Numbuzin No.9 NAD Bio Lifting-Sil Full Face Mask Versus Numbuzin 9+ NMN Bio Liftingsil Essence
Updated on March 17, 2025
Overview
What they are
These products are both cruelty-free and reef safe . They have a total of 60 ingredients in common
Cool Features
They both contain niacinamide and peptides
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, common allergens, fragrances, parabens or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Numbuzin No.9 NAD Bio Lifting-Sil Full Face Mask 120 ingredients
Numbuzin 9+ NMN Bio Liftingsil Essence 121 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
Numbuzin No.9 NAD Bio Lifting-Sil Full Face Mask 120 ingredients
Numbuzin 9+ NMN Bio Liftingsil Essence 121 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Acetyl Dipeptide-1 Cetyl Ester is a peptide composed of amino acids arginine and tyrosine.
This peptide is considered a neurotransmitter peptide, meaning it has pain-relieving and relaxing properties. It has the ability to calm skin irritation from external factors such as chemical stinging or heat.
Neurotransmitter peptides are also often called "botox in a bottle". This is because these peptides have the ability to relax the muscles.
Though relaxing the muscles can prevent expression lines (as we have seen in botox), the studies do not show these peptides to be a botox replacement. The effects of this muscle relaxation is also short-term, as opposed to longer-term results from botox.
Learn more about Acetyl Dipeptide-1 Cetyl EsterAcetyl Hexapeptide-8, commonly known as Argireline, is a popular peptide in skincare. It’s often referred to as a “Botox-like” ingredient because it helps reduce muscle movement.
By relaxing these micro-movements, Argireline may help minimize the appearance of fine lines and wrinkles. That said, it’s not as powerful as Botox, and research on its long-term effectiveness is still limited.
Beyond smoothing, Argireline may also support collagen production. Collagen is the protein that helps keep your skin firm, bouncy, and well-hydrated by strengthening the skin barrier.
So while Argireline isn’t a miracle fix, it can be a helpful addition to a routine focused on both prevention and skin health.
Read more about other common types of peptides here:
Learn more about Acetyl Hexapeptide-8Acetyl Octapeptide-3 is a synthetic peptide also commonly known as SNAP-8. It is a lab-made peptide often marketed as a gentler, topical alternative to Botox.
It works by mimicking part of a protein involved in muscle contractions, which may help relax facial tension and reduce the appearance of fine lines (mostly around the eyes and forehead).
It’s considered a “next-gen” version of Argireline (Acetyl Hexapeptide-8), an older peptide with more research behind it that also supports collagen production.
SNAP-8 showed slightly better results than Argireline in one small manufacturer-funded study, but there’s limited independent research. Plus, most tests use concentrations higher than what’s typically found in skincare products.
This ingredient might offer a subtle smoothing effect but it won't don’t deliver the dramatic results of actual Botox injections.
Think of it more like a supporting actor in your skincare lineup.
Learn more about Acetyl Octapeptide-3This peptide is more commonly known as Thymulen 4 BG.
It is derived from a youth hormone called thymopoietin. Thymopoietin helps regulate the immune system and decreases naturally with age.
According to the manufacturer, this peptide boosts the skin's immune defenses and regenerates the outer layers of skin.
Learn more about Acetyl Tetrapeptide-2This biometic peptide is designed to support hair growth.
According to a manufacturer, it stimulates hair growth by:
The manufacturer has found combining this ingredient with red clover extract (Capixyl) boosted benefits. Not only does it enforce the scalp's extracellular matrix, it also inhibits the enzyme that creates DHT, a hormone that leads to hair loss.
While this ingredient is promising, more research is still needed to confirm its full effectiveness.
Learn more about Acetyl Tetrapeptide-3Acetyl Tetrapeptide-5 is a peptide that goes by another name, eyeseryl, due to claims that it can help reduce eye puffiness.
The manufacturer claims this ingredient reduces eye puffiness by:
An in-vivo study from the manufacturer found 95% of volunteers saw eye bag improvement by the end of the study.
