Nu Skin ageLOC® Radiant Day SPF 22 Versus Estée Lauder DayWear Advanced Multi-Protection Anti-Oxidant Creme SPF 15
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Butyl Methoxydibenzoylmethane 3%
UV AbsorberHomosalate 5%
Skin ConditioningEthylhexyl Salicylate 4%
UV AbsorberOctocrylene 2%
UV AbsorberWater
Skin ConditioningGlycerin
HumectantCyclopentasiloxane
EmollientAcrylamide/Sodium Acryloyldimethyltaurate Copolymer
Emulsion StabilisingGlyceryl Stearate
EmollientPEG-100 Stearate
SurfactantDimethicone
EmollientCyclohexasiloxane
EmollientDimethicone/Vinyl Dimethicone Crosspolymer
Skin ConditioningCetyl Alcohol
EmollientMethyl Gluceth-10
EmulsifyingSteareth-2
EmulsifyingSteareth-21
CleansingIsohexadecane
EmollientNylon-12
Hydrolyzed Jojoba Esters
Skin ConditioningJojoba Esters
EmollientBambusa Vulgaris Leaf/Stem Extract
HumectantGlucosamine Hcl
Pisum Sativum Extract
Skin ConditioningHexapeptide-2
BleachingNarcissus Tazetta Bulb Extract
AstringentSalicin
Skin ConditioningSchisandra Chinensis Fruit Extract
Skin ConditioningButyrospermum Parkii Butter
Skin ConditioningPolysorbate 80
EmulsifyingTitanium Dioxide
Cosmetic ColorantButylene Glycol
HumectantCitric Acid
BufferingDisodium EDTA
Parfum
MaskingChlorphenesin
AntimicrobialPhenoxyethanol
PreservativeCaprylyl Glycol
Emollient1,2-Hexanediol
Skin ConditioningTropolone
Skin ConditioningButyl Methoxydibenzoylmethane 3%, Homosalate 5%, Ethylhexyl Salicylate 4%, Octocrylene 2%, Water, Glycerin, Cyclopentasiloxane, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Glyceryl Stearate, PEG-100 Stearate, Dimethicone, Cyclohexasiloxane, Dimethicone/Vinyl Dimethicone Crosspolymer, Cetyl Alcohol, Methyl Gluceth-10, Steareth-2, Steareth-21, Isohexadecane, Nylon-12, Hydrolyzed Jojoba Esters, Jojoba Esters, Bambusa Vulgaris Leaf/Stem Extract, Glucosamine Hcl, Pisum Sativum Extract, Hexapeptide-2, Narcissus Tazetta Bulb Extract, Salicin, Schisandra Chinensis Fruit Extract, Butyrospermum Parkii Butter, Polysorbate 80, Titanium Dioxide, Butylene Glycol, Citric Acid, Disodium EDTA, Parfum, Chlorphenesin, Phenoxyethanol, Caprylyl Glycol, 1,2-Hexanediol, Tropolone
Ethylhexyl Salicylate 5%
UV AbsorberButyl Methoxydibenzoylmethane 3%
UV AbsorberHomosalate 2%
Skin ConditioningWater
Skin ConditioningButyloctyl Salicylate
Skin ConditioningPolyester-8
Skin ConditioningPetrolatum
EmollientButylene Glycol
HumectantCetyl Ricinoleate
EmollientOctyldodecyl Myristate
EmollientSteareth-21
CleansingSteareth-2
EmulsifyingCaprylic/Capric/Myristic/Stearic Triglyceride
EmollientDi-C12-15 Alkyl Fumarate
EmollientDimethicone
EmollientPsidium Guajava Fruit Extract
AstringentGentiana Lutea Root Extract
Skin ConditioningPolygonum Cuspidatum Root Extract
AntioxidantHordeum Vulgare Extract
EmollientLaminaria Ochroleuca Extract
Skin ConditioningTriticum Vulgare Germ Extract
Skin ConditioningFumaria Officinalis Flower/Leaf/Stem Extract
Skin ConditioningCitrus Medica Limonum Fruit Extract
Skin ConditioningHydrolyzed Rice Bran Extract
Skin ConditioningHydrolyzed Rice Extract
Skin ConditioningArtemia Extract
Skin ConditioningRosmarinus Officinalis Leaf Extract
AntimicrobialVitis Vinifera Seed Extract
AntimicrobialStearyl Alcohol
EmollientButyrospermum Parkii Butter
Skin ConditioningThermus Thermophillus Ferment
Skin ConditioningSorbitan Olivate
EmulsifyingCaffeine
Skin ConditioningPentylene Glycol
Skin ConditioningLauryl PEG-9 Polydimethylsiloxyethyl Dimethicone
Skin ConditioningBehenyl Alcohol
EmollientPantethine
EmollientTriacontanyl Pvp
HumectantAcrylic Acid/Vp Crosspolymer
SurfactantEthylhexylglycerin
Skin ConditioningGlycerin
HumectantLinoleic Acid
CleansingPolyquaternium-51
