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Perricone MD Cold Plasma+ Advanced Serum Concentrate Ingredients Explained

3.0   from 1 ratings
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Published on July 13, 2020

Overview

What it is

Serum with 35 ingredients that contains AHA, hyaluronic acid, peptides, retinoid and Vitamin C

Cool Features

It is cruelty-free and reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

It doesn't contain any harsh alcohols, common allergens, parabens or sulfates

Fun facts

Perricone MD is from United States. This product is used in 4 routines created by our community.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

You should know

Here's our breakdown of the notable ingredients, benefits, and concerns we determined from the ingredients in this product. Click any item to learn more.

Notable Ingredients

AHA
Retinoid
Vitamin C
Hyaluronic Acid
Peptides (3)

Benefits

Hydrating (2)
Good For Oily Skin (2)
Redness Reducing
Skin Texture (3)
Reduces Large Pores (2)
Anti-Aging (4)
Dark Spots (3)
Scar Healing (2)
Acne Fighting
Brightening (2)

Concerns

Drying
May Worsen Oily Skin (4)
Acne Trigger (2)
Irritating (2)
Rosacea
Eczema

Ingredient Info

Click any item below to learn more and view relevant ingredients.
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free

Ingredients Overview

Here's our quick-to-read summary of the ingredients in this product. Keep scrolling if you'd like to learn more about what each ingredient does!
Ingredient
Features
1
Skin Conditioning, Solvent
2
Humectant, Skin Conditioning, Skin Protecting, Solvent
0 / 0
Helps hydrate Dry Skin IconHelps brighten skin Icon
3
Emollient, Masking
3-4 / 1
May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
4
Emollient, Emulsifying, Emulsion Stabilising
2 / 1
Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
5
Emollient, Emulsifying
1 / 0
Not safe for Fungal Acne Icon
6
0 / 0
Not safe for Fungal Acne Icon
7
Humectant, Masking, Skin Conditioning, Solvent
1 / 0
8
Emulsifying, Skin Conditioning
9
Antioxidant, Emollient, Skin Conditioning
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Dark Spots IconNot safe for Fungal Acne Icon
10
Buffering
11
Humectant, Skin Conditioning
Peptide Icon
12
Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
13
Masking, Skin Conditioning
14
Buffering
AHA IconGood for Oily Skin IconMay cause irritation IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconMay worsen Rosacea IconHelps brighten skin Icon
15
Emollient, Masking, Skin Conditioning
0 / 0
Oil IconHelps hydrate Dry Skin IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon
16
Skin Conditioning
17
Skin Conditioning
18
Antimicrobial, Masking, Skin Conditioning
19
Skin Conditioning, Skin Protecting
20
Humectant, Skin Conditioning
0 / 0
Hyaluronic Acid Icon
21
Skin Conditioning
1-3 / 1-3
Retinoid IconCan worsen Dry Skin IconGood for Oily Skin IconMay cause irritation IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconNot safe for Fungal Acne IconHelps fight Acne Icon
22
Skin Conditioning, Solvent
Oil IconNot safe for Fungal Acne Icon
23
Skin Protecting
24
Skin Conditioning
Peptide IconHelps with Anti-Aging Icon
25
Emollient, Skin Conditioning, Skin Protecting
1 / 0
Silicon Icon
26
27
Emulsion Stabilising, Gel Forming
1 / 0
28
Cleansing, Emulsifying
2 / 3
May worsen Oily Skin Icon
29
Emollient, Skin Conditioning, Solvent
Silicon Icon
30
Emollient, Humectant, Skin Conditioning
31
Emollient, Skin Conditioning, Solvent
Silicon Icon
32
Emulsifying
0 / 0
Not safe for Fungal Acne Icon
33
Emulsifying, Masking, Perfuming, Skin Conditioning
0-3 / 0
Fragrance IconOil IconNot safe for Fungal Acne Icon
34
Preservative
Preservative Icon
35
Preservative
Preservative IconMay worsen Eczema Icon

Ingredients Explained

This product contains 35 ingredients. Click on any ingredient to learn more about it
1
What it does: Skin Conditioning, Solvent
Community Rating: Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
2
What it does: Humectant, Skin Conditioning, Skin Protecting, Solvent
Community Rating: Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
3
What it does: Emollient, Masking
Community Rating: Very Disliked

Isopropyl Palmitate is a texture enhancer and emollient. It is an ester of isopropyl alcohol and palmitic acid.