Eye puffiness is caused by two major factors: fluid retention and fat.
Those with fluid retention may see improvement from using this ingredient. However, those with eye fat will need surgical intervention in order to get rid of puffiness.
Learn more about Acetyl Tetrapeptide-5Acetyl Tetrapeptide-9 is a signal peptide. Signal peptides tell your skin to create collagen or start tissue repair.
This peptide plays a role in key skin components such as collagen, lumican, and glycosaminoglycans (GAGs). Lumican is used in collagen organization and regulation, while GAGs are a component that holds water in our skin.
The manufacturer claims this ingredient is effective at firming the skin and enhancing skin hydration.
Learn more about Acetyl Tetrapeptide-9Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.
Studies have found adenosine may also help with wound healing.
In skincare products, Adenosine is usually derived from yeast.
Learn more about AdenosineAdenosine Triphosphate is from the hydrolysis of nucleic acids in yeast. It comes from adenosine, one of the four building blocks for RNA.
Our bodies use Adenosine Triphosphate for energy at the cellular level.
It is an antioxidant. Antioxidants help fight off damage from free-radical molecules.
Adenosine Triphosphate may help with reducing irritation.
Learn more about Adenosine TriphosphateAmmonium Acryloyldimethyltaurate/Vp Copolymer (let's call it AAVC for short) is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.
AAVC is able to increase the consistency and viscosity of products due to its large molecule size. It also prevents ingredients from separating.
Astaxanthin is a carotene pigment and red pigment. It is a promising antioxidant with a ton of skin benefits.
This antioxidant has great anti-aging benefits by blocking the following:
Astaxanthin is also great at soothing skin due to its ability to block molecules that signal inflammation. It is currently being studied for preventing chronic inflammatory diseases.
Plus, a study from 2012 found Astaxanthin in liposomes protected mouse skin from UV-damage.
Fun fact: Astaxanthin is responsible for giving salmon a pink color.
Learn more about AstaxanthinBiotinoyl Tripeptide-1 is a peptide.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCarbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.
A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.
Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.
It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.
While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.
Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.
Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.
Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.
For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.
After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.
While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.
Read more about other common types of peptides here:
Learn more about Copper Tripeptide-1Dextran is a sugar (polysaccharide) with skin hydrating properties.
Fun fact: Louis Pasteur first discovered this ingredient as a microbial product in wine.
This small molecule peptide has similar benefits to Argireline, the "botox" peptide.
According to the manufacturer, this peptide mimics snake venom to freeze muscles. This prevents muscle movement and contractions to prohibit the formation of fine lines and wrinkles.
While this seems promising, research is lacking in proving this ingredient to be as effective as botox.
Learn more about Dipeptide Diaminobutyroyl Benzylamide DiacetateDipeptide-4 is a peptide.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Glutathione is an antioxidant naturally found in our bodies. It is made up of three amino acids: glycine, cysteine, and glutamic acid.
As an antioxidant, it prevents oxidative damage to parts of our cell.
While glutathione is said to help with fading dark spots, the results from research are inconclusive. Further studies are needed. With that said, gluthatione has been shown to protect our skin from UV-B induced damage.
This ingredient is naturally occurring in plants, animals, fungi, and some bacteria.
Learn more about GlutathioneGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinThis synthetic peptide is known as a signal peptide. Signal peptides tell your skin to create more collagen, elastin and protein.
Hexapeptide-11 is composed of several amino acids, including alanine.
Hexapeptide-9 is a peptide.
Hydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.
This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
We don't have a description for Hydrogenated Poly(C6-14 Olefin) yet.
Methylpropanediol is a synthetic solvent and humectant.
As a solvent, it helps dissolve other ingredients, helping to evenly distribute ingredients throughout the product. This ingredient has also been shown to have antimicrobial properties which makes it a preservative booster.
Methylpropanediol is able to add a bit of moisture to the skin. It also helps other ingredients be better absorbed into the skin, such as salicylic acid.
