredients in cosmetics. It is an emollient with a special structure.
Because it is made up of 97-98% wax esters, it closely mirrors the linear monoesters found in human sebum. This makes it skin compatible, non-greasy, and lightweight.
Unlike other plant oils, jojoba wax doesn't easily penetrate skin. It mostly works in the uppermost layers as an emollient. This just means it forms a light barrier on the skin to help retain moisture.
Formulations with jojoba esters up to 90% reduced transepidermal water loss (TEWL) and increased barrier recovery by 81% (outperforming bisabolol at 47%).
Besides barrier support, the science also suggests jojoba to have anti-inflammatory effects and potential applications for skin infections, aging, and wound healing.
Fun fact: Indigenous cultures have used jojoba as a moisturizer and to help treat burns for centuries.
Fungal acne: The Malassezia yeast is known to metabolize fatty acids in the C11-24 range and jojoba's dominant fatty acid components fall into this range. This ingredient may not be fungal acne safe.
Learn more about Simmondsia Chinensis Seed OilThis ingredient is a copper salt known for its wound healing properties.
Our bodies use copper to help stabilize our skin's collagen and elastin. Its also an essential for superoxide dismutase, an enzyme with strong antioxidant properties.
Copper has wound healing properties due to its role in creating new blood vessels and tissue repair.
Learn more about Copper GluconateCaffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.
As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.
Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.
You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.
Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.
Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.
Learn more about CaffeineLauryl Glucoside sugar- and lipid-based cleansing agent. It is created from glucose and lauryl alcohol.
This ingredient is a surfactant, making it easier to rinse oil, dirt, and other pollutants away.
A British study found lauryl glucoside to cause skin sensitivity for some people. We recommend speaking with a professional if you have concerns.
Other names for this ingredient include "Lauryl Polyglucose", "Lauryl glycoside", and "D-Glucopyranoside".
Learn more about Lauryl GlucosideWe don't have a description for Hydrolyzed Royal Jelly Protein yet.
Hydrolyzed pea protein has skin conditioning and emollient properties. It is created by cutting protein fragments (peptides) into smaller pieces.
According to a manufacturer, this size of this ingredient makes it easy to be absorbed into skin where they strengthen the skin barrier, improve moisture retention, and improve signs of irritation.
One study that included pea proteins in a topical product reported improved atopic dermatitis symptom scores while a patent containing this ingredient suggests this ingredient to support hydration-related pathways in the skin.
Learn more about Hydrolyzed Pea ProteinWe don't have a description for Hydrolyzed Yeast Extract yet.
Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Learn more about SqualaneKaolin is a clay. It is used for oil control and to help minimize pores. Like other clays, kaolin has the ability to absorb excess sebum or oil. This can help clean out pores and mattify the skin.
Some types of kaolin may have exfoliating properties. When water is added to kaolin, it becomes a paste with small abrasive particles.
Most kaolin is a white color, but may be pink/orange/red depending on where it comes from.
The name 'kaolin' comes from a Chinese village named 'Gaoling'. Kaolin clay comes from rocks rich in kaolinite. Kaolinite, the mineral, has a silicate layered structure. Kaolinite is formed from chemical weathering of aluminum siilicate minerals.
Besides skincare, kaolin is commonly used to make glossy paper, in ceramics, toothpaste, and as medicine to soothe stomach issues.
Learn more about KaolinWe don't have a description for Hydrolyzed Corn Protein yet.
We don't have a description for Hydrolyzed Rice Bran Protein yet.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolMadecassoside is one of four active compounds found in Centella asiatica and is one of the main reasons Centella is so effective at calming irritated skin and supporting the moisture barrier.
There's a solid body of peer-reviewed research backing Madecassoside for several skin benefits. Studies have found:
Madecassoside pairs well with other hydrating or antioxidant ingredients like Ascorbic Acid or Hyaluronic Acid.
Learn more about MadecassosideMadecassic Acid is one of the four star actives in Centella Asiatica. In skincare, it earns its keep as a calming and repairing ingredient.
It works through the same core pathways as the rest of the centella family.
First, it turns down inflammation so it helps with things like redness and general upset skin.
Second, it acts as an antioxidant which means it helps protect skin from daily stress and damage.
And third, it nudges the skin to make more collagen and rebuild its support structure.
That combination is why the whole Centella family is known for calming skin, strengthening the barrier, fading redness, and giving anti-aging benefits.
It's worth being honest about the evidence here; a lot of the strongest data is on the full extract or a Madecassoside/Asiaticoside rather than Madecassic Acid alone. Reviewers also note more long-term clinical trials are needed to confirm the full potential.
Concentration-wise, this ingredient is rarely used pure and usually shows up as part of a standardized centella extract where reported content ranges from 0.02-3.06%.
Finished products typically run somewhere in the 0.1-10% range depending on the format.
In real-world tolerance tests, a repeat-insult patch test on an eye lotion with 0.2% Centella extract showed no irritation or allergic contact dermatitis in 54 subjects. And a mascara with 0.5% Madecassoside caused neither irritation nor sensitization in 109 subjects.
Allergy risk is very low, but not zero. Centella and its constituents are classified as weak contact sensitizers and some rare cases of allergic contact dermatitis exist.
Learn more about Madecassic AcidParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumReviews
No written reviews yet. Be the first to review this product.
Recent searches
Search reviews by skin type, ingredient, or keyword.
Where it's from
Labiotte is a Korean brand
50 SPF Rating
With an SPF rating of 50, this product protects against 98.0% of UVB rays
Often compared with
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated June 3, 2025 • Added by mint2