Palmitates are emollients. Emollients help keep your skin soft and smooth by creating a barrier that traps moisture in.

When added to cosmetics, Isopropyl Palmitate creates a silky texture and improves spreadability.

Isopropyl Palmitate may not be fungal acne safe. It can worsen acne prone skin.

Learn more about Isopropyl Palmitate
4
What it does: Emollient, Emulsifying, Emulsion Stabilising
Community Rating: Very Disliked

Cetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.

Cetearyl alcohol is an emollient. Emollients help soothe and hydrate the skin by trapping moisture.

Studies show Cetearyl alcohol is non-toxic and non-irritating. The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient is usually derived from plant oils such as palm, vegetable, or coconut oils. There is debate on whether this ingredient will cause acne.

Due to the fatty acid base, this ingredient may not be Malassezia folliculitis safe.

Learn more about Cetearyl Alcohol
5
What it does: Emollient, Emulsifying
Community Rating: Disliked

Glyceryl Stearate is a mix of glycerin and stearic acid.

Glyceryl Stearate is used to stabilize the mixing of water and oil ingredients. By preventing these ingredients from separating, it can help elongate shelf life. It can also help thicken the product's texture.

As an emollient, it helps soften skin and supports barrier-replenishing ingredients.

In cosmetics, Glyceryl Stearate is often made from vegetable oils or synthetically produced. The human body also creates Glyceryl Stearate naturally.

Learn more about Glyceryl Stearate
6
What it does:
Community Rating: Very Disliked

Peg-100 Stearate is an emollient and emulsifier. PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.

Peg-100 Stearate helps keep skin soft by trapping moisture in. It helps prevent oil and water from separating in a product. By binding oil and water, it helps remove dirt and oil to be rinsed away.

7
What it does: Humectant, Masking, Skin Conditioning, Solvent
Community Rating: Mixed

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.

Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.

8
What it does: Emulsifying, Skin Conditioning

Phosphatidylcholine is a type of phospholipid. Phospholipids are naturally found in our skin as they are the main component of cell membranes. Phospholipids are skin-replenishing.

This ingredient can be found in the Lecithin of soybeans.

9
What it does: Antioxidant, Emollient, Skin Conditioning
Community Rating: Liked

Ascorbyl Tetraisopalmitate is a version of ascorbic acid, or pure Vitamin C.

Ascorbyl Tetraisopalmitate has many benefits including reducing wrinkles, skin soothing, dark spot fading, and fighting against free radicals.

Ascorbyl Tetraisopalmitate interferes with the process of skin darkening, helping to reduce hyperpigmentation. It also encourages the skin to produce more collagen.

As an antioxidant, it helps fight free-radicals. Free-radicals are molecules that may damage your skin cells.

One study found Ascorbyl Tetraisopalmitate to degrade in sunlight, but is stabilized when conbined with acetyl zingerone.

Learn more about Ascorbyl Tetraisopalmitate
10
What it does: Buffering
Community Rating: Liked

We don't have a description for Dimethyl Mea.

11
What it does: Humectant, Skin Conditioning
Community Rating: Loved

Acetyl Hexapeptide-8 is a peptide. A common name for this peptide is Argireline.

Argireline has a similar function to botox. It prevents muscle movement and contractions. By preventing muscles from moving, Argireline also prohibits the formation of fine lines and wrinkles. However, research is lacking in proving this ingredient to be as effective as botox.

Argireline tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.

Read more about other common types of peptides here:

Learn more about Acetyl Hexapeptide-8
12
What it does: Skin Conditioning
Community Rating: Liked

Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.

Palmitoyl Tripeptide-1 is a signal peptide. This means it tells our skin to create collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.

Palmitoyl Tripeptide-1 can help reduce wrinkles and make the skin look more youthful.

Read more about other common types of peptides here:

Learn more about Palmitoyl Tripeptide-1
13
What it does: Masking, Skin Conditioning
Community Rating: Loved

We don't have a description for Tyrosine.

