Versus

Paula's Choice Probiotic Nutrient Moisturizer Versus Neogen Probiotics Relief Cream

General Moisturizer
General Moisturizer
American Brand United States
Korean Brand South Korea

Updated on July 18, 2024

Overview

What they are

These products are both reef safe general moisturizers. They have a total of 23 ingredients in common

Cool Features

They both contain AHA, ceramides, niacinamide, peptides, Vitamin C and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, common allergens, parabens or sulfates

What's Inside

They both contain oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Probiotic Nutrient Moisturizer

Water

Skin Conditioning

Isoamyl Laurate

Emollient
Not safe for Fungal Acne Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Sodium Polyacrylate Starch

Absorbent

Cetyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Lauroyl Lysine

Skin Conditioning

Lactobacillus/Rye Flour Ferment

Skin Conditioning

Lactobacillus Ferment

Skin Conditioning

Bifida Ferment Lysate

Skin Conditioning
Helps hydrate Dry Skin Icon

Glucomannan

Skin Conditioning

Saccharomyces Lysate

Skin Conditioning

Leuconostoc/Radish Root Ferment Filtrate

Antimicrobial
Not safe for Fungal Acne Icon

Glycine Soja Seed Extract

Skin Conditioning

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Tetrahexyldecyl Ascorbate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Acetyl Hexapeptide-1

Skin Conditioning
Peptide Icon

Palmitoyl Dipeptide-10

Skin Conditioning
Peptide Icon

Ceramide Ng

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Orbignya Oleifera Seed Oil

Emollient
1 / 0 Oil IconNot safe for Fungal Acne Icon

Palmitoyl Proline

Skin Conditioning

Glycine

Buffering
Helps hydrate Dry Skin Icon

Serine

Masking

Threonine

Alanine

Masking

Valine

Masking

Arginine

Masking
Good for Scar Healing IconNot safe for Fungal Acne Icon

Proline

Skin Conditioning

Lysine Hcl

Skin Conditioning
Helps hydrate Dry Skin Icon

Rubus Idaeus Fruit Extract

Astringent

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Adenosine

Skin Conditioning
Good for Minimizing Pores IconGood for Scar Healing Icon

Lecithin

Emollient

Phytic Acid

AHA IconGood for Oily Skin IconHelps brighten skin IconMay worsen Rosacea Icon

Yeast Extract

Skin Conditioning
Not safe for Fungal Acne Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Sodium PCA

Humectant
0 / 0

Sodium Lactate

Buffering

PCA

Humectant

Magnesium Palmitoyl Glutamate

Skin Conditioning

Sodium Palmitoyl Sarcosinate

Cleansing

Isopropyl Palmitate

Emollient
3-4 / 1 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Glutamic Acid

Humectant

Betaine

Humectant
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Hydroxyacetophenone

Antioxidant
Antioxidant Icon

Sodium Acrylates Copolymer

Ceteth-20

Cleansing

Steareth-20

Cleansing
2 / 1

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

PEG-75 Stearate

Not safe for Fungal Acne Icon

Caprylyl Glycol

Emollient

Propylene Glycol

Humectant
0 / 0 Helps hydrate Dry Skin IconMay worsen Eczema IconMay worsen Rosacea Icon

1,2-Hexanediol

Skin Conditioning

Phenoxyethanol

Preservative
Preservative Icon

Ethylhexylglycerin

Skin Conditioning
Probiotics Relief Cream

Water

Skin Conditioning

Lactobacillus Ferment Lysate 14.3%

Skin Conditioning
Not safe for Fungal Acne Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Propanediol

Solvent

Isopentyldiol

Humectant

Dimethicone

Emollient
1 / 0 Silicon Icon

Cyclopentasiloxane

Emollient
Silicon Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Hydrogenated Poly(C6-14 Olefin)

Emollient

Cyclohexasiloxane

Emollient
Silicon Icon

1,2-Hexanediol

Skin Conditioning

PEG-240/Hdi Copolymer Bis-Decyltetradeceth-20 Ether

Stabilising

Butyrospermum Parkii Butter

Skin Conditioning
Helps hydrate Dry Skin IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Polyglyceryl-10 Myristate