Learn more about MethylpropanediolNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideWe don't have a description for Nicotinamide Adenine Dinucleotide yet.
Nicotinoyl Tripeptide-1 is an antioxidant and is a peptide.
Nonapeptide-1 is created from amino acids including arginine and lysine.
It has antioxidant and antimicrobial properties.
Emerging studies show Nonapeptide-1 to help with reducing pigmentation and brightening the skin. It has shown to prevent the activation of tyrosinase, an enzyme in the skin that begins the process of melanin creation. Melanin is responsible for giving skin a tan or dark spots.
Learn more about Nonapeptide-1Palmitoyl Hexapeptide-12 is a synthetic peptide made with glycine, histidine, lysine, and palmitic acid.
The sequence of this peptide matches that of elastin, a key protein that plays a role in how firm our skin is.
Due to its palmitic acid base, this ingredient may not be fungal-acne safe.
Learn more about Palmitoyl Hexapeptide-12You might know this ingredients as Matrixyl, a famous peptide.
Peptides are building blocks for protein. Palmitoyl Pentapeptide-4 consists of five amino acids. These amino acids include: 2 lysines, 2 threonines, and serine
This ingredients tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Thus, Matrixyl may help improve the look of wrinkles.
Read more about other common types of peptides here:
Learn more about Palmitoyl Pentapeptide-4Palmitoyl Tetrapeptide-7 is a lab-made peptide with anti-inflammatory and skin-repairing benefits. It's made up of four amino acids (glycine, glutamine, proline, and arginine) and palmitic acid (which helps it penetrate skin more effectively).
This ingredient helps reduce inflammation by limiting the production of interleukin-6 (IL-6), a chemical that triggers inflammatory responses, particularly after UV exposure.
Less inflammation = slower collagen breakdown and a longer-lasting, youthful appearance.
Palmitoyl Tetrapeptide-7 also stimulates collagen production and supports a healthier skin barrier.
Over time, this can improve skin firmness, hydration, and reduce the appearance of fine lines. It’s commonly paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.
This ingredient has been shown to be effective and safe in cosmetic use and you'll typically find it in small amounts (less than 0.01%).
Due to its palmitic acid base, it may not be safe for Malassezia folliculitis.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tetrapeptide-7Palmitoyl Tripeptide-1 is also known as pal-GHK. It is made up of 3 amino acids and palmitic acid, a fatty acid that helps it absorb into skin more easily.
This peptide is as a signal peptide, meaning it tells the skin to produce more collagen. Collagen is the key protein that helps form the skin's structure and keep it plump, firm, and hydrated.
By boosting collagen production, this ingredient supports a stronger skin barrier and helps reduce the appearance of wrinkles.
You'll most likely see this ingredient paired with Palmitoyl Tetrapeptide-7 in the well-known Matrixyl 3000 complex. While results from in-house testing should be viewed cautiously, this peptide duo is among the most studied and widely used in modern skincare.
Due to its palmitic acid base, this ingredient may not be safe for Malassezia folliculitis.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tripeptide-1This synthetic peptide is created from lysine, valine, and palmitic acid.
According to the manufacturer, in-vitro studies show tissue growth and collagen synthesis. Another in-vivo study found 60 volunteers saw a significant reduction in wrinkles after 84 days.
Due to its palmitic acid base, this peptide may not be fungal-acne safe.
Learn more about Palmitoyl Tripeptide-5This synthetic peptide is created from palmitic acid, arginine, histidine, and phenylalanine.
According to the manufacturer, this peptide is great at soothing skin inflammation.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolPolyglyceryl-3 Methylglucose Distearate is created from the diester of stearic acid and the condensation product of methylglucose and Polyglycerin-3.
As an emulsifier, it is used to bind ingredients together. Many ingredients, such as oils and water, separate naturally. Emulsifiers prevent them from separating to ensure even consistency in texture.
One of the manufacturer for this ingredient states it is vegetable-based. It is also claimed to be stable at both high and low temperatures.