14
What it does: Buffering
Community Rating: Loved

Glycolic Acid is arguably the most famous AHA with research to back up its benefits. Its main role is to peel the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and look more even.

Glycolic Acid has shown to boost collage production, a protein that helps skin stay firm. Overall, Glycolic Acid helps with improving uneven tone, rough patches of skin, fine lines, wrinkles, and sun damage. It also increases skin hydration by playing a role in creating molecules that create hyaluronic acid naturally.

When applying Glycolic Acid, it is normal to feel slight stinging. The pH value and concentration of glycolic acid play a role in the effectiveness of the product.

Recent studies have shown Glycolic Acid may protect the skin against UV damage. However, you should always wear SPF, especially when using exfoliants.

Read more about some other popular AHA's here:

Learn more about Glycolic Acid
15
What it does: Emollient, Masking, Skin Conditioning
Community Rating: Disliked

Helianthus Annuus Seed Oil is the oil derived from the seeds of a Sunflower. Sunflower seed oil is non-fragrant. It is an emollient, meaning it helps to soften the skin.

Sunflower seed oil contains many fatty acids. The fatty acids found in sunflower seeds include (from highest amount to least): linoleic acid, myristic acid, palmitic acid, stearic acid, arachidic acid, oleic acid, and linolenic acid.

These fatty acids help the skin create ceramides. Ceramides play a role in repairing the skin barrier.

Helianthus Annuus Seed Oil helps moisturize the skin. This in turn helps the skin look more rejuvenated and smoother.

Sunflowers are rich in vitamin E.

Historians believe Indigenous cultures of North America domesticated sunflowers before corn. Thus they relied on sunflower oil for a variety of uses. One such use is moisturizing skin and hair.

Sunflower seed oil may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.

Learn more about Helianthus Annuus Seed Oil
16
What it does: Skin Conditioning

We don't have a description for Magnesium Aspartate.

17
What it does: Skin Conditioning
Community Rating: Loved

We don't have a description for Zinc Gluconate.

18
What it does: Antimicrobial, Masking, Skin Conditioning
Community Rating: Mixed

Rosmarinus Officinalis Leaf Extract comes from rosemary. Rosemary is native to the Mediterranean.

While Rosmarinus Officinalis Leaf Oil can be volatile due to its fragrant properties, this component is usually removed in the leaf extract.

Rosemary Leaf Extract can help protect your skin against damage from free-radical molecules. It contains many antioxidants such as rosmarinic acid and caffeic acid. Rosemarinic acid has been found to help soothe skin conditions such as eczema and acne.

Learn more about Rosmarinus Officinalis Leaf Extract
19
What it does: Skin Conditioning, Skin Protecting
Community Rating: Loved

We don't have a description for Copper Gluconate.

20
What it does: Humectant, Skin Conditioning
Community Rating: Loved

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
21
What it does: Skin Conditioning
Community Rating: Mixed

Retinyl palmitate is a form of retinoid. It is created from palmitic acid and retinol.

This ingredient has antioxidant and exfoliating properties. Like other types of retinols, retinyl palmitate increases cell turnover. Removing dead skin cells and encouraging the growth of new ones improves skin tone and unclogs pores. This in turn promotes brighter looking skin and even skin texture.

As an antioxidant, retinyl palmitate helps neutralize free-radical molecules. These molecules have the potential to damage skin cells. Thus, antioxidants may help with anti-aging.

Retinyl palmitate can be good for be good for oily skin by helping to unclog pores. However, it may not be good for dry skin and fungal acne.

After using this product, you should follow up with sunscreen.

This ingredient is often added to low-fat milk to increase the levels of Vitamin A.

Learn more about Retinyl Palmitate
22
What it does: Skin Conditioning, Solvent
Community Rating: Disliked

Echium Plantagineum Seed Oil is an oil and isn't fungal acne safe.

23
What it does: Skin Protecting

We don't have a description for Hydrolyzed Myrtus Communis Leaf Extract.

24
What it does: Skin Conditioning
Community Rating: Loved

Copper Tripeptide-1 is a peptide naturally found in body fluids. Peptides are building blocks for protein.

Studies show this ingredient tells our body to create more collagen and elastin. Collagen is a protein that makes connective tissue. Elastin is the protein responsible for giving our skin elasticity. Our bodies start to slow down collagen and elastin production with age.

