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Product Comparison

Here's our complete breakdown comparing the ingredients, attributes, and more of Peter Thomas Roth Peptide 21 Wrinkle Resist Serum versus Peter Thomas Roth Pro Strength Vitamin A/C/E Retinoid Treatment .

Published on March 01, 2023

Overview

What they are

These products are both reef safe . They have a total of 10 ingredients in common

Cool Features

They both contain exfoliants, hyaluronic acid, retinoid, Vitamin C and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any common allergens or parabens

What's Inside

They both contain silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that need an update? Let us know.

Serum American Brand United States
Facial Treatment American Brand United States

Serum

Serums are highly concentrated with ingredients to provide skin with benefits. They should be used after cleansing and before moisturizing.

Facial Treatment

Facial treatments are specially designed to treat a skin concern. Acne treatments and anti-aging products are common examples of facial treatments.

Price

Shop

Buy Peptide 21 Wrinkle Resist Serum

Starts at $57.95
Shop

Buy Pro Strength Vitamin A/C/E Retinoid Treatment

Starts at $560.00

Ingredient Info

Click any item below to learn more and view relevant ingredients.
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free

At a glance

Click on any of the items below to learn more

Notable Ingredients

Retinoid
Vitamin C
Vitamin E
Exfoliators
Hyaluronic Acid

Benefits

Hydrating (2)
Good For Oily Skin
Redness Reducing
Skin Texture (2)
Reduces Large Pores
Anti-Aging (2)
Dark Spots (2)
Scar Healing (2)
Acne Fighting
Brightening (3)

Concerns

Drying
May Worsen Oily Skin
Acne Trigger
Irritating
Rosacea
Eczema

Notable Ingredients

AHA
Retinoid
Vitamin C
Vitamin E
Exfoliators
Hyaluronic Acid

Benefits

Hydrating (2)
Good For Oily Skin
Redness Reducing
Skin Texture (3)
Reduces Large Pores (2)
Anti-Aging (2)
Dark Spots (2)
Scar Healing (3)
Acne Fighting
Brightening (3)

Concerns

Drying
May Worsen Oily Skin
Irritating (2)
Rosacea (2)
Eczema
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Ingredients Compared

Ingredients that are highlighted in purple are present in both products.

Ingredients Side-by-side

Ingredients that are highlighted in purple are present in both products.

Learn more about what what Com. / Irr. ratings are

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Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1
What it does: Skin Conditioning, Solvent
Community Rating: Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

Peter Thomas Roth Peptide 21 Wrinkle Resist Serum contains this as ingredient number 1.

Peter Thomas Roth Pro Strength Vitamin A/C/E Retinoid Treatment contains this as ingredient number 1.

2
What it does: Emollient, Skin Conditioning
Community Rating: Loved

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan? This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Learn more about Squalane

Peter Thomas Roth Peptide 21 Wrinkle Resist Serum contains this as ingredient number 5.

Peter Thomas Roth Pro Strength Vitamin A/C/E Retinoid Treatment contains this as ingredient number 18.

3
What it does: Humectant, Skin Conditioning
Community Rating: Loved

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate

Peter Thomas Roth Peptide 21 Wrinkle Resist Serum contains this as ingredient number 26.

Peter Thomas Roth Pro Strength Vitamin A/C/E Retinoid Treatment contains this as ingredient number 19.

4
What it does: Antioxidant, Skin Conditioning
Community Rating: Liked

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate

Peter Thomas Roth Peptide 21 Wrinkle Resist Serum contains this as ingredient number 27.

Peter Thomas Roth Pro Strength Vitamin A/C/E Retinoid Treatment contains this as ingredient number 3.

5
What it does: Antioxidant, Buffering, Masking, Skin Conditioning
Community Rating: Loved

Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.

Not only is vitamin C great for your overall health and immune system, it also has plenty of benefits on your skin.

Vitamin C is best used for brightening skin. It improves dark spots, acne scars, and hyperpigmentation. This is because it blocks the process of skin darkening when exposed to UV.

Remember: Vitamin C should not replace sunscreen!