Skin Conditioning
Not safe for Fungal Acne Icon

Polyglyceryl-2 Stearate

Emulsifying
Not safe for Fungal Acne Icon

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Stearyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Ethylhexylglycerin

Skin Conditioning

Adenosine

Skin Conditioning
Good for Minimizing Pores IconGood for Scar Healing Icon

Betaine

Humectant
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots Icon

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Trehalose

Humectant

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Sodium PCA

Humectant
0 / 0

Bifida Ferment Lysate

Skin Conditioning
Helps hydrate Dry Skin Icon

Sodium Lactate

Buffering

Gossypium Herbaceum Extract

Skin Conditioning

Arginine

Masking
Good for Scar Healing IconNot safe for Fungal Acne Icon

Aspartic Acid

Masking

PCA

Humectant

Streptococcus Thermophilus Ferment

Humectant

Caprylic/Capric Triglyceride

Masking

Glycine

Buffering
Helps hydrate Dry Skin Icon

Alanine

Masking

Lecithin

Emollient

Royal Jelly Extract

Skin Conditioning
Good for Scar Healing Icon

Milk Extract

Skin Conditioning

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Propolis Extract

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing IconHelps fight Acne Icon

Hydrolyzed Collagen

Emollient
Helps hydrate Dry Skin IconHelps with Anti-Aging Icon

Lactose

Humectant

Artemisia Capillaris Extract

Simmondsia Chinensis Seed Oil

Emollient
0-2 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Serine

Masking

Valine

Masking

Isoleucine

Skin Conditioning

Threonine

Proline

Skin Conditioning

Phenylalanine

Masking

Histidine

Humectant

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Lupinus Albus Seed Extract

Skin Conditioning

Sodium Ascorbyl Phosphate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Phospholipids

Skin Conditioning

Phytosphingosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Copper Tripeptide-1

Skin Conditioning
Peptide IconGood for Skin Texture IconHelps with Anti-Aging Icon

Ceramide 3

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Lactic Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Madecassoside

Antioxidant
Antioxidant IconHelps reduce irritation IconHelps with Anti-Aging Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Tripeptide-1

Skin Conditioning
Peptide IconHelps with Anti-Aging Icon

Palmitoyl Tripeptide-1

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Tripeptide-2

Skin Conditioning
Peptide Icon

Hexapeptide-11

Skin Conditioning
Peptide Icon

Phytosterols

Skin Conditioning

Dunaliella Salina Extract

Skin Conditioning

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps with Anti-Aging Icon

Palmitoyl Tetrapeptide-7

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Palmitoyl Pentapeptide-4

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Hexapeptide-9

Skin Conditioning
Peptide Icon

Nonapeptide-1

Skin Conditioning
Peptide Icon

Disodium EDTA

Parfum

Masking
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.
  • It has mild preservative properties.

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Skin Conditioning

Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

Having a healthy microbiome helps protect our skin against infection. It also helps our skin stay hydrated and healthy.

Studies also show this ingredient to be a promising soothing ingredient for sensitive skin.

Learn more about Bifida Ferment Lysate
Buffering, Skin Conditioning

This ingredient is an amino acid that helps build proteins and moisturizes skin. It is already present in our skin as our bodies produce them naturally.

Glycine already plays a role in helping keep our skin moisturized as amino acids transport moisture throughout our skin.

As collagen is made up of glycine and other amino acids, it is believed glycine may help our skin produce more collagen.

Learn more about Glycine
Masking, Skin Conditioning

Serine is an amino acid naturally found in our body. Our bodies use amino acids to create protein.

Amino-acids help give keep our skin hydrated. They play an important role in the skin barrier, which keeps the skin plump and firm.

Serine is a non-essential amino acid, meaning we don't need to obtain it from eating foods.

Learn more about Serine

Threonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.

Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.

Masking, Skin Conditioning

Alanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.

Masking, Skin Conditioning

Valine is an essential amino acid. It is used by our bodies for tissue repair and muscle growth.

An essential amino acid is one in which our bodies cannot naturally produce so we must get them through diet. Foods such as eggs, dairy, red meat, and fish contain valine.

This ingredient can either be derived from an animal product or be synthetically created.

Learn more about Valine
Masking, Skin Conditioning

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

As a cosmetic ingredient, Arginine has antioxidant properties and can also help repair damaged skin. This ingredient is derived either synthetically or from animals.