Boosting collagen and elastin production can help create a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin. It's a win-win situation!

Studies show this ingredient can help with scar healing. This is because it breaks down damaged collagen, the main component of scar tissue. It may also help with reducing sunspots, acne scars, and uneven skin tone.

This ingredient is also an antioxidant. Antioxidants help the body fight off free-radicals. Free radicals are molecules that damage our cells, such as pollution and tobacco smoke.

More benefits: Copper Tripeptide-1 helps maintain tissues in blood vessels and promote natural hyaluronic acid in skin.

Read more about other common types of peptides here:

Learn more about Copper Tripeptide-1
25
What it does: Emollient, Skin Conditioning, Skin Protecting
Community Rating: Very Disliked

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

Dimethicone has been found increase absorption in skin, boosting the benefits of other ingredients. While there is concern for the safety of dimethicone, the levels used in skincare are safe for use.

26
What it does:
Community Rating: Disliked

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
27
What it does: Emulsion Stabilising, Gel Forming
Community Rating: Disliked

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

Carbomer is commonly found in many types of cosmetics products. It is found to be safe in concentrations up to 15%. However, a high amount of carbomer can cause pilling or balling up of products. Most products contain 1% of less of carbomer.

28
What it does: Cleansing, Emulsifying
Community Rating: Very Disliked

Ceteareth-20 is an emulsifier and cleansing agent. It is derived from cetearyl alcohol, a fatty alcohol.

As an emulsifier, Ceteareth-20 prevents oil and water from separating. It is also a surfactant. Surfactants help gather oil, pollution, and dirt to be washed away.

29
What it does: Emollient, Skin Conditioning, Solvent
Community Rating: Disliked

Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.

D5 is considered lightweight and volatile. Volatile means it evaporates quickly after application. Once evaporated, D5 leaves a thin barrier that helps keep skin hydrated.

D5 is an emollient. Emollients help soften the skin and prevent water loss. Silicones create a silky texture in products. D5 helps other ingredients become more spreadable.

Studies show D5 is safe to use in skincare products. We recommend speaking with a skincare professional if you have concerns.

Learn more about Cyclopentasiloxane
30
What it does: Emollient, Humectant, Skin Conditioning
Community Rating: Liked

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
31
What it does: Emollient, Skin Conditioning, Solvent
Community Rating: Disliked

Cyclohexasiloxane is a type of silicone more commonly known as D6. It is an emollient and solvent.

Cyclohexasiloxane is used to evenly distribute ingredients throughout the product. When applied to the skin, Cyclohexasiloxane evaporates and leaves behind a silky feel.

As an emollient, it can help the skin feel soft and hydrated. It is also used to reduce frizz in hair products.

Learn more about Cyclohexasiloxane
32
What it does: Emulsifying
Community Rating: Very Disliked

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.

Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.

The lauric acid used to create Polysorbate 20 is often derived from coconuts.

Polysorbate 20 may not be fungal acne safe.

Learn more about Polysorbate 20
33
What it does: Emulsifying, Masking, Perfuming, Skin Conditioning
Community Rating: Very Disliked

Zea Mays Oil is refined oil. It is created from the process of wet milling corn, or zea mays. Zea Mays Oil is fragrance ingredient, hair conditioning agent, occlusive skin conditioning agent, surfactant, and emulsifying agent.

It is composed of several fatty acids, including myristic, palmitic, stearic, oleic, and linoleic.

34
What it does: Preservative
Community Rating: Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

35
What it does: Preservative
Community Rating: Very Disliked

Sorbic Acid is a preservative. It is the most commonly used food preservative in the world.

Sorbic Acid is a natural antibiotic and highly effective at preventing the growth of fungus. It is less effective against bacteria.

Potassium Sorbate, another commonly-used preservative, is the potassium salt of Sorbic Acid.

Sorbic Acid may worsen eczema. We recommend speaking with a professional if you have any concerns.

Potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

Learn more about Sorbic Acid
Embed Ingredients

Here's what our community thinks of the 35 ingredients in this product ✨

37% are loved or liked
9% have mixed ratings
46% are disliked or very disliked
9% have no rating yet

When to use

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