Niod Fractionated Eye Contour Concentrate Serum Versus Peter Thomas Roth Peptide 21 Wrinkle Resist Serum
Updated on February 06, 2025
Overview
What they are
These products are both reef safe . They have a total of 15 ingredients in common
Cool Features
They both contain hyaluronic acid, peptides and Vitamin C
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any parabens
What's Inside
They both contain sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Niod Fractionated Eye Contour Concentrate Serum 80 ingredients
Peter Thomas Roth Peptide 21 Wrinkle Resist Serum 56 ingredients
What's inside
What's inside
At a glance
Click on any of the items below to learn more
Niod Fractionated Eye Contour Concentrate Serum 80 ingredients
Peter Thomas Roth Peptide 21 Wrinkle Resist Serum 56 ingredients
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
Humectant
Butylene Glycol
Humectant
Propanediol
Solvent
Hydrolyzed Yeast Extract
Skin ConditioningAlbizia Julibrissin Bark Extract
MaskingNiacinamide
Smoothing
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Palmitoyl Tripeptide-38
Skin Conditioning
Acetyl Hexapeptide-8
Humectant
Acetyl Tetrapeptide-5
Humectant
Decapeptide-22
Skin Conditioning
Oligopeptide-78
Skin Conditioning
Palmitoyl Decapeptide-21
Skin Conditioning
Palmitoyl Hexapeptide-52
Skin Conditioning
Zinc Palmitoyl Nonapeptide-14
Skin Conditioning
Palmitoyl Tetrapeptide-50
Skin Conditioning
Pentapeptide-18
Skin Conditioning
Acetyl Hexapeptide-30
Skin Conditioning
Heptapeptide-15 Palmitate
Skin Conditioning
Palmitoyl Heptapeptide-18
Skin Conditioning
S-Mu-Conotoxin Cniiic Acetate
Skin ConditioningSodium Hyaluronate
Humectant
Darutoside
Skin ConditioningEpigallocatechin Gallatyl Glucoside
Antioxidant
Gallyl Glucoside
Antioxidant
Ascorbyl Glucoside
Antioxidant
Zinc PCA
Humectant
Methylglucoside Phosphate
Skin ConditioningDisodium Acetyl Glucosamine Phosphate
Skin ConditioningCopper Lysinate/Prolinate
Skin ConditioningHydroxypropyl Cyclodextrin
MaskingSuperoxide Dismutase
Antioxidant
Escin
TonicAscorbic Acid
Antioxidant
Ammonium Glycyrrhizate
MaskingPolyglucuronic Acid
Skin ConditioningAscophyllum Nodosum Extract
Skin ConditioningAsparagopsis Armata Extract
Skin ProtectingFraxinus Excelsior Bark Extract
Skin ConditioningOlea Europaea Leaf Extract
Perfuming
Polypodium Vulgare Rhizome Extract
HumectantCetraria Islandica Thallus Extract
HumectantSphagnum Magellanicum Extract
Skin ConditioningRuscus Aculeatus Root Extract
AstringentCentella Asiatica Extract
Cleansing
Calendula Officinalis Flower Extract
Masking
Arginine
Masking
Panthenol
Skin Conditioning
Hydrolyzed Rice Protein
Skin ConditioningGlycine Soja Protein
EmulsifyingHydrolyzed Wheat Protein
Skin ConditioningHydrolyzed Yeast Protein
Skin ConditioningLecithin
Emollient
Polyacrylate Crosspolymer-6
Emulsion StabilisingXanthan Gum
EmulsifyingCetyl Hydroxyethylcellulose
Emulsion StabilisingSilanetriol
Sodium Dextran Sulfate
Gel Forming
Sorbitol
Humectant
Pentylene Glycol
Skin ConditioningDimethyl Isosorbide
SolventCitric Acid
Buffering
Glycolic Acid
Buffering
Lactic Acid
Buffering
Lactic Acid/Glycolic Acid Copolymer
Skin ConditioningPPG-26-Buteth-26
Skin ConditioningPolyvinyl Alcohol
PEG-40 Hydrogenated Castor Oil
Emulsifying
Propyl Gallate
Antioxidant
Potassium Sorbate
Preservative
Caprylyl Glycol
Emollient
Glyceryl Caprylate
EmollientEthylhexylglycerin
Skin ConditioningSodium Benzoate
Masking
Benzyl Alcohol
Perfuming
Phenylpropanol
Masking
Dehydroacetic Acid
Preservative
Phenoxyethanol
Preservative
Chlorphenesin
Antimicrobial
Water, Glycerin, Butylene Glycol, Propanediol, Hydrolyzed Yeast Extract, Albizia Julibrissin Bark Extract, Niacinamide, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tripeptide-38, Acetyl Hexapeptide-8, Acetyl Tetrapeptide-5, Decapeptide-22, Oligopeptide-78, Palmitoyl Decapeptide-21, Palmitoyl Hexapeptide-52, Zinc Palmitoyl Nonapeptide-14, Palmitoyl Tetrapeptide-50, Pentapeptide-18, Acetyl Hexapeptide-30, Heptapeptide-15 Palmitate, Palmitoyl Heptapeptide-18, S-Mu-Conotoxin Cniiic Acetate, Sodium Hyaluronate, Darutoside, Epigallocatechin Gallatyl Glucoside, Gallyl Glucoside, Ascorbyl Glucoside, Zinc PCA, Methylglucoside Phosphate, Disodium Acetyl Glucosamine