Your skin uses vitamin C to build collagen. Collagen is one key component in having a strong skin barrier and plump skin. Vitamin C also plays a role in regulating collagen, thus making it effective in improving wrinkles and fine lines.

Ascorbic acid shows potent antioxidant activity. As an antioxidant, it helps fight free-radicals. Free-radicals are molecules that may damage your skin cells. These antioxidants also protect skin against UV damage.

The best formulations include Vitamin E and/or ferulic acid. These two ingredients help stabilize and provide a boost in the benefits of ascorbic acid. This is because ascorbic acid becomes unstable when exposed to UV and air. In fact, you can tell your ascorbic acid has oxidized when it turns an orange-yellow color.

Ascorbic acid is generally compatible with other ingredients. However, using ascorbic acid with other active ingredients might cause irritation. Two ingredients: copper ions and benzoyl peroxide, will inactivate ascorbic acid completely.

Read more about other types of Vitamin C:

Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.

Learn more about Ascorbic Acid

Peter Thomas Roth Peptide 21 Wrinkle Resist Serum contains this as ingredient number 29.

Peter Thomas Roth Pro Strength Vitamin A/C/E Retinoid Treatment contains this as ingredient number 16.

6
What it does: Solvent
Community Rating: Disliked

Dimethyl Isosorbide is a solvent and helps deliver actives into your skin. It is created from sorbitol.

As a solvent, dimethyl isosorbide helps dissolve other ingredients. This helps ensure even distribution of an ingredient. It may also be used to decrease the thickness of a product.

Studies show dimethyl isosorbide is able to penetrate skin to deliver other ingredients into the skin, making them more effective.

Learn more about Dimethyl Isosorbide

Peter Thomas Roth Peptide 21 Wrinkle Resist Serum contains this as ingredient number 37.

Peter Thomas Roth Pro Strength Vitamin A/C/E Retinoid Treatment contains this as ingredient number 2.

7
What it does: Abrasive, Absorbent
Community Rating: Disliked

Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.

Silica is often used for absorption and can help reduce shine when products are applied. Silica occurs in naturally in materials like clay and sandstone, and it can also be produced synthetically.

Silica is present naturally within the skin during collagen production and when reducing inflammation.

Learn more about Silica

Peter Thomas Roth Peptide 21 Wrinkle Resist Serum contains this as ingredient number 50.

Peter Thomas Roth Pro Strength Vitamin A/C/E Retinoid Treatment contains this as ingredient number 30.

8
What it does: Preservative
Community Rating: Disliked

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

Potassium sorbate is potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

Potassium sorbate is often used with stronger preservatives.

Learn more about Potassium Sorbate

Peter Thomas Roth Peptide 21 Wrinkle Resist Serum contains this as ingredient number 54.

Peter Thomas Roth Pro Strength Vitamin A/C/E Retinoid Treatment contains this as ingredient number 26.

9
What it does: Masking, Preservative
Community Rating: Disliked

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

Sodium Benzoate is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Learn more about Sodium Benzoate

Peter Thomas Roth Peptide 21 Wrinkle Resist Serum contains this as ingredient number 55.

Peter Thomas Roth Pro Strength Vitamin A/C/E Retinoid Treatment contains this as ingredient number 34.

10
What it does: Preservative
Community Rating: Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Peter Thomas Roth Peptide 21 Wrinkle Resist Serum contains this as ingredient number 56.

Peter Thomas Roth Pro Strength Vitamin A/C/E Retinoid Treatment contains this as ingredient number 38.

Here's what our community thinks of the ingredients in these two products.

50% are loved or liked
7% have mixed ratings
30% are disliked or very disliked
13% have no rating yet
24% are loved or liked
11% have mixed ratings
50% are disliked or very disliked
16% have no rating yet

Usage

Here's some more info on how this product is used by our community.

Alternatives

Our Dupe Finder has found 7 potential alternatives that have similar ingredients to Peter Thomas Roth Peptide 21 Wrinkle Resist Serum.

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Our Dupe Finder has found 3 potential alternatives that have similar ingredients to Peter Thomas Roth Pro Strength Vitamin A/C/E Retinoid Treatment.

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