La Roche-Posay 10% Pure Niacinamide Serum Versus Sesderma Azelac Ru Crema Gel
Updated on February 08, 2024
Overview
What they are
These products are both reef safe . They have a total of 9 ingredients in common
Cool Features
They both contain exfoliants and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots
Free From
They both do not contain any common allergens, parabens or sulfates
What's Inside
They both contain harsh alcohols, fragrances and silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
La Roche-Posay 10% Pure Niacinamide Serum 29 ingredients
Sesderma Azelac Ru Crema Gel 68 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
La Roche-Posay 10% Pure Niacinamide Serum 29 ingredients
Sesderma Azelac Ru Crema Gel 68 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningNiacinamide
Smoothing
Glycerin
Humectant
Alcohol Denat.
Antimicrobial
Hydroxyethylpiperazine Ethane Sulfonic Acid
BufferingDimethicone
Emollient
Isopropyl Lauroyl Sarcosinate
Skin ConditioningOctyldodecanol
EmollientPEG-20 Methyl Glucose Sesquistearate
Emulsifying
Tin Oxide
Abrasive
Sorbitan Oleate
Emulsifying
Dimethiconol
Emollient
Cetearyl Ethylhexanoate
Emollient
Isohexadecane
EmollientSodium Hyaluronate
Humectant
Phenylethyl Resorcinol
Antioxidant
Poloxamer 338
EmulsifyingAmmonium Polyacryloyldimethyl Taurate
Emulsion StabilisingDisodium EDTA
Isopropyl Myristate
Emollient
Citric Acid
Buffering
Xanthan Gum
EmulsifyingPolysorbate 80
Emulsifying
Acrylamide/Sodium Acryloyldimethyltaurate Copolymer
Emulsion StabilisingTocopherol
Antioxidant
Phenoxyethanol
Preservative
Mica
Cosmetic Colorant
CI 77891
Cosmetic ColorantParfum
Masking
Water, Niacinamide, Glycerin, Alcohol Denat., Hydroxyethylpiperazine Ethane Sulfonic Acid, Dimethicone, Isopropyl Lauroyl Sarcosinate, Octyldodecanol, PEG-20 Methyl Glucose Sesquistearate, Tin Oxide, Sorbitan Oleate, Dimethiconol, Cetearyl Ethylhexanoate, Isohexadecane, Sodium Hyaluronate, Phenylethyl Resorcinol, Poloxamer 338, Ammonium Polyacryloyldimethyl Taurate, Disodium EDTA, Isopropyl Myristate, Citric Acid, Xanthan Gum, Polysorbate 80, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Tocopherol, Phenoxyethanol, Mica, CI 77891, Parfum
Water
Skin ConditioningPropanediol
Solvent
Paraffinum Liquidum
Emollient
Cyclopentasiloxane
Emollient
Lecithin
Emollient
Arachidyl Alcohol
EmollientAlcohol
Antimicrobial
Cetyl Alcohol
Emollient
Undecylenoyl Phenylalanine
Skin ConditioningTranexamic Acid
Astringent
Retinol
Skin Conditioning
Retinal
Skin Conditioning
Palmitoyl Tripeptide-5
Skin Conditioning
Nicotiana Benthamiana Sh-Polypedtide-7
Skin ConditioningNiacin
Smoothing
Morus Alba Root Extract
BleachingGlycyrrhetinic Acid
Skin ConditioningDiacetyl Boldine
Skin ConditioningBellis Perennis Flower Extract
Skin ConditioningBakuchiol
Antimicrobial
Azelaic Acid
Buffering
Ascorbyl Glucoside
Antioxidant
4-Butylresorcinol
Antioxidant
3-O-Ethyl Ascorbic Acid
Skin Conditioning
Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1
Skin Conditioning
Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-2
Skin Conditioning
Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76
Skin Conditioning
Dimethicone/Vinyl Dimethicone Crosspolymer
Skin ConditioningBehenyl Alcohol
Emollient
Arachidyl Glucoside