Skin ConditioningCholesterol
EmollientCetearyl Olivate
Squalane
EmollientSodium PCA
HumectantUrea
BufferingCaprylic/Capric Triglyceride
MaskingTocopheryl Acetate
AntioxidantTetrahexyldecyl Ascorbate
AntioxidantCitric Acid
BufferingSodium Hyaluronate
HumectantErgothioneine
AntioxidantGlycyrrhetinic Acid
Skin ConditioningTrehalose
HumectantLecithin
EmollientHydrogenated Lecithin
EmulsifyingPalmitoyl Hydroxypropyltrimonium Amylopectin/Glycerin Crosspolymer
Skin ConditioningCyclodextrin
AbsorbentNordihydroguaiaretic Acid
AntioxidantAscorbyl Tocopheryl Maleate
AntioxidantSodium Hydroxide
BufferingParfum
MaskingFumaric Acid
BufferingPentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
AntioxidantEthylbisiminomethylguaiacol Manganese Chloride
AntioxidantDisodium EDTA
BHT
AntioxidantPhenoxyethanol
PreservativeBenzyl Salicylate
PerfumingHydroxyisohexyl 3-Cyclohexene Carboxaldehyde
MaskingButylphenyl Methylpropional
PerfumingLinalool
PerfumingMica
Cosmetic ColorantCI 19140
Cosmetic ColorantCI 42090
Cosmetic ColorantCI 77289
Cosmetic ColorantEthylhexyl Salicylate 5%, Butyl Methoxydibenzoylmethane 3%, Homosalate 2%, Water, Butyloctyl Salicylate, Polyester-8, Petrolatum, Butylene Glycol, Cetyl Ricinoleate, Octyldodecyl Myristate, Steareth-21, Steareth-2, Caprylic/Capric/Myristic/Stearic Triglyceride, Di-C12-15 Alkyl Fumarate, Dimethicone, Psidium Guajava Fruit Extract, Gentiana Lutea Root Extract, Polygonum Cuspidatum Root Extract, Hordeum Vulgare Extract, Laminaria Ochroleuca Extract, Triticum Vulgare Germ Extract, Fumaria Officinalis Flower/Leaf/Stem Extract, Citrus Medica Limonum Fruit Extract, Hydrolyzed Rice Bran Extract, Hydrolyzed Rice Extract, Artemia Extract, Rosmarinus Officinalis Leaf Extract, Vitis Vinifera Seed Extract, Stearyl Alcohol, Butyrospermum Parkii Butter, Thermus Thermophillus Ferment, Sorbitan Olivate, Caffeine, Pentylene Glycol, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Behenyl Alcohol, Pantethine, Triacontanyl Pvp, Acrylic Acid/Vp Crosspolymer, Ethylhexylglycerin, Glycerin, Linoleic Acid, Polyquaternium-51, Cholesterol, Cetearyl Olivate, Squalane, Sodium PCA, Urea, Caprylic/Capric Triglyceride, Tocopheryl Acetate, Tetrahexyldecyl Ascorbate, Citric Acid, Sodium Hyaluronate, Ergothioneine, Glycyrrhetinic Acid, Trehalose, Lecithin, Hydrogenated Lecithin, Palmitoyl Hydroxypropyltrimonium Amylopectin/Glycerin Crosspolymer, Cyclodextrin, Nordihydroguaiaretic Acid, Ascorbyl Tocopheryl Maleate, Sodium Hydroxide, Parfum, Fumaric Acid, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Ethylbisiminomethylguaiacol Manganese Chloride, Disodium EDTA, BHT, Phenoxyethanol, Benzyl Salicylate, Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde, Butylphenyl Methylpropional, Linalool, Mica, CI 19140, CI 42090, CI 77289
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Also known as Avobenzone, this ingredient is an oil-soluble used to absorb the full spectrum of UVA rays (peak 357 nm).
It's one of the most effective UVA filters available but has a major caveat of photostability: avobenzone is susceptible to photodegradation.
This means it can lose efficacy when exposed to sunlight without the help of a stabilizing agent.
Studies show antioxidants (like vitamin E or vitamin C) and some UV filters (like octocrylene and Tinosorb S) can meaningfully improve its stability in a formulation.
The maximum allowable concentration according to regulation is 3% in the US + Canada, and 5% in the EU, Australia, China, Korea, and ASEAN countries.
It has a well-support safety profile: a comprehensive 2025 review found minimal toxicity with no evidence of carcinogenicity.