Phosphate, Copper Lysinate/Prolinate, Hydroxypropyl Cyclodextrin, Superoxide Dismutase, Escin, Ascorbic Acid, Ammonium Glycyrrhizate, Polyglucuronic Acid, Ascophyllum Nodosum Extract, Asparagopsis Armata Extract, Fraxinus Excelsior Bark Extract, Olea Europaea Leaf Extract, Polypodium Vulgare Rhizome Extract, Cetraria Islandica Thallus Extract, Sphagnum Magellanicum Extract, Ruscus Aculeatus Root Extract, Centella Asiatica Extract, Calendula Officinalis Flower Extract, Arginine, Panthenol, Hydrolyzed Rice Protein, Glycine Soja Protein, Hydrolyzed Wheat Protein, Hydrolyzed Yeast Protein, Lecithin, Polyacrylate Crosspolymer-6, Xanthan Gum, Cetyl Hydroxyethylcellulose, Silanetriol, Sodium Dextran Sulfate, Sorbitol, Pentylene Glycol, Dimethyl Isosorbide, Citric Acid, Glycolic Acid, Lactic Acid, Lactic Acid/Glycolic Acid Copolymer, PPG-26-Buteth-26, Polyvinyl Alcohol, PEG-40 Hydrogenated Castor Oil, Propyl Gallate, Potassium Sorbate, Caprylyl Glycol, Glyceryl Caprylate, Ethylhexylglycerin, Sodium Benzoate, Benzyl Alcohol, Phenylpropanol, Dehydroacetic Acid, Phenoxyethanol, Chlorphenesin
Water
Skin ConditioningGlycerin
Humectant
Rosa Centifolia Flower Water
Skin ConditioningIsopropyl Myristate
Emollient
Squalane
Emollient
Mannitol
Humectant
Butylene Glycol
Humectant
Natto Gum
Tripeptide-10 Citrulline
Skin Conditioning
Acetyl Octapeptide-3
Humectant
Palmitoyl Hexapeptide-12
Skin Conditioning
Acetyl Tetrapeptide-11
Skin Conditioning
Acetyl Hexapeptide-8
Humectant
Acetyl Hexapeptide-1
Skin Conditioning
Palmitoyl Oligopeptide
Cleansing
Acetyl Tetrapeptide-9
Skin Conditioning
Acetyl Tetrapeptide-2
Skin Conditioning
Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Hexapeptide-11
Skin Conditioning
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Palmitoyl Tripeptide-5
Skin Conditioning
Trifluoroacetyl Tripeptide-2
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Sodium Polyglutamate
HumectantSodium Hyaluronate
Humectant
Tocopheryl Acetate
Antioxidant
Retinyl Palmitate
Skin Conditioning
Ascorbic Acid
Antioxidant
Hydrolyzed Soy Protein
Humectant
Hydrolyzed Wheat Protein
Skin ConditioningLecithin
Emollient
Pseudoalteromonas Ferment Extract
Humectant
Acrylates Copolymer
Magnesium Chloride
Polysorbate 20
Emulsifying
Dimethyl Isosorbide
SolventAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingLeuconostoc/Radish Root Ferment Filtrate
Antimicrobial
PEG-8 Dimethicone
Emulsifying
Disodium Phosphate
BufferingCarbomer
Emulsion StabilisingDextran
Sodium Lactate
BufferingTetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
Skin ConditioningXanthan Gum
EmulsifyingTriethanolamine
BufferingSodium Phosphate
BufferingOctyldodecanol
Emollient
Silica
Abrasive
Sodium Propoxyhydroxypropyl Thiosulfate Silica
Sodium Hydroxide
BufferingCaprylyl Glycol
Emollient
Potassium Sorbate
Preservative
Sodium Benzoate
Masking
Phenoxyethanol
Preservative
Water, Glycerin, Rosa Centifolia Flower Water, Isopropyl Myristate, Squalane, Mannitol, Butylene Glycol, Natto Gum, Tripeptide-10 Citrulline, Acetyl Octapeptide-3, Palmitoyl Hexapeptide-12, Acetyl Tetrapeptide-11, Acetyl Hexapeptide-8, Acetyl Hexapeptide-1, Palmitoyl Oligopeptide, Acetyl Tetrapeptide-9, Acetyl Tetrapeptide-2, Tripeptide-1, Palmitoyl Tetrapeptide-7, Hexapeptide-11, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tripeptide-5, Trifluoroacetyl Tripeptide-2, Palmitoyl Tripeptide-1, Sodium Polyglutamate, Sodium Hyaluronate, Tocopheryl Acetate, Retinyl Palmitate, Ascorbic Acid, Hydrolyzed Soy Protein, Hydrolyzed Wheat Protein, Lecithin, Pseudoalteromonas Ferment Extract, Acrylates Copolymer, Magnesium Chloride, Polysorbate 20, Dimethyl Isosorbide, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Leuconostoc/Radish Root Ferment Filtrate, PEG-8 Dimethicone, Disodium Phosphate, Carbomer, Dextran, Sodium Lactate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Xanthan Gum, Triethanolamine, Sodium Phosphate, Octyldodecanol, Silica, Sodium Propoxyhydroxypropyl Thiosulfate Silica, Sodium Hydroxide, Caprylyl Glycol, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acetyl Hexapeptide-8, commonly known as Argireline, is a popular peptide in skincare. It’s often referred to as a “Botox-like” ingredient because it helps reduce muscle movement.