This ingredient may not be safe for fungal acne. We recommend speaking with a professional if you have any concerns.
Learn more about Polyglyceryl-3 Methylglucose DistearatePropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolResveratrol is a famous emerging antioxidant. It is a good alternative for sensitive skin types who cannot tolerate retinoids.
This antioxidant is most famous for it's anti-aging benefits. Studies show it combats the signs of aging by:
Besides anti-aging, this ingredient also helps with skin brightening and soothing.
The most effective forms of resveratrol are isobutyrate and butyrate. These have the strongest effect on increasing A1 collagen and reducing inflammation.
A note on it being a retinoid alternative:
Despite it's amazing skin benefits, it is not a replacement for retinoids. However, it is recommended for people with sensitive skin or intolerance to retinoids.
Resveratrol is naturally found in grapes, peanuts, and berries.
Learn more about ResveratrolWe don't have a description for Saccharomyces/Copper Ferment yet.
We don't have a description for Saccharomyces/Iron Ferment yet.
We don't have a description for Saccharomyces/Magnesium Ferment yet.
We don't have a description for Saccharomyces/Silicon Ferment yet.
We don't have a description for Saccharomyces/Zinc Ferment yet.
Sh-Decapeptide-7 is an antioxidant and is a peptide.
Sh-Octapeptide-4 is an antioxidant and is a peptide.
sh-Oligopeptide-1 is a peptide found naturally in our bodies. Peptides are the building blocks for collagen and elastin in our skin.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
Studies find EGF help with:
In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.
According to Dr. Zoe Draelos, growth factors have some drawbacks:
There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-1This peptide has similar properties to Sh-Oligopeptide-1.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
There is also controversy surrounding EGF. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-2Sh-Polypeptide-1 is a signal peptide that tells our cells to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.
It is important to note this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
Peptides are amino acids naturally found in your skin. These amino acids make up many proteins your skin uses. Collagen is made up of peptides. Collagen is responsible for keeping your skin plump and youthful.
As you age, your body naturally produces less collagen. Since peptides are the building blocks of collagen, it may have anti-aging effects.
Sh-Polypeptide-3 is a peptide.
Sodium Polyacrylate is the sodium salt of polyacrylic acid. It is used as an absorber, emollient, and stabilizer.
This ingredient is a super-absorbent polymer - meaning it can absorb 100 to 1000 times its mass in water. As an emollient, Sodium Polyacrylate helps soften and soothe skin. Emollients work by creating a barrier to trap moisture in. This helps keep your skin hydrated.
Thioctic Acid is an enzyme and antioxidant. A more common name for this is Alpha Lipoic Acid.
Alpha Lipoic Acid can be naturally found in the mitochondria of every cell.
Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells. The antioxidants in Alpha Lipoic Acid have been shown to fight damage from cigarette smoke.
Studies also show Alpha Lipoic Acid plays a role in wound healing.
Thioctic Acid will break down when exposed to sunlight.
Many foods contain thioctic acid, including tomato, brussel sprouts, spinach, and broccoli.
Learn more about Thioctic AcidThis extract comes from the flower more commonly known as red clover.
Tripeptide-1 is a peptide. It can help to reduce the effects of aging.
Ubiquinone (Coenzyme Q10) is a molecule already found in our bodies. It is a potent antioxidant and skin-soothing ingredient.
Aging and environmental exposure diminishes our skin's natural ubiquinone levels. This is much like our natural collagen and elastin.
The good news is: studies show applying this ingredient topically replenishes ubiquinone levels in our skin. This also comes with a ton of skin benefits. These benefits include:
Ubiquinone is considered a large molecule and cannot be absorbed into the lower layers of skin. This is why it is believed to be such an effective antioxidant: it protects our skin in the upper layers and prevents damage in the deeper layers.
When used in sunscreen, ubiquinone is shown to increase ingredient stability, increase SPF factor, and add to infrared protection.
Fun fact: ubiquinone is fat-soluble.
Learn more about UbiquinoneWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumIngredient Ratings
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