EmulsifyingTriticum Vulgare Germ Extract
Skin ConditioningPropylene Glycol
Humectant
Carbomer
Emulsion StabilisingCyclohexasiloxane
Emollient
Xanthan Gum
EmulsifyingDimethicone
Emollient
Polysorbate 20
Emulsifying
Citrus Grandis Fruit Extract
Astringent
Sodium Cholate
Skin ConditioningPolysilicone-11
Sodium Hydroxide
BufferingButylene Glycol
Humectant
BHT
Antioxidant
Tocopheryl Acetate
Antioxidant
Disodium EDTA
Tocopherol
Antioxidant
Glyceryl Stearate
Emollient
Ascorbyl Palmitate
Antioxidant
Silica
Abrasive
Sodium Chloride
Masking
Isoceteth-10
EmulsifyingCaprylic/Capric Triglyceride
Masking
Glyceryl Oleate
Emollient
Glycerin
Humectant
Decyl Glucoside
CleansingCitric Acid
Buffering
Tromethamine
BufferingHydrochloric Acid
BufferingBHA
Antioxidant
Hexylene Glycol
EmulsifyingCaprylyl Glycol
EmollientDipotassium Phosphate
BufferingHydroxypropyl Cyclodextrin
MaskingPotassium Phosphate
BufferingPhenoxyethanol
Preservative
Ethylhexylglycerin
Skin ConditioningPotassium Sorbate
Preservative
Parfum
Masking
Water, Propanediol, Paraffinum Liquidum, Cyclopentasiloxane, Lecithin, Arachidyl Alcohol, Alcohol, Cetyl Alcohol, Undecylenoyl Phenylalanine, Tranexamic Acid, Retinol, Retinal, Palmitoyl Tripeptide-5, Nicotiana Benthamiana Sh-Polypedtide-7, Niacin, Morus Alba Root Extract, Glycyrrhetinic Acid, Diacetyl Boldine, Bellis Perennis Flower Extract, Bakuchiol, Azelaic Acid, Ascorbyl Glucoside, 4-Butylresorcinol, 3-O-Ethyl Ascorbic Acid, Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1, Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-2, Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76, Dimethicone/Vinyl Dimethicone Crosspolymer, Behenyl Alcohol, Arachidyl Glucoside, Triticum Vulgare Germ Extract, Propylene Glycol, Carbomer, Cyclohexasiloxane, Xanthan Gum, Dimethicone, Polysorbate 20, Citrus Grandis Fruit Extract, Sodium Cholate, Polysilicone-11, Sodium Hydroxide, Butylene Glycol, BHT, Tocopheryl Acetate, Disodium EDTA, Tocopherol, Glyceryl Stearate, Ascorbyl Palmitate, Silica, Sodium Chloride, Isoceteth-10, Caprylic/Capric Triglyceride, Glyceryl Oleate, Glycerin, Decyl Glucoside, Citric Acid, Tromethamine, Hydrochloric Acid, BHA, Hexylene Glycol, Caprylyl Glycol, Dipotassium Phosphate, Hydroxypropyl Cyclodextrin, Potassium Phosphate, Phenoxyethanol, Ethylhexylglycerin, Potassium Sorbate, Parfum
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinDimethicone is a type of synthetic silicone created from natural materials such as quartz.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeDisodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTACitric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.
If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.
Read more about some other popular AHA's here:
Learn more about Citric AcidXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
La Roche-Posay 10% Pure Niacinamide Serum 29 ingredients
Sesderma Azelac Ru Crema Gel 68 ingredients
Reviews
Here's what our community thinks
La Roche-Posay 10% Pure Niacinamide Serum 29 ingredients
I applied a small amount to a dark spot. The next day I woke up with an inflamed cystic acne that just appeared out of nowhere. Looking at the ingredients now I am not surprised. Very disappointing, why do they make formulas like this???