By relaxing these micro-movements, Argireline may help minimize the appearance of fine lines and wrinkles. That said, it’s not as powerful as Botox, and research on its long-term effectiveness is still limited.
Beyond smoothing, Argireline may also support collagen production. Collagen is the protein that helps keep your skin firm, bouncy, and well-hydrated by strengthening the skin barrier.
So while Argireline isn’t a miracle fix, it can be a helpful addition to a routine focused on both prevention and skin health.
Read more about other common types of peptides here:
Learn more about Acetyl Hexapeptide-8Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.
Not only is vitamin C great for your overall health and immune system, it also has plenty of benefits on your skin.
Vitamin C is best used for brightening skin. It improves dark spots, acne scars, and hyperpigmentation. This is because it blocks the process of skin darkening when exposed to UV.
Remember: Vitamin C should not replace sunscreen!
Your skin uses vitamin C to build collagen. Collagen is one key component in having a strong skin barrier and plump skin. Vitamin C also plays a role in regulating collagen, thus making it effective in improving wrinkles and fine lines.
Ascorbic acid shows potent antioxidant activity. As an antioxidant, it helps fight free-radicals. Free-radicals are molecules that may damage your skin cells. These antioxidants also protect skin against UV damage.
The best formulations include Vitamin E and/or ferulic acid. These two ingredients help stabilize and provide a boost in the benefits of ascorbic acid. This is because ascorbic acid becomes unstable when exposed to UV and air. In fact, you can tell your ascorbic acid has oxidized when it turns an orange-yellow color.
Ascorbic acid is generally compatible with other ingredients. However, using ascorbic acid with other active ingredients might cause irritation. Two ingredients: copper ions and benzoyl peroxide, will inactivate ascorbic acid completely.
Read more about other types of Vitamin C:
Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.
Learn more about Ascorbic AcidButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCaprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolDimethyl Isosorbide is a solvent and helps deliver actives into your skin. It is created from sorbitol.
As a solvent, dimethyl isosorbide helps dissolve other ingredients. This helps ensure even distribution of an ingredient. It may also be used to decrease the thickness of a product.
Studies show dimethyl isosorbide is able to penetrate skin to deliver other ingredients into the skin, making them more effective.
Learn more about Dimethyl IsosorbideThis small molecule peptide has similar benefits to Argireline, the "botox" peptide.
According to the manufacturer, this peptide mimics snake venom to freeze muscles. This prevents muscle movement and contractions to prohibit the formation of fine lines and wrinkles.
While this seems promising, research is lacking in proving this ingredient to be as effective as botox.
Learn more about Dipeptide Diaminobutyroyl Benzylamide DiacetateGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinWe don't have a description for Hydrolyzed Wheat Protein yet.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.
This ingredient has emollient and emulsifying properties.
As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.
As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.
This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.
Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.
We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.
Some other names for this ingredient include soy lecithin and deoiled soy lecithin.
Learn more about LecithinPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Learn more about Potassium SorbateSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumIngredient Ratings
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When to use
Niod Fractionated Eye Contour Concentrate Serum 80 ingredients
Peter Thomas Roth Peptide 21 Wrinkle Resist Serum 56 ingredients
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