Biologique Recherche Lotion P50W Versus Dr. Dennis Gross Skincare DermInfusions™ Fill + Repair Serum
This smoothing toner is formulated around Gluconolactone and Niacinamide to refine skin texture and refine the look of pores.
This barrier-repair serum is formulated around Niacinamide and Ectoin to strengthen the skin barrier and soften the look of wrinkles.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGluconolactone
Skin ConditioningNiacinamide
SmoothingGlycerin
HumectantPropylene Glycol
HumectantLactic Acid
BufferingEthoxydiglycol
HumectantMagnesium Chloride
Malic Acid
BufferingArctium Lappa Root Extract
Skin ConditioningCochlearia Armoracia Root Extract
MaskingQuillaja Saponaria Bark Extract
CleansingArnica Montana Flower Extract
MaskingCapsicum Frutescens Fruit Extract
Skin ConditioningPhytic Acid
Citric Acid
BufferingSodium Lactate
BufferingAllantoin
Skin ConditioningSerine
MaskingSulfur
AntiseborrhoeicVinegar
Sodium Salicylate
PreservativeSorbitol
HumectantTea-Lactate
HumectantUrea
BufferingSodium Benzoate
MaskingSodium Bisulfite
AntioxidantWater, Gluconolactone, Niacinamide, Glycerin, Propylene Glycol, Lactic Acid, Ethoxydiglycol, Magnesium Chloride, Malic Acid, Arctium Lappa Root Extract, Cochlearia Armoracia Root Extract, Quillaja Saponaria Bark Extract, Arnica Montana Flower Extract, Capsicum Frutescens Fruit Extract, Phytic Acid, Citric Acid, Sodium Lactate, Allantoin, Serine, Sulfur, Vinegar, Sodium Salicylate, Sorbitol, Tea-Lactate, Urea, Sodium Benzoate, Sodium Bisulfite
Water
Skin ConditioningGlycerin
HumectantNiacinamide
SmoothingButylene Glycol
HumectantEctoin
Skin ConditioningSodium Hyaluronate
HumectantHydrolyzed Sodium Hyaluronate
Skin ConditioningSodium Acetylated Hyaluronate
HumectantSodium Hyaluronate Crosspolymer
HumectantAcetyl Hexapeptide-8
HumectantPalmitoyl Tripeptide-1
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningOligopeptide-2
Skin ConditioningSaccharide Isomerate
HumectantCamellia Sinensis Leaf Extract
AntimicrobialCentella Asiatica Extract
CleansingVitis Vinifera Seed Extract
AntimicrobialSodium Carboxymethyl Beta-Glucan
CleansingBakuchiol
AntimicrobialInonotus Obliquus Extract
Skin ConditioningTetrahydrocurcumin
AntioxidantCeramide NP
Skin ConditioningCeramide AP
Skin ConditioningCeramide EOP
Skin ConditioningPhospholipids
Skin ConditioningSphingolipids
EmollientPhytosphingosine
Skin ConditioningColloidal Oatmeal
AbsorbentBisabolol
AntioxidantSuperoxide Dismutase
AntioxidantTerminalia Ferdinandiana Fruit Extract
AntioxidantSodium PCA
HumectantGlutathione
Squalane
EmollientCaffeine
Skin ConditioningPanthenol
Skin ConditioningButyrospermum Parkii Butter
Skin ConditioningAloe Barbadensis Leaf Juice
Skin ConditioningArnica Montana Flower Extract
MaskingAcetyl Glutamine
Skin ConditioningBifida Ferment Lysate
Skin ConditioningChamomilla Recutita Flower Extract
MaskingWithania Somnifera Root Extract
Skin ConditioningGlycolic Acid
BufferingMandelic Acid
AntimicrobialLactobionic Acid
BufferingEthylhexylglycerin
Skin ConditioningCoco-Glucoside
CleansingLauryl Glucoside
CleansingDecyl Glucoside
CleansingPolyglyceryl-10 Laurate
Skin ConditioningDiheptyl Succinate
EmollientDimethicone
EmollientPentylene Glycol
Skin ConditioningSodium Lauroyl Lactylate
EmulsifyingPvm/Ma Decadiene Crosspolymer
Vp/Va Copolymer
Xanthan Gum
EmulsifyingPotassium Hydroxide
BufferingPolysorbate 20
EmulsifyingDimethicone Crosspolymer
Emulsion StabilisingCarbomer
Emulsion StabilisingCholesterol
EmollientCapryloyl Glycerin/Sebacic Acid Copolymer
Skin ConditioningLeuconostoc/Radish Root Ferment Filtrate
AntimicrobialSodium Citrate
BufferingCitric Acid
BufferingSodium Metasilicate
BufferingGluconolactone
Skin ConditioningTetrasodium Glutamate Diacetate
Caprylic/Capric Triglyceride
MaskingJasminum Officinale Flower/Leaf Extract
