Versus

Dr. Dennis Gross Skincare C+ Collagen Deep Cream Versus BioNike Defence Tolerance AR+ Intensive Anti-Redness Treatment

Facial Treatment
Facial Treatment
American Brand United States
Italian Brand Italy

Updated on February 11, 2025

Overview

What they are

These products are both cruelty-free and reef safe facial treatments. They have a total of 11 ingredients in common

Cool Features

They both contain niacinamide, peptides and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, parabens or sulfates

What's Inside

They both contain oils and silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Ingredients Side-by-side

found in both products
C+ Collagen Deep Cream

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Camellia Japonica Seed Oil

Emollient
Oil IconNot safe for Fungal Acne Icon

Oryza Sativa Bran Oil

Emollient
Oil IconNot safe for Fungal Acne Icon

Dimethicone

Emollient
1 / 0 Silicon Icon

Sucrose

Humectant

Pentylene Glycol

Skin Conditioning

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

3-O-Ethyl Ascorbic Acid

Skin Conditioning
Vitamin C IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores Icon

Collagen Amino Acids

Moisturising
Helps with Anti-Aging Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Carnitine Hcl

Humectant

Hydroxyproline

Skin Conditioning

Glycine

Buffering
Helps hydrate Dry Skin Icon

Carnitine

Cleansing

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Dipotassium Glycyrrhizate

Humectant
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Saccharide Isomerate

Humectant

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps with Anti-Aging Icon

Superoxide Dismutase

Antioxidant
Antioxidant IconHelps with Anti-Aging Icon

Leuconostoc/Radish Root Ferment Filtrate

Antimicrobial
Not safe for Fungal Acne Icon

Ubiquinone

Antioxidant
Antioxidant IconHelps with Anti-Aging IconGood for Dark Spots Icon

Aloe Barbadensis Leaf Juice

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon

Lactobacillus Ferment

Skin Conditioning

Undaria Pinnatifida Extract

Skin Conditioning

Glycolic Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Lecithin

Emollient

Biotin

Antiseborrhoeic

Maltodextrin

Absorbent

Caprylyl Glycol

Emollient

1,2-Hexanediol

Skin Conditioning

Carbomer

Emulsion Stabilising
1 / 0

Hydroxyethylcellulose

Emulsion Stabilising

Ammonium Hydroxide

Buffering

Polysorbate 60

Emulsifying
Not safe for Fungal Acne Icon

Potassium Hydroxide

Buffering

Sodium Phytate

Sodium Citrate

Buffering

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Cucumis Sativus Fruit Extract

Emollient

Elettaria Cardamomum Seed Extract

Perfuming
Fragrance Icon

Citrus Aurantium Amara Flower Extract

Refreshing

Cupressus Sempervirens Leaf/Stem Extract

Skin Conditioning

Fucus Vesiculosus Extract

Emollient
Helps hydrate Dry Skin Icon

Pyrus Malus Fruit Extract

Skin Conditioning

Rubus Idaeus Extract

Skin Protecting

Cananga Odorata Flower Extract

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Coffea Arabica Seed Extract

Masking

Rose Extract

Skin Conditioning

Cucumis Melo Fruit Extract

Skin Conditioning

Jasminum Sambac Flower Extract

Masking
Fragrance Icon

Rosmarinus Officinalis Leaf Extract

Antimicrobial

Citrus Aurantium Bergamia Fruit Extract

Skin Conditioning

Salvia Officinalis Leaf Extract

Cleansing

Lavandula Angustifolia Flower/Leaf/Stem Extract

Masking
Fragrance Icon

Santalum Album Wood Extract

Perfuming
Fragrance Icon

Triethyl Citrate

Masking
Fragrance Icon

Phenoxyethanol

Preservative
Preservative Icon

Potassium Sorbate

Preservative
Preservative Icon
Defence Tolerance AR+ Intensive Anti-Redness Treatment

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.
  • It has mild preservative properties.

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.

This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.

Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.

Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.

Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.

Learn more about Pentylene Glycol
Emollient, Masking, Skin Conditioning

Helianthus Annuus Seed Oil is the oil derived from the seeds of a Sunflower. Sunflower seed oil is non-fragrant. It is an emollient, meaning it helps to soften the skin.

Sunflower seed oil contains many fatty acids. The fatty acids found in sunflower seeds include (from highest amount to least): linoleic acid, myristic acid, palmitic acid, stearic acid, arachidic acid, oleic acid, and linolenic acid.

These fatty acids help the skin create ceramides. Ceramides play a role in repairing the skin barrier.

Helianthus Annuus Seed Oil helps moisturize the skin. This in turn helps the skin look more rejuvenated and smoother.

Sunflowers are rich in vitamin E.

Historians believe Indigenous cultures of North America domesticated sunflowers before corn. Thus they relied on sunflower oil for a variety of uses. One such use is moisturizing skin and hair.

Sunflower seed oil may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.

Learn more about Helianthus Annuus Seed Oil
Smoothing

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
Emollient, Skin Conditioning

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan?

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Learn more about Squalane
Antioxidant, Masking, Skin Conditioning

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol
Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

When to use

6 Routines
67% use in am
33% use in pm
83% use every day