Versus

Sesderma Sesretinal Liposomal Serum Versus ISDIN Isdinceutics Retinal Intense Serum

Serum
Serum
Spanish Brand Spain
Spanish Brand Spain

Updated on May 31, 2024

Overview

What they are

These products are both cruelty-free and reef safe serums. They have a total of 10 ingredients in common

Cool Features

They both contain peptides, retinoid and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any common allergens or parabens

What's Inside

They both contain harsh alcohols, fragrances and silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Sesretinal Liposomal Serum

Water

Skin Conditioning

Bis-PEG-18 Methyl Ether Dimethyl Silane

Emollient

Hydrogenated Polydecene

Emollient

Ceteth-20

Cleansing

Propanediol

Solvent

C12-15 Alkyl Benzoate

Antimicrobial

Cyclopentasiloxane

Emollient
Silicon Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Gluconolactone

Skin Conditioning
PHA IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1

Skin Conditioning
Peptide Icon

Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-5

Skin Conditioning
Peptide Icon

Nicotiana Benthamiana Sh-Polypeptide-15 Hexapeptide-40

Skin Conditioning
Peptide Icon

Alcohol

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon

Bakuchiol

Antimicrobial
Antioxidant IconHelps with Anti-Aging IconHelps brighten skin Icon

BHT

Antioxidant
Antioxidant Icon

Bidens Pilosa Extract

Humectant

Carbomer

Emulsion Stabilising
1 / 0

Ceramide AP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide EOP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Copper Sulfate

Skin Conditioning
Sulfate Icon

Dipotassium Phosphate

Buffering

Disodium EDTA

Elaeis Guineensis Oil

Emollient
Oil IconNot safe for Fungal Acne Icon

Ethylhexylglycerin

Skin Conditioning

Glucosamine Hcl

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Glycolic Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Glycyrrhetinic Acid

Skin Conditioning

Gossypium Herbaceum Seed Oil

Skin Conditioning
3 / 2 Oil IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Hydrochloric Acid

Buffering

Lactic Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Linum Usitatissimum Seed Oil

Perfuming
Fragrance IconOil IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon

Lycium Barbarum Fruit Extract

Astringent

Mandelic Acid

Antimicrobial
AHA IconGood for Oily Skin IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Niacin

Smoothing
Helps hydrate Dry Skin IconGood for Dark Spots Icon

Nicotiana Benthamiana Sh-Polypedtide-7

Skin Conditioning

Parfum

Masking
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Phenoxyethanol

Preservative
Preservative Icon

Phosphatidylcholine

Emulsifying

Phytosphingosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Potassium Phosphate

Buffering

Potassium Sorbate

Preservative
Preservative Icon

Retinal

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Retinyl Palmitate

Skin Conditioning
1-3 / 1-3 Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconNot safe for Fungal Acne IconMay worsen Rosacea Icon

Sodium Benzoate

Masking
Preservative Icon

Sodium Chloride

Masking
Can worsen Dry Skin IconBad for Acne Prone Skin IconMay worsen Rosacea Icon

Sodium Cholate

Skin Conditioning

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Sodium Hydroxide

Buffering

Sodium Lauroyl Lactylate

Emulsifying

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Triethanolamine

Buffering
2 / 0

Tromethamine

Buffering

Xanthan Gum

Emulsifying

Zinc Chloride

Soothing
Isdinceutics Retinal Intense Serum

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Antimicrobial, Antioxidant, Emollient

Bakuchiol is a plant-derived antioxidant (it's vegan!). It is often called the replacement for retinol although it is not part of the same family.

It has similar effects as retinol: skin smoothing, reducing discoloration, and preventing wrinkles. It does not cause as much irritation as traditional retinoids.

Bakuchiol works by breaking down free radicals and stimulating collagen production in skin.

Combining bakuchiol with retinol will not have adverse side effects. Studies show using them will just boost the benefits. Bakuchiol is also found to help stabilize retinol.

While bakuchiol does not make the skin more sun sensitive, we recommend wearing SPF on a daily basis.

Read more about traditional retinol

Learn more about Bakuchiol

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Masking, Perfuming

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Learn more about Parfum
Skin Conditioning

Retinal is a form of retinoid. Retinoids are the gold-standard class of anti-aging ingredients.

Retinal has many benefits as other retinoids: improve skin texture, reduce large pores, reduce the effects of aging, reduce the visibility of dark spots, heal scars, and fight acne.

Studies show retinal may work at a faster rate than retinol due to its structure.

All retinoids have to be converted into retinoic acid before starting to work. Some retinoids take several steps of conversion before binding. Retinal is only one step away, making it more potent.

Like other retinoids, retinal may be irritating. It is best to ease into using this ingredient frequently.

Using the 'ramp up' method, start by using retinol once a week. This gives your skin time to adjust and decrease irritation. Once you feel ready, you can slowly increase the frequency of retinol use.

Using retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

Learn more about Retinal
Antioxidant, Masking, Skin Conditioning

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol
Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum

When to use

1 Routine
0% use in am
100% use in pm
100% use every other_day
18 Routines
0% use in am
100% use in pm
67% use every day