Overall, avobenzone is a safe and regulated ingredient used in sunscreen for over 40 years.
Learn more about Butyl MethoxydibenzoylmethaneButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolThis ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.
Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).
In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).
Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.
Shea butter also contains vitamins A and E which may contribute to antioxidant activity.
While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.
This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.
Learn more about Butyrospermum Parkii ButterCitric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAEthylhexyl Salicylate (also called Octisalate or Octyl Salicylate) is an oil-soluble organic UV filter that's been used in sunscreen since the 1950's.
It absorbs UVB light in the 280-320 nm range with a peak absorbance around 306 nm.
You'll often see it paired with other UV filters to boost overall SPF because octisalate is a fairly week filter on its own.
The reason you'll see it so often is because it can help solubilize and stabilize the trickier filters like oxybenzone and avobenzone.
Unlike these filters, octisalate has pretty good photostability and doesn't create skin-damaging free radicals when exposed to sunlight.
The fatty-alcohol part of the molecule also gives it a light, emollient feel so it doubles as a nice texture enhancer.
Usage levels vary around the world:
Safety-wise, this ingredient has a pretty reassuring track record. The EU's Scientific Committee on Consumer Products (SCCP) found very low skin penetration in human skin tests and negative results for irritation, phototoxicity, and photoallergy.
The real-world allergy risk is pretty low too; a 2012 European study of 1,031 people recorded only 2 reactions to it (a rate of 0.19%).
You might have seen scary headlines about sunscreen getting into your blood.
In 2019, the FDA found that several chemical filters can absorb through the skin and show up in the bloodstream at small but measurable levels.
Here's the important part: these tiny levels are just a cutoff the FDA uses to decide which ingredients need more testing and doesn't mean anything harmful was found.
The researchers were clear that the results are no reason to stop wearing sunscreen.
Learn more about Ethylhexyl SalicylateGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinHomosalate is an oil-soluble organic UVB filter that has been a sunscreen staple for decades. Its job is to absorb UVB rays (280-315 nm) and protect your skin against sunburn,
This is one of the more photostable organic UV filters; it holds up pretty well under UV and a 2022 quantum-chemistry study found it stays stable in sunlight.
It's actually so reliable that formulators often pair it with shakier ingredients like oxybenzone and avobenzone. Formulators also use it to help dissolve the other UV filters into the oil phase.
One thing to keep in mind: "stable" isn't the same as "strong". On its own, homosalate is actually a pretty weak UV filter so it's better off as a helpful team player that helps boost overall SPF protection.
The safety picture is a bit nuanced but not scary.
This ingredient has a long track record of being gentle and regulators agree it isn't an irritant; EU's Scientific Committee on Consumer Safety found that homosalate is not considered a skin irritant and doesn't raise eye-irritation flags either.
There's talk about homosalate because your skin absorbs a little bit of it into your bloodstream. A 2020 FDA-backed study found homosalate showed up in people's blood levels at the level where the FDA decides to double check.
The EU's Scientific Committee on Consumer Safety (SCCS) also found small amounts in blood and breast milk. They estimated that about 5% of what you apply gets absorbed through the skin.
Due to the debate about whether it might mess with hormones, the SCCS recommended a maximum limit of 0.5% in most products of 7.3% in face creams/pump sprays.
One important thing to keep in mind: in the US, Homosalate is currently labeled "non-GRASE" by the FDA. This sounds alarming but really just means the FDA wants more data to confirm it's safe. It's not confidently saying this ingredient is harmful.
As of now, homosalate is still completely legal and widely used while that research gets done.
The current maximum limits are:
Learn more about HomosalateParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Steareth-2 is a waxy compound used to emulsify ingredients. It is created from polyethylene glycol and stearyl alcohol. The 2 stands for the number of ethylene oxide units used to create this ingredient.
Due to the low degree of ethoxylation, the molecule stays mostly oil-loving. That's why you'll often see it paired with water-loving steareth-20 or steareth-21 to create elegant emulsions.
In testing, this ingredient was nontoxic in acute oral studies and not a skin irritant or sensitizer.
You might hear concerns about 1,4-dioxane as a byproduct of ethoxylation; this is well-known in the industry and is controlled through purification steps before the ingredient is blended into finished products.
Learn more about Steareth-2Steareth-21 is a nonionic emulsifier made by reacting stearyl alcohol with 21 units of ethylene oxide. It is mainly a cleansing agent and emulsifier.
The "21" in the name just tells you it has a longer water-loving chain. This makes it more gentle and less likely to irritate skin compared to lower-numbered steareths.
You'll most likely see it paired with steareth-2 because the two work together to create stable formulations.
1,4-dioxane is often brought up as a concern but this is usually removed through purification.
Learn more about Steareth-21Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water