Arginine isn't fungal acne safe when used in the presence of other lipids (fats, fatty acids, oils, esters, etc). Oils and fats occur naturally within the skin, so take caution when using Arginine if you're prone to fungal acne.

Learn more about Arginine
Skin Conditioning

Proline is an amino-acid. It helps moisturize the skin and plays an important role in creating proteins.

Our skin uses proline as one of the building blocks for producing collagen.

In medicine, proline is used as an osmoprotectant. This means it helps prevent oxidative degradation in other drugs.

Our bodies are able to produce proline naturally, but certain conditions may inhibit this production. In that case, proline can be obtained from eating egg whites, soy protein, dairy products, asparagus, mushrooms, and seaweed.

Learn more about Proline
Smoothing

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine
Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.

This ingredient has emollient and emulsifying properties.

As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.

As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.

This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.

Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.

We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.

Learn more about Lecithin
Antioxidant, Masking, Skin Conditioning

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol
Humectant, Skin Conditioning

Sodium PCA is the sodium salt of pyroglutamic acid. It is naturally occurring in our skin's natural moisturizing factors where it works to maintain hydration.

The PCA stands for pyrrolidone carboxylic acid, a natural amino acid derivative.

This ingredient has skin conditioning, anti-inflammatory, and humectant properties. Humectants help hydrate your skin by drawing moisture from the air. This helps keep your skin moisturized.

Learn more about Sodium PCA
Buffering, Humectant

Sodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and sometimes used to adjust the pH of a product.

This ingredient is part of our skin's NMF, or natural moisturizing factor. Our NMF is essential for the hydration of our top skin layers and plasticity of skin. NMF also influences our skin's natural acid mantle and pH, which protects our skin from harmful bacteria.

High percentages of Sodium Lactate can have an exfoliating effect.

Fun fact: Sodium Lactate is produced from fermented sugar.

Learn more about Sodium Lactate
PCA
Humectant, Moisturising

PCA is derived from amino acids and is naturally found in our skin's barrier.

As a humectant, PCA helps draw and hold moisture to the skin. Studies show it is effective at helping the skin stay hydrated long-term.

Humectant, Skin Conditioning

Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.

This ingredient is best for improving hydration and soothing irritated skin. Studies also show it helps even out skin tone.

Fun fact: Betaine is naturally created in the skin and body. The kind found within cosmetic products can be either plant-derived or synthetic.

Learn more about Betaine
Emollient, Emulsifying

Glyceryl Stearate is a mix of glycerin and stearic acid.

It is used to stabilize the mixing of water and oil ingredients. By preventing these ingredients from separating, it can help elongate shelf life. It can also help thicken the product's texture.

As an emollient, it helps soften skin and supports barrier-replenishing ingredients.

In cosmetics, Glyceryl Stearate is often made from vegetable oils or synthetically produced.

This ingredient may not be fungal-acne safe

Fun fact: The human body also creates Glyceryl Stearate naturally.

Learn more about Glyceryl Stearate
Emulsifying

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.

Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.

The lauric acid used to create Polysorbate 20 is often derived from coconuts.

Polysorbate 20 may not be fungal acne safe.

Learn more about Polysorbate 20
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

When to use

16 Routines
50% use in am
50% use in pm
94% use every day

Reviews

Here's what our community thinks

Paula's Choice Probiotic Nutrient Moisturizer 56 ingredients

4.0 /5
from 1 rating
sameteamdwight's avatar

sameteamdwight

4 years ago
Review

On the Fence
I'm a little on the fence about this product. It goes on smoothly although it has a gooey, sticky texture and it doesn't interfere with any of the serums or oils I put on before it. It smells like wet cardboard (although my toddler told me it smelled like donut so I guess YMMV) but it does dissipate soon enough. It has a lot of sexy ingredients that made me fall for it in the first Show more

Neogen Probiotics Relief Cream 80 ingredients

5.0 /5
from 1 rating
SurayaIzhar_84's avatar

SurayaIzhar_84

1 year ago
Review

My holy grail moisturiser
I have always wanted a cream type of moisturiser but it’s hard to find due to their clogging ingredients. But this , it doesn’t break me out, super moisturising. I love this product so much 🥹💖 Wont ever change😄