MaskingVitis Vinifera Fruit Extract
Skin ConditioningEugenia Caryophyllus Flower Extract
AstringentLavandula Angustifolia Flower/Leaf/Stem Extract
MaskingRaspberry Ketone
MaskingPhenoxyethanol
PreservativePotassium Sorbate
PreservativeWater, Glycerin, Niacinamide, Butylene Glycol, Ectoin, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Sodium Hyaluronate Crosspolymer, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Oligopeptide-2, Saccharide Isomerate, Camellia Sinensis Leaf Extract, Centella Asiatica Extract, Vitis Vinifera Seed Extract, Sodium Carboxymethyl Beta-Glucan, Bakuchiol, Inonotus Obliquus Extract, Tetrahydrocurcumin, Ceramide NP, Ceramide AP, Ceramide EOP, Phospholipids, Sphingolipids, Phytosphingosine, Colloidal Oatmeal, Bisabolol, Superoxide Dismutase, Terminalia Ferdinandiana Fruit Extract, Sodium PCA, Glutathione, Squalane, Caffeine, Panthenol, Butyrospermum Parkii Butter, Aloe Barbadensis Leaf Juice, Arnica Montana Flower Extract, Acetyl Glutamine, Bifida Ferment Lysate, Chamomilla Recutita Flower Extract, Withania Somnifera Root Extract, Glycolic Acid, Mandelic Acid, Lactobionic Acid, Ethylhexylglycerin, Coco-Glucoside, Lauryl Glucoside, Decyl Glucoside, Polyglyceryl-10 Laurate, Diheptyl Succinate, Dimethicone, Pentylene Glycol, Sodium Lauroyl Lactylate, Pvm/Ma Decadiene Crosspolymer, Vp/Va Copolymer, Xanthan Gum, Potassium Hydroxide, Polysorbate 20, Dimethicone Crosspolymer, Carbomer, Cholesterol, Capryloyl Glycerin/Sebacic Acid Copolymer, Leuconostoc/Radish Root Ferment Filtrate, Sodium Citrate, Citric Acid, Sodium Metasilicate, Gluconolactone, Tetrasodium Glutamate Diacetate, Caprylic/Capric Triglyceride, Jasminum Officinale Flower/Leaf Extract, Vitis Vinifera Fruit Extract, Eugenia Caryophyllus Flower Extract, Lavandula Angustifolia Flower/Leaf/Stem Extract, Raspberry Ketone, Phenoxyethanol, Potassium Sorbate
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Arnica Montana Flower is more commonly known as Wolf's Bane. While this flower has been used in traditional medicine, its skin benefits are in question.
The FDA considers Wolf's Bane to be an unsafe herb. They advise against taking it orally or applying it to broken skin.
Wolf's Bane has been said to have anti-inflammatory properties. However, studies are conflicting about whether this is true.
According to the Final report on the safety assessment of Arnica montana, this plant has not been found to cause dermal irritation.
This flower contains numerous fatty acids such as palmitic, linoleic, myristic, and linolenic acids. The presence and amount of fatty acids depends on where the flower is harvested.
Like other flowers, this ingredient has a natural fragrance. It can also be used to mask, or cover, the unpleasant scents from other ingredients.
Learn more about Arnica Montana Flower ExtractCitric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidGluconolactone is a PHA. PHAs are a great gentle alternative to traditional AHAs.
When applied, Gluconolactone has the same affect on skin as AHAs such as lactic acid. It helps dissolve the dead skin cells in the top layer of your skin. This improves texture and brightens the skin.
PHAs are more gentle than AHAs due to their larger structure. They do not penetrate as deeply as AHAs and take a longer time to dissolve dead cells. Studies show PHAs do not cause as much irritation.
Gluconolactone has some interesting properties:
In a 2004 study, Gluconolactone was found to prevent UV damage in mouse skin cells and has not been found to increase sun sensitivity. However, we still recommend wearing SPF daily.
This ingredient is is an created by reacting gluconic acid with an alcohol.
Learn more about GluconolactoneGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water